For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_3778 (pheS)

annotation: phenylalanyl-tRNA synthetase subunit alpha
coordinates: 3847685 - 3848755
length: 356

VRTQGGETAGEQPSDLSEEALTKAVSAARHAFDAAGDLDALARAKTEHLGDRAPIALARQALASLPKADR
ADAGKRVNVARAEAQRAYDERLAVLRAERDAAVLVAERIDVTLPSTRQPLGARHPITILAENIADTFVAM
GWELAEGPEVETEQFNFDALNFPPDHPARSEQDTFQIAPDGSRQVLRTHTSPVQIRALLERDLPVYIISI
GRTFRTDELDSTHTPVFHQVEGLAVDKGLTMAHLRGTLDAFARAQFGPEGRTRFRPHFFPFTEPSAEVDI
WFPGKKGGPGWVEWGGCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDVRFSLP
FGVGA*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_3778pheS-100% (356)phenylalanyl-tRNA synthetase subunit alpha

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1676pheS1e-16582.94% (340) phenylalanyl-tRNA synthetase subunit alpha
M. gilvum PYR-GCKMflv_3533pheS0.090.72% (345) phenylalanyl-tRNA synthetase subunit alpha
M. tuberculosis H37RvRv1649pheS1e-16582.94% (340) phenylalanyl-tRNA synthetase subunit alpha
M. leprae Br4923MLBr_01401pheS1e-16781.38% (349) phenylalanyl-tRNA synthetase subunit alpha
M. abscessus ATCC 19977MAB_2334pheS1e-16078.36% (342) phenylalanyl-tRNA synthetase alpha chain PheS
M. marinum MMMAR_2456pheS1e-17384.68% (346) phenylalanyl-tRNA synthetase, alpha chain PheS
M. avium 104MAV_3120pheS1e-17586.80% (341) phenylalanyl-tRNA synthetase subunit alpha
M. thermoresistible (build 8)TH_1591pheS0.088.66% (344) Probable phenylalanyl-tRNA synthetase, alpha chain PheS
M. ulcerans Agy99MUL_1635pheS1e-17284.10% (346) phenylalanyl-tRNA synthetase subunit alpha
M. vanbaalenii PYR-1Mvan_3317pheS0.091.01% (345) phenylalanyl-tRNA synthetase subunit alpha

CLUSTAL 2.0.9 multiple sequence alignment


Mb1676|M.bovis_AF2122/97            -------------------MLSPEALTTAVDAAQQAIALADTLDVLARVK
Rv1649|M.tuberculosis_H37Rv         -------------------MLSPEALTTAVDAAQQAIALADTLDVLARVK
MLBr_01401|M.leprae_Br4923          ---------MGDQPVDL-SMLSSEALAKAVNTARQAIALAVNLDALALIK
MMAR_2456|M.marinum_M               ---------MGDQPVD----LSPQGLANVVKLAHQAFASADDLEALARAK
MUL_1635|M.ulcerans_Agy99           ---------MGDQPVD----LSPQGLANVVKLAHQAFASADNLEALARAK
Mflv_3533|M.gilvum_PYR-GCK          ---------MAEQPVD----LSDQALADAVSAVRRAFDGASTLEDLAKAK
Mvan_3317|M.vanbaalenii_PYR-1       ---------MAEQPVD----LSDEALAQAVSAASRAFDQASTLDELAKAK
MSMEG_3778|M.smegmatis_MC2_155      MVRTQGGETAGEQPSD----LSEEALTKAVSAARHAFDAAGDLDALARAK
TH_1591|M.thermoresistible__bu      -LAITYDRRVADRPLD----LSEEALTAVVSAAQRAFEQAADLDELSRAK
MAV_3120|M.avium_104                --------------MD----LSETALAEAVGAARQAFARAGDLDALARLK
MAB_2334|M.abscessus_ATCC_1997      ---------MADHTQHPSAESSAELLTTAVDAARAAFDTADNLDGLAQAK
                                                         *   *: .*  .  *:  *  *: *:  *

Mb1676|M.bovis_AF2122/97            TEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATL
Rv1649|M.tuberculosis_H37Rv         TEHLGDRSPLALARQALAVLPKEQRAEAGKRVNAARNAAQRSYDERLATL
MLBr_01401|M.leprae_Br4923          AEHLGDRSPLALARQALASLPKIDRAAVGKQVNTARSEVQRDYDERLATL
MMAR_2456|M.marinum_M               TEHLGDRSPLALARQSLGTLPKEQRADAGKAVNLARGDAQCSYDERLAVL
MUL_1635|M.ulcerans_Agy99           TEHLGDRSPLALARQSLGTLPKEQRADAGKAVNLARGDAQCSYDERLAVL
Mflv_3533|M.gilvum_PYR-GCK          TEYLGDRSPIALARQALGSLPKTERADAGKRVNVARTEAQTAYDERLAVL
Mvan_3317|M.vanbaalenii_PYR-1       TEHLGDRSPIALARQALGSLPKTDRADAGKRVNVARTQAQAGYDDRLAAL
MSMEG_3778|M.smegmatis_MC2_155      TEHLGDRAPIALARQALASLPKADRADAGKRVNVARAEAQRAYDERLAVL
TH_1591|M.thermoresistible__bu      TEHLGDRSPIAQARQSLGTLPKSDRADAGKRVNFARAQVQRSYDERLAVL
MAV_3120|M.avium_104                TEHLGDRAPLALARQALGGVPKDQRADAGKRVNAARAQAQQAYDERLAEL
MAB_2334|M.abscessus_ATCC_1997      IDHLGEKSPLAQARQALGSLPKDQRAEAGKLVNAARTQAQQAYDDRLETL
                                     ::**:::*:* ***:*. :** :** .** ** **  .*  **:**  *

