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M. vanbaalenii PYR-1 Mvan_2591 (-)

annotation: hypothetical protein Mvan_2591
coordinates: 2735360 - 2738926
length: 1188

LAAASPRKPRRTSGRHRKPSTRTPWLGVGAVGFGLAAALISGQGVASAAPGDASNSQDSSAGTGDTGDGG
NTVEPGAGTVTSVEDEGSDPDEAPADDTQDDTEDVDDAVDPDGDDPTNDEPANDGAEPVDDESEPEPTEE
PDEDTSPDTPADDQEPAEPSQDPATPAPSTESSAPEPEATESSALPESGSADTAEDSADPVTTESPSSTG
ADASDDGNATAESAVEVDPAQTAVIAMVKELLKAIGITQTGGDGSSPLTSIDELIQGLWLAGRQDQQARA
TQRKAVAALVELVSENSLAQLGTSIGWIPVVGTAVYGVSFLGNLVALGVAVLQGDGAEVADELRDLGRDL
IGMVPVVGAPVAGTLYADDAFPSATARMSTLAAAEPALAAVEPALAAAAAAPVGSQQHFLSVLQRAVSRL
VGWPGTPRNFVDVTNYQTDQTLDLANNQLDGLYANAPVGSQARWLPDMVSIVSLFFIPSVSGATFTDKLN
AMGDFLNRVIPPFTIADGAGTFDIISPYKIMGAAVVGTATVLKDMLNGIYDPVQIEIDVIKATTGATVTA
SDLNDQNALMTKVALAQLGSDPGAFGEPTRAWNVTLPAWTEAQVNPYTLTVYVALVGIYKRFQEMAALTT
FTTWTTYDSWHYTNGLGMYAAGTFHAVDPDGGTIEFRADGTLGKTYTTEGNALVTINTVGGGFTYTPPAI
WDPKFQNAAFFHRSTAEDPEERFDWVTVEAYSADGVPINIRVGIEIIDGTNAAPTYSGITGQNTDALGVV
KGKITGSDSDGDPLRYYLVESSVNGLSGNSAYTKNGAGNGGIVTVSENGDFTYVSNGTAGATQSFQVRIN
DGHHGNTIVTVTVTNTTSITPANVNTSTQNVVTGTVPNSTNKPGAFVSYTLGSSPTKGSVTSFDPTTGAF
TYVRDSGLGHGTTPDDFVTVIATDADGRQVTLRMAVAPTVSNAGPTVVLTTQPTVGTLSGTTQTSTGKLT
YSDPDGDAPVWTTATSSRGATITFAADGTFTYTSNLTVAQRHAVARIGAAGSTYNGVALAAWEDAFTATV
SDGFGGTAQVTVKVPIYAINANPTIGTNSPACGFGTCTVTATTTDPDGDDLSGSLNTSNNGNGDPWYTLA
RGSVTINAGNQHTFSWTGNSNGLGTQQTGIQIYTVYDGHYRVTNGVVDTSYFARAWVQWNNTTRTFGN
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2591--100% (1188)hypothetical protein Mvan_2591
M. vanbaalenii PYR-1Mvan_4736-e-14132.60% (1221) putative outer membrane adhesin like proteiin
M. vanbaalenii PYR-1Mvan_3594-1e-2929.38% (497) YVTN beta-propeller repeat-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3469c-2e-0827.32% (183) hypothetical protein Mb3469c
M. gilvum PYR-GCKMflv_3803-0.066.31% (1208) hypothetical protein Mflv_3803
M. tuberculosis H37RvRv3439c-2e-0827.32% (183) hypothetical protein Rv3439c
M. leprae Br4923MLBr_01022rpoT7e-0623.53% (204) RNA polymerase sigma factor
M. abscessus ATCC 19977MAB_2960-2e-0728.42% (183) hypothetical protein MAB_2960
M. marinum MMMAR_2416lgt3e-0828.24% (170) prolipoprotein diacylglyceryl transferases Lgt
M. avium 104MAV_4382-8e-1030.05% (213) hypothetical protein MAV_4382
M. smegmatis MC2 155MSMEG_3222-1e-1226.79% (224) prolipoprotein diacylglyceryl transferase
M. thermoresistible (build 8)TH_3241-1e-0931.29% (163) PUTATIVE putative FHA domain containing protein
M. ulcerans Agy99MUL_3715rne7e-1030.67% (163) ribonuclease E Rne

