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TRSSVVTVLRVTLLWAAGISVLFPIVWIALASLKTPEQLNDPFLIAFTPNFASWQNVLSSGILGAAGRSA LVALVTVGISVVVGSMGAYAIARYRAGGTLTRFGMLAAQVLPPAVLVFPFLTMAYALRLTDTLIPVIFSH LSFVLPVVTWFLIGFFEAVPRSLEEQAQVDGLTRFTAFRLVVLPQVYPGIGAAAIFGFTLSWNDLFYGLI LAPGKAAILPVAIAGFNTFRGVQIGSMSAAILIAVVPVVIASFFIQRKLVQGISGGAVKF*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2622 | - | - | 100% (271) | binding-protein-dependent transport systems inner membrane component |
| M. vanbaalenii PYR-1 | Mvan_2542 | - | 2e-31 | 31.02% (274) | binding-protein-dependent transport systems inner membrane |
| M. vanbaalenii PYR-1 | Mvan_3390 | - | 9e-10 | 26.05% (261) | binding-protein-dependent transport systems inner membrane |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1269 | sugB | 2e-36 | 35.18% (253) | sugar-transport integral membrane protein ABC transporter |
| M. gilvum PYR-GCK | Mflv_3777 | - | 1e-141 | 94.10% (271) | binding-protein-dependent transport systems inner membrane |
| M. tuberculosis H37Rv | Rv1237 | sugB | 2e-36 | 35.18% (253) | sugar-transport integral membrane protein ABC transporter |
| M. leprae Br4923 | MLBr_01088 | - | 9e-35 | 34.39% (253) | putative ABC-transport protein, inner membrane component |
| M. abscessus ATCC 19977 | MAB_1374 | - | 5e-31 | 31.62% (253) | sugar ABC transporter, permease protein SugB |
| M. marinum M | MMAR_4204 | sugB | 5e-35 | 33.98% (256) | sugar-transport integral membrane protein ABC transporter |
| M. avium 104 | MAV_1376 | sugB | 1e-34 | 33.85% (260) | ABC transporter, permease protein SugB |
| M. smegmatis MC2 155 | MSMEG_3109 | - | 1e-118 | 77.12% (271) | binding-protein-dependent transport systems inner membrane |
| M. thermoresistible (build 8) | TH_2867 | - | 2e-35 | 35.94% (256) | PUTATIVE binding-protein-dependent transport systems inner |
| M. ulcerans Agy99 | MUL_4511 | sugB | 2e-29 | 32.51% (243) | sugar-transport integral membrane protein ABC transporter |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4204|M.marinum_M -----------MTTGSGRRTFWVVIDTMVVVYALLPVLWILSLSLKPTST
MUL_4511|M.ulcerans_Agy99 ----------------------------------------MSLSPKPTST
Mb1269|M.bovis_AF2122/97 -------------MGARRATYWAVLDTLVVGYALLPVLWIFSLSLKPTST
Rv1237|M.tuberculosis_H37Rv -------------MGARRATYWAVLDTLVVGYALLPVLWIFSLSLKPTST
MLBr_01088|M.leprae_Br4923 MGIEKVKVTAGVRVGARRATIWVIIDTFVVGYALLPVLWILSLSLKPAST
MAV_1376|M.avium_104 -----------------------MIDTLVVVYALLPVLWIFSLSLKPTST
MAB_1374|M.abscessus_ATCC_1997 ----------MSRPDSSRTAGWLIADVLVLCYALVPVLWVLSLSLKPTSS
TH_2867|M.thermoresistible__bu ---------VNERVTARRATGWIVIDLLVILYALFPVLWILSLSLKSTAT
Mvan_2622|M.vanbaalenii_PYR-1 -----------MTRSSVVTVLRVTLLWAAGISVLFPIVWIALASLKTPEQ
Mflv_3777|M.gilvum_PYR-GCK -----------MNRPSVVTVLRVALLWAAAISVLFPIVWIALASVKTPEQ
MSMEG_3109|M.smegmatis_MC2_155 -----------MSRPRWLETLRITVLTVAFLFVLFPIVWVTLASFKSPAQ
* *..