Mb1676|M.bovis_AF2122/97            RAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELA
Rv1649|M.tuberculosis_H37Rv         RAERDAAVLVAEGIDVTLPSTRVPAGARHPIIMLAEHVADTFIAMGWELA
MLBr_01401|M.leprae_Br4923          QAERDAAVLVTERIDVTLPSTRQPTGARHPITILAEHIADTFIAMGWELV
MMAR_2456|M.marinum_M               RAERDAAVLVAERIDVTLPSTRQPTGARHPITILAEHIADTFIAMGWELA
MUL_1635|M.ulcerans_Agy99           RAERDAAVLVAERIDVTLPSTRQPTGARHPITILAEHIADTFIAMGWELA
Mflv_3533|M.gilvum_PYR-GCK          RAERDAAVLVAERIDVTLPSTRQPVGARHPITILAERVADTFVAMGWELA
Mvan_3317|M.vanbaalenii_PYR-1       RAERDAEVLVAERIDVTLPSTRQPVGARHPITILAENVADTFVAMGWELA
MSMEG_3778|M.smegmatis_MC2_155      RAERDAAVLVAERIDVTLPSTRQPLGARHPITILAENIADTFVAMGWELA
TH_1591|M.thermoresistible__bu      RAERDAAALVAERIDVTLPSTRQPLGARHPITILAERIADTFVAMGWELA
MAV_3120|M.avium_104                RAERDAAVLVAERIDVTLPSTRQPVGARHPITILAEHIADTFIAMGWELA
MAB_2334|M.abscessus_ATCC_1997      RAERDAAVLVAERIDVTLPSTRQPLGARHPITILSENIADTFIAMGWEVA
                                    :***** .**:* ********* * ****** :*:*.:****:*****:.

Mb1676|M.bovis_AF2122/97            EGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQI
Rv1649|M.tuberculosis_H37Rv         EGPEVETEQFNFDALNFPADHPARGEQDTFYIAPEDSRQLLRTHTSPVQI
MLBr_01401|M.leprae_Br4923          DGPEVETEQFNFDALNFPADHPARSEQDTFYIAPDGSRQLLRTHTSPVQV
MMAR_2456|M.marinum_M               EGPEVETEQFNFDALNFPPDHPARSEQDTFYIAPEDSRQLLRTHTSPVQV
MUL_1635|M.ulcerans_Agy99           EGPEVETEQFNFDALNFPPDHPARSEQDTFYIAPEDSRQLLRTHTSPVQV
Mflv_3533|M.gilvum_PYR-GCK          EGPEVETEQFNFDALNFPPDHPARSEQDTFQVAPDGSRQVLRTHTSPVQI
Mvan_3317|M.vanbaalenii_PYR-1       EGPEVETEQFNFDALNFPPDHPARSEQDTFHIAPDGSRQVLRTHTSPVQV
MSMEG_3778|M.smegmatis_MC2_155      EGPEVETEQFNFDALNFPPDHPARSEQDTFQIAPDGSRQVLRTHTSPVQI
TH_1591|M.thermoresistible__bu      EGPEVESEQFNFDALNFPQDHPARSEQDTFHVAPEGSRQVLRTHTSPVQI
MAV_3120|M.avium_104                EGPEVEAEQFNFDALNFPADHPARSEQDTFYIAPEGSRQLLRTHTSPVQV
MAB_2334|M.abscessus_ATCC_1997      DGPEVETEHFNFDALNFLPDHPARSTQDTFYIAPEDSRQVLRTHTSPVQV
                                    :*****:*:********  *****. **** :**:.***:*********:

