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AGDHEVAHLAGGHLAGTDSHLESPTYLQKRQLRTGSAGWLLLAGLGVSYVISGDYSGWNFGLARGGFGGL AIAAVVIAAMYLALVLSMAELSSALPAAGGGYTFARRALGPWGGFATGTAVLIEYSIAPAAIATFIGAYV QSLGLFGIRNGWWVYLTIYALFIGIHLSGVGEALKVMFIITGVALVGLVVFAIAAVGHFRLANLVDITPS DAVGASAFLPHGYLGVWSALPFAIWFFLAVEGVPLAAEETADPARNVPRGITAAFSVLVLTCAAVLLLAT GAGGAAAMSSSGNPLVAALGPTVAATVVNYIGLAGLVASFFSIIYAYSRQLFALSRAGYLPTALSITNSR KAPTLALIVPGVIGFALSVTGEGDLLLNMAVFGATLSYVLMMISHIVLRRRAADMARPYRTPGGIATSGF ALLVAATALIATFLVDTVAALCCLGVFCAFILYFALYSRHQLVANSPDEELAGSQDFESELQ*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0665 | - | - | 100% (483) | ethanolamine transporter |
| M. marinum M | MMAR_2052 | - | 3e-25 | 27.82% (363) | amino acid transporter |
| M. marinum M | MMAR_3621 | rocE | 5e-25 | 25.58% (430) | cationic amino acid transport integral membrane protein RocE |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2347c | rocE | 1e-26 | 25.48% (420) | cationic amino acid transport integral membrane protein RocE |
| M. gilvum PYR-GCK | Mflv_3442 | - | 0.0 | 75.91% (469) | ethanolamine transproter |
| M. tuberculosis H37Rv | Rv2320c | rocE | 1e-26 | 25.48% (420) | cationic amino acid transport integral membrane protein RocE |
| M. leprae Br4923 | MLBr_01305 | ansP2 | 2e-14 | 22.30% (426) | putative L-asparagine permease |
| M. abscessus ATCC 19977 | MAB_2791c | - | 0.0 | 78.92% (465) | putative ethanolamine permease |
| M. avium 104 | MAV_4216 | - | 8e-26 | 27.03% (381) | cationic amino acid transporter |
| M. smegmatis MC2 155 | MSMEG_1552 | eat | 0.0 | 75.74% (470) | ethanolamine permease |
| M. thermoresistible (build 8) | TH_0471 | - | 2e-28 | 27.65% (405) | POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE |
| M. ulcerans Agy99 | MUL_1244 | rocE | 9e-26 | 25.58% (430) | cationic amino acid transport integral membrane protein RocE |
| M. vanbaalenii PYR-1 | Mvan_3196 | - | 0.0 | 78.37% (467) | ethanolamine transproter |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2347c|M.bovis_AF2122/97 ---MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGA
Rv2320c|M.tuberculosis_H37Rv ---MPTTSMSLRELMLRRRPVSGAPVASGASGNLKRSFGTFQLTMFGVGA
MUL_1244|M.ulcerans_Agy99 ---MPATSIRLREQMLRRRPAGGAPVAEGAAGSLKRSFGTFELTMFGVGS
MAV_4216|M.avium_104 ------MASRWRTKSVEQSIAD----TDEPDTRLRKDLTWWDLVVFGVAV
TH_0471|M.thermoresistible__bu ------MTDRLRVKSVEQSIAD----TDEPDSRLRKDLSWWDLTVFGVSV
MAB_2791c|M.abscessus_ATCC_199 ----------MATTKHGLIEEHLESADYLRKRQLRSGSAGWLLLAGLGVS
MSMEG_1552|M.smegmatis_MC2_155 ----------MAG-----VEEHLESADYLQKRQLKSGSAGWVLLAGLGVS
Mflv_3442|M.gilvum_PYR-GCK ----------MRG-----VEEHRESESYLQKRQLKSGSAGWILLAGLGVS
Mvan_3196|M.vanbaalenii_PYR-1 MSGEAHSTHTTRG-----VEAHRESDAYLQKRQLKKGSAGWILLAGLGIS
MMAR_0665|M.marinum_M -MAGDHEVAHLAGGHLAGTDSHLESPTYLQKRQLRTGSAGWLLLAGLGVS
