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MVTGKDEDLQLGEVVSTVEMAEALRASGAVDDLLAQIDSGEVALTGEGGLLPGLIKLALERGLAAELTDH LGYEKGDPAGRALPNARNGSSAKTVQTEAGPVPLDVPRDRDGSFTPRLVPKGQRRIGGLDDMIISLYAGG MTLRDIQFHLASTIGTDVSHETISKIVDEISEEVLVWQRRPLDPIYPVIYLDAIVVKVKDGGHTRNKAAH IAVGVDMAGIKHVLGIWVQQNEGAAFWASVCADLSNRGIRDVLIVCCDGLTGFPEAIAATWSQAAVQTCV VHLIRNALRFVSYSDRKTVAAALKPIYTAPNAEAARAELDAFTASELGKKNPTVTRVFERAWEQFIPFLA FPPELRRVIYTTNSIESLNYQLRKVTKTRGQFPNDAAAVKLLWLAICNIEDKRAAERAKERKQKRCRTAP GRLVEGQVVTNWKKALEQLVLVYPDRIEPYL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3425 | - | - | 100% (451) | transposase, mutator type |
| M. vanbaalenii PYR-1 | Mvan_2656 | - | 0.0 | 100.00% (451) | transposase, mutator type |
| M. vanbaalenii PYR-1 | Mvan_5974 | - | e-130 | 52.55% (432) | transposase, mutator type |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0944c | - | 7e-94 | 41.28% (436) | putative transposase |
| M. gilvum PYR-GCK | Mflv_3191 | - | 9e-38 | 30.13% (375) | transposase, mutator type |
| M. tuberculosis H37Rv | Rv0920c | - | 3e-94 | 41.51% (436) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3254 | - | 1e-130 | 52.74% (419) | transposase, Mutator family protein |
| M. smegmatis MC2 155 | MSMEG_4154 | - | 2e-35 | 31.36% (338) | transposase, Mutator family protein |
| M. thermoresistible (build 8) | TH_3008 | - | 1e-166 | 66.36% (434) | PUTATIVE transposase, mutator type |
| M. ulcerans Agy99 | MUL_0966 | - | 6e-91 | 39.62% (419) | transposase for IS2606 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0944c|M.bovis_AF2122/97 -MDAAQVIEPAHAGQDVDEAAVAARELSG----AERALVGDLVRQARAEG
Rv0920c|M.tuberculosis_H37Rv -MDAAQVIEPAHAGQDVDEAAVAARELSG----AERALVGDLVRQARAEG
MUL_0966|M.ulcerans_Agy99 MMTKTVVAVQPSQNHEDGAGAVAAIDVPSSRDVDELEVARELVRQAREAG
Mvan_3425|M.vanbaalenii_PYR-1 MVTGKDEDL-QLGEVVSTVEMAEALRASG--------AVDDLLAQIDSGE
TH_3008|M.thermoresistible__bu -MTMTDE---KGTSSTTGNELVAQLQASG--------ALDELFAKIDSGE
MAV_3254|M.avium_104 -MSRSDS------SRDEAAKQLAQVLPPA--------ALDALLADAEASG
Mflv_3191|M.gilvum_PYR-GCK -MTQDHS---------------------------------ALLAQLDALR
MSMEG_4154|M.smegmatis_MC2_155 -MTQDHS---------------------------------ALLAQLDALK
: *. .
