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AGLPLLRPAMVRCAETRQRFTVTGVVQGVGFRPFVHQLASELGLSGFVGNDSAAVFIEVQGGRAGLDEFA RRLRADAPPLAGISSVSATELALQAGAAGFRIVASQGATGATTPIPPDIAVCDDCVRELFDPRDRRFRHP FVTCTNCGPRLTVIRTLPYDRPGTTMSAFPMCERCAAEYHDPGDRRFHAQPIACPNCGPSLWFRSATEHV AGADAALAATQHALTAAKVVAIKGIGGYHLACAVDDDAVVGVLRSCKSRGAKPFAILVRDLDVARRYAFI DDAEAAVLSGPARPIVLLRRRPDAPVADAVASGSPLLGLMLPYSPIHHLLLAPVPGADAAAPEALVLTSA NRSDEPICFTESDAAERLSMLCDAVLDHDRPIHVPCDDSVVRVVEDAGLARELPIRRSRGYAPLPVDLGH IAVESPPVLAVGGELKNTFCLTDGTRAYLSGHIGDMATWETLRAFERAVGQLSEIRGHPVRLAADLHPGY HTRNWAERHADDRPLDLIQHHHAHVVSLLAEHGRINEPVVGVSFDGTGYGCDETIWGGEILVLGPQSHRF TRAGHLLAVPLPGGDAAVRNPWRMALSQLWTAHIEWSPDLAPVAAAGVDELRVTRSQLASGAGCVPCSSM GRLFDAVASLLGVRHRIDYEGQAAIELEALAESALAECNGPRPSLPLTVRPDGVIDPTTMVQTLVSALRA GTPPPVLAASFHQAVARAVAEVVAQVAGQVRLVGLTGGVFQNVLLLRACRERLQRKGFEVLTHHTVPPND GGLALGQAVVSLLIGLDEDWKRTDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_1862 | hypF | - | 100% (796) | hydrogenase maturation factor, HypF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_3979 | - | 0.0 | 50.26% (770) | (NiFe) hydrogenase maturation protein HypF |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2711 | hypF | 0.0 | 50.72% (769) | [NiFe] hydrogenase maturation protein HypF [Mycobacterium |
| M. thermoresistible (build 8) | TH_1524 | hypF | 1e-50 | 65.69% (137) | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2407 | - | 0.0 | 50.52% (766) | (NiFe) hydrogenase maturation protein HypF |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3979|M.gilvum_PYR-GCK ------------MTARRRVHAGVRGVVQGVGFRPFVYTQATLLGLSGWVR
Mvan_2407|M.vanbaalenii_PYR-1 ------------MTGRRRVRIDVRGVVQGVGFRPFVYTRATALGLSGSVR
MSMEG_2711|M.smegmatis_MC2_155 ------------MTARLRLRIDVHGVVQGVGFRPFVYTTAAAMGLTGHVR
MMAR_1862|M.marinum_M MAGLPLLRPAMVRCAETRQRFTVTGVVQGVGFRPFVHQLASELGLSGFVG
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK NDSSGAIIEVEGGNDALERFLDVLRHHPPPLAVIDSIDVRYIAVTGG-TG
Mvan_2407|M.vanbaalenii_PYR-1 NDSTGAIVEIEGAADDIDRFLARLHDHPPPLAVVESVDVRSVPLSGG-TG
MSMEG_2711|M.smegmatis_MC2_155 NDSSGAIIEIEGDEGDLERFLQRLHGGPPPLAVIESVEVRRITTVGG-TG
MMAR_1862|M.marinum_M NDSAAVFIEVQGGRAGLDEFARRLRADAPPLAGISSVSATELALQAGAAG
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK FTIVDTSRTDGGRTLASPDVAMCAECAAEQRDPRNRRYRHAFVNCTNCGP
Mvan_2407|M.vanbaalenii_PYR-1 FAIADTSRTDGGRTLASPDVAMCADCAAELRDPRNRRFRHPFINCTNCGP
MSMEG_2711|M.smegmatis_MC2_155 FRITDTSRADGGRTLVSPDVAMCRDCAAEQRDPANRRHRHAFINCTNCGP
MMAR_1862|M.marinum_M FRIVASQGATGATTPIPPDIAVCDDCVRELFDPRDRRFRHPFVTCTNCGP
TH_1524|M.thermoresistible__bu --------------------------VAELFDPADRRYRHPFITCTDCGP
. * ** :**.**.*:.**:***
Mflv_3979|M.gilvum_PYR-GCK RFTLIASLPYDRASTTMAEFEMCADCAREYHDPADRRFHAQPICCPGCGP
Mvan_2407|M.vanbaalenii_PYR-1 RFTIIAALPYDRSSTTMADFPMCADCAGEYTDPTDRRFHAQPICCPGCGP
MSMEG_2711|M.smegmatis_MC2_155 RFTIIASLPYDRASTTMAGFPMCTECAREYRDPDDRRFHAQPVCCPNCGP
MMAR_1862|M.marinum_M RLTVIRTLPYDRPGTTMSAFPMCERCAAEYHDPGDRRFHAQPIACPNCGP
TH_1524|M.thermoresistible__bu RFTIIKALPYDRPATTMADFPMCDRCAEEYHDPTDRRFHAQPISCPDCGP
*:*:* :*****..***: * ** ** ** ** ********:.**.***
Mflv_3979|M.gilvum_PYR-GCK TLRYRDRAG---RELAGESGLRAARRMLRAGKIVAVKGIGGYHLACDATG
Mvan_2407|M.vanbaalenii_PYR-1 TLRYRDGDG---RDTDGEPGLLAARRLLRDGGVLAVKGVGGYHLACDASD
MSMEG_2711|M.smegmatis_MC2_155 TLRLLTTEG---EHATGEHALQRARQLLATGGIVAVKGIGGYHLACDAAN
MMAR_1862|M.marinum_M SLWFRSATE---HVAGADAALAATQHALTAAKVVAIKGIGGYHLACAVDD
TH_1524|M.thermoresistible__bu RLGFRRGDQPVPDTHHTDAAISAAQGALAEGAVVAVKGIGGYHLACRADD
* : .: :: * . ::*:**:******* . .
