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LRRLTAAAAALLLLAGCGTDSSAPEDTSTSSAPETAAAVSPEEARAIAKEAYVYGFPMVDNYRVQYSYFV DKQDPEYKGGWNEVHNTARVYTPEDTAIQTPNSDTPYSFVGADLRAEPLVLTVPPVQQDRYYSLQFVDGY TYNFAYVGSRTAGNGGGRYLLAGPGWQGEKPEGIDEVIRSDTELAFVLYRTQLFGPSDIEEVRKIQAGYQ AAPLSVYLNRPPPPPAPAIDFVPPLTPEQQRTSPQFFEILNFVMRFAPALPEETALRERFARIGIGPDGD FDADSLSPQMRAAIEGGMADGNAELDAFKKNEMDTGNVTSAQLFGSRQELGDNYLFRMAGAAYGIYGNTA AEAIYPNFSNDAAGQPLTGANRYVFRFPSGGLPPVNAFWSLTMYELPASLLVENPINRYLINSAMLPSVV PDPDGGYTFYIQNESPGIDKEANWLPAPKGPFALVLRLYWPKPDALNGSWRSPQPERV*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3476 | - | - | 100% (479) | hypothetical protein Mvan_3476 |
| M. vanbaalenii PYR-1 | Mvan_2722 | - | 6e-13 | 33.33% (159) | hypothetical protein Mvan_2722 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3051 | - | 0.0 | 79.17% (480) | hypothetical protein Mflv_3051 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3998 | - | 1e-68 | 34.45% (479) | hypothetical protein MAB_3998 |
| M. marinum M | MMAR_2611 | - | 7e-51 | 32.51% (443) | hypothetical protein MMAR_2611 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4187 | - | 0.0 | 72.81% (467) | hypothetical protein MSMEG_4187 |
| M. thermoresistible (build 8) | TH_3203 | - | 3e-55 | 35.31% (405) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3150 | - | 8e-52 | 32.89% (447) | hypothetical protein MUL_3150 |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3998|M.abscessus_ATCC_1997 -----------MKIWCTQWTKLLVVMSTVALATGLTSCSKEPGSQKLSAD
TH_3203|M.thermoresistible__bu --------------------------------------------------
MMAR_2611|M.marinum_M -------------------------MSTLSSG------------------
MUL_3150|M.ulcerans_Agy99 -------------------------MSTLSSG------------------
Mvan_3476|M.vanbaalenii_PYR-1 -----MLRRLTAAAAALLLLAGCG-TDSSAP-EDTSTSSAPETAAAVSPE
Mflv_3051|M.gilvum_PYR-GCK -----MLRRSIAALAALVLLVGCS-TDSSSQQADTSTSSPSETAAAVTPA
MSMEG_4187|M.smegmatis_MC2_155 MRQTGSLRPILVPVWILVLVAALAGCATRTDDQPTESAPPPAQQAPPTPA
MAB_3998|M.abscessus_ATCC_1997 EAKSIAMDAYVYGYALVTMEMTRRVMTNVEKAEPPRA-PMGQLMRMREYP
TH_3203|M.thermoresistible__bu ---------------------------------------MNQLAHLGFLP
MMAR_2611|M.marinum_M -LRTLSYEAFIYFYPLVMMDVTRLQALNAAPGTGPGAGPPNHFSHMRAFP
MUL_3150|M.ulcerans_Agy99 -LRTLSYEAFIYFYPLVMMDVTRLQALNAAPSTGPGAGPPNHFSHMRAFP
Mvan_3476|M.vanbaalenii_PYR-1 EARAIAKEAYVYGFPMVDN-YRVQYSYFVDKQDPEYKGGWNEVHNTARVY
Mflv_3051|M.gilvum_PYR-GCK EARAIAKDAYVYGFPLVDN-YRVQYSYFVDKEDPEYKGGWNQIHNTARLY
MSMEG_4187|M.smegmatis_MC2_155 EIRAIAKDAYIWGFPLVDN-YRVQYSYFVDKTDPEYKGGFNEVHNTARLY
... .
