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TVLLFAPTPMAAAEIGQRVAQADAYLATRPGVVGYVLRDRTTGETHRNEVANTMMWTASTIKLAMVVDLL TRARAGQITLTPADRQLMADMMHSSDSGAADTLWERYSGPDNMAFNRNFATYGLTSLQPQPGFSSTHPYW GFQKATSEDLDRLMNYTLTSLPAAETAAIVSEMQHLDANQQWGVWGAGAAMTPGNKNGWSQEQGGWVVNS VGFAGPRQRYTLAIMNSLNGEGGYDDGVETTTRLARILLAPA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3689 | - | - | 100% (253) | hypothetical protein Mvan_3689 |
| M. vanbaalenii PYR-1 | Mvan_5916 | - | 1e-14 | 31.47% (232) | beta-lactamase |
| M. vanbaalenii PYR-1 | Mvan_2191 | - | 4e-11 | 28.38% (229) | putative alanine rich lipoprotein LppW |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2929 | lppW | 5e-14 | 29.28% (222) | alanine rich lipoprotein LppW |
| M. gilvum PYR-GCK | Mflv_2833 | - | 1e-137 | 92.49% (253) | hypothetical protein Mflv_2833 |
| M. tuberculosis H37Rv | Rv2905 | lppW | 5e-14 | 29.28% (222) | alanine rich lipoprotein LppW |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3225 | - | 2e-15 | 28.51% (228) | putative lipoprotein LppW precursor |
| M. marinum M | MMAR_1803 | lppW | 1e-12 | 28.51% (221) | alanine rich lipoprotein LppW |
| M. avium 104 | MAV_3761 | - | 2e-11 | 28.44% (225) | LppW protein |
| M. smegmatis MC2 155 | MSMEG_6822 | - | 1e-16 | 29.82% (228) | beta-lactamase |
| M. thermoresistible (build 8) | TH_1402 | lppW | 1e-12 | 28.37% (215) | PROBABLE CONSERVED ALANINE RICH LIPOPROTEIN LPPW |
| M. ulcerans Agy99 | MUL_2051 | lppW | 7e-13 | 28.51% (221) | alanine rich lipoprotein LppW |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6822|M.smegmatis_MC2_155 MRRRQPKSVMTGMAVVACAALLVSGCTAPAGGAPPAVEHTPQA-------
TH_1402|M.thermoresistible__bu ----------------------LSTTSTPX--------------------
Mb2929|M.bovis_AF2122/97 MRARPLTLLTALAAVTLVV---VAGCEARVEAEAYSAADRISSRPQARPQ
Rv2905|M.tuberculosis_H37Rv MRARPLTLLTALAAVTLVV---VAGCEARVEAEAYSAADRISSRPQARPQ
MMAR_1803|M.marinum_M MRARPLTMLTAAAAVALVVSLVLTGCEAKVQAKAYGTDDRESSRQQSQPQ
MUL_2051|M.ulcerans_Agy99 MRARPLTMLTAAAAVALVVSLVLTGCEAKVQAKAYGTDDRESSRQQSQPQ
MAV_3761|M.avium_104 MRVRPLTLFTATAAVTLLI---AAGSEALVQAKVYHLPVAAPVRVLTQPP
MAB_3225|M.abscessus_ATCC_1997 MRGQHLFVGLTLTAATALT----SGCVASVRSDPATPVLAVVSAP-----
Mvan_3689|M.vanbaalenii_PYR-1 --------------MTVLLFAPTPMAAAEIG-------------------
Mflv_2833|M.gilvum_PYR-GCK --------------MTVLLCAPTPVATAEIG-------------------
. :
