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TGRRRVRIDVRGVVQGVGFRPFVYTRATALGLSGSVRNDSTGAIVEIEGAADDIDRFLARLHDHPPPLAV VESVDVRSVPLSGGTGFAIADTSRTDGGRTLASPDVAMCADCAAELRDPRNRRFRHPFINCTNCGPRFTI IAALPYDRSSTTMADFPMCADCAGEYTDPTDRRFHAQPICCPGCGPTLRYRDGDGRDTDGEPGLLAARRL LRDGGVLAVKGVGGYHLACDASDRRAVAALRARKRRGDKPFAVMVPDIDAARAIADVDPASAALLRGPAR PIVLMQRRAGAAVDAAVAPHNPDLGVLLTYTPLHALLLGLDGDGPGPQVLVMTSGNLGGEPICFTEDAAF ERLSCLADGWLWHDRAILVPCDDSVVRADMPVRRSRGYAPLPIALPVAVSPTLAVGADLKNTMAVADGRY AWLSQHIGDMDDLATLSVFDAAQQHLRRLTAVEPEVLVADAHPLYRSTAWAHRNAAGRPVRSVQHHHAHI AAVMAEHGMDGSAPVLGFAFDGTGYGPDGAVWGGEVLLADYKGFQRLARLRYVPLAGGDVSVLRPYRMAL THLWAAGLPWTPDLAPVRACPAAEQRVLRHQLETGLGCAPTSSMGRLFDAVSALAGVRQVVDYEAQAAIE LEGLARDVGCNADGYRFTVDREPPTAEIDPAPVLAAVVGDVGSGVGSGVVGARFHHAVARLILDLAVEHR GYPVALSGGVFQNALLLRTAQTLLVDNGFEVITHRHVPPNDGGIALGQLIVGNTA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2407 | - | - | 100% (756) | (NiFe) hydrogenase maturation protein HypF |
| M. vanbaalenii PYR-1 | Mvan_2359 | - | e-178 | 49.16% (771) | (NiFe) hydrogenase maturation protein HypF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3979 | - | 0.0 | 77.59% (754) | (NiFe) hydrogenase maturation protein HypF |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1862 | hypF | 0.0 | 50.52% (766) | hydrogenase maturation factor, HypF |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2711 | hypF | 0.0 | 69.86% (763) | [NiFe] hydrogenase maturation protein HypF [Mycobacterium |
| M. thermoresistible (build 8) | TH_1524 | hypF | 1e-46 | 64.71% (136) | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2407|M.vanbaalenii_PYR-1 ------------MTGRRRVRIDVRGVVQGVGFRPFVYTRATALGLSGSVR
Mflv_3979|M.gilvum_PYR-GCK ------------MTARRRVHAGVRGVVQGVGFRPFVYTQATLLGLSGWVR
MSMEG_2711|M.smegmatis_MC2_155 ------------MTARLRLRIDVHGVVQGVGFRPFVYTTAAAMGLTGHVR
MMAR_1862|M.marinum_M MAGLPLLRPAMVRCAETRQRFTVTGVVQGVGFRPFVHQLASELGLSGFVG
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mvan_2407|M.vanbaalenii_PYR-1 NDSTGAIVEIEGAADDIDRFLARLHDHPPPLAVVESVDVRSVPLSGG-TG
Mflv_3979|M.gilvum_PYR-GCK NDSSGAIIEVEGGNDALERFLDVLRHHPPPLAVIDSIDVRYIAVTGG-TG
MSMEG_2711|M.smegmatis_MC2_155 NDSSGAIIEIEGDEGDLERFLQRLHGGPPPLAVIESVEVRRITTVGG-TG
MMAR_1862|M.marinum_M NDSAAVFIEVQGGRAGLDEFARRLRADAPPLAGISSVSATELALQAGAAG
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mvan_2407|M.vanbaalenii_PYR-1 FAIADTSRTDGGRTLASPDVAMCADCAAELRDPRNRRFRHPFINCTNCGP
Mflv_3979|M.gilvum_PYR-GCK FTIVDTSRTDGGRTLASPDVAMCAECAAEQRDPRNRRYRHAFVNCTNCGP
MSMEG_2711|M.smegmatis_MC2_155 FRITDTSRADGGRTLVSPDVAMCRDCAAEQRDPANRRHRHAFINCTNCGP
MMAR_1862|M.marinum_M FRIVASQGATGATTPIPPDIAVCDDCVRELFDPRDRRFRHPFVTCTNCGP
TH_1524|M.thermoresistible__bu --------------------------VAELFDPADRRYRHPFITCTDCGP
. * ** :**.**.*:.**:***
Mvan_2407|M.vanbaalenii_PYR-1 RFTIIAALPYDRSSTTMADFPMCADCAGEYTDPTDRRFHAQPICCPGCGP
Mflv_3979|M.gilvum_PYR-GCK RFTLIASLPYDRASTTMAEFEMCADCAREYHDPADRRFHAQPICCPGCGP
MSMEG_2711|M.smegmatis_MC2_155 RFTIIASLPYDRASTTMAGFPMCTECAREYRDPDDRRFHAQPVCCPNCGP
MMAR_1862|M.marinum_M RLTVIRTLPYDRPGTTMSAFPMCERCAAEYHDPGDRRFHAQPIACPNCGP
TH_1524|M.thermoresistible__bu RFTIIKALPYDRPATTMADFPMCDRCAEEYHDPTDRRFHAQPISCPDCGP
*:*:* :*****..***: * ** ** ** ** ********:.**.***
Mvan_2407|M.vanbaalenii_PYR-1 TLRYRDGDG---RDTDGEPGLLAARRLLRDGGVLAVKGVGGYHLACDASD
Mflv_3979|M.gilvum_PYR-GCK TLRYRDRAG---RELAGESGLRAARRMLRAGKIVAVKGIGGYHLACDATG
MSMEG_2711|M.smegmatis_MC2_155 TLRLLTTEG---EHATGEHALQRARQLLATGGIVAVKGIGGYHLACDAAN
MMAR_1862|M.marinum_M SLWFRSATE---HVAGADAALAATQHALTAAKVVAIKGIGGYHLACAVDD
TH_1524|M.thermoresistible__bu RLGFRRGDQPVPDTHHTDAAISAAQGALAEGAVVAVKGIGGYHLACRADD
* : .: :: * . ::*:**:******* . .
