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TAPHIVDPAGLLGEALSEASPDLMRSLLQTVINALLSADADAVVGAEWGQPTPGRRAQRNGYRHRGLDTR VGSIDVAVPKLRKGTYFPEWLLERRKRAESALITVVADCYLAGVSTRRMDKLVKTLGIDSLSKSQVSRMA TDLDEHVEQFRHRPLDSAGPFTFVAADALTMKVREGGRVVNGVVLLATGVNGDGHREVLGMRVVTSETGP AWNEFFADLVARGLAGVRLVTSDAHAGLREAIAANLPGAAWQRCRTHYAANLMSICPKSMWPAVKAMLHS VYDQPDAPAVAAQFDRLIDYVTDKLPAVAEHLSAAREDILAFTAFPKDVWTQIWSNNPAERLNKEIRRRT DAVGIFPNRDAIVRLVGAVLAEQNDEWAEGRRYLGLDILARCRLTTITNDNPEIGADDMPALTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3267 | - | - | 100% (415) | transposase, mutator type |
| M. vanbaalenii PYR-1 | Mvan_0454 | - | e-128 | 66.67% (339) | transposase, mutator type |
| M. vanbaalenii PYR-1 | Mvan_3590 | - | e-127 | 65.78% (339) | transposase, mutator type |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3142 | - | 1e-155 | 64.58% (415) | transposase |
| M. gilvum PYR-GCK | Mflv_2876 | - | 1e-154 | 65.53% (412) | transposase, mutator type |
| M. tuberculosis H37Rv | Rv3115 | - | 1e-155 | 64.58% (415) | transposase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4291 | - | 0.0 | 97.11% (415) | transposase, Mutator family protein |
| M. smegmatis MC2 155 | MSMEG_4154 | - | 8e-73 | 44.35% (336) | transposase, Mutator family protein |
| M. thermoresistible (build 8) | TH_2560 | - | 1e-127 | 65.49% (339) | PUTATIVE transposase, mutator type |
| M. ulcerans Agy99 | MUL_1849 | - | 2e-26 | 27.17% (346) | transposase for IS2606 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3267|M.vanbaalenii_PYR-1 -----------------------------------MTAPHIVDPAGLLGE
MAV_4291|M.avium_104 ---------MSVMDVKRPPRDPSSQPSTESSRSPTMTAPHIVDPAGLLGE
Mflv_2876|M.gilvum_PYR-GCK ------------------MILRETVQSHSSKGIDAMTTAHNIDLPTVLAE
TH_2560|M.thermoresistible__bu -----------------------------------MTTAHNIDLPTVLAE
Mb3142|M.bovis_AF2122/97 -----------------------------------MTSSHLIDTEQLLAD
Rv3115|M.tuberculosis_H37Rv -----------------------------------MTSSHLIDAEQLLAD
MSMEG_4154|M.smegmatis_MC2_155 -----------------------------------MTQDHSALLAQLDAL
MUL_1849|M.ulcerans_Agy99 MMTKTVVAVQPSQNHEDGAGAVAAIDVPSSRDVDELEVARELVRQAREAG
: : .
