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VPAGGPAAASSPLAVRMRPASLDEVVGQGHLLKPNSPLRRLIEGSGAASVILYGPPGTGKTTLASMISQA TGRRFEALSALAAGVKEVRAVIDVARQASMRGEQTVLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTE NPSFSVVAPLLSRSLILQLQPLTPEDVTTVIRRAIEDPRGLGGKVAVTDEAVDQLVQLSAGDARRALTAL EVASESGEEVTVEVIEQSLDKAAVRYDRDGDQHYDVVSAFIKSVRGSDVDAALHYLARMLVAGEDPRFVA RRLMILASEDIGMADPTALPTAVAAAQTVQLIGMPEAQLTLAHATVHLATAPKSNAVTTALGAAMADIRA GKAGLVPAHLRDGHYSGAQKMGNAVGYKYAHDSPDGVVPQQYPPDDLVGVDYYRPTNHGVEREISTRVDK LRAIIRRRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2635 | - | - | 100% (429) | recombination factor protein RarA |
| M. vanbaalenii PYR-1 | Mvan_2575 | ruvB | 3e-12 | 25.85% (352) | Holliday junction DNA helicase B |
| M. vanbaalenii PYR-1 | Mvan_5534 | - | 4e-08 | 22.48% (298) | DNA polymerase III subunits gamma and tau |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2589c | - | 0.0 | 82.67% (427) | recombination factor protein RarA |
| M. gilvum PYR-GCK | Mflv_3766 | - | 0.0 | 91.20% (432) | recombination factor protein RarA |
| M. tuberculosis H37Rv | Rv2559c | - | 0.0 | 82.44% (427) | recombination factor protein RarA |
| M. leprae Br4923 | MLBr_00510 | - | 0.0 | 79.57% (421) | recombination factor protein RarA |
| M. abscessus ATCC 19977 | MAB_2853c | - | 0.0 | 79.32% (440) | hypothetical protein MAB_2853c |
| M. marinum M | MMAR_2167 | - | 0.0 | 81.63% (430) | hypothetical protein MMAR_2167 |
| M. avium 104 | MAV_3435 | - | 0.0 | 83.14% (421) | recombination factor protein RarA |
| M. smegmatis MC2 155 | MSMEG_3021 | - | 0.0 | 87.88% (429) | recombination factor protein RarA |
| M. thermoresistible (build 8) | TH_0117 | - | 0.0 | 87.06% (425) | CONSERVED HYPOTHETICAL ALANINE LEUCINE VALINE RICH PROTEIN |
| M. ulcerans Agy99 | MUL_1751 | - | 0.0 | 82.39% (426) | recombination factor protein RarA |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2635|M.vanbaalenii_PYR-1 --------------------------------------------MPAGGP
Mflv_3766|M.gilvum_PYR-GCK --------------------------MSDSLFDVPGE-----PAPPAAGP
MSMEG_3021|M.smegmatis_MC2_155 --------------------------MSDSLFDVPGGGAESGDAIAATGA
MLBr_00510|M.leprae_Br4923 MGTRWVPESSGFTVTDLSVLRGISNVVSDSLFDLPGAP----QPTDYGLG
MAV_3435|M.avium_104 --------------------------MSDGLFDLPGAP----PPGDHGLG
Mb2589c|M.bovis_AF2122/97 ----------------------MPEAVSDGLFDVPGVP----MTSGHDLG
Rv2559c|M.tuberculosis_H37Rv ----------------------MPEAVSDGLFDVPGVP----MTSGHDLG
MMAR_2167|M.marinum_M ----------------------MSEPVSDGLFDLPGAP----QHSDHGLE
MUL_1751|M.ulcerans_Agy99 ----------------------MSEPVSDGLFDLPGAP----QHSDHALE
TH_0117|M.thermoresistible__bu --------------------------VSDSLFDLPGEP----ASTAEPGA
MAB_2853c|M.abscessus_ATCC_199 --------------------------MSDSLFDVPGGG---FDSSSADPG
