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GTSILDELEWRGLIAQSTDRDALAEALAEGPVTVYSGFDPTAPSLHAGHLIPLLTLRRFQQAGHRPIVLA GGATGMIGDPRDVGERTLNTADTVADWAGRIRGQLERFVEFDDSPTGAVVANNLSWTGELSAIEFLRDVG KHFSVNVMLDRDTVRRRLEGEGISYTEFSYMLLQANDYVELHQRYGCTLQVGGSDQWGNIIAGVRLVRQK AGASVHALTTPLVTDSEGKKFGKSTGGGSLWLDPEMTSPYAWYQYFINTADADVLPYLRWFTFLSADELV ELEQATTERPHERAAQRRLARELTNLVHGEAATAAVELASQALFGRAELGELDEPTLAAALREASVAQLA PGGPDSIIDLLVASGLSASKGAARRTVAEGGAYVNNVKIATDEWIPQASDFLHDRWLVLRRGKRNIAGIE RVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3294 | - | - | 100% (424) | tyrosyl-tRNA synthetase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1715 | tyrS | 0.0 | 80.66% (424) | tyrosyl-tRNA synthetase |
| M. gilvum PYR-GCK | Mflv_3513 | - | 0.0 | 90.24% (420) | tyrosyl-tRNA synthetase |
| M. tuberculosis H37Rv | Rv1689 | tyrS | 0.0 | 80.66% (424) | tyrosyl-tRNA synthetase |
| M. leprae Br4923 | MLBr_01352 | tyrS | 0.0 | 77.93% (426) | tyrosyl-tRNA synthetase |
| M. abscessus ATCC 19977 | MAB_2354 | - | 0.0 | 75.76% (425) | tyrosyl-tRNA synthetase (TyrS) |
| M. marinum M | MMAR_2488 | tyrS | 0.0 | 80.95% (420) | tyrosyl-tRNA synthase, TyrS |
| M. avium 104 | MAV_3082 | tyrS | 0.0 | 79.67% (423) | tyrosyl-tRNA synthetase |
| M. smegmatis MC2 155 | MSMEG_3758 | tyrS | 0.0 | 83.96% (424) | tyrosyl-tRNA synthetase |
| M. thermoresistible (build 8) | TH_1553 | tyrS | 1e-160 | 79.53% (337) | Probable Tyrosyl-tRNA synthase tyrS (TYRRS) |
| M. ulcerans Agy99 | MUL_1668 | tyrS | 0.0 | 80.71% (420) | tyrosyl-tRNA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3294|M.vanbaalenii_PYR-1 ------MGT------SILDELEWRGLIAQSTDRDALAEALAEGPVTVYSG
Mflv_3513|M.gilvum_PYR-GCK ------MSTP-----DILDDLEWRGLIAQSTDREALGEMLAAGPATVYSG
MSMEG_3758|M.smegmatis_MC2_155 MIVPVTSSAT-----GILDELDWRGLIAQSTDREALASDLAKGPMTVYSG
Mb1715|M.bovis_AF2122/97 ------MSG------MILDELSWRGLIAQSTDLDTLAAEAQRGPMTVYAG
Rv1689|M.tuberculosis_H37Rv ------MSG------MILDELSWRGLIAQSTDLDTLAAEAQRGPMTVYAG
MMAR_2488|M.marinum_M ------MSSNSSGSAGILDELGWRGLIAQSTDLDALAADVQRPPLTVYAG
MUL_1668|M.ulcerans_Agy99 ------MSSNSSGSAGILDELGWRGLIAQSTDLDALAADAQRPPLTVYAG
MAV_3082|M.avium_104 ------MSS------GILDELGWRGLIAQSTDLDALAAEAR--PMTVYAG
MLBr_01352|M.leprae_Br4923 ------MSS------SILNELGWRGLVAQSTDLDALADELRRGPMTVYAG
TH_1553|M.thermoresistible__bu --------------------------------------------------
MAB_2354|M.abscessus_ATCC_1997 --MASPTHDLRVSGSSILDELTWRGLIAQTTDRDALAADIAKGPISVYGG
Mvan_3294|M.vanbaalenii_PYR-1 FDPTAPSLHAGHLIPLLTLRRFQQAGHRPIVLAGGATGMIGDPRDVGERT
Mflv_3513|M.gilvum_PYR-GCK FDPTAPSLHAGHLIPLLTLRRFQQAGHRPIVLAGGATGMIGDPRDVGERT
MSMEG_3758|M.smegmatis_MC2_155 FDPTAPSLHAGHLVPLLTLRRFQQAGHRPIVLAGGATGMIGDPRDTGERT
Mb1715|M.bovis_AF2122/97 FDPTAPSLHAGHLVPLLTLRRFQRAGHRPIVLAGGATGMIGDPRDVGERS
Rv1689|M.tuberculosis_H37Rv FDPTAPSLHAGHLVPLLTLRRFQRAGHRPIVLAGGATGMIGDPRDVGERS
MMAR_2488|M.marinum_M FDPTAASLHAGHLVPLLALRRFQRAGHRPIVLAGGATGMIGDPRDIGERS
MUL_1668|M.ulcerans_Agy99 FDPTAASLHAGHLVPLLALRRFQRAGHRPIVLAGGATGMIGDPRDIGERS
MAV_3082|M.avium_104 FDPTAPSLHAGHLVPLLALRRFQRAGHRPIVLAGGATGMIGDPRDVGERT
MLBr_01352|M.leprae_Br4923 FDPTAPSLHVGHLVPLLVLRRFQRAGHRPIVLAGGATGMIGDPRDIGERT
TH_1553|M.thermoresistible__bu ---------------------------------------------VX--T
MAB_2354|M.abscessus_ATCC_1997 FDPTAASLHAGHLVPLLTLSRFQRAGHRPIVLAGGATGLIGDPRDTSERN
.
