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VSMPSDSVVAVAGSSGLIGTALVYALRATDHRVIRIVRRAPSNADEVFWNPDTGEFDADALHDVDAVVNL CGVNVGQKRWSGAFKQSLRDSRIGPTEVLARAVVDAGVPVLVNASAVGYYGDTGGTPVDETAGPGHNFLA RLAVDWEAATIVAARAGVRVVLTRTGLVMARAGGMLSRLRPLFSLGLGARLGNGRQYLSWISLEDQVRAL LFAISHDEMIGPVNMTGPAPVTNAEFTTALGRSVNRPTPLVVPGFALRLALGEFADEGVLGGQRAIPAAL ERAGFQFHHNTIGEALAFATAPNGE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3580 | - | - | 100% (305) | hypothetical protein Mvan_3580 |
| M. vanbaalenii PYR-1 | Mvan_3512 | - | 4e-61 | 47.28% (294) | hypothetical protein Mvan_3512 |
| M. vanbaalenii PYR-1 | Mvan_0427 | - | 1e-06 | 27.44% (266) | NAD-dependent epimerase/dehydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2239 | - | 1e-122 | 71.33% (300) | hypothetical protein Mb2239 |
| M. gilvum PYR-GCK | Mflv_2934 | - | 1e-155 | 89.84% (305) | hypothetical protein Mflv_2934 |
| M. tuberculosis H37Rv | Rv2216 | - | 1e-122 | 71.33% (300) | hypothetical protein Rv2216 |
| M. leprae Br4923 | MLBr_00860 | - | 1e-123 | 71.43% (294) | hypothetical protein MLBr_00860 |
| M. abscessus ATCC 19977 | MAB_1944c | - | 1e-105 | 63.23% (291) | hypothetical protein MAB_1944c |
| M. marinum M | MMAR_3261 | - | 1e-125 | 73.90% (295) | hypothetical protein MMAR_3261 |
| M. avium 104 | MAV_2272 | - | 1e-123 | 73.56% (295) | hypothetical protein MAV_2272 |
| M. smegmatis MC2 155 | MSMEG_4284 | - | 1e-124 | 72.15% (298) | hypothetical protein MSMEG_4284 |
| M. thermoresistible (build 8) | TH_0221 | - | 1e-124 | 73.56% (295) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_3576 | - | 1e-124 | 73.47% (294) | hypothetical protein MUL_3576 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3580|M.vanbaalenii_PYR-1 MSMPS-DSVVAVAGSSGLIGTALVYALRATDHRVIRIVRRAPSNADEVFW
Mflv_2934|M.gilvum_PYR-GCK MSMRS-DSVVAIAGSSGLIGTALVYALRATDHRVIRIVRRAPSNADEVFW
MMAR_3261|M.marinum_M MGK----AVVAIAGSSGLIGSALAAALRAADHRVLRIVRRTPANSEELHW
MUL_3576|M.ulcerans_Agy99 MGK----AVVAIAGSSGLIGSALAAALRAADHRVLRIVRRTPANSEELHW
Mb2239|M.bovis_AF2122/97 MAN----AVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHW
Rv2216|M.tuberculosis_H37Rv MAN----AVVAIAGSSGLIGSALTAALRAADHTVLRIVRRAPANSEELHW
MLBr_00860|M.leprae_Br4923 MAQASRKAVVAIAGSSGMIGSALAAALRANDHLVLRIVRRTPANAEELHW
MAV_2272|M.avium_104 MARAGQKAVIAIAGSSGLIGSALAAALRADDHRVLRIVRRAPANGDELSW
TH_0221|M.thermoresistible__bu ------MAVIAIAGSSGLIGSALVYALRAADHRVLRIVRRAPANPDELFW
MSMEG_4284|M.smegmatis_MC2_155 MAD----AVIAIAGSSGLIGSALTSALRADGHRVLRLVRRAPSNPDELFW
MAB_1944c|M.abscessus_ATCC_199 MGAESQHKRIVIAGSSGVIGSALVASLRSANHTVVRLVRRDPMGPDERRW
:.:*****:**:**. :**: .* *:*:*** * . :* *
Mvan_3580|M.vanbaalenii_PYR-1 NPDTGEFDADALHDVDAVVNLCGVNVGQKRWSGAFKQSLRDSRIGPTEVL