Mb1676|M.bovis_AF2122/97            RTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLR
Rv1649|M.tuberculosis_H37Rv         RTLLARELPVYIISIGRTFRTDELDATHTPIFHQVEGLAVDRGLSMAHLR
MLBr_01401|M.leprae_Br4923          RTLLERELPVYVISIGRAFRTDEVDATHTPVFHQVEGLAVDRGLSMAHLR
MMAR_2456|M.marinum_M               RTLLERELPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLR
MUL_1635|M.ulcerans_Agy99           RTLLERELPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDRGLTMAHLR
Mflv_3533|M.gilvum_PYR-GCK          RALLERELPVYIVSIGRTFRTDELDATHTPVFHQVEGLAVDKGLTMANLR
Mvan_3317|M.vanbaalenii_PYR-1       RTLLERELPVYVISIGRTFRTDELDATHTPVFHQVEGLAVDKGLTMAHLR
MSMEG_3778|M.smegmatis_MC2_155      RALLERDLPVYIISIGRTFRTDELDSTHTPVFHQVEGLAVDKGLTMAHLR
TH_1591|M.thermoresistible__bu      RALLERELPVYIISIGRTFRTDELDATHTPVFHQVEGLAVDKGLTMAHLR
MAV_3120|M.avium_104                RTLLARELPVYVISIGRTFRTDELDATHTPVFHQVEGLAVDRGLSMAHLR
MAB_2334|M.abscessus_ATCC_1997      RTLLARELPVYVISLGRAFRTDEIDATHLPAFHQVEGLAVDRGLTLANLK
                                    *:** *:****::*:**:*****:*:** * **********:**::*:*:

Mb1676|M.bovis_AF2122/97            GTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGADWVEWG
Rv1649|M.tuberculosis_H37Rv         GTLDAFARAEFGPSARTRIRPHFFPFTEPSAEVDVWFANKIGGAAWVEWG
MLBr_01401|M.leprae_Br4923          GTLDIFARAEFGPSTRTRIRPHFFPFTEPSAEVDVWFASKKDGADWVEWG
MMAR_2456|M.marinum_M               GTLDAFARSEFGPLARTRIRPHFFPFTEPSAEVDVWFANKKGGADWVEWG
MUL_1635|M.ulcerans_Agy99           GTLDAFARSEFGPLARTRIRPHFFPFTEPSAEVDVWFANKKGGADWVEWG
Mflv_3533|M.gilvum_PYR-GCK          GTLDAFARSEFGPQGRTRFRPHFFPFTEPSAEVDIWFPDKKGGPGWVEWG
Mvan_3317|M.vanbaalenii_PYR-1       GTLDAFARAQFGPQGRTRFRPHFFPFTEPSAEVDIWFPNKKGGPGWVEWG
MSMEG_3778|M.smegmatis_MC2_155      GTLDAFARAQFGPEGRTRFRPHFFPFTEPSAEVDIWFPGKKGGPGWVEWG
TH_1591|M.thermoresistible__bu      GTLDAFARSEFGPHGRTRFRPHFFPFTEPSAEVDVWFEGKKGGPGWVEWG
MAV_3120|M.avium_104                GTLDAFARAEFGPQARTRIRPHFFPFTEPSAEVDVWFVGKKGGAGWVEWG
MAB_2334|M.abscessus_ATCC_1997      GTLDAFARAMFGAQAHTRMRPHYFPFTEPSAEVDVWFENKKGGAGWVEWG
                                    **** ***: **.  :**:***:***********:** .* .*. *****

Mb1676|M.bovis_AF2122/97            GCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
Rv1649|M.tuberculosis_H37Rv         GCGMVHPNVLRATGIDPDLYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
MLBr_01401|M.leprae_Br4923          GCGMVHPNVLRATGIDPDIYSGFAFGMGLERTLQFRNSIPNMRDMVEGDV
MMAR_2456|M.marinum_M               GCGMVHPNVLRAAGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
MUL_1635|M.ulcerans_Agy99           GCGMVHPNVLRAAGIDPEVYSGFAFGMGLERSLQFRNGIPDMRDMVEGDV
Mflv_3533|M.gilvum_PYR-GCK          GCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
Mvan_3317|M.vanbaalenii_PYR-1       GCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
MSMEG_3778|M.smegmatis_MC2_155      GCGMVNPNVLRACGIDPEVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDV
TH_1591|M.thermoresistible__bu      GCGMVDPNVLRACGIDPDVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDI
MAV_3120|M.avium_104                GCGMVHPNVLRAAGIDPDVYSGFAFGMGLERTLQFRNGIPDMRDMVEGDM
MAB_2334|M.abscessus_ATCC_1997      GCGMVNPNVLRASGIDPGEYSGFAFGMGLERTLQFRNGLPDMRDMIEGDV
                                    *****.****** ****  ************:*****.:*:****:***:

Mb1676|M.bovis_AF2122/97            RFSLPFGVGA
Rv1649|M.tuberculosis_H37Rv         RFSLPFGVGA
MLBr_01401|M.leprae_Br4923          RFSLPFGVGA
MMAR_2456|M.marinum_M               RFSLPFGVGA
MUL_1635|M.ulcerans_Agy99           RFSLPFGVGA
Mflv_3533|M.gilvum_PYR-GCK          RFSLPFGVGA
Mvan_3317|M.vanbaalenii_PYR-1       RFSLPFGVGA
MSMEG_3778|M.smegmatis_MC2_155      RFSLPFGVGA
TH_1591|M.thermoresistible__bu      RFSLPFGVGL
MAV_3120|M.avium_104                RFSLPFGVGA
MAB_2334|M.abscessus_ATCC_1997      RFSLPFGVSA
                                    ********.