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WLREPVDHPLDPLRADEFAAAAAILRRDHGVQAEPGGGSGWRFASIELIEPSKAELAAFDDGGPWPDRRA AVVCFDRGANATYKCVVSLTGDRVEEFEHIPGVQANFTVDEFTECDQLLRTHPDVIAALRGRGVTDIDLV FFDTWTYGDAVAPPEFRDRRIGWSDSWVKAAPGANPYARLLSGLHCVIDLNSMELLRVEDEGPFGTGAGA PDGTGAGASPPEVMGEYVPRHIPERILSAMRREPLKPLHVTQPEGPSFTLDGNLVQWQNWSLRVGFNHRE GMTLHTVRYRDGERQRSIAHRMSFAEMVVPYRDPSPDHYRRTAFDIGEWGLGFMTTSLELGCDCLGEIRY LDAVLHNSKGEPYAIRNAICIHEEDNAVLWKHVDHDIGAEVRRMRRLTLSFHVTVANYEYLVYWRLYQDG NIECEVRATGIMVTTPLPTGADNPNGTTVDERTYAPFHQHFLVARLDMDVDGSDNTVYMTESFAEPVGPD NPHGLSLVQRNTPLRTEGEARQDVNFATQRAWKVVNPNVVTGIGAHPAYKLVPTGAIPPMFDPGSPVLQR ASVIGHTLWVTPNRPDERWPAGEFVNQSAQDTGLARWTAADRGIENTDVVLWYVFGIHHITRPEDWPVMP VDIVSFWLKPFGFFDRNPALDVVGTPPDACHTSATSVHH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3407 | tynA | - | 100% (670) | tyramine oxidase |
| M. vanbaalenii PYR-1 | Mvan_2218 | tynA | e-139 | 41.27% (659) | tyramine oxidase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3126 | tynA | 0.0 | 85.54% (664) | tyramine oxidase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4204 | tynA | 0.0 | 70.27% (656) | tyramine oxidase |
| M. marinum M | MMAR_2608 | tynA | 0.0 | 65.60% (654) | copper methylamine oxidase precursor, MaoX |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3847 | tynA | 0.0 | 79.17% (672) | tyramine oxidase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3407|M.vanbaalenii_PYR-1 -MWLREPVDHP------LDPLRADEFAAAAAILRRDHGVQAEP---GGGS
Mflv_3126|M.gilvum_PYR-GCK ---MSEHHDSPPAGPFPLDPLGAAEFAAVAAILRRDRDVEIAPAPTGSAP
MSMEG_3847|M.smegmatis_MC2_155 -MWLRDRVDYP------LDPLSADEFTAVAAILRREH---------GVGE
MAB_4204|M.abscessus_ATCC_1997 ----MNDTFHP------LDPLSAEEFTTVAKILAQTH---------DVGA
MMAR_2608|M.marinum_M MTETIVQTFHP------LDPLTESEFQQAVSVVRRDR---------NITE
* **** ** .. :: : : .
Mvan_3407|M.vanbaalenii_PYR-1 GWRFASIELIEPSKAELAAFDDGGPWPDRRAAVVCFDRGANATYKCVVSL
Mflv_3126|M.gilvum_PYR-GCK GWRFASIEMIEPAKAALADFERGGPRPARRAEAVCFDRAANATYKCVVSL
MSMEG_3847|M.smegmatis_MC2_155 GWRIASVELAEPSKAELAAYDEGGPAPARRAAVICLDRSANATYKGFVSL
MAB_4204|M.abscessus_ATCC_1997 SWRYTSVELSEPSKAEVAAFDNNGTRPDRRALATCLDTTQNATYKAVISL
MMAR_2608|M.marinum_M RWRFASMELAEPGKREIADFENNAVVPDRRAVIVCFDRDTNGTYKALVSL
** :*:*: **.* :* :: .. * *** *:* *.*** .:**
Mvan_3407|M.vanbaalenii_PYR-1 TGDRVEEFEHIPGVQANFTVDEFTECDQLLRTHPDVIAALRGRGVTDIDL
Mflv_3126|M.gilvum_PYR-GCK TDDRVESFEHVPGVQPNFTVDEFVECDQLLRGHPEVIAALLGRGITDIGL
MSMEG_3847|M.smegmatis_MC2_155 TDDRVESFTHIPGVQANFTVDEFAECDQILRSHPDVIAALARRGITDMDN