Mflv_2934|M.gilvum_PYR-GCK NPDTGEFDATALDGVDAVVNLCGVNVGQKRWSGAFKQSLRDSRIGPTEVL
MMAR_3261|M.marinum_M NPESGEFDPDALTDVDVVINLCGVGIGRRRWSGAFKQSLRDSRITPTEVL
MUL_3576|M.ulcerans_Agy99 NPESGEFDPDALTDVDVVINLCGVGIGRRRWSGAFKQSLRDSRITPTEVL
Mb2239|M.bovis_AF2122/97 NPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVL
Rv2216|M.tuberculosis_H37Rv NPESGEFDPHALTDVDAVVNLCGVNIAQRRWSGAFKQSLRDSRITPTEVL
MLBr_00860|M.leprae_Br4923 NPESGEFDTDAITDVDAVVNLCGVNLGQRRWSGSFKQNLRDSRITPTEVL
MAV_2272|M.avium_104 NPESGDLDPDALRGVDAVVNLCGVNIGKRRWSGAFKQSLRDSRITPTEVL
TH_0221|M.thermoresistible__bu NPDSGEFDADRLRGVDAVVNLCGVNIGARRWSGSFKQQLRDSRITPTEVL
MSMEG_4284|M.smegmatis_MC2_155 NPDTGEFDATALHGVDVVVNLCGVNLGDKRWSGAFKQSLRDSRIGPTEVL
MAB_1944c|M.abscessus_ATCC_199 DPASGQIEPGGLDGADAVVNMCGVGVGDKRWSGAYKQEIYDSRVIPTEVL
:* :*:::. : ..*.*:*:***.:. :****::**.: ***: *****
Mvan_3580|M.vanbaalenii_PYR-1 ARAVVDAGVPVLVNASAVGYYGDTGGTPVDETAGPGHNFLARLAVDWEAA
Mflv_2934|M.gilvum_PYR-GCK ANAVVEAQVPVLVNASAVGFYGDTGSTPVDETAGPGQNFLARLAIDWEAA
MMAR_3261|M.marinum_M SSAVADAGVPTLINASAVGYYGDTRDRVVDENDPAGMGFLAQLCVDWEAA
MUL_3576|M.ulcerans_Agy99 SSAVADAGVPTLINASAVGYYGDTRDRVVDENDPAGMGFLAQLCVDWEAA
Mb2239|M.bovis_AF2122/97 SAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETA
Rv2216|M.tuberculosis_H37Rv SAAVADAGVATLINASAVGYYGNTKDRVVDENDSAGTGFLAQLCVDWETA
MLBr_00860|M.leprae_Br4923 SAAVAEAGVKTFINASAVGYYGNTRDRVVDENDRAGTGFLAQLCQDWEGA
MAV_2272|M.avium_104 AHAVADAGVATLVNASAVGFYGNTKDRVVDENDRAGTGFLAQLCQDWEAA
TH_0221|M.thermoresistible__bu TAAVVEAGVPVLVNASAVGVYGDTRDRAVDESAPPGQGFLARLCQDWEAA
MSMEG_4284|M.smegmatis_MC2_155 SAAVADAGVPVLINASAVGFYGDTRDRITDESAPAGQGFLATLCQDWEAA
MAB_1944c|M.abscessus_ATCC_199 ARAVAEAGVPVLINASAVGYYGDSGDRIIDETASSGTSFLARVCLDWEAA
: **.:* * .::****** **:: . **. .* .*** :. *** *
Mvan_3580|M.vanbaalenii_PYR-1 TIVAARAGVRVVLTRTGLVMARAGGMLSRLRPLFSLGLGARLGNGRQYLS
Mflv_2934|M.gilvum_PYR-GCK TTVASQSGVRVVLTRTGLVMAPSGGMLSRLRLLFSLGLGARLGNGRQYLS
MMAR_3261|M.marinum_M TLPAQYAGTRVVLARTGLVLAPAGGTLRPLRPAFSVGLGARLGSGRQYMA
MUL_3576|M.ulcerans_Agy99 TLPAQYAGTRVVLARTGLVLAPAGGTLRPLRPAFSVGLGARLGSGRQYMA
Mb2239|M.bovis_AF2122/97 TRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMS
Rv2216|M.tuberculosis_H37Rv TRPAQQSGARVVLARTGVVLSPAGGMLRRMRPLFSVGLGARLGSGRQYMS
MLBr_00860|M.leprae_Br4923 TLPAQYAGTRVILARTGMVLAQEAGVLSRMRPLFSFALGARIGNGRQYMS
MAV_2272|M.avium_104 TLPAQYGGARVVLARTGLVFSPAGGALGRLRPLFRTGLGARLGSGRQYMS
TH_0221|M.thermoresistible__bu TTPARQAGVRVVLARTGLVVSPSGGLLSRLRPLFAAGLGARLGSGCQYMS
MSMEG_4284|M.smegmatis_MC2_155 TAQAVAAGTRVVLLRTGLVLARSGGLIGRLKPLFSFGLGARLGNGRQYMP
MAB_1944c|M.abscessus_ATCC_199 TAEAAQAGARVVIVRTGLVLSPAGGLFGRSRPLFSLGLGARLGNGRWYMP
* * .*.**:: ***:*.: .* : : * .****:*.* *:.
