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M. leprae Br4923 MLBr_02059 (-)

annotation: short chain dehydrogenase
coordinates: 2446481 - 2447155
length: 224

MAVDVLVTGGNTDLGRTIAEGFRNDGHKVTLVGPRRADLEVVAKELDVDTIVCNTTDPASLDEARGLFPR
HLNTIVNVPTLGFDTGDPRTFSLSDTANAWHNELDATVLSAVLTVQSVGDHLRSGGSIIGVLAENPPAGS
VDAAIKAALSSWVAGQAGVFGTRGITVNAIACGRSVQAGYEGLSRMPPHVATEITRLALFLTTPASRHIT
GQTLHVSHGALTHF
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02059--100% (224)short chain dehydrogenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1887c-1e-10379.91% (224) short chain dehydrogenase
M. gilvum PYR-GCKMflv_3346-1e-7058.11% (222) short chain dehydrogenase
M. tuberculosis H37RvRv1856c-1e-10480.36% (224) short chain dehydrogenase
M. abscessus ATCC 19977MAB_2432c-3e-5752.70% (222) short chain dehydrogenase
M. marinum MMMAR_2730-1e-10280.80% (224) oxidoreductase
M. avium 104MAV_2864-8e-9472.07% (222) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_3619-4e-8166.51% (218) short chain dehydrogenase
M. thermoresistible (build 8)TH_1175-2e-7259.45% (217) POSSIBLE OXIDOREDUCTASE
M. ulcerans Agy99MUL_3023-1e-10180.36% (224) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_3076-1e-7259.91% (222) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mb1887c|M.bovis_AF2122/97           MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDA
Rv1856c|M.tuberculosis_H37Rv        MAVEVLVTGGDTDLGRTMAEGFRNDGHKVTLVGARRGDLEVAAKELDVDA
MLBr_02059|M.leprae_Br4923          MAVDVLVTGGNTDLGRTIAEGFRNDGHKVTLVGPRRADLEVVAKELDVDT
MMAR_2730|M.marinum_M               MAVEVLVTGGDTDLGRTVAEGFRDDGHKVTLVGARRDDLEVVAKELDADA
MUL_3023|M.ulcerans_Agy99           MAVEVLVTGGDTDLGRTVAEGFRDDGHKVTLVGARRDDLEVVAKELDADA
MAV_2864|M.avium_104                --MEVLVTGGDTELGRAVAEGFRDDGHKVTLVGARKSDLEIAAKELEAEA
MSMEG_3619|M.smegmatis_MC2_155      -MAEVLVTGGDTELGRAIAQGFRDAGHNVVIAGARRDDLEVAAKELDIES
Mflv_3346|M.gilvum_PYR-GCK          --MDVLVTGCDTDLGRTIAEGFHEAGHTVLVGGRRRDELEVLAKELDTDA
Mvan_3076|M.vanbaalenii_PYR-1       --MDVLITGCDTDLGRTIAESFSEAGHKVLVGGRRRDELEVLAKELDVDA
TH_1175|M.thermoresistible__bu      --MDVLVTGGDTDLGRTIAAGFVDAGHNVVIAGAHRDEIELAAKELDVES
MAB_2432c|M.abscessus_ATCC_199      --MDVLVTGAVNEVGRAVAAEFRNAGHRVVITGPNADELEIAAKELEVDA
                                       :**:**  .::**::*  * : ** * : * .  ::*: ****: ::

Mb1887c|M.bovis_AF2122/97           VVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAW
Rv1856c|M.tuberculosis_H37Rv        VVCDTTDPTSLTEARGLFPRHLDTIVNVPAPSWDAGDPRAYSVSDTANAW
MLBr_02059|M.leprae_Br4923          IVCNTTDPASLDEARGLFPRHLNTIVNVPTLGFDTGDPRTFSLSDTANAW
MMAR_2730|M.marinum_M               IACDITNPASLAEVRGLFPHHLDTIVNVPAPTWDAGDPRTYSLADTATAW
MUL_3023|M.ulcerans_Agy99           IACDITNPASLAEVRGLFPHHLDTIVNVPAPTWDAGDPRTYSLADTATAW
MAV_2864|M.avium_104                IVCDTTDPAALEQARPLFPHHLDTVVHVPAPSWEAGDPRTYSIADTASAW
MSMEG_3619|M.smegmatis_MC2_155      IVFDNTDAASLEAVRGQFPHHLDTLVNVPAPRWEAKDPRTYTLADLASAW
Mflv_3346|M.gilvum_PYR-GCK          YVFDNTDPASVGDLHGQVPAHLDAIINVPAPTWVGGDPRAYTLTDHAAQW
Mvan_3076|M.vanbaalenii_PYR-1       LVFDNTDPASVAALHGQVPAHLDTIINMPAPTWTVGDPRTYTLADHAAEW
TH_1175|M.thermoresistible__bu      LVFDNTDPDSVEQTRARLPHHLDSVVNVPVLP-ELGDPRTYSTADLAHAW
MAB_2432c|M.abscessus_ATCC_199      IVCDNADPDSLEDNVELFPQHLDAIVNIPNPVWSEPGPHLGTLTDTGEAW
                                     . : ::. ::      .* **::::::*       .*:  : :* .  *

Mb1887c|M.bovis_AF2122/97           RNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAGG-AESAIKAAL
Rv1856c|M.tuberculosis_H37Rv        RNALDATVLSVVLTVQSVGDHLRSGGSIVSVVAENPPAGG-AESAIKAAL
MLBr_02059|M.leprae_Br4923          HNELDATVLSAVLTVQSVGDHLRSGGSIIGVLAENPPAGS-VDAAIKAAL
MMAR_2730|M.marinum_M               RNALDTTVLSAVLTVQCVGDHLRSGGSIISVVAENPPAGS-VDAAIKGAL
MUL_3023|M.ulcerans_Agy99           RNALDTTALSAVLTVQCVGDHLRSGGSIISVVAENPPAGS-VDAAIKGAL
MAV_2864|M.avium_104                RNALDATVLSAVLTVQTVGDHLRSGGSIISVVPENPPAGS-AQAAVKAAL
MSMEG_3619|M.smegmatis_MC2_155      RNNLDATVVSAALTVQIVGDHLRSGGSIVNVLPESAKEGS-VEAAIKAAL
Mflv_3346|M.gilvum_PYR-GCK          RGLFDANLLASVLTVQVLGDHMRSGGSIITVIPDLPEEGG-AASAVKAAV
Mvan_3076|M.vanbaalenii_PYR-1       RGLFDAGLVASVLTVQVLGDHMRSGGSIINVIPDFVRDGS-AAAAVKAAV
TH_1175|M.thermoresistible__bu      RATFDAVMLSTVLTVQIAGDHLRSGGSIINVIPDAPRDGS-AGAAVKAAL
MAB_2432c|M.abscessus_ATCC_199      LSRYESSVLTAVLTVQAIGDHLRSGAAIINLCTLGTRDRSGATTAAKAAL
                                        ::  :: .****  ***:***.:*: : .      . . :* *.*:

Mb1887c|M.bovis_AF2122/97           SNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSHTPAP---VAAEIAR
Rv1856c|M.tuberculosis_H37Rv        SNWIAGQAAVFGTRGITINTVACGRSVQTGYEGLSRTPAP---VAAEIAR
MLBr_02059|M.leprae_Br4923          SSWVAGQAGVFGTRGITVNAIACGRSVQAGYEGLSRMPPH---VATEITR
MMAR_2730|M.marinum_M               SNWVAGQAEIYGTRGITVNAVACGRSVQAGYEGLSRTPAP---VAAEIAR
MUL_3023|M.ulcerans_Agy99           SNWVAGQAEIYGTRGITVNAVACGRSVQAGYEGLSRTPAP---VAAEIAR
MAV_2864|M.avium_104                SNWTTGQASVFGTRGITVNAVASGRGAQPGYDGLSRSPAP---VAAEVAR
MSMEG_3619|M.smegmatis_MC2_155      SDWTAGQADFFGTRGITINAVAAGRSAEQAYDGLTRTPPS---VADEFTR
Mflv_3346|M.gilvum_PYR-GCK          SDWTAGLANHFGIRGITINAVAVGRGVEPGYDGVGATPPP---ASTEISR
Mvan_3076|M.vanbaalenii_PYR-1       SDWTAGQADQFGVRGITVNAVAVGRGVEPGYDGLGSTPPS---VAAEISR
TH_1175|M.thermoresistible__bu      SDWTAGQAAVFGTRGITVNAVAAGDSAEPGYDGLTRTPPT---LGAELAR
MAB_2432c|M.abscessus_ATCC_199      SAWTAEQAERMGTRGITINTIAPGQSAEANYDGLDSTEDAHELVAGEIAR
                                    * * :  *   * ****:*::* * ..:  *:*:          . *.:*

Mb1887c|M.bovis_AF2122/97           LALFLTTPAARHITGQTLHVSHGALAHFG
Rv1856c|M.tuberculosis_H37Rv        LALFLTTPAARHITGQTLHVSHGALAHFG
MLBr_02059|M.leprae_Br4923          LALFLTTPASRHITGQTLHVSHGALTHF-
MMAR_2730|M.marinum_M               LALFLTTPAARHITGQTLHVSHGALAHFA
MUL_3023|M.ulcerans_Agy99           LALFLTTPAARHITGQTLHVSHGALAHFA
MAV_2864|M.avium_104                LALFLTSPAARHITGQTLHVSHGALAHFA
MSMEG_3619|M.smegmatis_MC2_155      LALFLSTPAARHITGQTLHVSRGALATV-
Mflv_3346|M.gilvum_PYR-GCK          LSLFLTTPAARHITGQTLHVSHGALANFA
Mvan_3076|M.vanbaalenii_PYR-1       LSLFLTTPAARHITGQTLHVTHGALANFG
TH_1175|M.thermoresistible__bu      MAVFIATPAARHITGQTLHVSRGVPARVG
MAB_2432c|M.abscessus_ATCC_199      LALFLASPQARHITGQTLHVSRGVPAGVS
                                    :::*:::* :**********::*. : .