MAB_4204|M.abscessus_ATCC_1997 TSGEVLSWNHIPGVQPNFTVDEWEEADAVLRGHPDVIAALARRGITDMDL
MMAR_2608|M.marinum_M SGDRILSWTCLPGVQPNITHDEWLEAGEVLRSHPAVIAALCRRGITDLEN
:...: .: :****.*:* **: *.. :** ** ***** **:**:
Mvan_3407|M.vanbaalenii_PYR-1 VFFDTWTYGDAVAPPEFRDRRIGWSDSWVKAAPGANPYARLLSGLHCVID
Mflv_3126|M.gilvum_PYR-GCK VFFDTWTYGDAVAPPEYRDRRIGWSDSWAKAAPGANPYARLVSGFHCVID
MSMEG_3847|M.smegmatis_MC2_155 VFMDTWTYGAAVAPPEYTDRRIGWSDTWYKSTAGANPYAHPVSGLHCVID
MAB_4204|M.abscessus_ATCC_1997 VFMDTWTYGDAVMPEKYRGRRLGWSDTWVRAADGANPYAGPVNGFHCVID
MMAR_2608|M.marinum_M MLVDVWAYGDALIPEAYRGRRLAWSDSWLTSPGGGNLYARHIKGFHCVID
::.*.*:** *: * : .**:.***:* :. *.* ** :.*:*****
Mvan_3407|M.vanbaalenii_PYR-1 LNSMELLRVEDEGPFGTGAGAPDGTGAGASPPEVMGEYVPRHIPERILSA
Mflv_3126|M.gilvum_PYR-GCK LNSMELLRIEDEGPFG-----PDGT--GETPPEVMGEYVPAHIPGHILAA
MSMEG_3847|M.smegmatis_MC2_155 LNAMEVLRVED-----------DGT---NERPDVMGEYVPRHIPERIRAA
MAB_4204|M.abscessus_ATCC_1997 MNSMELLDIED-----------TFT---VERPTMMGEYVPRHVPERLRKQ
MMAR_2608|M.marinum_M LNTMELLDIEE------------GS--PLEFPAVMAEYVPRHIPENLRDS
:*:**:* :*: : * :*.**** *:* .:
Mvan_3407|M.vanbaalenii_PYR-1 MRREPLKPLHVTQPEGPSFTLDGNLVQWQNWSLRVGFNHREGMTLHTVRY
Mflv_3126|M.gilvum_PYR-GCK GRRDPVKPLHITQPDGPSFSLDGNLLRWQNWSLRVGFNHREGMTLHTVRY
MSMEG_3847|M.smegmatis_MC2_155 STREPLKPLEITQPHGPSFTLDGNLLQWQNWSLRIGFNHREGMTLHTVRY
MAB_4204|M.abscessus_ATCC_1997 STRESLQPLHITQPDGPSFTIEGNKLQWQNWSLRVGFNYREGMTLHAVTY
MMAR_2608|M.marinum_M SVRGALRPLEIIQPDGPSFTLRGNHLEWQNWSLRVGFNYREGMTLHTVTY
* .::**.: **.****:: ** :.*******:***:*******:* *
Mvan_3407|M.vanbaalenii_PYR-1 RDGERQRSIAHRMSFAEMVVPYRDPSPDHYRRTAFDIGEWGLGFMTTSLE
Mflv_3126|M.gilvum_PYR-GCK RDGDRERSVAHRMSFAEMIVPYRDPSPDHYRRTAFDIGEWGLGFMTTSLE
MSMEG_3847|M.smegmatis_MC2_155 RDGAVNRSVAHRLSFAEMVVPYRDPSVDHYRRTAFDIGEWGLGFMTTSLD
MAB_4204|M.abscessus_ATCC_1997 NDNGRVRSVANRMSFAEMMVPYRDHCEDHYRRTAFDIGEWGIGFMTTSLE
MMAR_2608|M.marinum_M NDHGRVRPIAYRMSFAEMAVPYRDHCADHYRRTAFDIGEWGLGFMTTSLE
.* *.:* *:***** ***** . **************:*******:
Mvan_3407|M.vanbaalenii_PYR-1 LGCDCLGEIRYLDAVLHNSKGEPYAIRNAICIHEEDNAVLWKHVDHDIGA
Mflv_3126|M.gilvum_PYR-GCK LGCDCLGEIRYLDAVLHNSKGEPYTITNAICIHEEDNAVLWKHVDHDIGA
MSMEG_3847|M.smegmatis_MC2_155 LGCDCLGEIRYLDAVLHNSKGEPYTITNAICIHEEDNAVLWKHVDHDAGA
MAB_4204|M.abscessus_ATCC_1997 LGCDCLGEIRYLDAVLHNSKGEPYTIKNAICIHEEDNAVLWKHVDHDHGA
MMAR_2608|M.marinum_M KGCDCLGEIRYLDAVLHNSKGEPYTIKNAICIHEEDNAVLWKHVVCDGSA
***********************:* ***************** * .*
Mvan_3407|M.vanbaalenii_PYR-1 EVRRMRRLTLSFHVTVANYEYLVYWRLYQDGNIECEVRATGIMVTTPLPT