Mvan_2407|M.vanbaalenii_PYR-1 RRAVAALRARKRRGDKPFAVMVPDIDAARAIADVDPASAALLRGPARPIV
Mflv_3979|M.gilvum_PYR-GCK PRAVTTLRARKRRGDKPFAVMVPDLDAARRVAEVDPASAALLTGPARPIV
MSMEG_2711|M.smegmatis_MC2_155 RVSVAELRHRKRRGDKPFAVMVADLATARAVAEVGDVAARLLCGPQRPIV
MMAR_1862|M.marinum_M DAVVGVLRSCKSRGAKPFAILVRDLDVARRYAFIDDAEAAVLSGPARPIV
TH_1524|M.thermoresistible__bu EDVVRALRSRKHRX------------------------GXXXQRPVGRIG
* ** * * . * *
Mvan_2407|M.vanbaalenii_PYR-1 LMQRRAGAAVDAAVAPHNPDLGVLLTYTPLHALLLG--LDGDGPGPQVLV
Mflv_3979|M.gilvum_PYR-GCK LMPRRAGAAVADAVAPHNPDLGVVLAYAPLHTLLFG--FGGDEPAPQTLV
MSMEG_2711|M.smegmatis_MC2_155 LIPRRSETLVCPEVSPHNPDLGVMLAYSPLHALLFG--LPGDPPGPAALV
MMAR_1862|M.marinum_M LLRRRPDAPVADAVASGSPLLGLMLPYSPIHHLLLAPVPGADAAAPEALV
TH_1524|M.thermoresistible__bu LGRGR---------------LGGRLGFP----------------------
* * ** * :.
Mvan_2407|M.vanbaalenii_PYR-1 MTSGNLGGEPICFTEDAAFERLSCLADGWLWHDRAILVPCDDSVVR----
Mflv_3979|M.gilvum_PYR-GCK MTSGNVAGEPICFTDDDAWQRLRPLADGWLYHDRAILVPCDDSVMR----
MSMEG_2711|M.smegmatis_MC2_155 MTSANLSGEPICFADDDALQRLSGLADAWLTHDRAILVPCDDSVVRVVDD
MMAR_1862|M.marinum_M LTSANRSDEPICFTESDAAERLSMLCDAVLDHDRPIHVPCDDSVVRVVED
TH_1524|M.thermoresistible__bu -------------------ARLRRRVPGR---------------------
