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M. abscessus ATCC 19977 MAB_4204 (tynA)

annotation: tyramine oxidase
coordinates: 4270268 - 4272208
length: 646

MNDTFHPLDPLSAEEFTTVAKILAQTHDVGASWRYTSVELSEPSKAEVAAFDNNGTRPDRRALATCLDTT
QNATYKAVISLTSGEVLSWNHIPGVQPNFTVDEWEEADAVLRGHPDVIAALARRGITDMDLVFMDTWTYG
DAVMPEKYRGRRLGWSDTWVRAADGANPYAGPVNGFHCVIDMNSMELLDIEDTFTVERPTMMGEYVPRHV
PERLRKQSTRESLQPLHITQPDGPSFTIEGNKLQWQNWSLRVGFNYREGMTLHAVTYNDNGRVRSVANRM
SFAEMMVPYRDHCEDHYRRTAFDIGEWGIGFMTTSLELGCDCLGEIRYLDAVLHNSKGEPYTIKNAICIH
EEDNAVLWKHVDHDHGAQVRRMRRLTVSFHVTVANYEYLTYWRFYQDGNIECEVRATGIMVVSNFTEGAA
HPHGTLVDNRTYAPYHQHFLVARLDLDVDGTENTVYATETEIEPVGPENPYGLSLRQRNTPLRTESEGKQ
DFCWETQRAWKVVNDNTRNGIGTAPAYKLVPGAAIPSMFDPSSPVLARCRAIEHTLWVTPNSPDERWPAG
EFVTQSKEDHGLPAWTEGNRSIENTDVVLWYVFGIHHITRPEDWPIMPVDTVNFWLKPVGFFDRNPSLDV
APTPPKSCHMSGHQED
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_4204tynA-100% (646)tyramine oxidase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_3126tynA0.069.65% (649) tyramine oxidase
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. marinum MMMAR_2608tynA0.072.14% (639) copper methylamine oxidase precursor, MaoX
M. avium 104-----
M. smegmatis MC2 155MSMEG_3847tynA0.073.03% (634) tyramine oxidase
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_3407tynA0.070.27% (656) tyramine oxidase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_3126|M.gilvum_PYR-GCK          ---MSEHHDSPPAGPFPLDPLGAAEFAAVAAILRRDRDVEIAPAPTGSAP
Mvan_3407|M.vanbaalenii_PYR-1       -MWLREPVDHP------LDPLRADEFAAAAAILRRDHGVQAEP---GGGS
MSMEG_3847|M.smegmatis_MC2_155      -MWLRDRVDYP------LDPLSADEFTAVAAILRREH---------GVGE
MAB_4204|M.abscessus_ATCC_1997      ----MNDTFHP------LDPLSAEEFTTVAKILAQTH---------DVGA
MMAR_2608|M.marinum_M               MTETIVQTFHP------LDPLTESEFQQAVSVVRRDR---------NITE
                                              *      ****   **  .. :: : :         .   

Mflv_3126|M.gilvum_PYR-GCK          GWRFASIEMIEPAKAALADFERGGPRPARRAEAVCFDRAANATYKCVVSL
Mvan_3407|M.vanbaalenii_PYR-1       GWRFASIELIEPSKAELAAFDDGGPWPDRRAAVVCFDRGANATYKCVVSL
MSMEG_3847|M.smegmatis_MC2_155      GWRIASVELAEPSKAELAAYDEGGPAPARRAAVICLDRSANATYKGFVSL
MAB_4204|M.abscessus_ATCC_1997      SWRYTSVELSEPSKAEVAAFDNNGTRPDRRALATCLDTTQNATYKAVISL
MMAR_2608|M.marinum_M               RWRFASMELAEPGKREIADFENNAVVPDRRAVIVCFDRDTNGTYKALVSL
                                     ** :*:*: **.*  :* :: ..  * ***   *:*   *.*** .:**

Mflv_3126|M.gilvum_PYR-GCK          TDDRVESFEHVPGVQPNFTVDEFVECDQLLRGHPEVIAALLGRGITDIGL
Mvan_3407|M.vanbaalenii_PYR-1       TGDRVEEFEHIPGVQANFTVDEFTECDQLLRTHPDVIAALRGRGVTDIDL
MSMEG_3847|M.smegmatis_MC2_155      TDDRVESFTHIPGVQANFTVDEFAECDQILRSHPDVIAALARRGITDMDN
MAB_4204|M.abscessus_ATCC_1997      TSGEVLSWNHIPGVQPNFTVDEWEEADAVLRGHPDVIAALARRGITDMDL
MMAR_2608|M.marinum_M               SGDRILSWTCLPGVQPNITHDEWLEAGEVLRSHPAVIAALCRRGITDLEN
                                    :...: .:  :****.*:* **: *.. :** ** *****  **:**:  

