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MDVLITGCDTDLGRTIAESFSEAGHKVLVGGRRRDELEVLAKELDVDALVFDNTDPASVAALHGQVPAHL DTIINMPAPTWTVGDPRTYTLADHAAEWRGLFDAGLVASVLTVQVLGDHMRSGGSIINVIPDFVRDGSAA AAVKAAVSDWTAGQADQFGVRGITVNAVAVGRGVEPGYDGLGSTPPSVAAEISRLSLFLTTPAARHITGQ TLHVTHGALANFG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3076 | - | - | 100% (223) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0325 | - | 2e-10 | 27.42% (248) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4921 | - | 1e-09 | 27.46% (244) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1887c | - | 5e-78 | 61.88% (223) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_3346 | - | 1e-107 | 83.78% (222) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1856c | - | 5e-78 | 61.88% (223) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_02059 | - | 4e-73 | 59.91% (222) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2432c | - | 1e-57 | 50.00% (224) | short chain dehydrogenase |
| M. marinum M | MMAR_2730 | - | 2e-80 | 63.96% (222) | oxidoreductase |
| M. avium 104 | MAV_2864 | - | 9e-79 | 60.81% (222) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3619 | - | 4e-84 | 65.30% (219) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_1175 | - | 2e-80 | 64.13% (223) | POSSIBLE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_3023 | - | 2e-80 | 63.96% (222) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1887c|M.bovis_AF2122/97 MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDA
Rv1856c|M.tuberculosis_H37Rv MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDA
MLBr_02059|M.leprae_Br4923 MAVDVLVTGGNTDLGRTIAEGFRNDGHKVTLVGPRRADLEVVAKELDVDT
MMAR_2730|M.marinum_M MAVEVLVTGGDTDLGRTVAEGFRDDGHKVTLVGARRDDLEVVAKELDADA
MUL_3023|M.ulcerans_Agy99 MAVEVLVTGGDTDLGRTVAEGFRDDGHKVTLVGARRDDLEVVAKELDADA
MAV_2864|M.avium_104 --MEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARKSDLEIAAKELEAEA
MSMEG_3619|M.smegmatis_MC2_155 -MAEVLVTGGDTELGRAIAQGFRDAGHNVVIAGARRDDLEVAAKELDIES
Mvan_3076|M.vanbaalenii_PYR-1 --MDVLITGCDTDLGRTIAESFSEAGHKVLVGGRRRDELEVLAKELDVDA
Mflv_3346|M.gilvum_PYR-GCK --MDVLVTGCDTDLGRTIAEGFHEAGHTVLVGGRRRDELEVLAKELDTDA
TH_1175|M.thermoresistible__bu --MDVLVTGGDTDLGRTIAAGFVDAGHNVVIAGAHRDEIELAAKELDVES
MAB_2432c|M.abscessus_ATCC_199 --MDVLVTGAVNEVGRAVAAEFRNAGHRVVITGPNADELEIAAKELEVDA
:**:** .::**::* * : ** * : * . ::*: ****: ::
Mb1887c|M.bovis_AF2122/97 VVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAW
Rv1856c|M.tuberculosis_H37Rv VVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAW
MLBr_02059|M.leprae_Br4923 IVCNTTDPASLDEARGLFPRHLNTIVNVPTLGFDTGDPRTFSLSDTANAW
MMAR_2730|M.marinum_M IACDITNPASLAEVRGLFPHHLDTIVNVPAPTWDAGDPRTYSLADTATAW
MUL_3023|M.ulcerans_Agy99 IACDITNPASLAEVRGLFPHHLDTIVNVPAPTWDAGDPRTYSLADTATAW
MAV_2864|M.avium_104 IVCDTTDPAALEQARPLFPHHLDTVVHVPAPSWEAGDPRTYSIADTASAW
MSMEG_3619|M.smegmatis_MC2_155 IVFDNTDAASLEAVRGQFPHHLDTLVNVPAPRWEAKDPRTYTLADLASAW
Mvan_3076|M.vanbaalenii_PYR-1 LVFDNTDPASVAALHGQVPAHLDTIINMPAPTWTVGDPRTYTLADHAAEW
Mflv_3346|M.gilvum_PYR-GCK YVFDNTDPASVGDLHGQVPAHLDAIINVPAPTWVGGDPRAYTLTDHAAQW
TH_1175|M.thermoresistible__bu LVFDNTDPDSVEQTRARLPHHLDSVVNVPVLP-ELGDPRTYSTADLAHAW
MAB_2432c|M.abscessus_ATCC_199 IVCDNADPDSLEDNVELFPQHLDAIVNIPNPVWSEPGPHLGTLTDTGEAW
. : ::. :: .* **::::::* .*: : :* . *
Mb1887c|M.bovis_AF2122/97 RNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAGG-AESAIKAAL
Rv1856c|M.tuberculosis_H37Rv RNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAGG-AESAIKAAL
MLBr_02059|M.leprae_Br4923 HNELDATVLSAVLTVQSVGDHLRSGGSIIGVLAENPPAGS-VDAAIKAAL
MMAR_2730|M.marinum_M RNALDTTVLSAVLTVQCVGDHLRSGGSIISVVAENPPAGS-VDAAIKGAL
MUL_3023|M.ulcerans_Agy99 RNALDTTALSAVLTVQCVGDHLRSGGSIISVVAENPPAGS-VDAAIKGAL
MAV_2864|M.avium_104 RNALDATVLSAVLTVQTVGDHLRSGGSIISVVPENPPAGS-AQAAVKAAL
MSMEG_3619|M.smegmatis_MC2_155 RNNLDATVVSAALTVQIVGDHLRSGGSIVNVLPESAKEGS-VEAAIKAAL
Mvan_3076|M.vanbaalenii_PYR-1 RGLFDAGLVASVLTVQVLGDHMRSGGSIINVIPDFVRDGS-AAAAVKAAV
Mflv_3346|M.gilvum_PYR-GCK RGLFDANLLASVLTVQVLGDHMRSGGSIITVIPDLPEEGG-AASAVKAAV
TH_1175|M.thermoresistible__bu RATFDAVMLSTVLTVQIAGDHLRSGGSIINVIPDAPRDGS-AGAAVKAAL
MAB_2432c|M.abscessus_ATCC_199 LSRYESSVLTAVLTVQAIGDHLRSGAAIINLCTLGTRDRSGATTAAKAAL
:: :: .**** ***:***.:*: : . . . :* *.*:
Mb1887c|M.bovis_AF2122/97 SNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSHTPAP---VAAEIAR
Rv1856c|M.tuberculosis_H37Rv SNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSRTPAP---VAAEIAR
MLBr_02059|M.leprae_Br4923 SSWVAGQAGVFGTRGITVNAIACGRSVQAGYEGLSRMPPH---VATEITR
MMAR_2730|M.marinum_M SNWVAGQAEIYGTRGITVNAVACGRSVQAGYEGLSRTPAP---VAAEIAR
MUL_3023|M.ulcerans_Agy99 SNWVAGQAEIYGTRGITVNAVACGRSVQAGYEGLSRTPAP---VAAEIAR
MAV_2864|M.avium_104 SNWTTGQASVFGTRGITVNAVASGRGAQPGYDGLSRSPAP---VAAEVAR
MSMEG_3619|M.smegmatis_MC2_155 SDWTAGQADFFGTRGITINAVAAGRSAEQAYDGLTRTPPS---VADEFTR
Mvan_3076|M.vanbaalenii_PYR-1 SDWTAGQADQFGVRGITVNAVAVGRGVEPGYDGLGSTPPS---VAAEISR
Mflv_3346|M.gilvum_PYR-GCK SDWTAGLANHFGIRGITINAVAVGRGVEPGYDGVGATPPP---ASTEISR
TH_1175|M.thermoresistible__bu SDWTAGQAAVFGTRGITVNAVAAGDSAEPGYDGLTRTPPT---LGAELAR
MAB_2432c|M.abscessus_ATCC_199 SAWTAEQAERMGTRGITINTIAPGQSAEANYDGLDSTEDAHELVAGEIAR
* * : * * ****:*::* * ..: *:*: . *.:*
Mb1887c|M.bovis_AF2122/97 LALFLTTPAARHITGQTLHVSHGALAHFG
Rv1856c|M.tuberculosis_H37Rv LALFLTTPAARHITGQTLHVSHGALAHFG
MLBr_02059|M.leprae_Br4923 LALFLTTPASRHITGQTLHVSHGALTHF-
MMAR_2730|M.marinum_M LALFLTTPAARHITGQTLHVSHGALAHFA
MUL_3023|M.ulcerans_Agy99 LALFLTTPAARHITGQTLHVSHGALAHFA
MAV_2864|M.avium_104 LALFLTSPAARHITGQTLHVSHGALAHFA
MSMEG_3619|M.smegmatis_MC2_155 LALFLSTPAARHITGQTLHVSRGALATV-
Mvan_3076|M.vanbaalenii_PYR-1 LSLFLTTPAARHITGQTLHVTHGALANFG
Mflv_3346|M.gilvum_PYR-GCK LSLFLTTPAARHITGQTLHVSHGALANFA
TH_1175|M.thermoresistible__bu MAVFIATPAARHITGQTLHVSRGVPARVG
MAB_2432c|M.abscessus_ATCC_199 LALFLASPQARHITGQTLHVSRGVPAGVS
:::*:::* :**********::*. : .