Mvan_3294|M.vanbaalenii_PYR-1 LNTADTVADWAGRIRGQLERFVEFDDSP---TGAVVANNLSWTGELSAIE
Mflv_3513|M.gilvum_PYR-GCK LNTADTVADWADRIRGQLERFVEFDDSE---TGAIVADNLTWTSELSAIE
MSMEG_3758|M.smegmatis_MC2_155 MNTEDTVADWADRIRGQLERFVEFDDSP---TGAIVENNLTWTGELSAIS
Mb1715|M.bovis_AF2122/97 LNEADTVAEWTERIRGQLERFVDFDDSP---MGAIVENNLEWTGSLSAIE
Rv1689|M.tuberculosis_H37Rv LNEADTVAEWTERIRGQLERFVDFDDSP---MGAIVENNLEWTGSLSAIE
MMAR_2488|M.marinum_M LNDADTVANWTERIRGQLERFVDFDGSP---TGAIVENNLEWTAAMSTVE
MUL_1668|M.ulcerans_Agy99 LNDADTVANWTERIRGQLERFVDFDGSP---TGAIVENNLEWTAAMSTVE
MAV_3082|M.avium_104 LNEADTVAEWTERIRGQLERFVDFDESA---TGAVVVNNLDWTRQLSAIE
MLBr_01352|M.leprae_Br4923 LNEAYTVAEWAERIRGQLERFVEFDDVAKSRNGAIVVNNLEWTSPMSAIE
TH_1553|M.thermoresistible__bu LQSADVVADWADRIKGQLERFVEFTDGP---TGAIVENNLTWTGGLTAIE
MAB_2354|M.abscessus_ATCC_1997 LHGTDVVAEWADRIRGQLERFVEFNDTP---TGAIVANNLEWTGQLTALE
:: .**:*: **:*******:* **:* :** ** ::::.
Mvan_3294|M.vanbaalenii_PYR-1 FLRDVGKHFSVNVMLDRDTVRRRLEGEGISYTEFSYMLLQANDYVELHQR
Mflv_3513|M.gilvum_PYR-GCK FLRDVGKHFSVNVMLDRDTVRRRLEGDGISYTEFSYMLLQANDYVELHQR
MSMEG_3758|M.smegmatis_MC2_155 FLRDIGKYFSVNVMLDRETVRRRLEGDGISYTEFSYMLLQANDYVELHQR
Mb1715|M.bovis_AF2122/97 FLRDIGKHFSVNVMLARDTIRRRLAGEGISYTEFSYLLLQANDYVELHRR
Rv1689|M.tuberculosis_H37Rv FLRDIGKHFSVNVMLARDTIRRRLAGEGISYTEFSYLLLQANDYVELHRR
MMAR_2488|M.marinum_M FLRDVGKHFSVNVMLDRDTIRRRLEGEGISYTEFSYMLLQANDYVELHRR
MUL_1668|M.ulcerans_Agy99 FLRDVGKHFSVNVMLDRDTIRRRLEGEGISYTEFSYMLLQANDYVELHRR
MAV_3082|M.avium_104 FLRDLGKHFSVNVMLDRDTVRRRLEGDGISYTEFSYMLLQANDYVELHRR
MLBr_01352|M.leprae_Br4923 FLRDVGKHFSINLMLDRDTIRRRLNGQGISYTEFSYMLLQANDYAELHQR
TH_1553|M.thermoresistible__bu FLRDIGKHFSVNVMLDRDTVRRRLEGEGISYTEFSYMLLQANDYVELYQR
MAB_2354|M.abscessus_ATCC_1997 FLRDLGKHFSVNVMLDRDTIRRRLEGDGISYTEFSYMLLQANDYVQLHRK
****:**:**:*:** *:*:**** *:*********:*******.:*:::
Mvan_3294|M.vanbaalenii_PYR-1 YGCTLQVGGSDQWGNIIAGVRLVRQKAGASVHALTTPLVTDSEGKKFGKS
Mflv_3513|M.gilvum_PYR-GCK YGCTLQVGGSDQWGNIIAGVRLVRQKAGAAVHAMTTPLVTDSEGKKFGKS
MSMEG_3758|M.smegmatis_MC2_155 HGCALQVGGSDQWGNIVAGVRLVRQKIGATVHAMTTPLVTDSEGKKFGKS
Mb1715|M.bovis_AF2122/97 HGCTLQIGGADQWGNIIAGVRLVRQKLGATVHALTVPLVTAADGTKFGKS
