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M. smegmatis MC2 155 MSMEG_6822 (-)

annotation: beta-lactamase
coordinates: 6872926 - 6873837
length: 303

MRRRQPKSVMTGMAVVACAALLVSGCTAPAGGAPPAVEHTPQATVAPPAAPPPVQPPASFAGLDARMQQA
TADAAASGATIEAVVLDRNTGEVVSNGSNKPFPIASVVKLFIADDLLLQESEGKTELSPADRKSLDVMLR
SSDDSAAQMFWDRLGGNAVISRIKARYGLPGTIAPYNGHWDVTQSTAADLVHYYDMLLNGGGGLPREQAD
VIVDNLAHFTPSGTDGYPQRFGIPDGLSGEAVAVKQGWFCCWNRANQLHVSTGIIGPDHRYLMAISSLDP
TSAGAARENITEAVRTMFPGGKI
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_6822--100% (303)beta-lactamase
M. smegmatis MC2 155MSMEG_2439-3e-9157.01% (314) LppW protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2929lppW2e-8350.95% (316) alanine rich lipoprotein LppW
M. gilvum PYR-GCKMflv_0952-1e-11168.64% (287) beta-lactamase
M. tuberculosis H37RvRv2905lppW2e-8350.95% (316) alanine rich lipoprotein LppW
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_3225-7e-8554.18% (299) putative lipoprotein LppW precursor
M. marinum MMMAR_1803lppW9e-8049.22% (319) alanine rich lipoprotein LppW
M. avium 104MAV_3761-4e-8054.44% (270) LppW protein
M. thermoresistible (build 8)TH_1402lppW1e-10778.72% (235) PROBABLE CONSERVED ALANINE RICH LIPOPROTEIN LPPW
M. ulcerans Agy99MUL_2051lppW2e-7948.90% (319) alanine rich lipoprotein LppW
M. vanbaalenii PYR-1Mvan_5916-1e-12973.87% (310) beta-lactamase

CLUSTAL 2.0.9 multiple sequence alignment


Mb2929|M.bovis_AF2122/97            MRARPLTLLTALAAVTLVV---VAGCEARVEAEAYSAADRISSRPQARPQ
Rv2905|M.tuberculosis_H37Rv         MRARPLTLLTALAAVTLVV---VAGCEARVEAEAYSAADRISSRPQARPQ
MMAR_1803|M.marinum_M               MRARPLTMLTAAAAVALVVSLVLTGCEAKVQAKAYGTDDRESSRQQSQPQ
MUL_2051|M.ulcerans_Agy99           MRARPLTMLTAAAAVALVVSLVLTGCEAKVQAKAYGTDDRESSRQQSQPQ
MAV_3761|M.avium_104                MRVRPLTLFTATAAVTLLI---AAGSEALVQAKVYHLPVAAPVRVLTQPP
MSMEG_6822|M.smegmatis_MC2_155      MRRRQPKSVMTGMAVVACAALLVSGCTAPAGG----------APPAVEHT
Mvan_5916|M.vanbaalenii_PYR-1       MRRRRRLNRAKVATAIVSVALLVNGCEARVFG----------TPPAAENT
TH_1402|M.thermoresistible__bu      --------------------------------------------LSTTST
Mflv_0952|M.gilvum_PYR-GCK          --------MAIATMAAACAALLVSGCTAQVSG----------MPPDSQIP
MAB_3225|M.abscessus_ATCC_1997      MRGQHLFVGLTLTAATALTSGCVASVRS---------------------D
                                                                                      

Mb2929|M.bovis_AF2122/97            PQ-PVELLLRAITPPRAPAAS-PNVGFGELPTRVRQATDEAAAMGATLSV
Rv2905|M.tuberculosis_H37Rv         PQ-PVELLLRAITPPRAPAAS-PNVGFGELPTRVRQATDEAAAMGATLSV
MMAR_1803|M.marinum_M               QQQLIELLLRAITPPEDPAALLPSAGLVGVQERIQRATEEAAAKGATITV
MUL_2051|M.ulcerans_Agy99           QQQLIELLLRAITPPEDPAALLPSAGLVGVQERIQRATEEAAAKGATITV
MAV_3761|M.avium_104                PPQSAALMLEAATPPQPPQAL-PNAGFAQLPARIQQAADQAAASGAALSV
MSMEG_6822|M.smegmatis_MC2_155      PQATVAPPAA-------PPPVQPPASFAGLDARMQQATADAAASGATIEA
Mvan_5916|M.vanbaalenii_PYR-1       PQAPVVAPQASLPALPEAPPNQPTEPLAGLDARVRQATADAAASGADIET
TH_1402|M.thermoresistible__bu      PX---------------------------------QATADAAASGADITI
Mflv_0952|M.gilvum_PYR-GCK          PQAPVTQVP-------EAPPAHPALSFDGLDARVKQAAAQAAESGAELTA
MAB_3225|M.abscessus_ATCC_1997      PATPVLAVVSAPAETPPVFEVESPTSFETLPERTTAATTQAKSAGATLTA
                                                                        *: :*   ** :  

