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MTEHVSPDNFIRAETDLYFGNVVRDGVLGRFKHFRDFGPLDNQLVVRQNRDTLYSVAVFDLEAGPVAVTL PDAGDRFRSLQVITEDHYVPEVIYTAGRHTFDRDGIGTRYVMLVLRVLVDPTDPADLATVHALQDGITVD QRSAGSFEVPDWDPVSQKAVRDALITLFGTLPDSRQMFGPVDEVDPVRRLIGAAAAWGGNPERDALYLTV NPDTNDGQTVHRLTVGDVPVDGFWSVTVYNAEGYFTPNPADAYSVNSVTGVRDPDGSVTIQFGGAADLIG DGVNHLPVTPGWNYLVRLYRPRPEVLDGSWSFPAAEPV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2722 | - | - | 100% (318) | hypothetical protein Mvan_2722 |
| M. vanbaalenii PYR-1 | Mvan_3476 | - | 4e-13 | 33.33% (159) | hypothetical protein Mvan_3476 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3687 | - | 7e-76 | 78.11% (169) | hypothetical protein Mflv_3687 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0084 | - | 1e-114 | 61.66% (313) | hypothetical protein MAB_0084 |
| M. marinum M | MMAR_2611 | - | 8e-11 | 32.35% (136) | hypothetical protein MMAR_2611 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_4187 | - | 4e-13 | 27.86% (201) | hypothetical protein MSMEG_4187 |
| M. thermoresistible (build 8) | TH_3203 | - | 2e-15 | 34.75% (141) | PUTATIVE putative conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3150 | - | 3e-11 | 32.35% (136) | hypothetical protein MUL_3150 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2611|M.marinum_M --------------------------------------------MSTLSS
MUL_3150|M.ulcerans_Agy99 --------------------------------------------MSTLSS
TH_3203|M.thermoresistible__bu --------------------------------------------------
Mvan_2722|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3687|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0084|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_4187|M.smegmatis_MC2_155 MRQTGSLRPILVPVWILVLVAALAGCATRTDDQPTESAPPPAQQAPPTPA
MMAR_2611|M.marinum_M GLRTLSYEAFIYFYPLVMMDVTRLQALNAAPGTGPGAGPPNHFSHMRAFP
MUL_3150|M.ulcerans_Agy99 GLRTLSYEAFIYFYPLVMMDVTRLQALNAAPSTGPGAGPPNHFSHMRAFP
TH_3203|M.thermoresistible__bu ---------------------------------------MNQLAHLGFLP
Mvan_2722|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_3687|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0084|M.abscessus_ATCC_1997 -----------------MRWLAASALIGVSAVLVGCSPSPRPPADGEAAS
MSMEG_4187|M.smegmatis_MC2_155 EIRAIAKDAYIWGFPLVDNYRVQYSYFVDKTDP-EYKGGFNEVHNTARLY
MMAR_2611|M.marinum_M SADFRAVVRPNFDTLYSSAWLDLRNGPVRLQSADTD-DRYYMLPMLDMWT
MUL_3150|M.ulcerans_Agy99 SADFRAVVRPNFDTLYSSAWLDLRNGPVRLQSADTD-DRYYMLPMLDMWT