Mflv_3126|M.gilvum_PYR-GCK EVRRMRRLTISFHVTVANYEYLVYWRLYQDGNIECEVRATGIMVTTPLAV
MSMEG_3847|M.smegmatis_MC2_155 EVRRMRRLTLSFHVTVANYEYLVYWRLYQDGNIECEVRATGIMVTTPLPA
MAB_4204|M.abscessus_ATCC_1997 QVRRMRRLTVSFHVTVANYEYLTYWRFYQDGNIECEVRATGIMVVSNFTE
MMAR_2608|M.marinum_M EVRRMRRLTVSFHVTVANYEYLVYWRFYQDGNIECEIRATGLMVTTNFDN
:********:************.***:*********:****:**.: :
Mvan_3407|M.vanbaalenii_PYR-1 GAD-NPNGTTVDERTYAPFHQHFLVARLDMDVDGSDNTVYMTESFAEPVG
Mflv_3126|M.gilvum_PYR-GCK GAA-NPNGTLVDERTYAPFHQHFLVARLDMDIDGTDNTVVMSESFAEPIG
MSMEG_3847|M.smegmatis_MC2_155 GADAHPNGALVDERTYAPYHQHFLIARLDLDIDGPDNTVYMTESYAAPIG
MAB_4204|M.abscessus_ATCC_1997 GAA-HPHGTLVDNRTYAPYHQHFLVARLDLDVDGTENTVYATETEIEPVG
MMAR_2608|M.marinum_M GQA-HASGTLVDERTYAPYHQHFLTARLDLDIDGTDNTVYTSETEMVPTG
* :. *: **:*****:***** ****:*:**.:*** :*: * *
Mvan_3407|M.vanbaalenii_PYR-1 PDNPHGLSLVQRNTPLRTEGEARQDVNFATQRAWKVVNPNVVTGIGAHPA
Mflv_3126|M.gilvum_PYR-GCK PDNPHGLSLVVSNTPLRTEWEARQDVNFATQRAWKVVNPNVTTGLGAHPA
MSMEG_3847|M.smegmatis_MC2_155 PDNPYGLSVVVRNEALRTEADGIQDVNFATQRAWKVVNTNVVNGLGTHPS
MAB_4204|M.abscessus_ATCC_1997 PENPYGLSLRQRNTPLRTESEGKQDFCWETQRAWKVVNDNTRNGIGTAPA
MMAR_2608|M.marinum_M PDNPYGLSLRQRNIPLRTEEEGKQDYCWETQRAWRVVNENVTNGLGTHPS
*:**:***: * .**** :. ** : *****:*** *. .*:*: *:
Mvan_3407|M.vanbaalenii_PYR-1 YKLVPTGAIPPMFDPGSPVLQRASVIGHTLWVTPNRPDERWPAGEFVNQS
Mflv_3126|M.gilvum_PYR-GCK YKLVPTGAIPSMFEPGSPVLDRAGVIAHTLWVTPNRADERWPAGEFVNQS
MSMEG_3847|M.smegmatis_MC2_155 YKLVPTGAIPPMLDPESPVLQRANVIGHTLWVTPNHPDERWPAGEFVNQS
MAB_4204|M.abscessus_ATCC_1997 YKLVPGAAIPSMFDPSSPVLARCRAIEHTLWVTPNSPDERWPAGEFVTQS
MMAR_2608|M.marinum_M YKLVGGAAIPPMFDLRSPVLRRAEAITHTVWVTPNHPDERWPAGEFVNQS
**** .***.*:: **** *. .* **:***** .**********.**
Mvan_3407|M.vanbaalenii_PYR-1 AQDTGLARWTAADRGIENTDVVLWYVFGIHHITRPEDWPVMPVDIVSFWL
Mflv_3126|M.gilvum_PYR-GCK ARDTGLARWTAADRPIENTDVVLWYVFGIHHITRAEDWPVMPVDVVSFWL
MSMEG_3847|M.smegmatis_MC2_155 VRDTGLGEWTKANRSIDNADVVLWYVFGIHHITRPEDWPVMPVDIVSFWL
MAB_4204|M.abscessus_ATCC_1997 KEDHGLPAWTEGNRSIENTDVVLWYVFGIHHITRPEDWPIMPVDTVNFWL
MMAR_2608|M.marinum_M GPGLGLPAWTAANRSIENTDVVVWYTFGIHHITRPEDWPVMPADTVSFWL
. ** ** .:* *:*:***:**.********.****:**.* *.***
Mvan_3407|M.vanbaalenii_PYR-1 KPFGFFDRNPALDVVGTPPDACHTSATSVHH-
Mflv_3126|M.gilvum_PYR-GCK KPFGFFDRNPALDVVGTPPDSCHTATTSAHH-
MSMEG_3847|M.smegmatis_MC2_155 KPYGFFDRNPALDVPATPPGACAHPHTKAAHH
MAB_4204|M.abscessus_ATCC_1997 KPVGFFDRNPSLDVAPTPPKSCHMSGHQED--
MMAR_2608|M.marinum_M KPVGFFDRNPSLDVAPTAAATCHGEGGC----
** *******:*** *.. :*