Mb2929|M.bovis_AF2122/97            AVLDRATGQLVSNGNTQIIATASVAKLFIADDLLLAEAEGKVTLSPEDHH
Rv2905|M.tuberculosis_H37Rv         AVLDRATGQLVSNGNTQIIATASVAKLFIADDLLLAEAEGKVTLSPEDHH
MMAR_1803|M.marinum_M               AILDRATHQLVSNGKTSIIATASVSKLFIADELLLRASQGKTTLSAQDRQ
MUL_2051|M.ulcerans_Agy99           AILDRATHQLVSNGKTSIIATASVSKLFIADELLLRASQGKTTLSAQDRQ
MAV_3761|M.avium_104                AILDRGTHQLVSIGNGQIVGTASVAKLFIADDLLLHQAEGKAALSADDRQ
MSMEG_6822|M.smegmatis_MC2_155      VVLDRNTGEVVSNGSNKPFPIASVVKLFIADDLLLQESEGKTELSPADRK
Mvan_5916|M.vanbaalenii_PYR-1       VVLDRNTGQIISNGANKPFPIASVVKLFIADDLLLQESEGKTQLSAADRK
TH_1402|M.thermoresistible__bu      AVLDRSTGQAASSGGDTPFPIASVVKLFIADDLLLQESEGKTQLSDADRA
Mflv_0952|M.gilvum_PYR-GCK          AVLDRDTGGFVSVGAGTPFPIASVVKLFIADDVLLRESRGEMELSAADRD
MAB_3225|M.abscessus_ATCC_1997      VIKDRASGAVVSNGNNSTIAIASVAKLFIADDLLMRESQGEVTLTPADRA
                                    .: ** :    * *    .  *** ******::*:  :.*:  *:  *: 

Mb2929|M.bovis_AF2122/97            ALDVMLQSSDDGAAERFWSQDGGNAVVTQVARRYGLRSTAPPSDGRWWNT
Rv2905|M.tuberculosis_H37Rv         ALDVMLQSSDDGAAERFWSQDGGNAVVTQVARRYGLRSTAPPSDGRWWNT
MMAR_1803|M.marinum_M               ALDNMLRSSDDGAAEQFWGELGGDAIVTEIATRYGLAATAPPSDGRWWNT
MUL_2051|M.ulcerans_Agy99           ALDNMLRSSDDGAAEQFWGELGGDAIVTEIATRYGLAATAPPSDGRWWNT
MAV_3761|M.avium_104                ALDIMLQSSDDGAAERFWGQGGGAAIISEVASRYGLTSTTPPGDGRWWNT
MSMEG_6822|M.smegmatis_MC2_155      SLDVMLRSSDDSAAQMFWDRLGGNAVISRIKARYGLPGTIAPYNGHWDVT
Mvan_5916|M.vanbaalenii_PYR-1       SLDVMLRSSDDSAAQIFWDRSGQNAVIARVVARYGLTGTTAPHNGHWDVT
TH_1402|M.thermoresistible__bu      ALDLMLRSSDDGAAQMFWDRNGGNAVISRIVARYGLTGTTPPYNGHWDVT
Mflv_0952|M.gilvum_PYR-GCK          SLGVMLRSSDDSAAQTFWDRSGGNAVIARTVSRYGLGGTTAPSNGRWDVT
MAB_3225|M.abscessus_ATCC_1997      AFDRMLQSSDDSAAEVFWQRGGGNSIITRVAARYGLASTNVPSDGMWWNT
                                    ::. **:****.**: ** . *  ::::.   **** .*  * :* *  *