Mvan_2635|M.vanbaalenii_PYR-1 AAASSPLAVRMRPASLDEVVGQGHLLKPNSPLRRLIEGSGAASVILYGPP
Mflv_3766|M.gilvum_PYR-GCK VGASVPLAVRMRPANLDEVVGQDHLLKPNSPLRRLIEGSGAASVILYGPP
MSMEG_3021|M.smegmatis_MC2_155 VGPSSPLAVRMRPAGLDEVVGQSHLLQAGSPLRRLVEGSGAASVILYGPP
MLBr_00510|M.leprae_Br4923 GSTGVPLAVRMRPASLDELVGQGHLLAPGSPLRRLVEGSGVVSAILHGPP
MAV_3435|M.avium_104 VPAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASAILYGPP
Mb2589c|M.bovis_AF2122/97 ASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPP
Rv2559c|M.tuberculosis_H37Rv ASAGAPLAVRMRPASLDEVVGQDHLLAPGSPLRRLVEGSGVASVILYGPP
MMAR_2167|M.marinum_M VSAGAPLAVRMRPESLDEVVGQGHLLAPGAPLRRLVEGSGVASVILYGPP
MUL_1751|M.ulcerans_Agy99 VSAGAPLAVRMRPESLDEVVGQGHLLAPGAPLRRLVEGSGVASVILYGPP
TH_0117|M.thermoresistible__bu PTTPAPLAVRMRPANLDEVVGQDHLLQPGAPLRRLVEGSGAASVILYGPP
MAB_2853c|M.abscessus_ATCC_199 VPPNAPLAVRMRPATLDEVVGQGHLLKQGSPLRRLVDGSGAASVILYGPP
. ******** ***:***.*** .:*****::***..*.**:***
Mvan_2635|M.vanbaalenii_PYR-1 GTGKTTLASMISQATGRRFEALSALAAGVKEVRAVIDVARQASM-RGEQT
Mflv_3766|M.gilvum_PYR-GCK GTGKTTLASMISQATGRRFEALSALAAGVKEVRAVIDVARQAAV-RGEQT
MSMEG_3021|M.smegmatis_MC2_155 GTGKTTLASLISQATGRRFEALSALTAGVKEVRAVIDTARRAAV-HGQQT
MLBr_00510|M.leprae_Br4923 GCGKTTLAALISQATGHRFEALSALSAGVKDVRAVLKIARSALL-SGKRT
MAV_3435|M.avium_104 GSGKTTLAALISQATGRRFEALSALSAGVKDVRAVIESARTALL-RGEQT
Mb2589c|M.bovis_AF2122/97 GSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALL-HGEQT
Rv2559c|M.tuberculosis_H37Rv GSGKTTLAALISQATGRRFEALSALSAGVKEVRAVIENSRKALL-HGEQT
MMAR_2167|M.marinum_M GSGKTTLAALISHATGRRFEALSALSAGVKDVRAVIETARQVLR-RGEQT
MUL_1751|M.ulcerans_Agy99 GSGKTTLAALISHATGRRFEALSALSAGVKDVRAVIETARQVLR-RGEQT
TH_0117|M.thermoresistible__bu GTGKTTLASLISQATGRRFEALSALSAGVKEVRAVIDTARRAAM-RGEQT
MAB_2853c|M.abscessus_ATCC_199 GTGKTTLASLISGATGRRFEALSALSAGVKEVRAVIENSRTALAYHGQQT
* ******::** ***:********:****:****:. :* . *::*
Mvan_2635|M.vanbaalenii_PYR-1 VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
Mflv_3766|M.gilvum_PYR-GCK VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
MSMEG_3021|M.smegmatis_MC2_155 VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
MLBr_00510|M.leprae_Br4923 VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
MAV_3435|M.avium_104 VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
Mb2589c|M.bovis_AF2122/97 VLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSL
Rv2559c|M.tuberculosis_H37Rv VLFIDEVHRFSKTQQDALLSAVEHRVVLLVAATTENPSFSVVAPLLSRSL
MMAR_2167|M.marinum_M VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
MUL_1751|M.ulcerans_Agy99 VLFIDEVHRFSKTQQDALLSAVENRVVLLVAATTENPSFSVVAPLLSRSL
TH_0117|M.thermoresistible__bu VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