Rv1689|M.tuberculosis_H37Rv HGCTLQIGGADQWGNIIAGVRLVRQKLGATVHALTVPLVTAADGTKFGKS
MMAR_2488|M.marinum_M HGCTLQIGGSDQWGNIIAGVRLVRQKSGAAVHALTVPLVTAADGTKFGKS
MUL_1668|M.ulcerans_Agy99 HGCTLQIGGSDQWGNIIAGVRLVRQKSGAAVHALTVPLVTAADGTKFGKS
MAV_3082|M.avium_104 YGCVLQIGGSDQWGNIIAGVRLVRQKLGATVHALTVPLVTAADGTKFGKS
MLBr_01352|M.leprae_Br4923 HGCALQIGGSDQWGNIIAGVRLVRQKLGATVHALTVPLVTAADGAKLGKS
TH_1553|M.thermoresistible__bu YGCRLQIGGSDQWGNIVAGVRLVRQKLSATVHGLTVPLVTAADGTKFGKS
MAB_2354|M.abscessus_ATCC_1997 YGCSLQIGGSDQWGNIVAGVRLARQQDGASVHALTVPLVTAADGTKFGKS
:** **:**:******:*****.**: .*:**.:*.**** ::* *:***
Mvan_3294|M.vanbaalenii_PYR-1 TGGGSLWLDPEMTSPYAWYQYFINTADADVLPYLRWFTFLSADELVELEQ
Mflv_3513|M.gilvum_PYR-GCK TGGGSLWLDPEMTSPYAWYQYFINTADADVVPYLRWFTFLTAEELAELEL
MSMEG_3758|M.smegmatis_MC2_155 TGGGNLWLDPEMTSPYAWYQYFVNTADADVLGYLRWFTFLTPDELAELAD
Mb1715|M.bovis_AF2122/97 TGGGSLWLDPQMTSPYAWYQYFVNTADADVIRYLRWFTFLSADELAELEQ
Rv1689|M.tuberculosis_H37Rv TGGGSLWLDPQMTSPYAWYQYFVNTADADVIRYLRWFTFLSADELAELEQ
MMAR_2488|M.marinum_M TGGGSLWLDPEMTSPYAWYQYFVNTADADVIRYLRWFTFLVAEELTELEQ
MUL_1668|M.ulcerans_Agy99 TGGGSLWLDPEMTSPYAWYQYFVNTADADVIRYLRWFTFLVAEELTELEQ
MAV_3082|M.avium_104 TGGGSLWLDPALTTPYAWYQYFFNTADADVIRYLRWFTFLSADELGELER
MLBr_01352|M.leprae_Br4923 TGGGSLWLDPEMTSPYAWYQYFINTSDADVIRYLRWFTFLLPEELVELEQ
TH_1553|M.thermoresistible__bu TGGGNLWLDPDMTSPYTWYQYFINTADADVIRYLRWFTFLSAEELAELQE
MAB_2354|M.abscessus_ATCC_1997 TGGGNLWLDPEMTSPYAWYQYFINTADADVVRYLRWFTFLSAEEIGELET
****.***** :*:**:*****.**:****: ******** .:*: **
Mvan_3294|M.vanbaalenii_PYR-1 ATTERPHERAAQRRLARELTNLVHGEAATAAVELASQALFGRAELGELDE
Mflv_3513|M.gilvum_PYR-GCK ATAERPHERAAQRRLARELTNLVHGEAATAAVELASQALFGRGELADLDE
MSMEG_3758|M.smegmatis_MC2_155 ATENRPHERAAQRRLARELTTLVHGEGATKSVEYASRALFGRGELADLDE
Mb1715|M.bovis_AF2122/97 ATAQRPQQRAAQRRLASELTVLVHGEAATAAVEHASRALFGRGELARLDE
Rv1689|M.tuberculosis_H37Rv ATAQRPQQRAAQRRLASELTVLVHGEAATAAVEHASRALFGRGELARLDE
MMAR_2488|M.marinum_M ATAERPHQRAAQRRLAAELTTLVHGEAATEAVEHASRALFGHGELSRLDE
MUL_1668|M.ulcerans_Agy99 ATAERAHQRAAQRRLAAELTTLVHGEAATEAVEHASRALFGHGELSRLDE