MLBr_01305|M.leprae_Br4923 --------MATLAESPEPKSGASRAGVLGEEAGYHKGLKPRQLQMIGIGG
: . *
Mb2347c|M.bovis_AF2122/97 TIGTGIFFVLAQAVP-EAGPGVIVSFIIAGIAAGLAAICYAELASAVPIS
Rv2320c|M.tuberculosis_H37Rv TIGTGIFFVLAQAVP-EAGPGVIVSFIIAGIAAGLAAICYAELASAVPIS
MUL_1244|M.ulcerans_Agy99 TVGTGIFFVLAEAVP-EAGPAVIVSFIIAGVAAGLAAICCAELASAVPVS
MAV_4216|M.avium_104 VIGAGIFTVTASTTGDITGPAIWVSFVIAAGTCALAALCYAEFASTLPVA
TH_0471|M.thermoresistible__bu VIGAGIFTVTASTAGNITGPAISVSFIIAAIACGLAALCYAEFASTVPVA
MAB_2791c|M.abscessus_ATCC_199 YVVSGDYSGWNFGLRQGGFGGLALATVVIAGMYLALVLGMAELSSALPTA
MSMEG_1552|M.smegmatis_MC2_155 YVISGDYSGWNFGLEQGGFGGLAIAAIIIAGMYLALVLGMAELSSALPAA
Mflv_3442|M.gilvum_PYR-GCK YVISGDYSGWNFGLGQGGFGGLAIAAVIIAAMYLAMVLGMAEMSSALPAA
Mvan_3196|M.vanbaalenii_PYR-1 YVVSGDYSGWNFGLGQGGFGGLAIAAVVIAAMYLAMVLGMAEMSSALPAA
MMAR_0665|M.marinum_M YVISGDYSGWNFGLARGGFGGLAIAAVVIAAMYLALVLSMAELSSALPAA
MLBr_01305|M.leprae_Br4923 AIGTGLFLGAGGRLA-KAGPGLFLVYAVCGVFVFLILRALGELVLHRPSS
: :* : .: : : . .*: * :
Mb2347c|M.bovis_AF2122/97 GSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLF
Rv2320c|M.tuberculosis_H37Rv GSAYSYAYTTLGEAVAMVVAACLLLEYGVATAAVAVGWSGYVNKLLSNLF
MUL_1244|M.ulcerans_Agy99 GSSYSYAYATLGEAVAMGVASCLLLEYGVATAAVAVGLSGYVNKLLHNVF
MAV_4216|M.avium_104 GSAYTFSYATFGEFLAWIIGWNLLLELAIGAAVVAKGWSSYLG----TVF
TH_0471|M.thermoresistible__bu GSAYTFSYATFGEFVAWIIGWDLILEFSVAAAVVAKGWSSYLG----EVF
MAB_2791c|M.abscessus_ATCC_199 GGGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVQS--LGLF
MSMEG_1552|M.smegmatis_MC2_155 GGGYTFARRALGPWGGFATGTAILIEYAIAPAAIATFIGAYVES--LGLF
Mflv_3442|M.gilvum_PYR-GCK GGGYTFARRALGPWGGFATGTAILIEYAIAPAAIATFIGAYVES--LNLF
Mvan_3196|M.vanbaalenii_PYR-1 GGGYTFARRALGPWGGFATGTAILIEYSIAPAAIATFIGAYVES--LGLF
MMAR_0665|M.marinum_M GGGYTFARRALGPWGGFATGTAVLIEYSIAPAAIATFIGAYVQS--LGLF
MLBr_01305|M.leprae_Br4923 GSFVSYAREFFGEKAAYVVGWLYFLDWAMTAIVDTTAIATYLHR--WTIF
*. ::: :* . . ::: .: . . : . *: :*
Mb2347c|M.bovis_AF2122/97 GFQMPHVLSAAPWDTHPG----WVNLPAVILIGLCALLLIRGASESARVN
Rv2320c|M.tuberculosis_H37Rv GFQMPHVLSAAPWDTHPG----WVNLPAVILIGLCALLLIRGASESARVN
MUL_1244|M.ulcerans_Agy99 GFQLPQALSEAPWDERPGEAAGYLNLPAIILIGLCALLLIRGVSESAKVN
MAV_4216|M.avium_104 GFSGGTVKFGAAQ----------LDWGALVIVGGVATLIALGTKLSSRFS
TH_0471|M.thermoresistible__bu EFAGATTRLGPIT----------LDWGALLIIGFVTVLLATGTKLSANVS
MAB_2791c|M.abscessus_ATCC_199 GITNG-------------------WWVYLAAYAFFIGIHLSGVGEALKVM
MSMEG_1552|M.smegmatis_MC2_155 GITAG-------------------WWIYLAAFAIFIGIHLAGVGEALKVM
Mflv_3442|M.gilvum_PYR-GCK GITDG-------------------WWVYLAAYALFIGIHLAGVGEALKVM
Mvan_3196|M.vanbaalenii_PYR-1 GITDG-------------------WWVYLAAYAIFIGIHLSGVGEALKVM
MMAR_0665|M.marinum_M GIRNG-------------------WWVYLTIYALFIGIHLSGVGEALKVM
MLBr_01305|M.leprae_Br4923 TALPQ-------------------WTLALLALAVVLVMNLISVEWFGELE
: . : .. ..
Mb2347c|M.bovis_AF2122/97 AIMVLIKLGVLGMFMIIAFSAYSADHLKDFVP------------------
Rv2320c|M.tuberculosis_H37Rv AIMVLIKLGVLGMFMIIAFSAYSADHLKDFVP------------------
MUL_1244|M.ulcerans_Agy99 AIMVLIKLGVLGMFVILALTAYDTNHLKDFAP------------------
MAV_4216|M.avium_104 AVITGIKVSVVVFVVVVGVFYIKRANYSPFIPKPEAGGQA-KGIDQSVLS
TH_0471|M.thermoresistible__bu LAITVIKVGVVLLVVIVGAFFIKAANYTPFIPPAEAGGEAGRSLDQSLFS
MAB_2791c|M.abscessus_ATCC_199 FVITAIALVGLLIFAIAAAGHFDLHNLTNIAADESAAGSS----------
MSMEG_1552|M.smegmatis_MC2_155 FVITAIAMVGLVIFALAAIGQFDASNLTNIAPDAGAAGAS----------
Mflv_3442|M.gilvum_PYR-GCK FVITVIALIGIVVFAVAAIPQFDSANLTDIAVTD-AAGAS----------
Mvan_3196|M.vanbaalenii_PYR-1 FVITAIALVGLVVFAVAAIPHFDSTNLTDIAVTD-AAGAS----------
MMAR_0665|M.marinum_M FIITGVALVGLVVFAIAAVGHFRLANLVDITPSD-AVGAS----------
MLBr_01305|M.leprae_Br4923 FWAALIKVCALMAFLVVGTIFLGGRYPVDGHNTGLSLWTSHG--------
. : : : . : .
Mb2347c|M.bovis_AF2122/97 ---------FGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQKTMPRAL
Rv2320c|M.tuberculosis_H37Rv ---------FGVAGIGSAAGTIFFSYIGLDAVSTAGDEVKDPQKTMPRAL
MUL_1244|M.ulcerans_Agy99 ---------FGVAGVGAAAGTIFFSFIGLDAVSTAGEEVRNPQQSVPRAL
MAV_4216|M.avium_104 LLTGAHTSHYGWYGVLAGASIVFFAFIGFDIVATMAEETKHPQRDVPRGI
TH_0471|M.thermoresistible__bu LITGAEGSSYGWYGLLAGASIVFFAFIGFDIIATTAEETKNPQRDVARGI
MAB_2791c|M.abscessus_ATCC_199 -----SILPHGYLGIWAAIPFAIWFFLAVEGVPLAAEETAHPERNVPRGI
MSMEG_1552|M.smegmatis_MC2_155 -----SFLPHGYLGIWAAIPFAIWFFLAIEGVPLAAEETVNPERNVPRGI
Mflv_3442|M.gilvum_PYR-GCK -----PLLPFGLLGIWAAIPFAIWFFLAIEGVPLAAEEAEEPERNMPKGI
Mvan_3196|M.vanbaalenii_PYR-1 -----ALLPFGLLGIWAAIPFAIWFFLAIEGVPLAAEETAEPERNVPKGI
MMAR_0665|M.marinum_M -----AFLPHGYLGVWSALPFAIWFFLAVEGVPLAAEETADPARNVPRGI
MLBr_01305|M.leprae_Br4923 -----GLFPTGVAPLIVVSSGVMFAYAAVELVGTAAGETVEPKKIMPRAI
* : :: : ..: : . *. .* : :.:.:
Mb2347c|M.bovis_AF2122/97 IAALVVVTGVYVLVALAALGTQPWQDFAEQETAGLAIILDNVTHG--EWA
Rv2320c|M.tuberculosis_H37Rv IAALVVVTGVYVLVALAALGTQPWQDFAEQETAGLAIILDNVTHG--EWA
MUL_1244|M.ulcerans_Agy99 IAALFVVTGVYVLVAFAALGTQPWQMFAGQEEAGLATILDNVTHS--AWA
MAV_4216|M.avium_104 LASLGIVTLLYVAVAVVLSGMVSYTQLKTMPGRGQANLATAFTANGIHWA
TH_0471|M.thermoresistible__bu MATLGIVTVLYVAVSLVLTGMVHYTELRAAG--ENANLATAFAANGIDWA