Mvan_3580|M.vanbaalenii_PYR-1 WISLEDQVRALLFAISHDEMIGPVNMTGPAPVTNAEFTTALGRSVNRPTP
Mflv_2934|M.gilvum_PYR-GCK WISLEDQVRALLFAISHHELAGPVNVTGPAPVTNAEFTTALGRALNRPTP
MMAR_3261|M.marinum_M WISLEDEVRALLFAISNPTLSGPVNMAGPAPVTNAEFTTAFGRALNRPTP
MUL_3576|M.ulcerans_Agy99 WISLEDEVRALLFAISNPTLSGPVNMAGPAPVTNAEFTTAFGRALNRPTP
Mb2239|M.bovis_AF2122/97 WISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRAVNRPTP
Rv2216|M.tuberculosis_H37Rv WISLEDEVRALQFAIAQPNLSGPVNLTGPAPVTNAEFTTAFGRAVNRPTP
MLBr_00860|M.leprae_Br4923 WISLEDEVRALLFAISHQSLSGPLNLTGPAPVTNAEFTTAFGRAINRPTP
MAV_2272|M.avium_104 WITLEDEVRALLFAIFEPALSGPVNMTGPAPVTNAEFTTAFGRAVNRPTP
TH_0221|M.thermoresistible__bu WISLEDEVRALQRLLTDDALSGPVNLTGPAPVTNAEFTAALGRALNRPAP
MSMEG_4284|M.smegmatis_MC2_155 WISLDDHIRAVRFTMDNDTMSGPVNVTGPAPVTNAEFTSVLGRTLGRPTP
MAB_1944c|M.abscessus_ATCC_199 WISLEDHIRALEFALAEPAVSGPVNLTGPAPVTNAEFTAALGRVLHRPTL
**:*:*.:**: : . : **:*::***********:.:** : **:
Mvan_3580|M.vanbaalenii_PYR-1 LVVPGFALRLALGEFADEGVLGGQRAIPAALERAGFQFHHNTIGEALAFA
Mflv_2934|M.gilvum_PYR-GCK LAVPGFVLRAALGEFADEGVLGGQRAIPAALERAGFQFHHHTIGEALAFA
MMAR_3261|M.marinum_M LMLPGFAARAALGEFADEGLLIGQRAIPTALEQAGFQFHHNTIGEALSYA
MUL_3576|M.ulcerans_Agy99 LMLPGFAARAVLGEFADEGLLIGQRAIPTALEQAGFQFHHNTIGEALSYA
Mb2239|M.bovis_AF2122/97 LMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYA
Rv2216|M.tuberculosis_H37Rv LMLPSVAVRAAFGEFADEGLLIGQRAIPSALERAGFQFHHNTIGEALGYA
MLBr_00860|M.leprae_Br4923 LMLPSFAVRAALGEFADEGLLIGQRAIPAALERAGFQFHHNTIGEALSYA
MAV_2272|M.avium_104 LMLPGFAVRAALGEFADEGLLTGQRAIPAALERTGFVFHHNTIGEALGYA
TH_0221|M.thermoresistible__bu WVLPGVAVRALLGEFAEEGVLAGQRVVPAALEAAGFGFRHNTIGAALAYA
MSMEG_4284|M.smegmatis_MC2_155 LFVPAVALRTLLGEFADEGLLAGQRAIPAALEIKGFEFHHKTVREALAHV
MAB_1944c|M.abscessus_ATCC_199 LVAPQFALSLIFGEFADAELTSSMRVIPAVLEQHGFEFEHHTIGEALAYA
* .. :****: : . *.:*:.** ** *.*:*: **...
Mvan_3580|M.vanbaalenii_PYR-1 TAPNGE-
Mflv_2934|M.gilvum_PYR-GCK TAPQRE-
MMAR_3261|M.marinum_M TARRDQI
MUL_3576|M.ulcerans_Agy99 TERRDQI
Mb2239|M.bovis_AF2122/97 TTRPG--
Rv2216|M.tuberculosis_H37Rv TTRPG--
MLBr_00860|M.leprae_Br4923 TTRPSQN
MAV_2272|M.avium_104 TARPAHD
TH_0221|M.thermoresistible__bu TAGPDAR
MSMEG_4284|M.smegmatis_MC2_155 TAPKEP-
MAB_1944c|M.abscessus_ATCC_199 NNSRPMK
.