** .
Mvan_2407|M.vanbaalenii_PYR-1 ----ADMPVRRSRGYAPLPIAL---PVAVSPTLAVGADLKNTMAVADGRY
Mflv_3979|M.gilvum_PYR-GCK ----ADTAIRRSRGYAPLPVAL---PVALAPTLAVGADIKNTMAVADGRY
MSMEG_2711|M.smegmatis_MC2_155 D-EVSEMAIRRSRGYAPLPVAL---PVPVVPTLAVGADLKNTVAVGDHEY
MMAR_1862|M.marinum_M AGLARELPIRRSRGYAPLPVDLGHIAVESPPVLAVGGELKNTFCLTDGTR
TH_1524|M.thermoresistible__bu ---------RRASGQGDQ----------------QGGDEQ----------
**: * . *.: :
Mvan_2407|M.vanbaalenii_PYR-1 AWLSQHIGDMDDLATLSVFDAAQQHLRRLTAVEPEVLVADAHPLYRSTAW
Mflv_3979|M.gilvum_PYR-GCK AWVSQHIGDMDDAATLSAFDSTRRHLEQLTRVDPELLVADAHPAYRSTAW
MSMEG_2711|M.smegmatis_MC2_155 AWLSGYIGDMDDLAALSAFDRAVTHLQALTGTTPRMLAADAHPGYRSTAW
MMAR_1862|M.marinum_M AYLSGHIGDMATWETLRAFERAVGQLSEIRG-HPVRLAADLHPGYHTRNW
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mvan_2407|M.vanbaalenii_PYR-1 AHRNAAGRPVRSVQHHHAHIAAVMAEHGMDGSAPVLGFAFDGTGYGPDGA
Mflv_3979|M.gilvum_PYR-GCK AHRNAAGRPVRTVAHHHAHIAAVMAEHGLDGDEPVLGFAFDGTGYGPDGA
MSMEG_2711|M.smegmatis_MC2_155 AHRNAGGRPVRSVQHHHAHIAAVMAEHGLDGSARVLGIAFDGTGFGSDGA
MMAR_1862|M.marinum_M AERHADDRPLDLIQHHHAHVVSLLAEHGR-INEPVVGVSFDGTGYGCDET
TH_1524|M.thermoresistible__bu --RETAGKTLR---------------------------------FG-DCR
*.: .:.: :* *
Mvan_2407|M.vanbaalenii_PYR-1 VWGGEVLLADYKG--FQRLARLRYVPLAGGDVSVLRPYRMALTHLWAAGL
Mflv_3979|M.gilvum_PYR-GCK VWGGEVLLADYKG--YQRLARLRYVPLAGGDVSVKRPYRMALAHLWAAGL
MSMEG_2711|M.smegmatis_MC2_155 VWGGEVLLADYKG--FERIAHLAYVPLAGGDVSVRRPYRMALSHLWAAGI
MMAR_1862|M.marinum_M IWGGEILVLGPQSHRFTRAGHLLAVPLPGGDAAVRNPWRMALSQLWTAHI
TH_1524|M.thermoresistible__bu AWRGRVDVLAGQG-----------IPP---DDRVNR--------------
* *.: : :. :* * * .
Mvan_2407|M.vanbaalenii_PYR-1 PWTPDLAPVRACPAAEQRVLRHQLETGLGCAPTSSMGRLFDAVSALAGVR
Mflv_3979|M.gilvum_PYR-GCK PWDRDLAPVRSCPAEELSVLRHQLETGLGCVPTSSMGRLFDAVSALAGVR
MSMEG_2711|M.smegmatis_MC2_155 PWDADLPPVRACPEGERRALCGQLNTGTGCVPTSSMGRLFDAVSALIGLR
MMAR_1862|M.marinum_M EWSPDLAPVAAAGVDELRVTRSQLASGAGCVPCSSMGRLFDAVASLLGVR
TH_1524|M.thermoresistible__bu ---------------------------------SRPGRLHPHVQ------
* ***. *
Mvan_2407|M.vanbaalenii_PYR-1 QVVDYEAQAAIELEGLARDVGCNADGYRFTVDREPPT-AEIDPAPVLAAV
Mflv_3979|M.gilvum_PYR-GCK QVVGYEAQAAIELEGLSRHENCGDTRYRFGIGTGSSP-VDLDPAPVLAAV
MSMEG_2711|M.smegmatis_MC2_155 QTVDYEAQAAIELEGQARHTPTGATAYAFAMHINRRP-VTFDAAPVLAAV
MMAR_1862|M.marinum_M HRIDYEGQAAIELEALAESALAECNGPRPSLPLTVRPDGVIDPTTMVQTL
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mvan_2407|M.vanbaalenii_PYR-1 VGDVGSGVGSGVVGARFHHAVARLILDLAVEHRGYP--VALSGGVFQNAL
Mflv_3979|M.gilvum_PYR-GCK VADAGRGIAPGVIGARFHRAVAALIADLASMSPGYR--VALSGGVFQNRL
MSMEG_2711|M.smegmatis_MC2_155 IADLRTHVPPAVISARFHQAVADLVVDLARLAAGGP--VALTGGVFQNAL
MMAR_1862|M.marinum_M VSALRAGTPPPVLAASFHQAVARAVAEVVAQVAGQVRLVGLTGGVFQNVL
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mvan_2407|M.vanbaalenii_PYR-1 LLRTAQTLLVDNGFEVITHRHVPPNDGGIALGQLIVGNTA----------
Mflv_3979|M.gilvum_PYR-GCK LLQLAQDMLRANGFDVLTHRHVPPNDGGIALGQLMIGNAV----------
MSMEG_2711|M.smegmatis_MC2_155 LLRLTLAGLRDSGIHALTACRVPPNDGGLALGQLLVGNAG----------
MMAR_1862|M.marinum_M LLRACRERLQRKGFEVLTHHTVPPNDGGLALGQAVVSLLIGLDEDWKRTD
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mvan_2407|M.vanbaalenii_PYR-1 -
Mflv_3979|M.gilvum_PYR-GCK -
MSMEG_2711|M.smegmatis_MC2_155 -
MMAR_1862|M.marinum_M R
TH_1524|M.thermoresistible__bu -