Mflv_3979|M.gilvum_PYR-GCK PRAVTTLRARKRRGDKPFAVMVPDLDAARRVAEVDPASAALLTGPARPIV
Mvan_2407|M.vanbaalenii_PYR-1 RRAVAALRARKRRGDKPFAVMVPDIDAARAIADVDPASAALLRGPARPIV
MSMEG_2711|M.smegmatis_MC2_155 RVSVAELRHRKRRGDKPFAVMVADLATARAVAEVGDVAARLLCGPQRPIV
MMAR_1862|M.marinum_M DAVVGVLRSCKSRGAKPFAILVRDLDVARRYAFIDDAEAAVLSGPARPIV
TH_1524|M.thermoresistible__bu EDVVRALRSRKHRX------------------------GXXXQRPVGRIG
* ** * * . * *
Mflv_3979|M.gilvum_PYR-GCK LMPRRAGAAVADAVAPHNPDLGVVLAYAPLHTLLFG--FGGDEPAPQTLV
Mvan_2407|M.vanbaalenii_PYR-1 LMQRRAGAAVDAAVAPHNPDLGVLLTYTPLHALLLG--LDGDGPGPQVLV
MSMEG_2711|M.smegmatis_MC2_155 LIPRRSETLVCPEVSPHNPDLGVMLAYSPLHALLFG--LPGDPPGPAALV
MMAR_1862|M.marinum_M LLRRRPDAPVADAVASGSPLLGLMLPYSPIHHLLLAPVPGADAAAPEALV
TH_1524|M.thermoresistible__bu LGRGR---------------LGGRLGFP----------------------
* * ** * :.
Mflv_3979|M.gilvum_PYR-GCK MTSGNVAGEPICFTDDDAWQRLRPLADGWLYHDRAILVPCDDSVMR----
Mvan_2407|M.vanbaalenii_PYR-1 MTSGNLGGEPICFTEDAAFERLSCLADGWLWHDRAILVPCDDSVVR----
MSMEG_2711|M.smegmatis_MC2_155 MTSANLSGEPICFADDDALQRLSGLADAWLTHDRAILVPCDDSVVRVVDD
MMAR_1862|M.marinum_M LTSANRSDEPICFTESDAAERLSMLCDAVLDHDRPIHVPCDDSVVRVVED
TH_1524|M.thermoresistible__bu -------------------ARLRRRVPGR---------------------