TH_3203|M.thermoresistible__bu TAEFTGVVRPNVDTLYTSMFFDVSAEPLIVTVPPMG-DRYHLFPLLDMWT
Mvan_2722|M.vanbaalenii_PYR-1 -----------MTEHVSPDNFIRAETDLYFGNVVRD-GVLGRFKHFRDFG
Mflv_3687|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0084|M.abscessus_ATCC_1997 SAPFPDRRTPDGAIIVTPDNFARAETDLYFGNIVKD-GGFGTFHHIRELS
MSMEG_4187|M.smegmatis_MC2_155 TPADKAIQTPNADTPYSFVGADLRTEPLVFTVPPIEQNRYFSLQFVDGYT
MMAR_2611|M.marinum_M DVFANPGKRTS---GTGPLDLVIAGPGYQGESGE---QPRPTTVVAAPTP
MUL_3150|M.ulcerans_Agy99 DVFANPGKRTS---GTGPLDLVIAGPGYQGESGESGEQPRPTTVVAAPTP
TH_3203|M.thermoresistible__bu NVDASPGTRTVDDAGTG-YEFAIVGPNWHG------DLPEGVREYRSATD
Mvan_2722|M.vanbaalenii_PYR-1 PLDNQLVVRQN-------RDTLYSVAVFD--------LEAGPVAVTLPDA
Mflv_3687|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0084|M.abscessus_ATCC_1997 PLDRQLVIRQN-------RDTLYSSAVFD--------LDAGPVSISTPDP
MSMEG_4187|M.smegmatis_MC2_155 YNVAYVGSRTT---GNGGGRYLLAGPGWEGE-----KPEGVDEIIRSDTD
MMAR_2611|M.marinum_M FVWIIGRTQTNGPADYPAVHRVQDGYSLTELGSG----AQASAGDKRPDF
MUL_3150|M.ulcerans_Agy99 FVWIIGRTQTNGPADYPAVHRVQDGYFLTELGSG----AQASAGDKRPDF
TH_3203|M.thermoresistible__bu AGWMIGRIQVNGPEDMPAVIDLQNAMTAVPLSAHGTPYEPPGNADLRPDW
Mvan_2722|M.vanbaalenii_PYR-1 GDRFRSLQVITEDHYVPEVIYTAGRHTFDRDGIG----------------
Mflv_3687|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0084|M.abscessus_ATCC_1997 GQRFMSLQLITEDHYVPAVFYGKGQHTITKEQTG----------------
MSMEG_4187|M.smegmatis_MC2_155 LAFVLYRTQLFGPRDLDNIKKIQAGYQVAPLSVYLKQPSPPPAPPIDFTP
MMAR_2611|M.marinum_M DLTTEPPRIVNGMAALDYLSYAADLLCVNPPHPTDYSVLARLANLGIEAG
MUL_3150|M.ulcerans_Agy99 DLTTEPPRIVNGMAALDYLSYAADLLCVNSPHPTDYSVLARLANLGIEAG
TH_3203|M.thermoresistible__bu PRGREVSRYIHDLSPQQYWDLFYSGLSHDQPRPGDEVLLERLAAVGWSPT
Mvan_2722|M.vanbaalenii_PYR-1 ------TRYVMLVLR----------VLVDPTDPADLATVHALQDG-----
Mflv_3687|M.gilvum_PYR-GCK --------------------------------------------------
MAB_0084|M.abscessus_ATCC_1997 ------TRYIAAVVR----------TLVDPGDPADLVQVHALQDG-----
MSMEG_4187|M.smegmatis_MC2_155 PLTPEAQKTSPQFFEILN-----AALRYAPVKPEEQEMRERFARIGIGPD
MMAR_2611|M.marinum_M SPFDASRFDADQVAELERGRSDALNDILKSATKLGANVDG-WISLTESMG
MUL_3150|M.ulcerans_Agy99 SPFDASRFDADQVAELERGRSDALNDILKSATKLGANVDG-WISLTESMG
TH_3203|M.thermoresistible__bu EKLDLAQLPDDERDVWEQAWPQALSQIEVDLG--SEEVNG-WLLARTGLG
Mvan_2722|M.vanbaalenii_PYR-1 ITVDQRSAGSFEVPDWDPVSQKAVRDALITLFGTLPDSRQ-MFGPVD---
Mflv_3687|M.gilvum_PYR-GCK ------------MPEWDPGSQKQVRDALAALFATLPDTRG-MFGAAG---