Mb0944c|M.bovis_AF2122/97 VALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSR
Rv0920c|M.tuberculosis_H37Rv VALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSR
MUL_0966|M.ulcerans_Agy99 VGLTGPGGLLKAMTKTVIETALNEELSEHLGYDRHDRAGYGSGNSRNGTR
Mvan_3425|M.vanbaalenii_PYR-1 VALTGEGGLLPGLIKLALERGLAAELTDHLGYEKGDPAGRALPNARNGSS
TH_3008|M.thermoresistible__bu VEITGSDGLLPALLKTTLERGLQAELTGHLGYEKGEPAPAKRPNARNGTT
MAV_3254|M.avium_104 TPIDGPDGLLAQITKSVLERALDVEIADHLGYEHGDPAGNGSGNSRNGHG
Mflv_3191|M.gilvum_PYR-GCK SADAG--AVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGHR
MSMEG_4154|M.smegmatis_MC2_155 SADAG--AVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
* .:: : : :: : * : :* : : ***
Mb0944c|M.bovis_AF2122/97 NKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKG
Rv0920c|M.tuberculosis_H37Rv NKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKG
MUL_0966|M.ulcerans_Agy99 SKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYARG
Mvan_3425|M.vanbaalenii_PYR-1 AKTVQTEAG-PVPLDVPRDRDGSFTPRLVPKGQRRIGGLDDMIISLYAGG
TH_3008|M.thermoresistible__bu SKTIESEVG-SFTIDVPRDRAGTFTPRLIRKGQRRLDGLDDMIISLYAGG
MAV_3254|M.avium_104 RKTVLTTAG-PVDLEVPRDRNGTFDPVIVPKRKRRLGQVEDMILSLYARG
Mflv_3191|M.gilvum_PYR-GCK PKTVSTTSG-DIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG
MSMEG_4154|M.smegmatis_MC2_155 PKTVSTTAG-DVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG
*.: : . : :*: * *:* * :: : :* :. :::. *. *
Mb0944c|M.bovis_AF2122/97 LTTGEIAAHFADV-YGVSVSKDTISRITDRVIEEMQAWWSRPLEK-VYAA
Rv0920c|M.tuberculosis_H37Rv LTTGEIAAHFADV-YGVSVSKDTISRITDRVIEEMQAWWSRPLEK-VYAA
MUL_0966|M.ulcerans_Agy99 LTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEMTAWHTRPLER-VYAA
Mvan_3425|M.vanbaalenii_PYR-1 MTLRDIQFHLAST-IGTDVSHETISKIVDEISEEVLVWQRRPLDP-IYPV
TH_3008|M.thermoresistible__bu MTVREIEHHLATT-IGVELSAGTISAITDAVADAVLQWQNRPLEE-FYPV
MAV_3254|M.avium_104 MSTRDITEHLAEV-YGASVSAATVSRVTEVVADEIAAWQSRPVDP-VYPI
Mflv_3191|M.gilvum_PYR-GCK VSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFPY
MSMEG_4154|M.smegmatis_MC2_155 VSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFPY
:: .: .* :* :* : : : : *.: :.
Mb0944c|M.bovis_AF2122/97 VFIDAIMVKIRDG-QVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKF
Rv0920c|M.tuberculosis_H37Rv VFIDAIMVKIRDG-QVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKF
MUL_0966|M.ulcerans_Agy99 VFIDALHVKIRDG-QVGPRPVYAAVGVDLAGHRDVLGMWAGEDDGESAKY
Mvan_3425|M.vanbaalenii_PYR-1 IYLDAIVVKVKDGGHTRNKAAHIAVGVDMAGIKHVLGIWVQQNEG--AAF
TH_3008|M.thermoresistible__bu IYLDAIRIKVRQDHRVVGRSAYIAVGVDLEGIKHVLGIWVQDTEG--ASF
MAV_3254|M.avium_104 LYIDAIRLKIRDGGVVSNKAAHVVIGVDVEGIKQVLGVWIQQTEG--AKF
Mflv_3191|M.gilvum_PYR-GCK IFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVGDSES--FEF
MSMEG_4154|M.smegmatis_MC2_155 VFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVGDSES--FEF
:: ** *:: . . :. . **.: * :.:** : :. :
Mb0944c|M.bovis_AF2122/97 WLAVLTELRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRN
Rv0920c|M.tuberculosis_H37Rv WLAVLTDLRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRN
MUL_0966|M.ulcerans_Agy99 WLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIRG
Mvan_3425|M.vanbaalenii_PYR-1 WASVCADLSNRGIRDVLIVCCDGLTGFPEAIAATWSQAAVQTCVVHLIRN
TH_3008|M.thermoresistible__bu WAHVCADLANRGVRDVLIVCCDGLAGLPEAIEATWPDSMVQTCVVHLIRA
MAV_3254|M.avium_104 WHGVLTELRNRGCRDALFVCCDGLAGLPESIAAVWPQAVIQTCVVHLLRA
Mflv_3191|M.gilvum_PYR-GCK WREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMRN
MSMEG_4154|M.smegmatis_MC2_155 WREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMRN
* . :.* ** . :: .*. *: :: :. : * * :*::*
Mb0944c|M.bovis_AF2122/97 TFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAE-KWGKPYPAITR
Rv0920c|M.tuberculosis_H37Rv TFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAE-KWGKPYPAITR
MUL_0966|M.ulcerans_Agy99 TFRYPGRQHHTAIARALKPIYTAVNAAAAAEALDAFDT-EWGHRYPAAIR
Mvan_3425|M.vanbaalenii_PYR-1 ALRFVSYSDRKTVAAALKPIYTAPNAEAARAELDAFTASELGKKNPTVTR
TH_3008|M.thermoresistible__bu SMRFVSYGDRKKVAAELKKIYTAPNEETALAALAEFEASAWGAKYPQTVA
MAV_3254|M.avium_104 SMRYASYTDRKKMAAALRPIYTAATEQAAAVALEQFRT-EWKAKSPGAVA
Mflv_3191|M.gilvum_PYR-GCK LHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVAD-TLAPSFPKVAA
MSMEG_4154|M.smegmatis_MC2_155 LHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVAD-TLAASFPKVAA
. :: :: *:: . . *
Mb0944c|M.bovis_AF2122/97 LWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQ
Rv0920c|M.tuberculosis_H37Rv LWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQ
MUL_0966|M.ulcerans_Agy99 LWRNAWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTEQ
Mvan_3425|M.vanbaalenii_PYR-1 VFERAWEQFIPFLAFPPELRRVIYTTNSIESLNYQLRKVTKTRGQFPNDA
TH_3008|M.thermoresistible__bu TWTAAWERFTPFLQFPPMLRRVIYTTNSIESLNFQLRKVTKNRGHFPSTE
MAV_3254|M.avium_104 VWDRSWAEFVPFLAFPVEIRKIIYTTNAIESLNYQLRKVTKARGSFPSDA
Mflv_3191|M.gilvum_PYR-GCK MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
MSMEG_4154|M.smegmatis_MC2_155 MMDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY---
: . .* : : :.*.* *
Mb0944c|M.bovis_AF2122/97 SALKTLYLVTRSLDPKGTGQT--------------------KWAVRWKPA
Rv0920c|M.tuberculosis_H37Rv SALKTLYLVTRSLDPKGTGQT--------------------KWAVRWKPA
MUL_0966|M.ulcerans_Agy99 SALKCLYLVTRSLDPTGTGQK--------------------RWTTRWKPA
Mvan_3425|M.vanbaalenii_PYR-1 AAVKLLWLAICNIEDKRAAERAKER-KQKRCRTAPGRLVEGQVVTNWKKA
TH_3008|M.thermoresistible__bu SAVKLLWLAICNIEDRRARERAAEKGKPAGQRRASGRLVEGQVTTNWKQA
MAV_3254|M.avium_104 AAMKLLYLAIRNINQKRGSA-------------------QGQGTYRWTEA
Mflv_3191|M.gilvum_PYR-GCK AFLRLATAVVIEAHDEWQVTRR---------------YLSDISMDELRVV
MSMEG_4154|M.smegmatis_MC2_155 ---------VDHEGSEWSVLR----------------SGCGYLQPSMKQI
Mb0944c|M.bovis_AF2122/97 LNALAITFADRMPAAEER
Rv0920c|M.tuberculosis_H37Rv LNALAITFADRMPAAEER
MUL_0966|M.ulcerans_Agy99 LNAFAITFADRMPGSETT
Mvan_3425|M.vanbaalenii_PYR-1 LEQLVLVYPDRIEPYL--
TH_3008|M.thermoresistible__bu LAQLAAAYPDRINPYL--
MAV_3254|M.avium_104 LNAFAIQFPDRLPL----
Mflv_3191|M.gilvum_PYR-GCK IEKKHAAAALAKQHQIT-
MSMEG_4154|M.smegmatis_MC2_155 LEGRCACCEGGFTALVA-
: