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AEQPVDLSDEALAQAVSAASRAFDQASTLDELAKAKTEHLGDRSPIALARQALGSLPKTDRADAGKRVNV ARTQAQAGYDDRLAALRAERDAEVLVAERIDVTLPSTRQPVGARHPITILAENVADTFVAMGWELAEGPE VETEQFNFDALNFPPDHPARSEQDTFHIAPDGSRQVLRTHTSPVQVRTLLERELPVYVISIGRTFRTDEL DATHTPVFHQVEGLAVDKGLTMAHLRGTLDAFARAQFGPQGRTRFRPHFFPFTEPSAEVDIWFPNKKGGP GWVEWGGCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLPFGVGA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3317 | pheS | - | 100% (347) | phenylalanyl-tRNA synthetase subunit alpha |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1676 | pheS | 1e-165 | 82.65% (340) | phenylalanyl-tRNA synthetase subunit alpha |
| M. gilvum PYR-GCK | Mflv_3533 | pheS | 0.0 | 92.51% (347) | phenylalanyl-tRNA synthetase subunit alpha |
| M. tuberculosis H37Rv | Rv1649 | pheS | 1e-165 | 82.65% (340) | phenylalanyl-tRNA synthetase subunit alpha |
| M. leprae Br4923 | MLBr_01401 | pheS | 1e-166 | 80.86% (350) | phenylalanyl-tRNA synthetase subunit alpha |
| M. abscessus ATCC 19977 | MAB_2334 | pheS | 1e-162 | 80.83% (339) | phenylalanyl-tRNA synthetase alpha chain PheS |
| M. marinum M | MMAR_2456 | pheS | 1e-174 | 84.73% (347) | phenylalanyl-tRNA synthetase, alpha chain PheS |
| M. avium 104 | MAV_3120 | pheS | 1e-174 | 85.96% (342) | phenylalanyl-tRNA synthetase subunit alpha |
| M. smegmatis MC2 155 | MSMEG_3778 | pheS | 0.0 | 91.01% (345) | phenylalanyl-tRNA synthetase subunit alpha |
| M. thermoresistible (build 8) | TH_1591 | pheS | 0.0 | 86.99% (346) | Probable phenylalanyl-tRNA synthetase, alpha chain PheS |
| M. ulcerans Agy99 | MUL_1635 | pheS | 1e-174 | 84.44% (347) | phenylalanyl-tRNA synthetase subunit alpha |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1676|M.bovis_AF2122/97 -------------------MLSPEALTTAVDAAQQAIALADTLDVLARVK
Rv1649|M.tuberculosis_H37Rv -------------------MLSPEALTTAVDAAQQAIALADTLDVLARVK
MLBr_01401|M.leprae_Br4923 ---------MGDQPVDL-SMLSSEALAKAVNTARQAIALAVNLDALALIK
MMAR_2456|M.marinum_M ---------MGDQPVD----LSPQGLANVVKLAHQAFASADDLEALARAK
MUL_1635|M.ulcerans_Agy99 ---------MGDQPVD----LSPQGLANVVKLAHQAFASADNLEALARAK
Mvan_3317|M.vanbaalenii_PYR-1 ---------MAEQPVD----LSDEALAQAVSAASRAFDQASTLDELAKAK
Mflv_3533|M.gilvum_PYR-GCK ---------MAEQPVD----LSDQALADAVSAVRRAFDGASTLEDLAKAK
MSMEG_3778|M.smegmatis_MC2_155 MVRTQGGETAGEQPSD----LSEEALTKAVSAARHAFDAAGDLDALARAK
TH_1591|M.thermoresistible__bu -LAITYDRRVADRPLD----LSEEALTAVVSAAQRAFEQAADLDELSRAK
MAV_3120|M.avium_104 --------------MD----LSETALAEAVGAARQAFARAGDLDALARLK
MAB_2334|M.abscessus_ATCC_1997 ---------MADHTQHPSAESSAELLTTAVDAARAAFDTADNLDGLAQAK
* *: .* . *: * *: *: *
Mb1676|M.bovis_AF2122/97 TEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATL
Rv1649|M.tuberculosis_H37Rv TEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATL
MLBr_01401|M.leprae_Br4923 AEHLGDRSPLALARQALASLPKIDRAAVGKQVNTARSEVQRDYDERLATL
MMAR_2456|M.marinum_M TEHLGDRSPLALARQSLGTLPKEQRADAGKAVNLARGDAQCSYDERLAVL