MAB_2853c|M.abscessus_ATCC_199 VLFIDEVHRFSKTQQDALLAAVENRVVLLVAATTENPSFSVVAPLLSRSL
*******************:***:**************************
Mvan_2635|M.vanbaalenii_PYR-1 ILQLQPLTPEDVTTVIRRAIEDPRGLGGKVAVTDEAVDQLVQLSAGDARR
Mflv_3766|M.gilvum_PYR-GCK ILQLQPLTPADVTTVIRRAITDERGLGGRVTVSDDAIEQLVLLSAGDARR
MSMEG_3021|M.smegmatis_MC2_155 ILQLQPLTPADIEAVLRRAITDERGLGGRVEVTDEAVDLIVQLSAGDARR
MLBr_00510|M.leprae_Br4923 ILQLRPLNADDIRAVVQRAVDDPRGLGGQIAVAPEAVDLLVRLAAGDARR
MAV_3435|M.avium_104 ILQLRPLSADDIRTVVRRAIDDPRGLGGRVPVAPEAVDLLVRLAAGDARR
Mb2589c|M.bovis_AF2122/97 ILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARR
Rv2559c|M.tuberculosis_H37Rv ILQLRPLTAEDTRAVVQRAIDDPRGLGRAVAVAPEAVDLLVQLAAGDARR
MMAR_2167|M.marinum_M ILQLHPLGADDIRAVVQRAAQDPRGLGGRVAIAPDATDLLVQLSAGDARR
MUL_1751|M.ulcerans_Agy99 ILQLHPLGAEDIRAVVQRAAQDPRGLGGRVAIAPDATDLLVQLSAGDARR
TH_0117|M.thermoresistible__bu ILQLQPLDTDAIRTVVRRAIDDPRGLGGKVEVSDDAVELLVQLSAGDARR
MAB_2853c|M.abscessus_ATCC_199 ILQLQPLADNDIREVLTRAIADERGLGGAVAVDPEALSLLVQLAAGDARR
****:** *: ** * **** : : :* . :* *:******
Mvan_2635|M.vanbaalenii_PYR-1 ALTALEVASE----SGEEVTVEVIEQSLDKAAVRYDRDGDQHYDVVSAFI
Mflv_3766|M.gilvum_PYR-GCK ALTALEVATETVSESGETVTVEVIEQSLDKAALRYDRDGDQHYDVVSAFI
MSMEG_3021|M.smegmatis_MC2_155 ALTALEVAAE----PGERVTVETIEQSLDKAAVRYDRDGDQHYDVVSAFI
MLBr_00510|M.leprae_Br4923 VLTALEVAAEAVQTG-DELTVATIEQSLDNAAVRYDRDGDQHYDIVSAFI
MAV_3435|M.avium_104 ALTALEVAAEAGES----VTVQTVEQSLDEAAVRYDRDGDQHYDVISAFI
Mb2589c|M.bovis_AF2122/97 ALTALEVAAEAAQAAGELVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFI
Rv2559c|M.tuberculosis_H37Rv ALTALEVAAEAAQAAGELVSVQTIERSVDKAAVRYDRDGDQHYDVVSAFI
MMAR_2167|M.marinum_M ALTALEVAAEAAQAAGSQVSVEIIEQSLDKAAVRYDRDGDQHYDVVSAFI
MUL_1751|M.ulcerans_Agy99 ALTALEVAAEAAQAAGSQVSVEIIEQSLDKAAVRYDRDGDQHYDVVSAFI
TH_0117|M.thermoresistible__bu ALTALEVAAEAGER----VTVGTIEQSLDQAAVRYDRDGDQHYDVVSAFI
MAB_2853c|M.abscessus_ATCC_199 ALTALEVAFETAGGAGSVISVEVVEQSVDRAAVRYDRDGDQHYDVVSAFI
.******* * ::* :*:*:*.**:***********::****
Mvan_2635|M.vanbaalenii_PYR-1 KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGMADPTALPT
Mflv_3766|M.gilvum_PYR-GCK KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGMADPTALQI
MSMEG_3021|M.smegmatis_MC2_155 KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGMADPTALQT
MLBr_00510|M.leprae_Br4923 KSVRGSDVDAALHYLARMLIAGEDPRFIARRLLILASEDIGLADSTALPL
MAV_3435|M.avium_104 KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADSAALQV
Mb2589c|M.bovis_AF2122/97 KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADPSALQV
Rv2559c|M.tuberculosis_H37Rv KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMAGPSALQV
MMAR_2167|M.marinum_M KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGLADPTALPT
MUL_1751|M.ulcerans_Agy99 KSVRGSDVDAALHYLARMLVAGEDPRFVARRLMILASEDIGLADPTALPT
