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VTARRRVHAGVRGVVQGVGFRPFVYTQATLLGLSGWVRNDSSGAIIEVEGGNDALERFLDVLRHHPPPLA VIDSIDVRYIAVTGGTGFTIVDTSRTDGGRTLASPDVAMCAECAAEQRDPRNRRYRHAFVNCTNCGPRFT LIASLPYDRASTTMAEFEMCADCAREYHDPADRRFHAQPICCPGCGPTLRYRDRAGRELAGESGLRAARR MLRAGKIVAVKGIGGYHLACDATGPRAVTTLRARKRRGDKPFAVMVPDLDAARRVAEVDPASAALLTGPA RPIVLMPRRAGAAVADAVAPHNPDLGVVLAYAPLHTLLFGFGGDEPAPQTLVMTSGNVAGEPICFTDDDA WQRLRPLADGWLYHDRAILVPCDDSVMRADTAIRRSRGYAPLPVALPVALAPTLAVGADIKNTMAVADGR YAWVSQHIGDMDDAATLSAFDSTRRHLEQLTRVDPELLVADAHPAYRSTAWAHRNAAGRPVRTVAHHHAH IAAVMAEHGLDGDEPVLGFAFDGTGYGPDGAVWGGEVLLADYKGYQRLARLRYVPLAGGDVSVKRPYRMA LAHLWAAGLPWDRDLAPVRSCPAEELSVLRHQLETGLGCVPTSSMGRLFDAVSALAGVRQVVGYEAQAAI ELEGLSRHENCGDTRYRFGIGTGSSPVDLDPAPVLAAVVADAGRGIAPGVIGARFHRAVAALIADLASMS PGYRVALSGGVFQNRLLLQLAQDMLRANGFDVLTHRHVPPNDGGIALGQLMIGNAV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3979 | - | - | 100% (756) | (NiFe) hydrogenase maturation protein HypF |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1444 | - | 9e-06 | 30.32% (155) | hypothetical protein MAB_1444 |
| M. marinum M | MMAR_1862 | hypF | 0.0 | 50.26% (770) | hydrogenase maturation factor, HypF |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_2711 | hypF | 0.0 | 69.03% (762) | [NiFe] hydrogenase maturation protein HypF [Mycobacterium |
| M. thermoresistible (build 8) | TH_1524 | hypF | 4e-41 | 57.66% (137) | - |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_2407 | - | 0.0 | 77.59% (754) | (NiFe) hydrogenase maturation protein HypF |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3979|M.gilvum_PYR-GCK ------------MTARRRVHAGVRGVVQGVGFRPFVYTQATLLGLSGWVR
Mvan_2407|M.vanbaalenii_PYR-1 ------------MTGRRRVRIDVRGVVQGVGFRPFVYTRATALGLSGSVR
MSMEG_2711|M.smegmatis_MC2_155 ------------MTARLRLRIDVHGVVQGVGFRPFVYTTAAAMGLTGHVR
MMAR_1862|M.marinum_M MAGLPLLRPAMVRCAETRQRFTVTGVVQGVGFRPFVHQLASELGLSGFVG
TH_1524|M.thermoresistible__bu --------------------------------------------------
MAB_1444|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK NDSSGAIIEVEGGNDALERFLDVLRHHPPPLAVIDSIDVRYIAVTGGTG-
Mvan_2407|M.vanbaalenii_PYR-1 NDSTGAIVEIEGAADDIDRFLARLHDHPPPLAVVESVDVRSVPLSGGTG-
MSMEG_2711|M.smegmatis_MC2_155 NDSSGAIIEIEGDEGDLERFLQRLHGGPPPLAVIESVEVRRITTVGGTG-
MMAR_1862|M.marinum_M NDSAAVFIEVQGGRAGLDEFARRLRADAPPLAGISSVSATELALQAGAAG
TH_1524|M.thermoresistible__bu --------------------------------------------------