MSMEG_6822|M.smegmatis_MC2_155 ----------TVAPPAAPPPVQPPASFAGLDARMQQATADAAASGATIEA
TH_1402|M.thermoresistible__bu -----------------------------------QATADAAASGADITI
Mb2929|M.bovis_AF2122/97 PQ-PVELLLRAITPPRAPAAS-PNVGFGELPTRVRQATDEAAAMGATLSV
Rv2905|M.tuberculosis_H37Rv PQ-PVELLLRAITPPRAPAAS-PNVGFGELPTRVRQATDEAAAMGATLSV
MMAR_1803|M.marinum_M QQQLIELLLRAITPPEDPAALLPSAGLVGVQERIQRATEEAAAKGATITV
MUL_2051|M.ulcerans_Agy99 QQQLIELLLRAITPPEDPAALLPSAGLVGVQERIQRATEEAAAKGATITV
MAV_3761|M.avium_104 PPQSAALMLEAATPPQPPQAL-PNAGFAQLPARIQQAADQAAASGAALSV
MAB_3225|M.abscessus_ATCC_1997 ----------AETPPVFEVES--PTSFETLPERTTAATTQAKSAGATLTA
Mvan_3689|M.vanbaalenii_PYR-1 -------------------------------QRVAQADAYLATRPGVVGY
Mflv_2833|M.gilvum_PYR-GCK -------------------------------QRIAQADAYLATRPGTVGY
* : . :
MSMEG_6822|M.smegmatis_MC2_155 VVLDRNTGEVVSNGSN-KPFPIASVVKLFIADDLLLQESEGKTELSPADR
TH_1402|M.thermoresistible__bu AVLDRSTGQAASSGGD-TPFPIASVVKLFIADDLLLQESEGKTQLSDADR
Mb2929|M.bovis_AF2122/97 AVLDRATGQLVSNGNT-QIIATASVAKLFIADDLLLAEAEGKVTLSPEDH
Rv2905|M.tuberculosis_H37Rv AVLDRATGQLVSNGNT-QIIATASVAKLFIADDLLLAEAEGKVTLSPEDH
MMAR_1803|M.marinum_M AILDRATHQLVSNGKT-SIIATASVSKLFIADELLLRASQGKTTLSAQDR
MUL_2051|M.ulcerans_Agy99 AILDRATHQLVSNGKT-SIIATASVSKLFIADELLLRASQGKTTLSAQDR
MAV_3761|M.avium_104 AILDRGTHQLVSIGNG-QIVGTASVAKLFIADDLLLHQAEGKAALSADDR
MAB_3225|M.abscessus_ATCC_1997 VIKDRASGAVVSNGNN-STIAIASVAKLFIADDLLMRESQGEVTLTPADR
Mvan_3689|M.vanbaalenii_PYR-1 VLRDRTTGETHRNEVANTMMWTASTIKLAMVVDLLTRARAGQITLTPADR
Mflv_2833|M.gilvum_PYR-GCK VLRDRTTGQAHRNDAATTMMWTASTIKLAMVVDLLTRARAGQIALTPADR
.: ** : . **. ** :. :** *: *: *:
MSMEG_6822|M.smegmatis_MC2_155 KSLDVMLRSSDDSAAQMFWDRLGG--NAVISRIKARYGLPGTIAP-----
TH_1402|M.thermoresistible__bu AALDLMLRSSDDGAAQMFWDRNGG--NAVISRIVARYGLTGTTPP-----
Mb2929|M.bovis_AF2122/97 HALDVMLQSSDDGAAERFWSQDGG--NAVVTQVARRYGLRSTAPP-----
Rv2905|M.tuberculosis_H37Rv HALDVMLQSSDDGAAERFWSQDGG--NAVVTQVARRYGLRSTAPP-----
MMAR_1803|M.marinum_M QALDNMLRSSDDGAAEQFWGELGG--DAIVTEIATRYGLAATAPP-----
MUL_2051|M.ulcerans_Agy99 QALDNMLRSSDDGAAEQFWGELGG--DAIVTEIATRYGLAATAPP-----
MAV_3761|M.avium_104 QALDIMLQSSDDGAAERFWGQGGG--AAIISEVASRYGLTSTTPP-----
MAB_3225|M.abscessus_ATCC_1997 AAFDRMLQSSDDSAAEVFWQRGGG--NSIITRVAARYGLASTNVP-----
Mvan_3689|M.vanbaalenii_PYR-1 QLMADMMHSSDSGAADTLWERYSGPDNMAFNRNFATYGLTSLQPQPGFSS
Mflv_2833|M.gilvum_PYR-GCK QLMANMMHSSDSDAADTLWERYSGPDNMAFNRNFATYGLTSLQPQQGFSG
: *::***..**: :* . .* ... *** .