TH_0117|M.thermoresistible__bu KSVRGSDVDAALHYLARMLVAGEDPRFIARRLMILASEDIGMADPTALPL
MAB_2853c|M.abscessus_ATCC_199 KSIRGSDVDAALHYLARMLTAGEDPRFVARRLMILASEDVGMADPTALPL
**:**************** *******:****:******:*:*..:**
Mvan_2635|M.vanbaalenii_PYR-1 AVAAAQTVQLIGMPEAQLTLAHATVHLATAPKSNAVTTALGAAMADIRAG
Mflv_3766|M.gilvum_PYR-GCK AVAAAQTVQLIGMPEAQLTLAQATVHLATAPKSNAVTTALGAAMADIRAG
MSMEG_3021|M.smegmatis_MC2_155 AVAAAQTVQLIGMPEAQLTLAHATVHLATAPKSNAVTTALGAAMNDIRAG
MLBr_00510|M.leprae_Br4923 AVAAAQTVQLIGMPEAQLALAHATIHLATAPKSNAVMTALGSAIDDIKAG
MAV_3435|M.avium_104 AVAAAQTVALIGMPEAQLTLAHCTVYLATAPKSNAVTTALGAAMSDIKAG
Mb2589c|M.bovis_AF2122/97 AVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAG
Rv2559c|M.tuberculosis_H37Rv AVAAAQTVALIGMPEAQLTLAHATIHLATAPKSNAVTTALAAAMNDIKAG
MMAR_2167|M.marinum_M AVAAAQTVALIGLPEAQLTLAHATIHLATAPKSNAVTTALAAAMADIKAG
MUL_1751|M.ulcerans_Agy99 AVAAAQTVALIGLPEAQLTLAHATIHLATAPKSNAVTTALAAAMADIKAG
TH_0117|M.thermoresistible__bu AVAAAQTVQLIGMPEAQLTLAHATVHLATAPKSNAVTTALGAAMADIRAG
MAB_2853c|M.abscessus_ATCC_199 AVAAAQTVQLIGMPEAQLTLTHATIHLATAPKSGAVPAALGAAMGDIREG
******** ***:*****:*::.*::*******.** :**.:*: **: *
Mvan_2635|M.vanbaalenii_PYR-1 KAGLVPAHLRDGHYSGAQKMGNAVGYKYAHDSPDGVVPQQYPPDDLVGVD
Mflv_3766|M.gilvum_PYR-GCK KAGQVPAHLRDGHYSGAQKLGNAVGYKYAHDHPGGVASQQYPPDELVGTD
MSMEG_3021|M.smegmatis_MC2_155 KAGLVPPHLRDGHYSGAAKLGHAVGYRYSHDHPDGVVAQQYPPDELVGVD
MLBr_00510|M.leprae_Br4923 KAGLVPAHLRDGHYSGAAALGNAKGYKYSHDDPDGVVAQQYPPYELVEVD
MAV_3435|M.avium_104 KAGLVPAHLRDGHYSGAAALGHAQGYQYSHDHPDGVVAQQYPPDELVGVD
Mb2589c|M.bovis_AF2122/97 KAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELVDVD
Rv2559c|M.tuberculosis_H37Rv KAGLVPAHLRDGHYSGAAALGNAQGYKYSHDDPDGVVAQQYPPDELVDVD
MMAR_2167|M.marinum_M KAGLVPPHLRDGHYSGAAALGHAQGYKYSHDDPDGVVAQQYPPDELVGTN
MUL_1751|M.ulcerans_Agy99 KAGLVPPHLRDGHYSGAAALGHAQGYKYSHDDPDGVVAQQYPPDELVGTN
TH_0117|M.thermoresistible__bu KAGLVPAHLRDGHYSGAARLGHAQGYKYSHDHPDGVVAQQYPPDTLVGVD
MAB_2853c|M.abscessus_ATCC_199 KAGLVPPHLRDGHYSGAAKLGNAVGYVYPHNDRDGVVAQQYPPDELVGAD
*** **.********** :*:* ** *.*: .**..***** ** .:
Mvan_2635|M.vanbaalenii_PYR-1 YYRPTNHGVEREISTRVDKLRAIIRRRR---
Mflv_3766|M.gilvum_PYR-GCK YYRPTNHGVEREISARVEKLRAIIRRSR---
MSMEG_3021|M.smegmatis_MC2_155 YYQPTGRGYEREISTRLDKLRAIIRRRR---
MLBr_00510|M.leprae_Br4923 YYRPTGRGGERELVGRLDRLRAIIRGRRG--
MAV_3435|M.avium_104 YYRPTGRGAEREIAGRLDRLRAIIRNKRGRS
Mb2589c|M.bovis_AF2122/97 YYRPTGRGGEREIAGRLDRLRAIIRKKRG--
Rv2559c|M.tuberculosis_H37Rv YYRPTGRGGEREIAGRLDRLRAIIRKKRG--
MMAR_2167|M.marinum_M YYRPTGRGGEREIGGRLERLRAIIRRKRA--
MUL_1751|M.ulcerans_Agy99 YYRPTGRGGEREIGGRLERLRAIIRRKRA--
TH_0117|M.thermoresistible__bu YYRPTGRGAEREIAGRVDRLRAIIRGLRGRS
MAB_2853c|M.abscessus_ATCC_199 YYQPTDHGNEREIGSRLEKLRAIVRRGLKR-
**:**.:* ***: *:::****:*