CLUSTAL 2.0.9 multiple sequence alignment


Mb3469c|M.bovis_AF2122/97           --------------------------------------------------
Rv3439c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4382|M.avium_104                --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2591|M.vanbaalenii_PYR-1       MAAASPRKPRRTSGRHRKPSTRTPWLGVGAVGFGLAAALISGQGVASAAP
Mflv_3803|M.gilvum_PYR-GCK          MAAASPRKSRRTPGRHRKPSNHAHWLRVGAVGFGLAAAIISGQGVATADT
TH_3241|M.thermoresistible__bu      --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           ---------------------------------------MVDGAPSSDPE
MLBr_01022|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           --------------------------------------------------
Rv3439c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4382|M.avium_104                --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2591|M.vanbaalenii_PYR-1       GDASNSQDSSAGTGDTGDGGNTVEPGAGTVTSVEDEGSDPDEAPADDTQD
Mflv_3803|M.gilvum_PYR-GCK          DDSSGSGESSA----TARGKQAAVADRPSASEQSESPSSPD------SDN
TH_3241|M.thermoresistible__bu      --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           NEPTQREDLPDRLRVHSLARTLGTSSRRVLDALSALDGRIRSAHSSVDRV
MLBr_01022|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           --------------------------------------------------
Rv3439c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4382|M.avium_104                --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2591|M.vanbaalenii_PYR-1       DTEDVDDAVDPDGDDPTNDEPANDGAEPVDDESEPEPTEEPDEDTSPDTP
Mflv_3803|M.gilvum_PYR-GCK          DGVGTDDETTDDTDTDTGAESPDVEVDEQDQDPQPDTVEEPDEDTS-EVT
TH_3241|M.thermoresistible__bu      --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           DAVRVRDLLAEQPAEEGQAEEDQQAPDAVAAEVPDAPGEPAEPESRLMLE
MLBr_01022|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           --------------------------------------------------
Rv3439c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4382|M.avium_104                --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2591|M.vanbaalenii_PYR-1       ADDQEPAEPSQDPAT--PAPSTESSAP-EPEATESSALPESGSADTAEDS
Mflv_3803|M.gilvum_PYR-GCK          VDESDGSRTHQKPVVTETTPPAEASPPSTPADGTDAPQPETAPPATGGNK
TH_3241|M.thermoresistible__bu      --------------------------------------------------
MAB_2960|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           TQETVQVVETWVERPHYMPLFVAPQPISEPVAGDDADDESGDEGDDDEEQ
MLBr_01022|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           --------------------------------------------------
Rv3439c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4382|M.avium_104                --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2591|M.vanbaalenii_PYR-1       ADPVTTESPSSTG-------ADASDDGNATAESAVEVDPAQTAVIAMVKE
Mflv_3803|M.gilvum_PYR-GCK          ADPGTTPAPSSPGGSTGGPSTAAPDDEAATPETEAETEAAY--LLNFVKE
TH_3241|M.thermoresistible__bu      -----------------------------------------------VGA
MAB_2960|M.abscessus_ATCC_1997      --------------------------------------------------
MUL_3715|M.ulcerans_Agy99           ADRPGNRRRRRGRRGRGRGRGEQGANDGQDQPGDDGDEAPQKAGGNSTSS
MLBr_01022|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           --------------------------------------------------
Rv3439c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4382|M.avium_104                --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2591|M.vanbaalenii_PYR-1       LLKAIGITQTGGDGSSPLTSIDELIQGLWLAGRQDQQARATQRKAVAALV
Mflv_3803|M.gilvum_PYR-GCK          LVKVFGGATTDGGGTAPPMSWDKVLQGLFLG-RKDQET----RNATRELI
TH_3241|M.thermoresistible__bu      PPRSKEVMVNVTLGVFVESGTARIVLVDADPPNPVVDQTDLDLAAADSTP
MAB_2960|M.abscessus_ATCC_1997      -------------------------------------MTTVPSPAEDTAM
MUL_3715|M.ulcerans_Agy99           DDSEAQDGADSEESDNGDDDNGSADGASRRRRRRRRRKSGAGDDGDEGPA
MLBr_01022|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           ------------------------------------MADRLNVAERLAEG
Rv3439c|M.tuberculosis_H37Rv        ------------------------------------MADRLNVAERLAEG
MAV_4382|M.avium_104                ------------------------------------MADRLDVAGRLAEG
MMAR_2416|M.marinum_M               --MTATVLAYFPSPPRGVWHLGPLPIRAYAFFIIIGIVMGLMIGDRRFAA
MSMEG_3222|M.smegmatis_MC2_155      --MTTTVLAYLPSPSQGVWHLGPVPIRAYALCIIVGIVAALVIGDRRWQA
Mvan_2591|M.vanbaalenii_PYR-1       ELVSENSLAQLGTSIGWIPVVGTAVYGVSFLGNLVALGVAVLQGDGAEVA
Mflv_3803|M.gilvum_PYR-GCK          ELANEKTLAELGTSIGWVPFVGTGLYGASFVGNLGALISAVLRGDSADIA
TH_3241|M.thermoresistible__bu      DTLVTTVLATAGALTESGHRLVGISLCGPAADRIGPVHDALTGSGLRPVT
MAB_2960|M.abscessus_ATCC_1997      RMWEFPEENPEPPARWGKYVPGEPQLRAAAFGTLVGLLVAVLMGAAYAAQ
MUL_3715|M.ulcerans_Agy99           PDDPPNTVVHERAPRSGDKSGNSDSGDDSGGNEIKGIDGSTRLEAKRQRR
MLBr_01022|M.leprae_Br4923          -----MEQSRRVPPLQWLSAVARPIARVLTLISTPTFDIADTFGYACP--
                                                                        .             