MSMEG_6822|M.smegmatis_MC2_155 YNGHWDVTQSTAADLVHYYDMLLNGGGGLPREQADVIVDNLAHFTPSGTD
TH_1402|M.thermoresistible__bu YNGHWDVTLSTANDLIRYYDKLLDGSGGLPREQAAIIIDNIARFTPSGVD
Mb2929|M.bovis_AF2122/97 SDGRWWNTISSAPDLIRYYDMLLDGSGGLPLDRAAVIIADLAQSTPTGID
Rv2905|M.tuberculosis_H37Rv SDGRWWNTISSAPDLIRYYDMLLDGSGGLPLDRAAVIIADLAQSTPTGID
MMAR_1803|M.marinum_M SDGRWWNTFSSAPDLIRYYEMLLDGEGGLPLQSAAIIVNDLAQSTPNGID
MUL_2051|M.ulcerans_Agy99 SDGRWWNTFSSAPDLIRYYEMLLDGEGGLPLQSAAIIVNDLAQSTPNGID
MAV_3761|M.avium_104 GDGRWWNTMSSVTDLIRYYDMLLDGSGGLPADQARIIVSDLAQSTPNGVD
MAB_3225|M.abscessus_ATCC_1997 SDGMWWNTISTANDLVQYYDMLLSGTGGLPPERANIIVDDLSRSTPNGID
Mvan_3689|M.vanbaalenii_PYR-1 THPYWGFQKATSEDLDRLMNYTLTS---LPAAETAAIVSEMQHLDAN---
Mflv_2833|M.gilvum_PYR-GCK TYPYWGFQKATSEDLDRLMNYTLTS---LPAAQTAAIVSEMQHLDAN---
* :: ** : : * . ** : *: :: : ..
MSMEG_6822|M.smegmatis_MC2_155 GYPQRFGIPDGLSGEAVAVKQGWFCCWNRANQLHVSTGIIGPDHRYLMAI
TH_1402|M.thermoresistible__bu GYPQRFGIPDGLHGERVAVKQGWFCCWNGANQLHVSSGTIGPDHRYVMVI
Mb2929|M.bovis_AF2122/97 GYPQRFGIPDGLYAEPVAVKQGWMCCIG-SSWMHLSTGVIGPERRYIMVI
Rv2905|M.tuberculosis_H37Rv GYPQRFGIPDGLYAEPVAVKQGWMCCIG-SSWMHLSTGVIGPERRYIMVI
MMAR_1803|M.marinum_M GYPQRFGIPDGLYAEPVAVKQGWMCCIG-ADWMHLSTGIIGSDRRYIMVI
MUL_2051|M.ulcerans_Agy99 GYPQRFGIPDGLYAEPVAVKQGWMCCIG-ADWMHLSTGIIGSDRRYIIVI
MAV_3761|M.avium_104 GYPQRFGIPDGLYAEPVAVKQGWMCCIG-ADWMHLSTGVIGADRRYIMVV
MAB_3225|M.abscessus_ATCC_1997 GYPQRFGIPDGIPGEPVAVKQGWMCCVG-SAWMHLSTGVVGPDRRFIVVV
Mvan_3689|M.vanbaalenii_PYR-1 ---QQWGVWGAGAAMTPGNKNGWSQEQG--GWVVNSVGFAGPRQRYTLAI
Mflv_2833|M.gilvum_PYR-GCK ---QQWGVWGAGAAMTPGNKNGWSQEQG--GWVVNSVGFAGPRQRYTLAI
*::*: .. . . *:** . : * * *. :*: :.:
MSMEG_6822|M.smegmatis_MC2_155 SSLDPTSAGAAR--ENITEAVRTMFPGGKI-------
TH_1402|M.thermoresistible__bu SSLDPTSEAAAR--ENITRAVKTVFPEGRI-------
Mb2929|M.bovis_AF2122/97 ESLQPADDATAR--ATITQAVRTMFPNGRI-------
Rv2905|M.tuberculosis_H37Rv ESLQPADDATAR--ATITQAVRTMFPNGRI-------
MMAR_1803|M.marinum_M ESLQASDDATAR--ETITQAVKTIFPAGRI-------
MUL_2051|M.ulcerans_Agy99 ESLQASDDATAR--ETITQAVKTIFPAGRI-------
MAV_3761|M.avium_104 QSLQPADDATAR--ETITRAVKTIFPDGRIEAPPHGL
MAB_3225|M.abscessus_ATCC_1997 SSLQTANDVTAR--NTLTQAVATMFPGGRIETE----
Mvan_3689|M.vanbaalenii_PYR-1 MNSLNGEGGYDDGVETTTRLARILLAPA---------
Mflv_2833|M.gilvum_PYR-GCK MNSLNGEGAYDDGVETTTRLAQILLAPA---------
. . . *. . ::. .