MAB_0084|M.abscessus_ATCC_1997 VSARQEKPGAFDVPKWDGASQRKVRDGLLQLAATLPDTTA-MFGAKA---
MSMEG_4187|M.smegmatis_MC2_155 GDFDADKLSPETREAIEDGMANAWVEFDRFKQDKVDTGEVGSAQLFGTAD
: :
MMAR_2611|M.marinum_M VYGNNYLRRAVVALIGLGANPAEDAVYPFLATDEHGDPLAGEHDYVIHFD
MUL_3150|M.ulcerans_Agy99 VYGNNYLRRAVVALIGLGANPAEDAVYPFLATDEHGDPLAGEHDYVIHFD
TH_3203|M.thermoresistible__bu DYGTDYATRAVVAHGGLGANLPSDAVYPTVRVDDTGAQLNAANDYVLRFS
Mvan_2722|M.vanbaalenii_PYR-1 --EVDPVRRLIGAAAAWGGNPERDALYLTVNPDTN------DGQTVHRLT
Mflv_3687|M.gilvum_PYR-GCK --EVDPVRRLIGAAAAWGGNPERDALYLTVDPAAD------DGRTPHRLT
MAB_0084|M.abscessus_ATCC_1997 --TTDPVRHLIGTASAWGGNPEKDALYLTVNPAKN------DGTTVYRLT
MSMEG_4187|M.smegmatis_MC2_155 DLKGNYLYRMAGAVLGIYGNTAAEALYPSAMLDADGQPLTGTNSYTYRFA
: : : . .* :*:* ::
MMAR_2611|M.marinum_M ADKLPPVDAFWSVTMYDA-EGFQVANELNRFAIGDR--DELRYNDDGSLD
MUL_3150|M.ulcerans_Agy99 ADKLPPVDAFWSVTMYDA-EGFQVANELNRFAIGDR--DELRYNDDGSLD
TH_3203|M.thermoresistible__bu PEDLPPVRGFWSLTLYDD-RGFFVDNPLDRYALRG---ERLTTNPDGSVD
Mvan_2722|M.vanbaalenii_PYR-1 VGDVP-VDGFWSVTVYNA-EGYFTPNPADAYSVNS---VTGVRDPDGSVT
Mflv_3687|M.gilvum_PYR-GCK VGDVP-VDGFWSVTVYNA-EGYFTPNPAGAYSVNS---VTAVKDADGSVM
MAB_0084|M.abscessus_ATCC_1997 VGPVP-VDGFWSVTVYNK-DGYFTPNARNAYSLNN---ITARHGTGGQTT
MSMEG_4187|M.smegmatis_MC2_155 PDQLPPVNAFWSLTIYELPSSQLVDNPIDRYLINSEMLPSLVPDPDGAYT
:* * .***:*:*: . . * . : : . . .*
MMAR_2611|M.marinum_M LCLAHTDPGPERQSNWLPAP-LGPLGVTMRLYAPRPEVVAGEWSPPPVRK
MUL_3150|M.ulcerans_Agy99 LYLAHTDPGPERQSNWLPAP-LGPLGVTMRLYAPRPEVVAGEWSPPPVRK
TH_3203|M.thermoresistible__bu VYVRHEPPGSDREANWLPTPETGDFNLMLRLYWPEAEILDGGWNPPPVQI
Mvan_2722|M.vanbaalenii_PYR-1 IQFGGAADLIGDGVNHLPVT--PGWNYLVRLYRPRPEVLDGSWSFPAAEP
Mflv_3687|M.gilvum_PYR-GCK VRFGGPAGEP----NHLPIT--PGWNYLVRLYRPRAEILDGSWTFPVAEP
MAB_0084|M.abscessus_ATCC_1997 VQFGGCAPTT---MNCLPIT--PGWNYMVRLYRAQRRFSTAAGSFPRRCP
MSMEG_4187|M.smegmatis_MC2_155 LRIQNTQPPEN-EANWLPAP-KGPFTLVLRLYWPKPDALNGTWQAPKPEK
: . * ** . :*** .. . *
MMAR_2611|M.marinum_M A---------------------------------------------
MUL_3150|M.ulcerans_Agy99 A---------------------------------------------
TH_3203|M.thermoresistible__bu LQ--------------------------------------------
Mvan_2722|M.vanbaalenii_PYR-1 V---------------------------------------------
Mflv_3687|M.gilvum_PYR-GCK G---------------------------------------------
MAB_0084|M.abscessus_ATCC_1997 SRRPNLMGCNDLGDLLGNFGAHIRVGHVIQAESRTQAGPHQPPAKL
MSMEG_4187|M.smegmatis_MC2_155 I---------------------------------------------