MAV_3082|M.avium_104 ATAERPQQRAAQRRLARELTVLVHGEAATEAVEHASRALFGQGELERLDA
MLBr_01352|M.leprae_Br4923 TTVSRPQERAAQRRLATELTVLVHGAAATQAVEHASRALFGQGELARLDE
TH_1553|M.thermoresistible__bu ATEQRPHERAAQRRLARELTTLVHGQQATESAEHASRALFGRGELDRLDE
MAB_2354|M.abscessus_ATCC_1997 ATTERAHERAAQRRLAAEVTTLVHGESATLAVEHASGALFGRGDLDRLDE
:* .*.::******** *:* **** ** :.* ** ****:.:* **
Mvan_3294|M.vanbaalenii_PYR-1 PTLAAALREAS---VAQLAPGGPDSIIDLLVASGLSASKGAARRTVAEGG
Mflv_3513|M.gilvum_PYR-GCK NTLAGAVREAA---VAQLDPGGPDSIVDLLVATGLSASKGAARRTVAEGG
MSMEG_3758|M.smegmatis_MC2_155 STLSAALREAGNGQVAELAPGGPDSIVDLLVATGLSNSKGAARRTVAEGG
Mb1715|M.bovis_AF2122/97 ATLAAALRETT---VAELKPGSPDGIVDLLVASGLSASKGAARRTIHEGG
Rv1689|M.tuberculosis_H37Rv ATLAAALRETT---VAELKPGSPDGIVDLLVASGLSASKGAARRTIHEGG
MMAR_2488|M.marinum_M ATLGAALRETS---IAELEPGTPDGIVDLLVATGLSASKGAARRTIGEGG
MUL_1668|M.ulcerans_Agy99 ATLGAALRETS---IAELEPGTPDGIVDLLVATGLSASKGAARRTIGEGG
MAV_3082|M.avium_104 ATLAAALRETS---VAELKPGAPDGIVDLLVASGLSESRKAARRTLGEGG
MLBr_01352|M.leprae_Br4923 ATLATALRETV---VAELKPGNPDGIVDLLVASGLSPSRGAARRTIDEGG
TH_1553|M.thermoresistible__bu PTLAAALQEAS---VADLEPGAPDSIVDLLVASGLVQSRGAARRTVAEGG
MAB_2354|M.abscessus_ATCC_1997 GTLTAALTEAGNGEPARIADGEPDTIVDLLVSSGLSESKGAARRTVKEGG
** *: *: * : * ** *:****::** *: *****: ***
Mvan_3294|M.vanbaalenii_PYR-1 AYVNNVKIATDEWIPQASDFLHDRWLVLRRGKRNIAGIERVG------
Mflv_3513|M.gilvum_PYR-GCK VYVNNAKVTADDWVPQPSDFLHGRWLVLRRGKRNIAGVERVG------
MSMEG_3758|M.smegmatis_MC2_155 VYVNNARVESDEWVPQESDFLHEGWLVLRRGKRHIAGVRRVTASDQGK
Mb1715|M.bovis_AF2122/97 VSVNNIRVDNEEWVPQSSDFLHGRWLVLRRGKRSIAGVERIG------
Rv1689|M.tuberculosis_H37Rv VSVNNIRVDNEEWVPQSSDFLHGRWLVLRRGKRSIAGVERIG------
MMAR_2488|M.marinum_M VSVNNIRVETDEWVPQTSDFLHGRWLVLRRGKRNIAGVERVG------
MUL_1668|M.ulcerans_Agy99 VSVNNIRVETDEWVPQTSDFLHGRWLVLRRGKRNIAGVERVG------
MAV_3082|M.avium_104 VSVNNVRIDREDWAPQPSDFLHGKWLVLRRGKRTIAGVEKL-------
MLBr_01352|M.leprae_Br4923 VLVNNIRIQSEEWTPRTSDFLHGRWLVLRRGKRNIAGIERV-------
TH_1553|M.thermoresistible__bu AYVNNRRIEAEDWVPEPSDYLHGRWLVLRRGKRNIAGVRRVG------
MAB_2354|M.abscessus_ATCC_1997 VYVNNTRVDAEDWTPGDGDYLTGGWLVLRRGKRNIAGVQRLR------
. *** :: ::* * .*:* ********* ***:.::