MAB_1444|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK FTIVDTSRTDGGRTLASPDVAMCAECAAEQRDPRNRRYRHAFVNCTNCGP
Mvan_2407|M.vanbaalenii_PYR-1 FAIADTSRTDGGRTLASPDVAMCADCAAELRDPRNRRFRHPFINCTNCGP
MSMEG_2711|M.smegmatis_MC2_155 FRITDTSRADGGRTLVSPDVAMCRDCAAEQRDPANRRHRHAFINCTNCGP
MMAR_1862|M.marinum_M FRIVASQGATGATTPIPPDIAVCDDCVRELFDPRDRRFRHPFVTCTNCGP
TH_1524|M.thermoresistible__bu --------------------------VAELFDPADRRYRHPFITCTDCGP
MAB_1444|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK RFTLIASLPYDRASTTMAEFEMCADCAREYHDPADRRFHAQPICCPGCGP
Mvan_2407|M.vanbaalenii_PYR-1 RFTIIAALPYDRSSTTMADFPMCADCAGEYTDPTDRRFHAQPICCPGCGP
MSMEG_2711|M.smegmatis_MC2_155 RFTIIASLPYDRASTTMAGFPMCTECAREYRDPDDRRFHAQPVCCPNCGP
MMAR_1862|M.marinum_M RLTVIRTLPYDRPGTTMSAFPMCERCAAEYHDPGDRRFHAQPIACPNCGP
TH_1524|M.thermoresistible__bu RFTIIKALPYDRPATTMADFPMCDRCAEEYHDPTDRRFHAQPISCPDCGP
MAB_1444|M.abscessus_ATCC_1997 ----------------MTVVYDCQDAATR---------------------
*: . * .* .
Mflv_3979|M.gilvum_PYR-GCK TLRYRDRAGRELA---GESGLRAARRMLRAGKIVAVKGIGGYHLACDATG
Mvan_2407|M.vanbaalenii_PYR-1 TLRYRDGDGRDTD---GEPGLLAARRLLRDGGVLAVKGVGGYHLACDASD
MSMEG_2711|M.smegmatis_MC2_155 TLRLLTTEGEHAT---GEHALQRARQLLATGGIVAVKGIGGYHLACDAAN
MMAR_1862|M.marinum_M SLWFRSATEHVAG---ADAALAATQHALTAAKVVAIKGIGGYHLACAVDD
TH_1524|M.thermoresistible__bu RLGFRRGDQPVPDTHHTDAAISAAQGALAEGAVVAVKGIGGYHLACRADD
MAB_1444|M.abscessus_ATCC_1997 -----------------QSGIDAAVSALKAGELVVMPTDTVYGLGCDAFD
: .: : * . ::.: * *.* . .
Mflv_3979|M.gilvum_PYR-GCK PRAVTTLRARKRRG-DKPFAVMVPDLDAARRVAEVDPASAALLTGPARPI
Mvan_2407|M.vanbaalenii_PYR-1 RRAVAALRARKRRG-DKPFAVMVPDIDAARAIADVDPASAALLRGPARPI
MSMEG_2711|M.smegmatis_MC2_155 RVSVAELRHRKRRG-DKPFAVMVADLATARAVAEVGDVAARLLCGPQRPI
MMAR_1862|M.marinum_M DAVVGVLRSCKSRG-AKPFAILVRDLDVARRYAFIDDAEAAVLSGPARPI
TH_1524|M.thermoresistible__bu EDVVRALRSRKHRX-GXXXQRPVGRIGLGR------GRLGGRLGFPAR--
MAB_1444|M.abscessus_ATCC_1997 SGAVTALLAAKGRGRDMPVGVLVGSWHTIDGLVFAVPAAARELIEAFWP-
* * * * * . * .
Mflv_3979|M.gilvum_PYR-GCK VLMPRRAGAAVADAVAPHNPDLGVVLAYAPLHTLLFG--FGGDEPAPQTL
Mvan_2407|M.vanbaalenii_PYR-1 VLMQRRAGAAVDAAVAPHNPDLGVLLTYTPLHALLLG--LDGDGPGPQVL
MSMEG_2711|M.smegmatis_MC2_155 VLIPRRSETLVCPEVSPHNPDLGVMLAYSPLHALLFG--LPGDPPGPAAL
MMAR_1862|M.marinum_M VLLRRRPDAPVADAVASGSPLLGLMLPYSPIHHLLLAPVPGADAAAPEAL
TH_1524|M.thermoresistible__bu --LRRR--------------------------------VPGRRRAS----
MAB_1444|M.abscessus_ATCC_1997 -------------------GPLSIIVRHAPSLSWDLG-----DAQG----
.