Mb3469c|M.bovis_AF2122/97           RP----------------AAEHTQSYVR----------------------
Rv3439c|M.tuberculosis_H37Rv        RP----------------AAEHTQSYVR----------------------
MAV_4382|M.avium_104                RA----------------GVEHTQTYVQ----------------------
MMAR_2416|M.marinum_M               RGGERGVIYDIALWMVPFGLIGGRLYHL----------------------
MSMEG_3222|M.smegmatis_MC2_155      RGGEPGVIYDIALWAVPFGLAGGRIYHV----------------------
Mvan_2591|M.vanbaalenii_PYR-1       DELRDLGRDLIGMVPVVGAPVAGTLYADDAFPS-ATARMSTLAAAEPALA
Mflv_3803|M.gilvum_PYR-GCK          DEFRDLGRDVVGMVPVVGAPTAAKLYAGGSDAVGASAQMSAQLSAQ----
TH_3241|M.thermoresistible__bu      VVDESDAVTAVVRTLAGDETVATLVNDG----------------------
MAB_2960|M.abscessus_ATCC_1997      PGASLWALNKTIFPTHSQDIAVRAVVSDLKN-------------------
MUL_3715|M.ulcerans_Agy99           RDGRDAGRRRPPVLSEAEFLARREAVER----------------------
MLBr_01022|M.leprae_Br4923          ------------------NPPEVSPTEG----------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           ---------------------------ACHLVGYQHPD------------
Rv3439c|M.tuberculosis_H37Rv        ---------------------------ACHLVGYQHPD------------
MAV_4382|M.avium_104                ---------------------------ACHALGYQHPD------------
MMAR_2416|M.marinum_M               ---------------------------STDWQTYFGEG------------
MSMEG_3222|M.smegmatis_MC2_155      ---------------------------ITDWKTYFGPT------------
Mvan_2591|M.vanbaalenii_PYR-1       AVEPALAAAAAAPVGSQQHFLSVLQRAVSRLVGWPGTP-RNFVDVTNYQT
Mflv_3803|M.gilvum_PYR-GCK          -MTAMATATPPPPVGTQAHFLWVLQRAVNRLAGWPGPAGQNFVDITNRVT
TH_3241|M.thermoresistible__bu      ---------------------------ATVALSMTEAG------------
MAB_2960|M.abscessus_ATCC_1997      ---------------------------AQDILGNNKQP------------
MUL_3715|M.ulcerans_Agy99           -------------------------VMVVRDRVRTEPP------------
MLBr_01022|M.leprae_Br4923          ---------------------------VYVVATKTSP-------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           ---------------LTAYPAQIHDWYGSEDGLDLHALDADCAQLRAAAS
Rv3439c|M.tuberculosis_H37Rv        ---------------LTAYPAQIHDWYGSEDGLDLHALDADCAQLRAAAS
MAV_4382|M.avium_104                ---------------LTAHPAQVREWYAGEDGLDLRALDRDCAELRAAGV
MMAR_2416|M.marinum_M               ---------------GAGLGAALRIWDGGLGIWGAVTLGTVGAWIGCRRR
MSMEG_3222|M.smegmatis_MC2_155      ---------------GKGFGAALQIWEGGLGIWGAVAFGAVGAWIACRLR
Mvan_2591|M.vanbaalenii_PYR-1       DQTLDLANNQLDGLYANAPVGSQARWLPDMVSIVSLFFIPSVSGATFTDK
Mflv_3803|M.gilvum_PYR-GCK          DQTLDNADNQLDILIANAFAGSPAVWLPDLGRVLGLFVLTAIPGYSYTDS
TH_3241|M.thermoresistible__bu      ---------------GVTTPVATEPIDGDPQAAYRTLVERFAADPGAASG
MAB_2960|M.abscessus_ATCC_1997      --------------SPDQLTQARSSLNEAKQGLEFVSDSDERTSLQNLYL
MUL_3715|M.ulcerans_Agy99           --------------HPGSRYTQIAVLEDGIVVEHFVTSAASASLVGNIYL
MLBr_01022|M.leprae_Br4923          ---------------ATGQPVKRTATKTPATPAKRSTTKAANGSAPTKRA
                                                                                      