MAB_2791c|M.abscessus_ATCC_199 IAAIAVLLVTCATALVLTTGAGGAEQMSDSG----NPLVEALGHG---TA
MSMEG_1552|M.smegmatis_MC2_155 IAGMGVLLVTCVVVLFLVTGAGGAEQMSTSG----NPLVEALGDG---TA
Mflv_3442|M.gilvum_PYR-GCK IAGMAVLLVTCVTVLVLTTGAGGAAAMSESG----NPLVEALGDS---TW
Mvan_3196|M.vanbaalenii_PYR-1 IAGMAVLLVTCVTVLVLTTGAGGAAAMSESG----NPLVEALGDS---GW
MMAR_0665|M.marinum_M TAAFSVLVLTCAAVLLLATGAGGAAAMSSSG----NPLVAALGPT---VA
MLBr_01305|M.leprae_Br4923 NSVIARIAIFYVGSVILLALLLPYSAFKASE----SPFVTFFSKVGFYGA
: : : . . : : .
Mb2347c|M.bovis_AF2122/97 STILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTP
Rv2320c|M.tuberculosis_H37Rv STILAAGAVVSIFTVTLVTMYGQTRILFAMGRDGLLPARFAKVNPRTMTP
MUL_1244|M.ulcerans_Agy99 STVLAMGAVISIFTVTLVTMYGQTRILFAMGRDGLLPARFAAVHPRFQTP
MAV_4216|M.avium_104 SKIISIGALAGLTTVVMVLMLGQCRVLFAMARDGLLPRALAKTGSR-GTP
TH_0471|M.thermoresistible__bu AKVISIGALAGLTTVVIVLVLGQTRVLFAMSRDGLLPRPLSKTGPR-GTP
MAB_2791c|M.abscessus_ATCC_199 AKLVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTVLSVTNSR-KAP
MSMEG_1552|M.smegmatis_MC2_155 AKVVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPRALSVTNKR-KAP
Mflv_3442|M.gilvum_PYR-GCK ATVVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPKILSVTNRR-KAP
Mvan_3196|M.vanbaalenii_PYR-1 AKVVNYIGLAGLIASFFSIIYAYSRQLFALSRAGYLPTVLSVTNSR-KAP
MMAR_0665|M.marinum_M ATVVNYIGLAGLVASFFSIIYAYSRQLFALSRAGYLPTALSITNSR-KAP
MLBr_01305|M.leprae_Br4923 GDLMNIVVLTAALSSLNAGLYATGRVMHSIAINGSGPKFTARMSKN-GVP
. :: : . : : . * :.::. * * : . .*
Mb2347c|M.bovis_AF2122/97 VHNTVIVAIFASTLAAFIPLD------SLADMVSIGTLTAFSVVAVGVIV
Rv2320c|M.tuberculosis_H37Rv VHNTVIVAIFASTLAAFIPLD------SLADMVSIGTLTAFSVVAVGVIV
MUL_1244|M.ulcerans_Agy99 VSNTVVVAIAAAVLAALVPLN------RLADMVSIGTLTAFIVVSVGVII
MAV_4216|M.avium_104 VRITVLVALVVAVTASVFPIT------KLEEMVNVGTLFAFVLVSAGVMV
TH_0471|M.thermoresistible__bu VRITVLVGALVAIAASVFPVG------NLEEMVNIGTLFAFALVSAGVIV
MAB_2791c|M.abscessus_ATCC_199 TLALIVPGVVGFALSLTGHGD------LLLNMAVFGAALSYVLMMVSHIT
MSMEG_1552|M.smegmatis_MC2_155 TLALVIPGIIGFLLSLTGQGD------LLLNMAVFGAALSYVLMMVSHIT
Mflv_3442|M.gilvum_PYR-GCK TLALLVPGVIGFCLSLIGQGA------LLLNMAVFGAAVSYVLMMVSHIV
Mvan_3196|M.vanbaalenii_PYR-1 TLALIVPGVIGFLLSLIGQGA------LLLNMAVFGAALSYVLMMVSHIV
MMAR_0665|M.marinum_M TLALIVPGVIGFALSVTGEGD------LLLNMAVFGATLSYVLMMISHIV