MAB_3998|M.abscessus_ATCC_1997 NAAFRDVTAPNADTLYTNGFIDVGKEPWILSLPEAD-GRYYLFPMLDGFT
TH_3203|M.thermoresistible__bu TAEFTGVVRPNVDTLYTSMFFDVSAEPLIVTVPPMG-DRYHLFPLLDMWT
MMAR_2611|M.marinum_M SADFRAVVRPNFDTLYSSAWLDLRNGPVRLQSADTD-DRYYMLPMLDMWT
MUL_3150|M.ulcerans_Agy99 SADFRAVVRPNFDTLYSSAWLDLRNGPVRLQSADTD-DRYYMLPMLDMWT
Mvan_3476|M.vanbaalenii_PYR-1 TPEDTAIQTPNSDTPYSFVGADLRAEPLVLTVPPVQQDRYYSLQFVDGYT
Mflv_3051|M.gilvum_PYR-GCK TPEDKAIQTPNSDTPYSFVGADLRTEPLVLTVPPIQQDRYYSLQFIDGYT
MSMEG_4187|M.smegmatis_MC2_155 TPADKAIQTPNADTPYSFVGADLRTEPLVFTVPPIEQNRYFSLQFVDGYT
.. : ** ** *: *: * . . .**. : ::* :*
MAB_3998|M.abscessus_ATCC_1997 NVFEVPGKRTTGTG--PQTYAITGPGWKG------TLPQGVQEYK-SPTA
TH_3203|M.thermoresistible__bu NVDASPGTRTVDDAGTGYEFAIVGPNWHG------DLPEGVREYR-SATD
MMAR_2611|M.marinum_M DVFANPGKRTSGTG--PLDLVIAGPGYQGESGE---QPRPTTVVA-APTP
MUL_3150|M.ulcerans_Agy99 DVFANPGKRTSGTG--PLDLVIAGPGYQGESGESGEQPRPTTVVA-APTP
Mvan_3476|M.vanbaalenii_PYR-1 YNFAYVGSRTAGNG--GGRYLLAGPGWQG------EKPEGIDEVIRSDTE
Mflv_3051|M.gilvum_PYR-GCK YNFAYVGSRTTGNG--GGTYLLAGPGWQG------EKPEGVDEVIRSDTE
MSMEG_4187|M.smegmatis_MC2_155 YNVAYVGSRTTGNG--GGRYLLAGPGWEG------EKPEGVDEIIRSDTD
*.** . . :.**.:.* *. : *
MAB_3998|M.abscessus_ATCC_1997 LVWLLGRIYCTGTPEDYAAVHTLQDAISLVPLSSYGKPYTP-AAGHVDPS
TH_3203|M.thermoresistible__bu AGWMIGRIQVNG-PEDMPAVIDLQNAMTAVPLSAHGTPYEPPGNADLRPD
MMAR_2611|M.marinum_M FVWIIGRTQTNG-PADYPAVHRVQDGYSLTELGSG----AQASAGDKRPD
MUL_3150|M.ulcerans_Agy99 FVWIIGRTQTNG-PADYPAVHRVQDGYFLTELGSG----AQASAGDKRPD
Mvan_3476|M.vanbaalenii_PYR-1 LAFVLYRTQLFG-PSDIEEVRKIQAGYQAAPLSVYLNRPPPPPAPAIDFV
Mflv_3051|M.gilvum_PYR-GCK LAFVLYRTQLLG-PSDLDGVKDVQAGYQVAPLSVFLNQPSPEPAPAIDFV
MSMEG_4187|M.smegmatis_MC2_155 LAFVLYRTQLFG-PRDLDNIKKIQAGYQVAPLSVYLKQPSPPPAPPIDFT
::: * * * * : :* . . *.
MAB_3998|M.abscessus_ATCC_1997 IDMTTPVREQVNNLSTKAYFDLLATLLKDNPPAEADKPILEKMATIGIEP
TH_3203|M.thermoresistible__bu WPRGREVSRYIHDLSPQQYWDLFYSGLSHDQPRPGDEVLLERLAAVGWSP
MMAR_2611|M.marinum_M FDLTTEPPRIVNGMAALDYLSYAADLLCVNPPHPTDYSVLARLANLGIEA
MUL_3150|M.ulcerans_Agy99 FDLTTEPPRIVNGMAALDYLSYAADLLCVNSPHPTDYSVLARLANLGIEA
Mvan_3476|M.vanbaalenii_PYR-1 PPLTPE-----QQRTSPQFFEILNFVMRFAPALPEETALRERFARIGIGP
Mflv_3051|M.gilvum_PYR-GCK PPLTPD-----QQRTSPQFFEILNFALRYAPVLPQEQALRDRFATIGIGP
MSMEG_4187|M.smegmatis_MC2_155 PPLTPE-----AQKTSPQFFEILNAALRYAPVKPEEQEMRERFARIGIGP
:. : . : : : ::* :* .
MAB_3998|M.abscessus_ATCC_1997 GKPFDTDKLGTQTVSALESVPKEAFAKIMAH-FKEAGNNINGWVFT-TKT
TH_3203|M.thermoresistible__bu TEKLDLAQLPDDERDVWEQAWPQALSQIEVD-LGSE--EVNGWLLARTGL
MMAR_2611|M.marinum_M GSPFDASRFDADQVAELERGRSDALNDILKS-ATKLGANVDGWISLTESM
MUL_3150|M.ulcerans_Agy99 GSPFDASRFDADQVAELERGRSDALNDILKS-ATKLGANVDGWISLTESM
Mvan_3476|M.vanbaalenii_PYR-1 DGDFDADSLSPQMRAAIEGGMADGNAELDAFKKNEMDTGNVTSAQLFGSR
Mflv_3051|M.gilvum_PYR-GCK DGDYDADALTPEMRAAVEAGMADAWTEYDTFKKDKVETGEVTSAQFFGTR
MSMEG_4187|M.smegmatis_MC2_155 DGDFDADKLSPETREAIEDGMANAWVEFDRFKQDKVDTGEVGSAQLFGTA
* : : * :. . .