Mflv_3126|M.gilvum_PYR-GCK          VFFDTWTYGDAVAPPEYRDRRIGWSDSWAKAAPGANPYARLVSGFHCVID
Mvan_3407|M.vanbaalenii_PYR-1       VFFDTWTYGDAVAPPEFRDRRIGWSDSWVKAAPGANPYARLLSGLHCVID
MSMEG_3847|M.smegmatis_MC2_155      VFMDTWTYGAAVAPPEYTDRRIGWSDTWYKSTAGANPYAHPVSGLHCVID
MAB_4204|M.abscessus_ATCC_1997      VFMDTWTYGDAVMPEKYRGRRLGWSDTWVRAADGANPYAGPVNGFHCVID
MMAR_2608|M.marinum_M               MLVDVWAYGDALIPEAYRGRRLAWSDSWLTSPGGGNLYARHIKGFHCVID
                                    ::.*.*:** *: *  : .**:.***:*  :. *.* **  :.*:*****

Mflv_3126|M.gilvum_PYR-GCK          LNSMELLRIEDEGPFG-----PDGT--GETPPEVMGEYVPAHIPGHILAA
Mvan_3407|M.vanbaalenii_PYR-1       LNSMELLRVEDEGPFGTGAGAPDGTGAGASPPEVMGEYVPRHIPERILSA
MSMEG_3847|M.smegmatis_MC2_155      LNAMEVLRVED-----------DGT---NERPDVMGEYVPRHIPERIRAA
MAB_4204|M.abscessus_ATCC_1997      MNSMELLDIED-----------TFT---VERPTMMGEYVPRHVPERLRKQ
MMAR_2608|M.marinum_M               LNTMELLDIEE------------GS--PLEFPAVMAEYVPRHIPENLRDS
                                    :*:**:* :*:             :      * :*.**** *:* .:   

Mflv_3126|M.gilvum_PYR-GCK          GRRDPVKPLHITQPDGPSFSLDGNLLRWQNWSLRVGFNHREGMTLHTVRY
Mvan_3407|M.vanbaalenii_PYR-1       MRREPLKPLHVTQPEGPSFTLDGNLVQWQNWSLRVGFNHREGMTLHTVRY
MSMEG_3847|M.smegmatis_MC2_155      STREPLKPLEITQPHGPSFTLDGNLLQWQNWSLRIGFNHREGMTLHTVRY
MAB_4204|M.abscessus_ATCC_1997      STRESLQPLHITQPDGPSFTIEGNKLQWQNWSLRVGFNYREGMTLHAVTY
MMAR_2608|M.marinum_M               SVRGALRPLEIIQPDGPSFTLRGNHLEWQNWSLRVGFNYREGMTLHTVTY
                                      * .::**.: **.****:: ** :.*******:***:*******:* *

Mflv_3126|M.gilvum_PYR-GCK          RDGDRERSVAHRMSFAEMIVPYRDPSPDHYRRTAFDIGEWGLGFMTTSLE
Mvan_3407|M.vanbaalenii_PYR-1       RDGERQRSIAHRMSFAEMVVPYRDPSPDHYRRTAFDIGEWGLGFMTTSLE
MSMEG_3847|M.smegmatis_MC2_155      RDGAVNRSVAHRLSFAEMVVPYRDPSVDHYRRTAFDIGEWGLGFMTTSLD
MAB_4204|M.abscessus_ATCC_1997      NDNGRVRSVANRMSFAEMMVPYRDHCEDHYRRTAFDIGEWGIGFMTTSLE
MMAR_2608|M.marinum_M               NDHGRVRPIAYRMSFAEMAVPYRDHCADHYRRTAFDIGEWGLGFMTTSLE
                                    .*    *.:* *:***** ***** . **************:*******:

Mflv_3126|M.gilvum_PYR-GCK          LGCDCLGEIRYLDAVLHNSKGEPYTITNAICIHEEDNAVLWKHVDHDIGA
Mvan_3407|M.vanbaalenii_PYR-1       LGCDCLGEIRYLDAVLHNSKGEPYAIRNAICIHEEDNAVLWKHVDHDIGA
MSMEG_3847|M.smegmatis_MC2_155      LGCDCLGEIRYLDAVLHNSKGEPYTITNAICIHEEDNAVLWKHVDHDAGA
MAB_4204|M.abscessus_ATCC_1997      LGCDCLGEIRYLDAVLHNSKGEPYTIKNAICIHEEDNAVLWKHVDHDHGA
MMAR_2608|M.marinum_M               KGCDCLGEIRYLDAVLHNSKGEPYTIKNAICIHEEDNAVLWKHVVCDGSA
                                     ***********************:* *****************  * .*