MLBr_01305|M.leprae_Br4923 YGGILLAAVICLCGVALNAFNPGQAFEIVLSVAALGIIAGWGTIVLCQLR
:: . : .:. .* .: : :
Mb2347c|M.bovis_AF2122/97 LRVREPD--LPRG-FKVPGYPVTPVLSVLACGYILASLHWYTWLAFSGWV
Rv2320c|M.tuberculosis_H37Rv LRVREPD--LPRG-FKVPGYPVTPVLSVLACGYILASLHWYTWLAFSGWV
MUL_1244|M.ulcerans_Agy99 LRVREPA--LPRG-FWVPGYPVTPILSILACGYLLYSLHWYTWIAFGGWV
MAV_4216|M.avium_104 LRRTRPD--LERG-FKAPWVPVLPIASIGACVWLMLNLTALTWVRFGIWL
TH_0471|M.thermoresistible__bu LRRTRPD--LKRG-FRVPFVPWLPLAAIAACLWLMLNLTGLTWVRFLGWM
MAB_2791c|M.abscessus_ATCC_199 LRVREPN--MPRP-YRTPGGIVTTSFALIVAVLAVAATFLVNPVAAGLCL
MSMEG_1552|M.smegmatis_MC2_155 LRVREPN--MPRP-YRTPGGAVTTGFALVVACFAVIATFLVNPIAAGLCL
Mflv_3442|M.gilvum_PYR-GCK LRRRAPE--MHRP-YRTPGGVFTTGFALVIAVLAVIATFLVDYVAALGCL
Mvan_3196|M.vanbaalenii_PYR-1 LRRREPD--MPRP-YRTPGGVVTTGFALVIAVLAVIATFLVDSVAALCCL
MMAR_0665|M.marinum_M LRRRAAD--MARP-YRTPGGIATSGFALLVAATALIATFLVDTVAALCCL
MLBr_01305|M.leprae_Br4923 LHKMAKAGIMRRPRFRMPLAPYSGYLTLAFLFAVLVVMAFDKPIGTWTVA
*: : * : * :: : :
Mb2347c|M.bovis_AF2122/97 AVAVIFYLMWGRHHSALNEEVP----------------------------
Rv2320c|M.tuberculosis_H37Rv AVAVIFYLMWGRHHSALNEEVP----------------------------
MUL_1244|M.ulcerans_Agy99 GIALIFYLFWGRHHSRLNAPALHDNPTGEER-------------------
MAV_4216|M.avium_104 VVGTAIYAGYGYWHSVQGRRDAGEPDRSDALAADPNSPVP----------
TH_0471|M.thermoresistible__bu ALGLVLYFFYGRHHSMLGR---GMTDISARRTG-----------------
MAB_2791c|M.abscessus_ATCC_199 AVFAAFMAYFALYSRHRLVANSPDEEFAILAEAESELT------------
MSMEG_1552|M.smegmatis_MC2_155 LVFAGFMLYFAVYSRHRLVANSPDEEFAMLAEAENELK------------
Mflv_3442|M.gilvum_PYR-GCK LVFAAFMAYFGLYSRHHLVANSPDEEFAALASAEDELR------------
Mvan_3196|M.vanbaalenii_PYR-1 VVFAAFMAYFGIYSRHHLVANSPDEEFAALAAAEGELK------------
MMAR_0665|M.marinum_M GVFCAFILYFALYSRHQLVANSPDEELAGSQDFESELQ------------
MLBr_01305|M.leprae_Br4923 SLIVIVPALIAGWYSIRKRVMTIARERMGYTGPFPAIANPPVQPSERSHS
: . .
Mb2347c|M.bovis_AF2122/97 ---
Rv2320c|M.tuberculosis_H37Rv ---
MUL_1244|M.ulcerans_Agy99 ---
MAV_4216|M.avium_104 ---
TH_0471|M.thermoresistible__bu ---
MAB_2791c|M.abscessus_ATCC_199 ---
MSMEG_1552|M.smegmatis_MC2_155 ---
Mflv_3442|M.gilvum_PYR-GCK ---
Mvan_3196|M.vanbaalenii_PYR-1 ---
MMAR_0665|M.marinum_M ---
MLBr_01305|M.leprae_Br4923 QNP