Mb3469c|M.bovis_AF2122/97           -VLMEALRMERSQVAVLAAAWTGSGADAAVHFVQR---------------
Rv3439c|M.tuberculosis_H37Rv        -VLMEALRMERSQVAVLAAAWTGSGADAAVHFVQR---------------
MAV_4382|M.avium_104                -VAAEALRLQRAQVAELAVAWTGAGGEAAVQLLQR---------------
MMAR_2416|M.marinum_M               GIPLPAFLDAVAPGVVMGQAIGRLGNYFNQELYGRETTVPWGLEIFYRRD
MSMEG_3222|M.smegmatis_MC2_155      GIPLPAFGDAIAPGIILAQGIGRLGNYFNQELYGRPTDVPWGLEIYERLN
Mvan_2591|M.vanbaalenii_PYR-1       LNAMGDFLNRVIPPFTIADGAGTFDIISPYKIMGAAVVGTATVLKDMLNG
Mflv_3803|M.gilvum_PYR-GCK          LNAWGSFLNKIMPPYKIADGAGTLDVISNYKITGAAVVGAATLLRDMLNG
TH_3241|M.thermoresistible__bu      LIVMGSLGDGGLPADLVETSPVPLRFPDDPEFMLARGATLASLS------
MAB_2960|M.abscessus_ATCC_1997      QLNQQLRQYTPEQAQQLPALPAPPGVNTDTNLAANIGPAAPASSPPPSWG
MUL_3715|M.ulcerans_Agy99           GIVQNVLPSMEAAFVDIGRGRNGVLYAGEVNWDAAGLGGADRKIEQALKP
MLBr_01022|M.leprae_Br4923          TSTASRATKSTTPPKASGASDAAKKARTSVKSVDTKAP------------
                                                                  .                   

Mb3469c|M.bovis_AF2122/97           -----HCETGNSVVTEVRAAAQRCESLRDNLW-QLVDS------------
Rv3439c|M.tuberculosis_H37Rv        -----HCETGNSVVTEVRAAAQRCESLRDNLW-QLVDS------------
MAV_4382|M.avium_104                -----HCDTAEALATELRAAAQRCESLRDNLW-YLIDA------------
MMAR_2416|M.marinum_M               PSGFVDVHSLDGVSTGQVAVVVQPTFLYELIW-NLLVFAAL---------
MSMEG_3222|M.smegmatis_MC2_155      --KFGQSDQLNGVSTGQVTAVVHPTFLYELIW-NIAVFGFL---------
Mvan_2591|M.vanbaalenii_PYR-1       IYDPVQIEIDVIKATTGATVTASDLNDQNALM-TKVALAQL-----GSDP
Mflv_3803|M.gilvum_PYR-GCK          IYDPVQWEINIIKTTTGATVTASDLNDFNTIM-TKVAAAQAGAILIGGDG
TH_3241|M.thermoresistible__bu      ----QDATMAAPVVADELPTTVTPLETADTMQ-SQQLAYSEVP-------
MAB_2960|M.abscessus_ATCC_1997      ---YATAASAPAPAAESYLVPPPAGIPVDPVP-DWPAPVAP---------
MUL_3715|M.ulcerans_Agy99           GDYIVVQVSKDPVGHKGARLTTQVSLAGRYLV-YVAGASSTG--------
MLBr_01022|M.leprae_Br4923          -----SAQDHTTKASAAKDTLNDPEATLNTLDSDAT--------------
                                                                  :                   

Mb3469c|M.bovis_AF2122/97           -------------KVATAIAIDERALAQRPAWLAAAEALTTEGADRPTAV
Rv3439c|M.tuberculosis_H37Rv        -------------KVATAIAIDERALAQRPAWLAAAEALTTEGADRPTAV
MAV_4382|M.avium_104                -------------KAATAIAVDDRTRAQRPEWLAAAAAVTAGQPDRDDAH
MMAR_2416|M.marinum_M               ------------IYLDRRFTIGHGRLFASYVALYCVGRFCVELLRDDTAT
MSMEG_3222|M.smegmatis_MC2_155      ------------IWVDRKFRIGHGRLFALYVASYCVGRFWVELMRSDTAT
Mvan_2591|M.vanbaalenii_PYR-1       GAFGEPTRAWNVTLPAWTEAQVNPYTLTVYVALVGIYKRFQEMAALTTFT
Mflv_3803|M.gilvum_PYR-GCK          GAFDDPTRAWNVTLPTWTEAQVNPYTITTYVALVAIYKRFQEMATLTTFT
TH_3241|M.thermoresistible__bu      ------------DEDSDLLGFTDPVDTPGADGPAGGFDPEAEDAEDADAE
MAB_2960|M.abscessus_ATCC_1997      ------------PLTPNLLDLGGYDPSWSLLYGYNVLDWFNWGLSGFNRY
MUL_3715|M.ulcerans_Agy99           --------ISRKLPDTERQRLKEILREVVPSDAGVIIRTASEGVKEDDIR
MLBr_01022|M.leprae_Br4923          --------------ADDLDAEPDLDVEPSEDIDIDIEAADLGLDDLEDDD
                                                                                      