Mflv_3126|M.gilvum_PYR-GCK          EVRRMRRLTISFHVTVANYEYLVYWRLYQDGNIECEVRATGIMVTTPLAV
Mvan_3407|M.vanbaalenii_PYR-1       EVRRMRRLTLSFHVTVANYEYLVYWRLYQDGNIECEVRATGIMVTTPLPT
MSMEG_3847|M.smegmatis_MC2_155      EVRRMRRLTLSFHVTVANYEYLVYWRLYQDGNIECEVRATGIMVTTPLPA
MAB_4204|M.abscessus_ATCC_1997      QVRRMRRLTVSFHVTVANYEYLTYWRFYQDGNIECEVRATGIMVVSNFTE
MMAR_2608|M.marinum_M               EVRRMRRLTVSFHVTVANYEYLVYWRFYQDGNIECEIRATGLMVTTNFDN
                                    :********:************.***:*********:****:**.: :  

Mflv_3126|M.gilvum_PYR-GCK          GAA-NPNGTLVDERTYAPFHQHFLVARLDMDIDGTDNTVVMSESFAEPIG
Mvan_3407|M.vanbaalenii_PYR-1       GAD-NPNGTTVDERTYAPFHQHFLVARLDMDVDGSDNTVYMTESFAEPVG
MSMEG_3847|M.smegmatis_MC2_155      GADAHPNGALVDERTYAPYHQHFLIARLDLDIDGPDNTVYMTESYAAPIG
MAB_4204|M.abscessus_ATCC_1997      GAA-HPHGTLVDNRTYAPYHQHFLVARLDLDVDGTENTVYATETEIEPVG
MMAR_2608|M.marinum_M               GQA-HASGTLVDERTYAPYHQHFLTARLDLDIDGTDNTVYTSETEMVPTG
                                    *   :. *: **:*****:***** ****:*:**.:***  :*:   * *

Mflv_3126|M.gilvum_PYR-GCK          PDNPHGLSLVVSNTPLRTEWEARQDVNFATQRAWKVVNPNVTTGLGAHPA
Mvan_3407|M.vanbaalenii_PYR-1       PDNPHGLSLVQRNTPLRTEGEARQDVNFATQRAWKVVNPNVVTGIGAHPA
MSMEG_3847|M.smegmatis_MC2_155      PDNPYGLSVVVRNEALRTEADGIQDVNFATQRAWKVVNTNVVNGLGTHPS
MAB_4204|M.abscessus_ATCC_1997      PENPYGLSLRQRNTPLRTESEGKQDFCWETQRAWKVVNDNTRNGIGTAPA
MMAR_2608|M.marinum_M               PDNPYGLSLRQRNIPLRTEEEGKQDYCWETQRAWRVVNENVTNGLGTHPS
                                    *:**:***:   * .**** :. **  : *****:*** *. .*:*: *:

Mflv_3126|M.gilvum_PYR-GCK          YKLVPTGAIPSMFEPGSPVLDRAGVIAHTLWVTPNRADERWPAGEFVNQS
Mvan_3407|M.vanbaalenii_PYR-1       YKLVPTGAIPPMFDPGSPVLQRASVIGHTLWVTPNRPDERWPAGEFVNQS
MSMEG_3847|M.smegmatis_MC2_155      YKLVPTGAIPPMLDPESPVLQRANVIGHTLWVTPNHPDERWPAGEFVNQS
MAB_4204|M.abscessus_ATCC_1997      YKLVPGAAIPSMFDPSSPVLARCRAIEHTLWVTPNSPDERWPAGEFVTQS
MMAR_2608|M.marinum_M               YKLVGGAAIPPMFDLRSPVLRRAEAITHTVWVTPNHPDERWPAGEFVNQS
                                    ****  .***.*::  **** *. .* **:***** .**********.**

Mflv_3126|M.gilvum_PYR-GCK          ARDTGLARWTAADRPIENTDVVLWYVFGIHHITRAEDWPVMPVDVVSFWL
Mvan_3407|M.vanbaalenii_PYR-1       AQDTGLARWTAADRGIENTDVVLWYVFGIHHITRPEDWPVMPVDIVSFWL
MSMEG_3847|M.smegmatis_MC2_155      VRDTGLGEWTKANRSIDNADVVLWYVFGIHHITRPEDWPVMPVDIVSFWL
MAB_4204|M.abscessus_ATCC_1997      KEDHGLPAWTEGNRSIENTDVVLWYVFGIHHITRPEDWPIMPVDTVNFWL
MMAR_2608|M.marinum_M               GPGLGLPAWTAANRSIENTDVVVWYTFGIHHITRPEDWPVMPADTVSFWL
                                      . **  ** .:* *:*:***:**.********.****:**.* *.***

Mflv_3126|M.gilvum_PYR-GCK          KPFGFFDRNPALDVVGTPPDSCHTATTSAHH-
Mvan_3407|M.vanbaalenii_PYR-1       KPFGFFDRNPALDVVGTPPDACHTSATSVHH-
MSMEG_3847|M.smegmatis_MC2_155      KPYGFFDRNPALDVPATPPGACAHPHTKAAHH
MAB_4204|M.abscessus_ATCC_1997      KPVGFFDRNPSLDVAPTPPKSCHMSGHQED--
MMAR_2608|M.marinum_M               KPVGFFDRNPSLDVAPTAAATCHGEGGC----
                                    ** *******:***  *.. :*