Mvan_3267|M.vanbaalenii_PYR-1 ALSEASPDLMRSLLQTVINALLSADADAVVGAEWGQPT-PGRRAQRNGYR
MAV_4291|M.avium_104 ALAEASPDLMRSLLQTVINALLSADADAVVGAEWGQPT-PGRRAQRNGYR
Mflv_2876|M.gilvum_PYR-GCK RLTTAHPDVLRELLATFIHTLMGAEADALCGAGYGERS-AERTNSRNGYR
TH_2560|M.thermoresistible__bu RLTTTHPDVLRELLATFIHTLMGAEADALCGAGYGERS-AERTNSRNGYR
Mb3142|M.bovis_AF2122/97 QLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERS-DERSNQRNGYR
Rv3115|M.tuberculosis_H37Rv QLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERS-DERSNQRNGYR
MSMEG_4154|M.smegmatis_MC2_155 KSADAG-AVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
MUL_1849|M.ulcerans_Agy99 VGLTGPGGLLKAMTKTVIEIALDEELSEHLGYDRHDRAGYGSGNSRNGTR
:: : : : : : * : : *** *
Mvan_3267|M.vanbaalenii_PYR-1 HRGLDTRVG-SIDVAVPKLRKGTYFPEWLLERRKRAESALITVVADCYLA
MAV_4291|M.avium_104 HRGLDTRVG-TIDVAVPKLRKGTYFPDWLLERRKRAESALITVVADCYLA
Mflv_2876|M.gilvum_PYR-GCK HRQFDTRAG-TLDLAIPKLRQGSYFPDWLLERRKRAERALTTVVATCYLL
TH_2560|M.thermoresistible__bu HRRFDTRAG-SLDLAIPKLRHGSYFPDWLLERRKRAERALTTVVATCYLL
Mb3142|M.bovis_AF2122/97 HRDFDTRAA-TIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLL
Rv3115|M.tuberculosis_H37Rv HRDFDTRAA-TIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLL
MSMEG_4154|M.smegmatis_MC2_155 PKTVSTTAG-DVEVQIPKLRAGSFFPS-LLERRRRIDRALHAVIMEAYVH
MUL_1849|M.ulcerans_Agy99 SKTVLTDACGSIEIDVPRDRAGTFEPK-IVEKRQRRLTDVDEVVLSLYAR
: . * . ::: :*: * *:: *. ::::*:* : *: *
Mvan_3267|M.vanbaalenii_PYR-1 GVSTRRMDKLVKTLGIDS-LSKSQVSRMATDLDEHVEQFRHRPLDSAGPF
MAV_4291|M.avium_104 GVSTRRMDKLVKTLGIDS-LSKSQVSRMATDLDEHVEAFRHRPLDSAGPF
Mflv_2876|M.gilvum_PYR-GCK GVSTRRMDKLVETLGITS-LSKSQVSVMAKELDAAVEAFRTRPLD-AGPY
TH_2560|M.thermoresistible__bu GVSTRRMDKLVETLGITS-LSKSQVSVMATELDTAVEAFRTRPLD-AGPY
Mb3142|M.bovis_AF2122/97 GVSTRRMERLVETLGVTK-LSKSQVSIMAKELDEAVEAFRTRPLD-AGPY
Rv3115|M.tuberculosis_H37Rv GVSTRRMERLVETLGVTK-LSKSQVSIMAKELDEAVEAFRTRPLD-AGPY
MSMEG_4154|M.smegmatis_MC2_155 GVSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLN-HTSF
MUL_1849|M.ulcerans_Agy99 GLTTEEISAHFAHIYDAA-VSKDTVSRITDRVLEEMTAWHTRPLE--RVY
*::*. :. . : :**. ** : : : :: *.*: :
Mvan_3267|M.vanbaalenii_PYR-1 TFVAADALTMKVREGGRVVNGVVLLATGVNGDGHREVLGMRVV--TSETG
MAV_4291|M.avium_104 TFVAADALTMKVREGGRVVNGVVLLATGVNGDGHREVLGMRVV--TSETG
Mflv_2876|M.gilvum_PYR-GCK TFVAADALVLKVREAGRVVNVHALIAVGVNAEGYREILGIDVT--TAEDG
TH_2560|M.thermoresistible__bu TFVAADALVLKVREQGRVVNVHALIATGVNAEGYREILGVDVT--TAEDG
Mb3142|M.bovis_AF2122/97 TFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVT--SAEDG
Rv3115|M.tuberculosis_H37Rv TFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVT--SAEDG
MSMEG_4154|M.smegmatis_MC2_155 PYVFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVG--DSESF
MUL_1849|M.ulcerans_Agy99 AAVFIDALHVKIRD-GQVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESA
. : ** *:* .:* *.**. * *::** . .*
Mvan_3267|M.vanbaalenii_PYR-1 PAWNEFFADLVARGLAGVRLVTSDAHAGLREAIAANLPGAAWQRCRTHYA