MMAR_4204|M.marinum_M VKDGRLIPSSVTLDNYRGVFGG---DLFSSALINSIGIGLTTTVIAVLLG
MUL_4511|M.ulcerans_Agy99 VKDGRLIPSSVTLDNYRGVFGG---DLFSSALINSIGIGLTTTVIAVLLG
Mb1269|M.bovis_AF2122/97 VKDGKLIPSTVTFDNYRGIFRG---DLFSSALINSIGIGLITTVIAVVLG
Rv1237|M.tuberculosis_H37Rv VKDGKLIPSTVTFDNYRGIFRG---DLFSSALINSIGIGLITTVIAVVLG
MLBr_01088|M.leprae_Br4923 VKDGKLIPSLVTFDNYRGIFRS---DLFSSALINSIGIGLTTTVIAVMFG
MAV_1376|M.avium_104 VKDGKLIPSAISLENYRGIFRG---DFFSSALINSVGIGLITTAVAVLLG
MAB_1374|M.abscessus_ATCC_1997 VKDGKFFPWPITLDNYRGIFSG---NVFTSALVNSIGIGLIATVIAVSVG
TH_2867|M.thermoresistible__bu VKDGKLIPDEITFDNYKAIFRGGGSGVFTSALINSIGIGLITTVIAVVVG
Mvan_2622|M.vanbaalenii_PYR-1 LNDPFLIAFTPNFASWQNVLSSG----ILGAAGRSALVALVTVGISVVVG
Mflv_3777|M.gilvum_PYR-GCK LNDPFLLTFTPDFSGWRNVLESG----ILGAAGRSALVALVTVGISVVVG
MSMEG_3109|M.smegmatis_MC2_155 MSEPFLFVFRPTLDNWQAVLDSG----IFAAAGRSALVGVVTVSISLIVG
:.: :: : .:: :: . : .* .* :.: :. ::: .*
MMAR_4204|M.marinum_M AMAAYAVARLDFPGKRLLVGVALLITMFPAISLVTPLFNIERRIGLFDTW
MUL_4511|M.ulcerans_Agy99 AMAACAVARLDFPGKRLLVGVTLLITMFPAISLVTPLFNIERRIGLFDTW
Mb1269|M.bovis_AF2122/97 AMAAYAVARLEFPGKRLLIGAALLITMFPSISLVTPLFNIERAIGLFDTW
Rv1237|M.tuberculosis_H37Rv AMAAYAVARLEFPGKRLLIGAALLITMFPSISLVTPLFNIERAIGLFDTW
MLBr_01088|M.leprae_Br4923 AMAAYAIARLAFPGKRLLVGTTLLVTMFPAISLVTPLFNIERRVGLFDTW
MAV_1376|M.avium_104 AMAAYAVARLDFPGKRLLIGATLLITMFPAISLVTPLFNIERFLGLFDTW
MAB_1374|M.abscessus_ATCC_1997 TMAAYAVARLDFPGKKALIGAALLIAMFPQISLVTPIFNIERSVGLFDTW
TH_2867|M.thermoresistible__bu GMAAYAVARLNFPGKRLLIGVALLIAMFPQISLVTPLFNIERQLGLFDTW
Mvan_2622|M.vanbaalenii_PYR-1 SMGAYAIARYRAGGTLTRFG-MLAAQVLPPAVLVFPFLTMAYALRLTDTL
Mflv_3777|M.gilvum_PYR-GCK SMGAYAIARYRAGGTLTRFG-MLAAQVLPPAVLVFPFLTMAYALRLTDTL
MSMEG_3109|M.smegmatis_MC2_155 SMGAYVIAKYRAGGSLTRFG-MLAAQVVPPAVMVFPFLTMAHALRLTDTL
*.* .:*: *. .* * :.* :* *::.: : * **
MMAR_4204|M.marinum_M PGLILPYITFALPLAIYTLSAFFREIPWDLEKAAQMDGATPYQAFRKVIV
MUL_4511|M.ulcerans_Agy99 PELILPYITFALPLAIYTLSAFFREIPWDLEKAAQMDGATPYQAFRKVIV
Mb1269|M.bovis_AF2122/97 PGLILPYITFALPLAIYTLSAFFREIPWDLEKAAKMDGATPGQAFRKVIV
Rv1237|M.tuberculosis_H37Rv PGLILPYITFALPLAIYTLSAFFREIPWDLEKAAKMDGATPGQAFRKVIV
MLBr_01088|M.leprae_Br4923 AGLILPYITFALPLAIYTLSAFFAEIPWDLEKAAKMDGATSGQAFRKVIV