Mb2929|M.bovis_AF2122/97            ISSAPDLIRYYDMLLDGSGGLPLDRAAVIIADLAQSTPTGIDGYPQRFGI
Rv2905|M.tuberculosis_H37Rv         ISSAPDLIRYYDMLLDGSGGLPLDRAAVIIADLAQSTPTGIDGYPQRFGI
MMAR_1803|M.marinum_M               FSSAPDLIRYYEMLLDGEGGLPLQSAAIIVNDLAQSTPNGIDGYPQRFGI
MUL_2051|M.ulcerans_Agy99           FSSAPDLIRYYEMLLDGEGGLPLQSAAIIVNDLAQSTPNGIDGYPQRFGI
MAV_3761|M.avium_104                MSSVTDLIRYYDMLLDGSGGLPADQARIIVSDLAQSTPNGVDGYPQRFGI
MSMEG_6822|M.smegmatis_MC2_155      QSTAADLVHYYDMLLNGGGGLPREQADVIVDNLAHFTPSGTDGYPQRFGI
Mvan_5916|M.vanbaalenii_PYR-1       TSTASDLVRYYDMLLDGSGGLPREQADIIIGNLARFTPTGVDGYPQRFGI
TH_1402|M.thermoresistible__bu      LSTANDLIRYYDKLLDGSGGLPREQAAIIIDNIARFTPSGVDGYPQRFGI
Mflv_0952|M.gilvum_PYR-GCK          LSTSGDLVRYYDMLLDGAGGLPPEQTEFIVGNLARSTPTGTDGYPQRFGI
MAB_3225|M.abscessus_ATCC_1997      ISTANDLVQYYDMLLSGTGGLPPERANIIVDDLSRSTPNGIDGYPQRFGI
                                     *:  **::**: **.* **** : : .*: :::: **.* *********

Mb2929|M.bovis_AF2122/97            PDGLYAEPVAVKQGWMCCIG-SSWMHLSTGVIGPERRYIMVIESLQPADD
Rv2905|M.tuberculosis_H37Rv         PDGLYAEPVAVKQGWMCCIG-SSWMHLSTGVIGPERRYIMVIESLQPADD
MMAR_1803|M.marinum_M               PDGLYAEPVAVKQGWMCCIG-ADWMHLSTGIIGSDRRYIMVIESLQASDD
MUL_2051|M.ulcerans_Agy99           PDGLYAEPVAVKQGWMCCIG-ADWMHLSTGIIGSDRRYIIVIESLQASDD
MAV_3761|M.avium_104                PDGLYAEPVAVKQGWMCCIG-ADWMHLSTGVIGADRRYIMVVQSLQPADD
MSMEG_6822|M.smegmatis_MC2_155      PDGLSGEAVAVKQGWFCCWNRANQLHVSTGIIGPDHRYLMAISSLDPTSA
Mvan_5916|M.vanbaalenii_PYR-1       PDGLNAEPVAVKQGWFCCWNGGNQLHVSTGIIGPDRRYVMAISSLDPTGD
TH_1402|M.thermoresistible__bu      PDGLHGERVAVKQGWFCCWNGANQLHVSSGTIGPDHRYVMVISSLDPTSE
Mflv_0952|M.gilvum_PYR-GCK          PDGLRGEPVAVKQGWFCCWNGGNHLHVSTGVVGADRRYVVALSSLDPSGE
MAB_3225|M.abscessus_ATCC_1997      PDGIPGEPVAVKQGWMCCVG-SAWMHLSTGVVGPDRRFIVVVSSLQTAND
                                    ***: .* *******:** . .  :*:*:* :*.::*:::.:.**:.:. 

Mb2929|M.bovis_AF2122/97            ATARATITQAVRTMFPNGRI-------
Rv2905|M.tuberculosis_H37Rv         ATARATITQAVRTMFPNGRI-------
MMAR_1803|M.marinum_M               ATARETITQAVKTIFPAGRI-------
MUL_2051|M.ulcerans_Agy99           ATARETITQAVKTIFPAGRI-------
MAV_3761|M.avium_104                ATARETITRAVKTIFPDGRIEAPPHGL
MSMEG_6822|M.smegmatis_MC2_155      GAARENITEAVRTMFPGGKI-------
Mvan_5916|M.vanbaalenii_PYR-1       AAARENITRAVRTMFPGGKI-------
TH_1402|M.thermoresistible__bu      AAARENITRAVKTVFPEGRI-------
Mflv_0952|M.gilvum_PYR-GCK          AAARQNMTRAVETMFPGGSI-------
MAB_3225|M.abscessus_ATCC_1997      VTARNTLTQAVATMFPGGRIETE----
                                     :** .:*.** *:** * *