MAV_4291|M.avium_104 PAWNEFFADLVARGLAGVRLVTSDAHAGLREAIAANLPGAAWQRCRTHYA
Mflv_2876|M.gilvum_PYR-GCK AGWLTFWRSLTARGLSGVKLVTSDAHAGLVAAIGATLPGAAWQRCRTHYT
TH_2560|M.thermoresistible__bu AGWLAFWRSLTARGLSGVKLVTSDAHTGLVAAIGATLPGATWQRCRTHYT
Mb3142|M.bovis_AF2122/97 AGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYA
Rv3115|M.tuberculosis_H37Rv AGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYA
MSMEG_4154|M.smegmatis_MC2_155 EFWREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFM
MUL_1849|M.ulcerans_Agy99 KYWLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLI
* . .* **::.: :: .*. ** ::. :. : * * *
Mvan_3267|M.vanbaalenii_PYR-1 ANLMSICPKSMWPAVKAMLHSVYDQPDAPAVAAQFDRLIDYVTDKLPAVA
MAV_4291|M.avium_104 ANLMSICPKSMWPAVKAMLHSVYDQPDAPAVAAQFDRLIDYVTDKLPAVA
Mflv_2876|M.gilvum_PYR-GCK TNLMSVTPKSSWPWVRTLLHSVFDQPDAESVAAQYDRIIDALSDKLPNVA
TH_2560|M.thermoresistible__bu TNLMAVTPKSSWPWVRTLLHSVFDQPDAESVAAQYDRIIDALVDKLPKVA
Mb3142|M.bovis_AF2122/97 ANLMAATPKPSWPWVRTLLHSIYDQPDAESVVAQYDRVLDALTDKLPAVA
Rv3115|M.tuberculosis_H37Rv ANLMAATPKPSWPWVRTLLHSIYDQPDAESVVAQYDRVLDALTDKLPAVA
MSMEG_4154|M.smegmatis_MC2_155 RNLHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVADTLAASFPKVA
MUL_1849|M.ulcerans_Agy99 RGTFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDTEWGHRYPAAI
. . : ::.:: :. .. * . * .
Mvan_3267|M.vanbaalenii_PYR-1 EHLSAAREDILAFTAFPKDVWTQIWSNNPAERLNKEIRRRTDAVGIFPNR
MAV_4291|M.avium_104 DHLATAREDILAFTAFPKDVWSQIWSNNPAERLNKEIRRRTDAVGIFPNR
Mflv_2876|M.gilvum_PYR-GCK DHLEAARPDLLAFTAFPKQIWRQIWSNNPQERLNKEIRRRTDVVGIFPDR
TH_2560|M.thermoresistible__bu DHLQAARPDLLAFTAFPKQIWRQIWSNNP---------------------
Mb3142|M.bovis_AF2122/97 EHLDTARTDLLAFTAFPKQIWRQIWSNNPQERLNREVRRRTDVVGIFPDR
Rv3115|M.tuberculosis_H37Rv EHLDTARTDLLAFTAFPKQIWRQIWSNNPQERLNREVRRRTDVVGIFPDR
MSMEG_4154|M.smegmatis_MC2_155 AMMDEAKADVLAFTAFPRTHWQKIWSNNP-------IVICSAAVSVFY--
MUL_1849|M.ulcerans_Agy99 RLWRTAWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTE
* :.:.* : * *.*.
Mvan_3267|M.vanbaalenii_PYR-1 DAIVRLVGAVLAEQNDEWAEGRRYLGLDILARCRLTTITNDNPEIGADDM
MAV_4291|M.avium_104 DAIVRLVGAVLAEQNDEWAEGRRYLGLDILTRCRLTTITDDNPDIGANDM
Mflv_2876|M.gilvum_PYR-GCK AALIRLVGAVLAEQHDEWAESRRYLGLDVLSKSRTVND---TPTEQEATP
TH_2560|M.thermoresistible__bu ---------------------------------RSVN----RPSHDTIMG
Mb3142|M.bovis_AF2122/97 ASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTSTEEPAKQQTTN
Rv3115|M.tuberculosis_H37Rv ASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTSTEEPAKQQTTN
MSMEG_4154|M.smegmatis_MC2_155 ----------VDHEGSEWSVLRSGCG---YLQPSMKQILEGRCACCEGGF
MUL_1849|M.ulcerans_Agy99 QSALKCLYLVTRSLDPTGTGQKRWTMRWKPALNAFAITFADRMPGSETT-
Mvan_3267|M.vanbaalenii_PYR-1 PALTA-
MAV_4291|M.avium_104 PALTA-
Mflv_2876|M.gilvum_PYR-GCK AALPA-
TH_2560|M.thermoresistible__bu AA----
Mb3142|M.bovis_AF2122/97 TPALTT
Rv3115|M.tuberculosis_H37Rv TPALTT
MSMEG_4154|M.smegmatis_MC2_155 TALVA-
MUL_1849|M.ulcerans_Agy99 ------