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VDDPLVNDDARALIADLTVRRQTVATAESLTAGLLAATLAGVPGASTVLRGGLVTYTVETKAELAGVAPE LLAEVGPVAEPTARALAVGAMQRCGATWGVGLTGVAGPEPHGGHRVGTVFLGLAGPVDTDVVRLQLAGGR WDIRLAAVHAAVHRLRLLVERQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2396 | - | - | 100% (162) | CinA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2999 | - | 3e-22 | 42.50% (160) | competence damage-inducible protein A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1936 | cinA | 1e-22 | 45.27% (148) | competence damage-inducible protein A |
| M. gilvum PYR-GCK | Mflv_3280 | - | 2e-25 | 45.00% (160) | competence damage-inducible protein A |
| M. tuberculosis H37Rv | Rv1901 | cinA | 1e-22 | 45.27% (148) | competence damage-inducible protein A |
| M. leprae Br4923 | MLBr_02015 | cinA | 8e-23 | 44.87% (156) | competence damage-inducible protein A |
| M. abscessus ATCC 19977 | MAB_2443 | - | 7e-18 | 40.58% (138) | competence damage-inducible protein A |
| M. marinum M | MMAR_2796 | cinA | 3e-25 | 46.54% (159) | competence/damage-inducible protein CinA |
| M. avium 104 | MAV_2800 | - | 2e-24 | 45.24% (168) | competence damage-inducible protein A |
| M. smegmatis MC2 155 | MSMEG_2693 | - | 2e-65 | 75.31% (162) | competence-damaged protein |
| M. thermoresistible (build 8) | TH_0499 | cinA | 1e-22 | 41.40% (157) | PROBABLE CINA-LIKE PROTEIN CINA |
| M. ulcerans Agy99 | MUL_2956 | cinA | 2e-25 | 46.54% (159) | competence damage-inducible protein A |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1936|M.bovis_AF2122/97 ----MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITIC
Rv1901|M.tuberculosis_H37Rv ----MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITIC
MMAR_2796|M.marinum_M ----MAVSARAGIVVTGTEVLTGRVQDRNGPWIADQLLELGVELAHITIC
MUL_2956|M.ulcerans_Agy99 MRRLRPVSARAGIVVTGTEVLTGRVQDRNGPWIADQLLELGVELAHITIC
MAV_2800|M.avium_104 ----MPVSARAGIVVTGTEVLTGRVQDANGPWIADRLLELGVELAHITIC
MLBr_02015|M.leprae_Br4923 MRRLMVVSARAGIVVTGTEILTGRVRDRNGPWLADRLLELGVKLAHITIC
Mflv_3280|M.gilvum_PYR-GCK ------MSARAGIVVTGTEVLTGRVQDLNGPWLADRLLELGVELSHITLC
TH_0499|M.thermoresistible__bu ------VSTRAGIVVTGTEVLTGRIQDQNGPWLADRLLELGVELAHVTIC
MAB_2443|M.abscessus_ATCC_1997 -------MLRAGIVVTGTEVLTGRVADANGPWLAEHLRKVGVDVAHLCVC
Mvan_2396|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2693|M.smegmatis_MC2_155 --------------------------------------------------
Mb1936|M.bovis_AF2122/97 GDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVL
Rv1901|M.tuberculosis_H37Rv GDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVL
MMAR_2796|M.marinum_M GDRPADIEAQLRFMADQDLDLIITSGGLGPTADDMTVEVVARFCGRELIL
MUL_2956|M.ulcerans_Agy99 GDRPADIGAQLRFMADQDLDLIITSGGLGPTADDMTVEVVARFCGRELIL
MAV_2800|M.avium_104 GDRPHDIEAQLRFLADQGVDLIVTSGGLGPTADDMTVEVVARFCGRELVL
MLBr_02015|M.leprae_Br4923 GDCPADIEAQLRFMAEAGVDLIVTSGGLGPTADDMTVEVVARFCNREMVL
Mflv_3280|M.gilvum_PYR-GCK GDRPADIEAQLRFLADQGVDLIITSGGLGPTADDMTVEVVSRFCGRELEL
TH_0499|M.thermoresistible__bu GDRPADLEAQLRFHADTGVDLLITTGGLGPTADDLTVETVARFCGRELML
MAB_2443|M.abscessus_ATCC_1997 GDRREDLLAQLKFLTDQGVDLIVTSGGLGPTADDMTLPTVAEFAGTTLIF