Mb3469c|M.bovis_AF2122/97           EVVRQQIQPYVDDDVRNDWLTTMRSTTAG---------------------
Rv3439c|M.tuberculosis_H37Rv        EVVRQQIQPYVDDDVRNDWLTTMRSTTAG---------------------
MAV_4382|M.avium_104                NVIRQKVIPYVDNDIRNEWLTAMRSATDG---------------------
MMAR_2416|M.marinum_M               HIAGIRINSFTSTFVFIGAVVYIILAPKGREDPASVRGTAAAAEEVPEPE
MSMEG_3222|M.smegmatis_MC2_155      EFAGIRVNTFTSTFVFIGAVVYIMLAPKGREEPESLRGKAADETE-----
Mvan_2591|M.vanbaalenii_PYR-1       TWTTYDSWHYTNGLGMYAAGTFHAVDPDGGTIEFRADGTLGKTYTTEGNA
Mflv_3803|M.gilvum_PYR-GCK          TWTTYDSWHYTNALGMYAAGTFHAVDPDGGSIEFRADGTLGRTYTTEGNA
TH_3241|M.thermoresistible__bu      DAVRRRQWLIGSSVGALAAVGFATLAVSVAITIEPTSSQQAVRLQ-----
MAB_2960|M.abscessus_ATCC_1997      GYDFMGFDRWGYDRWGYDRWGYDRWGYNWDGYNWSGYNRDGRDRD-----
MUL_3715|M.ulcerans_Agy99           ADVTRLQERWNQIEAKAVEIKQKAAGAAVALYEEPDVLVKVIRDLFN---
MLBr_01022|M.leprae_Br4923          VVTDIEPGETEDGEATAATKTDEASTDDDEEIVEPTEK------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           ------------------------------------------VAASYDAV
Rv3439c|M.tuberculosis_H37Rv        ------------------------------------------VAASYDAV
MAV_4382|M.avium_104                ------------------------------------------VQTSYAMV
MMAR_2416|M.marinum_M               PAGEVATAA-----------APAGDTEGDEPTGLAETAKAAEVAEPETVG
MSMEG_3222|M.smegmatis_MC2_155      --------------------------EGDEESLVDEAGKELVAAA---AG
Mvan_2591|M.vanbaalenii_PYR-1       LVTINTVGGGFTYTPPAIWDPKFQNAAFFHRSTAEDPEERFDWVTVEAYS
Mflv_3803|M.gilvum_PYR-GCK          LVTINTVGGGFTYTPPALWDPQAQGAAFRHRSTAEDPEERFDWVTVDAYS
TH_3241|M.thermoresistible__bu      --------------------------------EGPVPGKAFPVAPGQGVE
MAB_2960|M.abscessus_ATCC_1997      -----------------------------------------GRNEWGQIH
MUL_3715|M.ulcerans_Agy99           ----------------------------------------EDFAGLVVSG
MLBr_01022|M.leprae_Br4923          -----------------------------------------DKASGDFVW
                                                                                      