** .
Mflv_3979|M.gilvum_PYR-GCK ----ADTAIRRSRGYAPLPVAL---PVALAPTLAVGADIKNTMAVADGRY
Mvan_2407|M.vanbaalenii_PYR-1 ----ADMPVRRSRGYAPLPIAL---PVAVSPTLAVGADLKNTMAVADGRY
MSMEG_2711|M.smegmatis_MC2_155 D-EVSEMAIRRSRGYAPLPVAL---PVPVVPTLAVGADLKNTVAVGDHEY
MMAR_1862|M.marinum_M AGLARELPIRRSRGYAPLPVDLGHIAVESPPVLAVGGELKNTFCLTDGTR
TH_1524|M.thermoresistible__bu ---------RRASGQGDQ----------------QGGDEQ----------
**: * . *.: :
Mflv_3979|M.gilvum_PYR-GCK AWVSQHIGDMDDAATLSAFDSTRRHLEQLTRVDPELLVADAHPAYRSTAW
Mvan_2407|M.vanbaalenii_PYR-1 AWLSQHIGDMDDLATLSVFDAAQQHLRRLTAVEPEVLVADAHPLYRSTAW
MSMEG_2711|M.smegmatis_MC2_155 AWLSGYIGDMDDLAALSAFDRAVTHLQALTGTTPRMLAADAHPGYRSTAW
MMAR_1862|M.marinum_M AYLSGHIGDMATWETLRAFERAVGQLSEIRG-HPVRLAADLHPGYHTRNW
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK AHRNAAGRPVRTVAHHHAHIAAVMAEHGLDGDEPVLGFAFDGTGYGPDGA
Mvan_2407|M.vanbaalenii_PYR-1 AHRNAAGRPVRSVQHHHAHIAAVMAEHGMDGSAPVLGFAFDGTGYGPDGA
MSMEG_2711|M.smegmatis_MC2_155 AHRNAGGRPVRSVQHHHAHIAAVMAEHGLDGSARVLGIAFDGTGFGSDGA
MMAR_1862|M.marinum_M AERHADDRPLDLIQHHHAHVVSLLAEHGR-INEPVVGVSFDGTGYGCDET
TH_1524|M.thermoresistible__bu --RETAGKTLR---------------------------------FG-DCR
*.: .:.: :* *
Mflv_3979|M.gilvum_PYR-GCK VWGGEVLLADYKG--YQRLARLRYVPLAGGDVSVKRPYRMALAHLWAAGL
Mvan_2407|M.vanbaalenii_PYR-1 VWGGEVLLADYKG--FQRLARLRYVPLAGGDVSVLRPYRMALTHLWAAGL
MSMEG_2711|M.smegmatis_MC2_155 VWGGEVLLADYKG--FERIAHLAYVPLAGGDVSVRRPYRMALSHLWAAGI
MMAR_1862|M.marinum_M IWGGEILVLGPQSHRFTRAGHLLAVPLPGGDAAVRNPWRMALSQLWTAHI
TH_1524|M.thermoresistible__bu AWRGRVDVLAGQG-----------IPP---DDRVNR--------------
* *.: : :. :* * * .
Mflv_3979|M.gilvum_PYR-GCK PWDRDLAPVRSCPAEELSVLRHQLETGLGCVPTSSMGRLFDAVSALAGVR
Mvan_2407|M.vanbaalenii_PYR-1 PWTPDLAPVRACPAAEQRVLRHQLETGLGCAPTSSMGRLFDAVSALAGVR
MSMEG_2711|M.smegmatis_MC2_155 PWDADLPPVRACPEGERRALCGQLNTGTGCVPTSSMGRLFDAVSALIGLR
MMAR_1862|M.marinum_M EWSPDLAPVAAAGVDELRVTRSQLASGAGCVPCSSMGRLFDAVASLLGVR
TH_1524|M.thermoresistible__bu ---------------------------------SRPGRLHPHVQ------
* ***. *
Mflv_3979|M.gilvum_PYR-GCK QVVGYEAQAAIELEGLSRHENCGDTRYRFGIGTGSSP-VDLDPAPVLAAV
Mvan_2407|M.vanbaalenii_PYR-1 QVVDYEAQAAIELEGLARDVGCNADGYRFTVDREPPT-AEIDPAPVLAAV
MSMEG_2711|M.smegmatis_MC2_155 QTVDYEAQAAIELEGQARHTPTGATAYAFAMHINRRP-VTFDAAPVLAAV
MMAR_1862|M.marinum_M HRIDYEGQAAIELEALAESALAECNGPRPSLPLTVRPDGVIDPTTMVQTL
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK VADAGRGIAPGVIGARFHRAVAALIADLASMSPGYR--VALSGGVFQNRL
Mvan_2407|M.vanbaalenii_PYR-1 VGDVGSGVGSGVVGARFHHAVARLILDLAVEHRGYP--VALSGGVFQNAL
MSMEG_2711|M.smegmatis_MC2_155 IADLRTHVPPAVISARFHQAVADLVVDLARLAAGGP--VALTGGVFQNAL
MMAR_1862|M.marinum_M VSALRAGTPPPVLAASFHQAVARAVAEVVAQVAGQVRLVGLTGGVFQNVL
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK LLQLAQDMLRANGFDVLTHRHVPPNDGGIALGQLMIGNAV----------
Mvan_2407|M.vanbaalenii_PYR-1 LLRTAQTLLVDNGFEVITHRHVPPNDGGIALGQLIVGNTA----------
MSMEG_2711|M.smegmatis_MC2_155 LLRLTLAGLRDSGIHALTACRVPPNDGGLALGQLLVGNAG----------
MMAR_1862|M.marinum_M LLRACRERLQRKGFEVLTHHTVPPNDGGLALGQAVVSLLIGLDEDWKRTD
TH_1524|M.thermoresistible__bu --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK -
Mvan_2407|M.vanbaalenii_PYR-1 -
MSMEG_2711|M.smegmatis_MC2_155 -
MMAR_1862|M.marinum_M R
TH_1524|M.thermoresistible__bu -