MAB_3998|M.abscessus_ATCC_1997 GQYGTDYLQRALITAIGLGANRPQDAVYPTSEVDNTGKPYDGANKYVLHF
TH_3203|M.thermoresistible__bu GDYGTDYATRAVVAHGGLGANLPSDAVYPTVRVDDTGAQLNAANDYVLRF
MMAR_2611|M.marinum_M GVYGNNYLRRAVVALIGLGANPAEDAVYPFLATDEHGDPLAGEHDYVIHF
MUL_3150|M.ulcerans_Agy99 GVYGNNYLRRAVVALIGLGANPAEDAVYPFLATDEHGDPLAGEHDYVIHF
Mvan_3476|M.vanbaalenii_PYR-1 QELGDNYLFRMAGAAYGIYGNTAAEAIYPNFSNDAAGQPLTGANRYVFRF
Mflv_3051|M.gilvum_PYR-GCK EDLKDNYLYRMAGAVLGIYGNTAAEAIYPAAFNDAAGAPLTGANNYVYRF
MSMEG_4187|M.smegmatis_MC2_155 DDLKGNYLYRMAGAVLGIYGNTAAEALYPSAMLDADGQPLTGTNSYTYRF
:* * : *: .* . :*:** * * . : *. :*
MAB_3998|M.abscessus_ATCC_1997 DKGQFPPAEGFWSLTMYDA-GMFFVDNPLGRYTLSQ--RNTFTPNPDGSV
TH_3203|M.thermoresistible__bu SPEDLPPVRGFWSLTLYDD-RGFFVDNPLDRYALR---GERLTTNPDGSV
MMAR_2611|M.marinum_M DADKLPPVDAFWSVTMYDA-EGFQVANELNRFAIGD--RDELRYNDDGSL
MUL_3150|M.ulcerans_Agy99 DADKLPPVDAFWSVTMYDA-EGFQVANELNRFAIGD--RDELRYNDDGSL
Mvan_3476|M.vanbaalenii_PYR-1 PSGGLPPVNAFWSLTMYELPASLLVENPINRYLINSAMLPSVVPDPDGGY
Mflv_3051|M.gilvum_PYR-GCK APGQLPPVNAFWSLTMYELPGSVLVANPMNRYLISSTMLPSLVRDPDGGY
MSMEG_4187|M.smegmatis_MC2_155 APDQLPPVNAFWSLTIYELPSSQLVDNPIDRYLINSEMLPSLVPDPDGAY
:**. .***:*:*: * * :.*: : . : **.
MAB_3998|M.abscessus_ATCC_1997 DLYLQHQNPGPEKEANWLPAP-TGKFNLMLRLYWPKETPPSIIDGTWKPP
TH_3203|M.thermoresistible__bu DVYVRHEPPGSDREANWLPTPETGDFNLMLRLYWP---EAEILDGGWNPP
MMAR_2611|M.marinum_M DLCLAHTDPGPERQSNWLPAP-LGPLGVTMRLYAP---RPEVVAGEWSPP
MUL_3150|M.ulcerans_Agy99 DLYLAHTDPGPERQSNWLPAP-LGPLGVTMRLYAP---RPEVVAGEWSPP
Mvan_3476|M.vanbaalenii_PYR-1 TFYIQNESPGIDKEANWLPAP-KGPFALVLRLYWP---KPDALNGSWRSP
Mflv_3051|M.gilvum_PYR-GCK TFTVQNASPGIEKESNWLPAP-KGPFGLVLRLYWP---KPDALNGTWTAP
MSMEG_4187|M.smegmatis_MC2_155 TLRIQNTQP-PENEANWLPAP-KGPFTLVLRLYWP---KPDALNGTWQAP
. : : * :.::****:* * : : :*** * .. : * * .*
MAB_3998|M.abscessus_ATCC_1997 AVQQVP
TH_3203|M.thermoresistible__bu PVQILQ
MMAR_2611|M.marinum_M PVRKA-
MUL_3150|M.ulcerans_Agy99 PVRKA-
Mvan_3476|M.vanbaalenii_PYR-1 QPERV-
Mflv_3051|M.gilvum_PYR-GCK APEKV-
MSMEG_4187|M.smegmatis_MC2_155 KPEKI-
.