Mb3469c|M.bovis_AF2122/97           TDQLASAPRAHFEIPDDLGPGRQPSPAS----------------------
Rv3439c|M.tuberculosis_H37Rv        TDQLASAPRAHFEIPDDLGPGRQPSPAS----------------------
MAV_4382|M.avium_104                VDRMAAAPAARFELPGDLGSGLVPVPATRPLVAAPMP-------------
MMAR_2416|M.marinum_M               SAVAGDESTADTEASDAVESEVGEAAEAEAPEAEAEEAEVGEVEVAEAVE
MSMEG_3222|M.smegmatis_MC2_155      TGVVAAATAAAREDTDDTDGTTDPAAASDEPGDEAEP----ETEAATAVL
Mvan_2591|M.vanbaalenii_PYR-1       ADGVPINIRVGIEIIDGTNAAPTYSGITGQNTDALGVVKGKITGSDSDGD
Mflv_3803|M.gilvum_PYR-GCK          ADGVPYSLRMGIEIIDGTNAVPVYTGVTGQSTDALGVVKGKLNATDSDGD
TH_3241|M.thermoresistible__bu      PDGPNWTMIEHLPPPGAPAEVRTFETRALSSSRDVSKAAAPAIVNVYRDG
MAB_2960|M.abscessus_ATCC_1997      DDDPRDQGWYDRYHPYRQYYDWKFQNTNPVYSRSLWDQSHGIDPSQYRDW
MUL_3715|M.ulcerans_Agy99           DDAWDTINEYVSSVAPDLVSKLSKYEPAVGSEGQVGPDVFAVHRIDEHLA
MLBr_01022|M.leprae_Br4923          DEDESEALRQARKDAELTASADSVRAYLKQIGKVALLN------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           ----------------VPAQPSATAAITPAAALPPPDP-----VPAVTSR
Rv3439c|M.tuberculosis_H37Rv        ----------------VPAQPSATAAITPAAALPPPDP-----VPAVTSR
MAV_4382|M.avium_104                -----PLDAAPTLPDAAPTLPAAVSEPAAAATLPAAAP-----TPAAVPP
MMAR_2416|M.marinum_M               GEVEEAEEAEPGEVEVAEAVEGEVEAAAEAEEAEEAEE-----AEEAEEA
MSMEG_3222|M.smegmatis_MC2_155      ----TADGAEAMSVDEQPDDDEAVDEEAGQEAEEPADE-----LVELADE
Mvan_2591|M.vanbaalenii_PYR-1       PLRYYLVESSVNGLSGNSAYTKNGAGNGGIVTVSENGD-----FTYVSNG
Mflv_3803|M.gilvum_PYR-GCK          PIRYYLVESSVNGLNGNSAYTKNGAGNGGIVTVNENGD-----FTYVSSA
TH_3241|M.thermoresistible__bu      TVAVQNAAAPLLPVGPAPALPGTVPVTVPGPVFAEWPEYVTRLIPDFSRI
MAB_2960|M.abscessus_ATCC_1997      NLNRNWDNPLERDWSPVARVADRPLLAEPVVNLDASLAQ---FITDDKSA
MUL_3715|M.ulcerans_Agy99           KAMDRKVWLPSGGTLVIDRTEAMTVVDVNTGKFTGSGGN----LEQTVTK
MLBr_01022|M.leprae_Br4923          ---------AEEEVELAKRIEAGLYATQLMTELSERGTK---LPTAQRRD
                                                                                      

Mb3469c|M.bovis_AF2122/97           PVTP----SDFGSAPGDGSATPAG-VGSAGGFGDAGGTG-GLGGFAGLAG
Rv3439c|M.tuberculosis_H37Rv        PVTP----SDFGSAPGDGSATPAG-VGSAGGFGDAGGTG-GLGGFAGLAG
MAV_4382|M.avium_104                AAAAPA--ADWGAALGDVAGMPAGDLGGLAESGMGSGLGSGLGGGGGLLG
MMAR_2416|M.marinum_M               EEAEPGEIEVAEAVEGEVEAAAEAEEAEVGEVEAVDEAAEAEAPEVGEIE
MSMEG_3222|M.smegmatis_MC2_155      PEGEP---EPAAAEEAEPAETIEPDEDEIFDAELAEALAEAAEDFAVVPE
Mvan_2591|M.vanbaalenii_PYR-1       TAGATQSFQVRINDGHHGNTIVTVTVTNTTSITPANVNTSTQNVVTGTVP
Mflv_3803|M.gilvum_PYR-GCK          TAGATQSFQVRVNDAHHGNTIVTVTVPNTTSITPGNVNTSTPYVVTGTVP
TH_3241|M.thermoresistible__bu      RPVDLLYFLANLRELLPPLEATTPDPDDGFDIGDIGVLAVVPRDQGVLFS
MAB_2960|M.abscessus_ATCC_1997      RSSQDLIKDLSNKSARNFSKELAAQTPRPDRSTGPDAPAAVKPAAPPVLT
MUL_3715|M.ulcerans_Agy99           NNLEAAEEIVRQLRLRDIGGIVVIDFIDMVLESNRDLVLRRLTEALARDR
MLBr_01022|M.leprae_Br4923          MMWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGLIR
                                                                                      