MAV_1376|M.avium_104 PGLILPYITFALPLAIYTLSAFFREIPWDLEKAAKIDGATPAQAFRKVIV
MAB_1374|M.abscessus_ATCC_1997 PGLIIPYITFALPLAIYTLSAFFREIPWELEKAAKMDGATPAQAFWKVIA
TH_2867|M.thermoresistible__bu AGLIIPYITFALPLAIYTLSAFFREIPWDLEKAAKMDGATPGQAFRKVIA
Mvan_2622|M.vanbaalenii_PYR-1 IPVIFSHLSFVLPVVTWFLIGFFEAVPRSLEEQAQVDGLTRFTAFRLVVL
Mflv_3777|M.gilvum_PYR-GCK VPVIFAHLSFVLPVVTWFLIGFFEAVPRSLEEQAQVDGLTRFAAFRLVVL
MSMEG_3109|M.smegmatis_MC2_155 APVIFAHLSFVLPLVTWFLIGFFEAVPPSLEEQARVDGFTRWQAFRMVVL
:*:.:::*.**:. : * .** :* .**: *::** * ** *:
MMAR_4204|M.marinum_M PLAAPGLVTAAILVFIFAWNDLLLALSLTATKASITAPVAIANFAGSSQF
MUL_4511|M.ulcerans_Agy99 PLAAPGLVTAAILVFIFAWNDLLLALSLTATKASITAPIAIANFAGSSQF
Mb1269|M.bovis_AF2122/97 PLAAPGLVTAAILVFIFAWNDLLLALSLTATKAAITAPVAIANFTGSSQF
Rv1237|M.tuberculosis_H37Rv PLAAPGLVTAAILVFIFAWNDLLLALSLTATKAAITAPVAIANFTGSSQF
MLBr_01088|M.leprae_Br4923 PLAAPGLVTAAILVFIFAWNDLLLALSLTSTKAAITAPVAITNFTGSSQF
MAV_1376|M.avium_104 PLAAPGVVTAAILVFIFAWNDLLLALTLTATKAAITAPVAIVSFSGSSQF
MAB_1374|M.abscessus_ATCC_1997 PLATPGIVTSAILVFIFAWNDLLLAISLTATDRSITAPVAIANFTGSSQF
TH_2867|M.thermoresistible__bu PLAAPGIVTAAILVFIFAWNDLLLALSLTATERAITAPVAIANFTGSSQF
Mvan_2622|M.vanbaalenii_PYR-1 PQVYPGIGAAAIFGFTLSWNDLFYGLILAPGKAAILP-VAIAGFN--TFR
Mflv_3777|M.gilvum_PYR-GCK PQVLPGIGAAAIFGFTLSWNDLFYGLILAPGKAAILP-VAIAGFN--TFR
MSMEG_3109|M.smegmatis_MC2_155 PQVYPGIGAAGIFGFTLSWNDLFYGLILAPGNAAILP-VAIANFN--TFR
* . **: ::.*: * ::****: .: *:. . :* . :**..* :
MMAR_4204|M.marinum_M EEPTGSIAAGAMVITVPIIVFVLIFQRRIVAGLTSGAVKG
MUL_4511|M.ulcerans_Agy99 EEPTGSIAAGAMVITVPIIVFVLIFQLRIVAGLTSGAVKG
Mb1269|M.bovis_AF2122/97 EEPTGSIAAGAIVITIPIIVFVLIFQRRIVAGLTSGAVKG
Rv1237|M.tuberculosis_H37Rv EEPTGSIAAGAIVITIPIIVFVLIFQRRIVAGLTSGAVKG
MLBr_01088|M.leprae_Br4923 EEPTGSIAAGAIVITAPIIVFVWIFQRRIVAGLTSGAVKG
MAV_1376|M.avium_104 EEPTGSIAAGAVVITVPVILFVLIFQRRIVAGLTSGAVKG
MAB_1374|M.abscessus_ATCC_1997 EEPTGSIAAGAIVITVPIIIFVLIFQRRIVAGLTSGAVKG
TH_2867|M.thermoresistible__bu EEPTGSIAAGAMVITIPIIVFVLIFQRRIVSGLTSGAVKG
Mvan_2622|M.vanbaalenii_PYR-1 GVQIGSMSAAILIAVVPVVIASFFIQRKLVQGISGGAVKF
Mflv_3777|M.gilvum_PYR-GCK GVQIGSMSAAILIAVVPVVIASFFIQRKLVQGISGGAVKF
MSMEG_3109|M.smegmatis_MC2_155 GVQIGTMSAAIMIAIIPVVIASFFIQRRLVQGISGGAVKY
*:::*. :: *::: ::* ::* *::.****