MUL_1635|M.ulcerans_Agy99 TEHLGDRSPLALARQSLGTLPKEQRADAGKAVNLARGDAQCSYDERLAVL
Mvan_3317|M.vanbaalenii_PYR-1 TEHLGDRSPIALARQALGSLPKTDRADAGKRVNVARTQAQAGYDDRLAAL
Mflv_3533|M.gilvum_PYR-GCK TEYLGDRSPIALARQALGSLPKTERADAGKRVNVARTEAQTAYDERLAVL
MSMEG_3778|M.smegmatis_MC2_155 TEHLGDRAPIALARQALASLPKADRADAGKRVNVARAEAQRAYDERLAVL
TH_1591|M.thermoresistible__bu TEHLGDRSPIAQARQSLGTLPKSDRADAGKRVNFARAQVQRSYDERLAVL
MAV_3120|M.avium_104 TEHLGDRAPLALARQALGGVPKDQRADAGKRVNAARAQAQQAYDERLAEL
MAB_2334|M.abscessus_ATCC_1997 IDHLGEKSPLAQARQALGSLPKDQRAEAGKLVNAARTQAQQAYDDRLETL
::**:::*:* ***:*. :** :** .** ** ** .* **:** *
Mb1676|M.bovis_AF2122/97 RAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELA
Rv1649|M.tuberculosis_H37Rv RAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELA
MLBr_01401|M.leprae_Br4923 QAERDAAVLVTERIDVTLPSTRQPTGARHPITILAEHIADTFIAMGWELV
MMAR_2456|M.marinum_M RAERDAAVLVAERIDVTLPSTRQPTGARHPITILAEHIADTFIAMGWELA
MUL_1635|M.ulcerans_Agy99 RAERDAAVLVAERIDVTLPSTRQPTGARHPITILAEHIADTFIAMGWELA
Mvan_3317|M.vanbaalenii_PYR-1 RAERDAEVLVAERIDVTLPSTRQPVGARHPITILAENVADTFVAMGWELA
Mflv_3533|M.gilvum_PYR-GCK RAERDAAVLVAERIDVTLPSTRQPVGARHPITILAERVADTFVAMGWELA
MSMEG_3778|M.smegmatis_MC2_155 RAERDAAVLVAERIDVTLPSTRQPLGARHPITILAENIADTFVAMGWELA
TH_1591|M.thermoresistible__bu RAERDAAALVAERIDVTLPSTRQPLGARHPITILAERIADTFVAMGWELA
MAV_3120|M.avium_104 RAERDAAVLVAERIDVTLPSTRQPVGARHPITILAEHIADTFIAMGWELA
MAB_2334|M.abscessus_ATCC_1997 RAERDAAVLVAERIDVTLPSTRQPLGARHPITILSENIADTFIAMGWEVA
:***** .**:* ********* * ****** :*:*.:****:*****:.
Mb1676|M.bovis_AF2122/97 EGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQI
Rv1649|M.tuberculosis_H37Rv EGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQI
MLBr_01401|M.leprae_Br4923 DGPEVETEQFNFDALNFPADHPARSEQDTFYIAPDGSRQLLRTHTSPVQV
MMAR_2456|M.marinum_M EGPEVETEQFNFDALNFPPDHPARSEQDTFYIAPEDSRQLLRTHTSPVQV
MUL_1635|M.ulcerans_Agy99 EGPEVETEQFNFDALNFPPDHPARSEQDTFYIAPEDSRQLLRTHTSPVQV
Mvan_3317|M.vanbaalenii_PYR-1 EGPEVETEQFNFDALNFPPDHPARSEQDTFHIAPDGSRQVLRTHTSPVQV
Mflv_3533|M.gilvum_PYR-GCK EGPEVETEQFNFDALNFPPDHPARSEQDTFQVAPDGSRQVLRTHTSPVQI
MSMEG_3778|M.smegmatis_MC2_155 EGPEVETEQFNFDALNFPPDHPARSEQDTFQIAPDGSRQVLRTHTSPVQI
TH_1591|M.thermoresistible__bu EGPEVESEQFNFDALNFPQDHPARSEQDTFHVAPEGSRQVLRTHTSPVQI
MAV_3120|M.avium_104 EGPEVEAEQFNFDALNFPADHPARSEQDTFYIAPEGSRQLLRTHTSPVQV
MAB_2334|M.abscessus_ATCC_1997 DGPEVETEHFNFDALNFLPDHPARSTQDTFYIAPEDSRQVLRTHTSPVQV
:*****:*:******** *****. **** :**:.***:*********:
Mb1676|M.bovis_AF2122/97 RTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLR
Rv1649|M.tuberculosis_H37Rv RTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLR
MLBr_01401|M.leprae_Br4923 RTLLERELPVYVISIGRAFRTDEVDATHTPVFHQVEGLAVDRGLSMAHLR
MMAR_2456|M.marinum_M RTLLERELPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLR
MUL_1635|M.ulcerans_Agy99 RTLLERELPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLR
Mvan_3317|M.vanbaalenii_PYR-1 RTLLERELPVYVISIGRTFRTDELDATHTPVFHQVEGLAVDKGLTMAHLR
Mflv_3533|M.gilvum_PYR-GCK RALLERELPVYIVSIGRTFRTDELDATHTPVFHQVEGLAVDKGLTMANLR
MSMEG_3778|M.smegmatis_MC2_155 RALLERDLPVYIISIGRTFRTDELDSTHTPVFHQVEGLAVDKGLTMAHLR
TH_1591|M.thermoresistible__bu RALLERELPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDKGLTMAHLR
MAV_3120|M.avium_104 RTLLARELPVYVISIGRTFRTDELDATHTPVFHQVEGLAVDRGLSMAHLR
MAB_2334|M.abscessus_ATCC_1997 RTLLARELPVYVISLGRAFRTDEIDATHLPAFHQVEGLAVDRGLTLANLK
*:** *:****::*:**:*****:*:** * **********:**::*:*:
Mb1676|M.bovis_AF2122/97 GTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGADWVEWG
Rv1649|M.tuberculosis_H37Rv GTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGAAWVEWG
MLBr_01401|M.leprae_Br4923 GTLDIFARAEFGPSTRTRIRPHFFPFTEPSAEVDVWFASKKDGADWVEWG
MMAR_2456|M.marinum_M GTLDAFARSEFGPLARTRIRPHFFPFTEPSAEVDVWFANKKGGADWVEWG
MUL_1635|M.ulcerans_Agy99 GTLDAFARSEFGPLARTRIRPHFFPFTEPSAEVDVWFANKKGGADWVEWG
Mvan_3317|M.vanbaalenii_PYR-1 GTLDAFARAQFGPQGRTRFRPHFFPFTEPSAEVDIWFPNKKGGPGWVEWG
Mflv_3533|M.gilvum_PYR-GCK GTLDAFARSEFGPQGRTRFRPHFFPFTEPSAEVDIWFPDKKGGPGWVEWG
MSMEG_3778|M.smegmatis_MC2_155 GTLDAFARAQFGPEGRTRFRPHFFPFTEPSAEVDIWFPGKKGGPGWVEWG
TH_1591|M.thermoresistible__bu GTLDAFARSEFGPHGRTRFRPHFFPFTEPSAEVDVWFEGKKGGPGWVEWG
MAV_3120|M.avium_104 GTLDAFARAEFGPQARTRIRPHFFPFTEPSAEVDVWFVGKKGGAGWVEWG
MAB_2334|M.abscessus_ATCC_1997 GTLDAFARAMFGAQAHTRMRPHYFPFTEPSAEVDVWFENKKGGAGWVEWG
**** ***: **. :**:***:***********:** .* .*. *****
Mb1676|M.bovis_AF2122/97 GCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
Rv1649|M.tuberculosis_H37Rv GCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
MLBr_01401|M.leprae_Br4923 GCGMVHPNVLRATGIDPDIYSGFAFGMGLERTLQFRNSIPNMRDMVEGDV
MMAR_2456|M.marinum_M GCGMVHPNVLRAAGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
MUL_1635|M.ulcerans_Agy99 GCGMVHPNVLRAAGIDPEVYSGFAFGMGLERSLQFRNGIPDMRDMVEGDV
Mvan_3317|M.vanbaalenii_PYR-1 GCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
Mflv_3533|M.gilvum_PYR-GCK GCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
MSMEG_3778|M.smegmatis_MC2_155 GCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
TH_1591|M.thermoresistible__bu GCGMVDPNVLRACGIDPDVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDI
MAV_3120|M.avium_104 GCGMVHPNVLRAAGIDPDVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDM
MAB_2334|M.abscessus_ATCC_1997 GCGMVNPNVLRASGIDPGEYSGFAFGMGLERTLQFRNGLPDMRDMIEGDV
*****.****** **** ************:*****.:*:****:***:
Mb1676|M.bovis_AF2122/97 RFSLPFGVGA
Rv1649|M.tuberculosis_H37Rv RFSLPFGVGA
MLBr_01401|M.leprae_Br4923 RFSLPFGVGA
MMAR_2456|M.marinum_M RFSLPFGVGA
MUL_1635|M.ulcerans_Agy99 RFSLPFGVGA
Mvan_3317|M.vanbaalenii_PYR-1 RFSLPFGVGA
Mflv_3533|M.gilvum_PYR-GCK RFSLPFGVGA
MSMEG_3778|M.smegmatis_MC2_155 RFSLPFGVGA
TH_1591|M.thermoresistible__bu RFSLPFGVGL
MAV_3120|M.avium_104 RFSLPFGVGA
MAB_2334|M.abscessus_ATCC_1997 RFSLPFGVSA
********.