Mb3469c|M.bovis_AF2122/97           LANRIVDAVDSLLGSVAEQLG--DPLAADNPPG----AVDPF-AEDAADN
Rv3439c|M.tuberculosis_H37Rv        LANRIVDAVDSLLGSVAEQLG--DPLAADNPPG----AVDPF-AEDAADN
MAV_4382|M.avium_104                LAGKIVDAMGGLLGSVGDGLDGSDPFGDQDPLDDNAFHGDPFHADDPADA
MMAR_2416|M.marinum_M               AAEAVEGEVEVAAEAEEAEAGEDEPKEAEEVAEAEGSEAEDKTVQAIDGG
MSMEG_3222|M.smegmatis_MC2_155      SAGSDEAEVAAAESAADAEDGPSDAESAEVPAEAA---ADDAVVSEPAG-
Mvan_2591|M.vanbaalenii_PYR-1       NSTNKPGAFVSYTLGSSPTKGSVTSFDPTTGAFTYVRDSGLGHGTTPDDF
Mflv_3803|M.gilvum_PYR-GCK          ASTNKPGAFTSYTLVGGTTKGTVTSFNPVTGAFTYT--SSVGRVLDNDDV
TH_3241|M.thermoresistible__bu      ADADAAGPEMIPARLFDPQTPAADKTQLLPPGTTVLDVPTDGDGDDPTAA
MAB_2960|M.abscessus_ATCC_1997      APVPVVPPKEVPADFTPPSLPPVAPVTPAPRTTSSAPSSAPSTEPSHTPE
MUL_3715|M.ulcerans_Agy99           TRHQVSEVTSLGLVQLTRKRLGTGLIEAFSTSCPHCSGRGILLHADPVDS
MLBr_01022|M.leprae_Br4923          AVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIPVHMVEVINKLG
                                                                                      

Mb3469c|M.bovis_AF2122/97           -----ADDGDD--------AHPEEADEAAEPKEATEPDEADEVDD---AD
Rv3439c|M.tuberculosis_H37Rv        -----ADDGDD--------AHPEEADEAAEPKEATEPDEADEVDD---AD
MAV_4382|M.avium_104                -----KDAGDD--------ADETAADEPGAPD---RPAPAGEAEP---SG
MMAR_2416|M.marinum_M               QTGVDDAGEAD--------AEPDDDSTAAEPEVVVEQADIEEIEPQEPEA
MSMEG_3222|M.smegmatis_MC2_155      -----TVDETE--------VAEEAAAEAADLEFESYDAELAEALAEAAED
Mvan_2591|M.vanbaalenii_PYR-1       VTVIATDADGRQVTLRM--AVAPTVSNAGPTVVLTTQPTVGTLSGTTQTS
Mflv_3803|M.gilvum_PYR-GCK          ITVIGTDADGRSVTLRL--NVKPTTVTVAPTLTLTTAPTVGTLVGTTQTS
TH_3241|M.thermoresistible__bu      LTGEPTTGDTDESRSQRPGMDTEPAGTPEDSDSDADAGDGSVVDETGVDE
MAB_2960|M.abscessus_ATCC_1997      PSSEPPANGTT--------SNPGPTPTSVAPAPTQKDESSAPVTTAVTPT
MUL_3715|M.ulcerans_Agy99           APTTGRKADSGGRRNRR--SKKNRAEEPSEKEAVAKVPTYAPGEHPMFKA
MLBr_01022|M.leprae_Br4923          RIQRELLQDLG----------REPTPEELAKEMDITPEKVLEIQQYAREP
                                                                                      

Mb3469c|M.bovis_AF2122/97           ESVPAERAQDVA-------------------EEATLPPVAEPPPPAAP--
Rv3439c|M.tuberculosis_H37Rv        ESVPAERAQDVA-------------------EEATLPPVAEPPPPAAP--
MAV_4382|M.avium_104                EPAPSGEAAPTG-------------------EPAQP---VEATPPAAP--
MMAR_2416|M.marinum_M               EAVAAAEATDADEGDGEPAEPASDDLDAVAAEDADVDVDATATEAEESGD
MSMEG_3222|M.smegmatis_MC2_155      MAVVVAPAETAE------------------SDEAREPVETDATESEEP--
Mvan_2591|M.vanbaalenii_PYR-1       TGKLTYSDPDGDAPVWTT-ATSSRGATITFAADGTFTYTSNLTVAQRHAV
Mflv_3803|M.gilvum_PYR-GCK          TGKFTYFDADGDAPIWPTSVTSSRGGTVTVAADGTFTYTSNLTVAQRHAV
TH_3241|M.thermoresistible__bu      TGPAPDSGPDSG-------------------PGSEPTEVTHPTPPAEPTV
MAB_2960|M.abscessus_ATCC_1997      HETPATTAPRQT-------------------ATVPPSQPVEPTTAPEPTK
MUL_3715|M.ulcerans_Agy99           MAASSSSEAEHGDGE--------------VEESGEELTAAVDDQTAVQVA
MLBr_01022|M.leprae_Br4923          ISLDQTIGDEGD------------------SQLGDFIEDSEAVVAVDAVS
                                                                                .     