Mflv_3979|M.gilvum_PYR-GCK VMTSGNVAGEPICFTDDDAWQRLRPLADGWLYHDRAILVPCDDSVMR---
Mvan_2407|M.vanbaalenii_PYR-1 VMTSGNLGGEPICFTEDAAFERLSCLADGWLWHDRAILVPCDDSVVR---
MSMEG_2711|M.smegmatis_MC2_155 VMTSANLSGEPICFADDDALQRLSGLADAWLTHDRAILVPCDDSVVRVVD
MMAR_1862|M.marinum_M VLTSANRSDEPICFTESDAAERLSMLCDAVLDHDRPIHVPCDDSVVRVVE
TH_1524|M.thermoresistible__bu -----GQGDQ----------------------------------------
MAB_1444|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK -----ADTAIRRSRGYAPLPVALP---VALAPTLAVGADIKNTMAVADGR
Mvan_2407|M.vanbaalenii_PYR-1 -----ADMPVRRSRGYAPLPIALP---VAVSPTLAVGADLKNTMAVADGR
MSMEG_2711|M.smegmatis_MC2_155 DDEV-SEMAIRRSRGYAPLPVALP---VPVVPTLAVGADLKNTVAVGDHE
MMAR_1862|M.marinum_M DAGLARELPIRRSRGYAPLPVDLGHIAVESPPVLAVGGELKNTFCLTDGT
TH_1524|M.thermoresistible__bu -----------------------------------QGGDEQ---------
MAB_1444|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK YAWVSQHIGDMDDAATLSAFDSTRRHLEQLTRVDPELLVADAHPAYRSTA
Mvan_2407|M.vanbaalenii_PYR-1 YAWLSQHIGDMDDLATLSVFDAAQQHLRRLTAVEPEVLVADAHPLYRSTA
MSMEG_2711|M.smegmatis_MC2_155 YAWLSGYIGDMDDLAALSAFDRAVTHLQALTGTTPRMLAADAHPGYRSTA
MMAR_1862|M.marinum_M RAYLSGHIGDMATWETLRAFERAVGQLSEIRG-HPVRLAADLHPGYHTRN
TH_1524|M.thermoresistible__bu ---------------------------RETAG-KTLRFG-------DCRA
MAB_1444|M.abscessus_ATCC_1997 ---------------------------SVMLRMPMHPVAIELLRAVGPMA
.
Mflv_3979|M.gilvum_PYR-GCK WAHRNAAGRPVRTVAHHHAHIAAVMAEHGLDGDEPVLGFAFDGTGYGPDG
Mvan_2407|M.vanbaalenii_PYR-1 WAHRNAAGRPVRSVQHHHAHIAAVMAEHGMDGSAPVLGFAFDGTGYGPDG
MSMEG_2711|M.smegmatis_MC2_155 WAHRNAGGRPVRSVQHHHAHIAAVMAEHGLDGSARVLGIAFDGTGFGSDG
MMAR_1862|M.marinum_M WAERHADDRPLDLIQHHHAHVVSLLAEHGRI-NEPVVGVSFDGTGYGCDE
TH_1524|M.thermoresistible__bu WRGR-----------------VDVLAGQG---------------------
MAB_1444|M.abscessus_ATCC_1997 VSSANVSGRP-----------AALTAAEAR--------------------
. : * ..
Mflv_3979|M.gilvum_PYR-GCK AVWGGEVLLADYKG--YQRLARLRYVPLAGGDVSVKRPYRMALAHLWAAG
Mvan_2407|M.vanbaalenii_PYR-1 AVWGGEVLLADYKG--FQRLARLRYVPLAGGDVSVLRPYRMALTHLWAAG
MSMEG_2711|M.smegmatis_MC2_155 AVWGGEVLLADYKG--FERIAHLAYVPLAGGDVSVRRPYRMALSHLWAAG
MMAR_1862|M.marinum_M TIWGGEILVLGPQSHRFTRAGHLLAVPLPGGDAAVRNPWRMALSQLWTAH
TH_1524|M.thermoresistible__bu ---------------------------IPPDD------------------
MAB_1444|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK LPWDRDLAPVRSCPAEELSVLRHQLETGLGCVPTSSMGRLFDAVSALAGV
Mvan_2407|M.vanbaalenii_PYR-1 LPWTPDLAPVRACPAAEQRVLRHQLETGLGCAPTSSMGRLFDAVSALAGV
MSMEG_2711|M.smegmatis_MC2_155 IPWDADLPPVRACPEGERRALCGQLNTGTGCVPTSSMGRLFDAVSALIGL
MMAR_1862|M.marinum_M IEWSPDLAPVAAAGVDELRVTRSQLASGAGCVPCSSMGRLFDAVASLLGV
TH_1524|M.thermoresistible__bu ------------------RVNR------------SRPGRLHPHVQ-----
MAB_1444|M.abscessus_ATCC_1997 -------------------------------------GQLDDKVAVYLDG
*:* *
Mflv_3979|M.gilvum_PYR-GCK RQVVGYEAQAAIELEGLSRHENCGDTRYRFGIGTGSSP-VDLDPAPVLAA
Mvan_2407|M.vanbaalenii_PYR-1 RQVVDYEAQAAIELEGLARDVGCNADGYRFTVDREPPT-AEIDPAPVLAA
MSMEG_2711|M.smegmatis_MC2_155 RQTVDYEAQAAIELEGQARHTPTGATAYAFAMHINRRP-VTFDAAPVLAA
MMAR_1862|M.marinum_M RHRIDYEGQAAIELEALAESALAECNGPRPSLPLTVRPDGVIDPTTMVQT
TH_1524|M.thermoresistible__bu --------------------------------------------------
MAB_1444|M.abscessus_ATCC_1997 GQAELGAASTIVDLTGPAP--------------------VIVREGPISRE
Mflv_3979|M.gilvum_PYR-GCK VVADAGRGIAPGVIGARFHRAVAALIADLASMSPGYR--VALSGGVFQNR
Mvan_2407|M.vanbaalenii_PYR-1 VVGDVGSGVGSGVVGARFHHAVARLILDLAVEHRGYP--VALSGGVFQNA
MSMEG_2711|M.smegmatis_MC2_155 VIADLRTHVPPAVISARFHQAVADLVVDLARLAAGGP--VALTGGVFQNA
MMAR_1862|M.marinum_M LVSALRAGTPPPVLAASFHQAVARAVAEVVAQVAGQVRLVGLTGGVFQNV
TH_1524|M.thermoresistible__bu --------------------------------------------------
MAB_1444|M.abscessus_ATCC_1997 QIVEVIGGQVGPVESGESGEPTES--------------------------
Mflv_3979|M.gilvum_PYR-GCK LLLQLAQDMLRANGFDVLTHRHVPPNDGGIALGQLMIGNAV---------
Mvan_2407|M.vanbaalenii_PYR-1 LLLRTAQTLLVDNGFEVITHRHVPPNDGGIALGQLIVGNTA---------
MSMEG_2711|M.smegmatis_MC2_155 LLLRLTLAGLRDSGIHALTACRVPPNDGGLALGQLLVGNAG---------
MMAR_1862|M.marinum_M LLLRACRERLQRKGFEVLTHHTVPPNDGGLALGQAVVSLLIGLDEDWKRT
TH_1524|M.thermoresistible__bu --------------------------------------------------
MAB_1444|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_3979|M.gilvum_PYR-GCK --
Mvan_2407|M.vanbaalenii_PYR-1 --
MSMEG_2711|M.smegmatis_MC2_155 --
MMAR_1862|M.marinum_M DR
TH_1524|M.thermoresistible__bu --
MAB_1444|M.abscessus_ATCC_1997 --