Mb3469c|M.bovis_AF2122/97           ----PVAEPPPPVAAPAP-----------------------PGAPEPANG
Rv3439c|M.tuberculosis_H37Rv        ----PVAEPPPPVAAPAP-----------------------PGAPEPANG
MAV_4382|M.avium_104                ----PPAAPPP-GAPPAD-----------------------PGPAPAAAQ
MMAR_2416|M.marinum_M               ESPEPAADSEEPEADESAPEDSAEDTSS--GESDTQSELEQSQTIEQGSD
MSMEG_3222|M.smegmatis_MC2_155      ------SEPEEPDAPEAV---------------------EAPEALDENAD
Mvan_2591|M.vanbaalenii_PYR-1       ARIGAAGSTYNGVALAAWEDAFTATVSDGFGGTAQVTVKVPIYAINANPT
Mflv_3803|M.gilvum_PYR-GCK          ARIGAAGSTFNGVALAAWEDAFAMTVSDGFGGTATQTVKVPIYAINANPT
TH_3241|M.thermoresistible__bu      APDEPTSRPSTSAPAPAPDPDTPTQAPAVQAPPASQEPATRAPATQAPAT
MAB_2960|M.abscessus_ATCC_1997      QHSTPTHDVPTSEAPAPR---------------------ATAEPAPAEPP
MUL_3715|M.ulcerans_Agy99           LDLGETEESEETDGTDETDDFDDDSDDSDDSDEDDDTDETNDTDVDADED
MLBr_01022|M.leprae_Br4923          FTLLQDQLQSVLETLSER----------------------EAGVVRLRFG
                                                                                      

Mb3469c|M.bovis_AF2122/97           PSPEALSEGATPCEIAADELPQAGP-------------------------
Rv3439c|M.tuberculosis_H37Rv        PSPEALSEGATPCEIAADELPQAGP-------------------------
MAV_4382|M.avium_104                PTPEP---GSTPCQIAADQLPQAGQ-------------------------
MMAR_2416|M.marinum_M               QTSAGDGEGPPPSAAVDGDTGPTRQGWRGRLRNRMRRSGR----------
MSMEG_3222|M.smegmatis_MC2_155      ETRA---EPAAPAAVATAPVEPE----KGRLRRWLRRNR-----------
Mvan_2591|M.vanbaalenii_PYR-1       IGTNSPACGFGTCTVTATTTDPDGDDLSGSLNTSNNGNGDPWYTLARGSV
Mflv_3803|M.gilvum_PYR-GCK          LGLGGLACGFGTCTITITTTDPDGDDLSGSLNTSNNGQGDPWYTLERGSV
TH_3241|M.thermoresistible__bu      QAPATQAPGTQEPITQAPATEEPATQAPVTQGPATQAPRTVAPQTQAPET
MAB_2960|M.abscessus_ATCC_1997      AKQAPAERETPPSRTAAPEPAAPTREAPAREAPTREAPSYSTATQAPSAG
MUL_3715|M.ulcerans_Agy99           EDTDDDSDEDEDTEDDDELDDDLDDELDDDDSDSDDEDSESELTEPAAGR
MLBr_01022|M.leprae_Br4923          LTDGQPRTLDEIGQVYGVTRERIRQIESKTMSKLRHPSRSQVLRDYLD--
                                                                                      

Mb3469c|M.bovis_AF2122/97           --------------------------------------------------
Rv3439c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_4382|M.avium_104                --------------------------------------------------
MMAR_2416|M.marinum_M               --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155      --------------------------------------------------
Mvan_2591|M.vanbaalenii_PYR-1       TINAGNQHTFSWTGNSNGLGTQQTGIQIYTVYDGHYRVTNGVVDTSYFAR
Mflv_3803|M.gilvum_PYR-GCK          TINAGNQHTMSWTGNSGGLGTQQTGVQRYTVYDGYYRVTNGVVDSSYFAR
TH_3241|M.thermoresistible__bu      VAPQVEAPVTTMPQYPVGGGSFGGGADGD---------------------
MAB_2960|M.abscessus_ATCC_1997      GG--------------NSGGGSGGGRH-----------------------
MUL_3715|M.ulcerans_Agy99           PAALEVTTIAERPRRRRAAGRPAGPPIHLG--------------------
MLBr_01022|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb3469c|M.bovis_AF2122/97           --------------
Rv3439c|M.tuberculosis_H37Rv        --------------
MAV_4382|M.avium_104                --------------
MMAR_2416|M.marinum_M               --------------
MSMEG_3222|M.smegmatis_MC2_155      --------------
Mvan_2591|M.vanbaalenii_PYR-1       AWVQWNNTTRTFGN
Mflv_3803|M.gilvum_PYR-GCK          AWVNWNNTTRTTGN
TH_3241|M.thermoresistible__bu      --------------
MAB_2960|M.abscessus_ATCC_1997      --------------
MUL_3715|M.ulcerans_Agy99           --------------
MLBr_01022|M.leprae_Br4923          --------------