Mvan_2396|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2693|M.smegmatis_MC2_155 --------------------------------------------------
Mb1936|M.bovis_AF2122/97 DDELENRIANILKKLMGRNPAIE----PANFDSIRAANRKQAMIPAGSQV
Rv1901|M.tuberculosis_H37Rv DDELENRIANILKKLMGRNPAIE----PANFDSIRAANRKQAMIPAGSQV
MMAR_2796|M.marinum_M DAELEDTIANILKRLMARNPGFD----PGNFDSVRAANQKQAMIPAGAQV
MUL_2956|M.ulcerans_Agy99 DTKLEDTIANILKRLMARNPGFD----PGNFDSVLAANQKQAMVPAGAQV
MAV_2800|M.avium_104 DAEVEEKIANILKKLMARNPAFQSALDPGTFESLRAANRKQAMVPAGAQV
MLBr_02015|M.leprae_Br4923 DVELENKIAAILNSLMTR---FN----PGDFEAVRAANRKQAMIPAGSQV
Mflv_3280|M.gilvum_PYR-GCK DPGLETRIGEIVTRLMARFPDVD----P---AAVIAANRKQAFVPDGAVI
TH_0499|M.thermoresistible__bu DAVVEEKIAAILRTMMGRIGPNETGAGMTDFEAVRAANRKQAMVPAGATV
MAB_2443|M.abscessus_ATCC_1997 DDVLETAIMDRLRPMANRWENVD-------WEALRVGIAKQALVPARGQI
Mvan_2396|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2693|M.smegmatis_MC2_155 --------------------------------------------------
Mb1936|M.bovis_AF2122/97 IDPVGTAPG-LVVPGRPAVMVLPGPPRELQPIWSKAIQTAPVQDAIAG-R
Rv1901|M.tuberculosis_H37Rv IDPVGTAPG-LVVPGRPAVMVLPGPPRELQPIWSKAIQTAPVQDAIAG-R
MMAR_2796|M.marinum_M INPVGTAPG-LVVPGKPAVMVLPGPPRELQPMWHSAIQMPGAQEAIAG-R
MUL_2956|M.ulcerans_Agy99 INPVGTAPG-LVVPGKPAVVVLPGPPRELQPMWHSAIQMPGAQEAIAG-R
MAV_2800|M.avium_104 LDPVGTAPG-VVVPGKPAVIVLPGPPRELQPMWHTAIQTPAAQQAIAG-R
MLBr_02015|M.leprae_Br4923 LDPIGTAPG-LVVPGKPTVMVLPGPPSELQPMWRRAVMTAATREAIAD-R
Mflv_3280|M.gilvum_PYR-GCK LDPVGTAPG-VVVPGTPTVVVLPGPPRELQPMWQAAVAADAVQTAIAD-R
TH_0499|M.thermoresistible__bu LDPVGTAPG-LVVAGTPTVVVLPGPPRELQPMWRRALTTAEVQRAIAG-R
MAB_2443|M.abscessus_ATCC_1997 LDPVGTAPGAIMSAGDVLIVVLPGPPHELQRMWQTAVNAAPFRALVGDDA
Mvan_2396|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2693|M.smegmatis_MC2_155 --------------------------------------------------
Mb1936|M.bovis_AF2122/97 TTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVT
Rv1901|M.tuberculosis_H37Rv TTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEMVT
MMAR_2796|M.marinum_M TTYRQETIRMFGLPESGLAETLRSAETTIPDFGALEITTCLRRGEIEMVT
MUL_2956|M.ulcerans_Agy99 TTYRQETIRMFGLPESGLAATLRSAETTIPDFGALEITTCLRRGEIEMVT
MAV_2800|M.avium_104 TVYRQEMLRMFGLPESGLAETLREAEAAVPGFGQLEITTCLRRGEIEMVT
MLBr_02015|M.leprae_Br4923 TIYRQQTLRMFGLSESGLAETLRDAQASIPGFDALEITTCLRRGEIEMVT
Mflv_3280|M.gilvum_PYR-GCK VSYRQDTVRMFGLPESGLAETLREAEGSVAGFDRLEITTCLRRGELEIVT
TH_0499|M.thermoresistible__bu THYRQDTVRMFGLPESRLAETLRDARERIPGFDALEITTCLRRGEVEMVT
MAB_2443|M.abscessus_ATCC_1997 AAIEETVLRLYGITEPDIAETLRLAENALGGLAALEITTCLRRSEVEVVT
Mvan_2396|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_2693|M.smegmatis_MC2_155 --------------------------------------------------
Mb1936|M.bovis_AF2122/97 RFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLT-GRRIATA
Rv1901|M.tuberculosis_H37Rv RFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLT-GRRIATA
MMAR_2796|M.marinum_M RYEPGAADTYAQVARLLRDRHGDQIYSEDGSQVDDLVARLLA-DRRIATA
MUL_2956|M.ulcerans_Agy99 RYELGAADTYAQVARLLRDRHGDQIYSEDGSQVDDLVARLLA-DRRIATA
MAV_2800|M.avium_104 RYEPTAATAYAQLTKLLRDKHGDQLYSEDGSRVDDLVARLLA-GRRIATA
MLBr_02015|M.leprae_Br4923 RYEPDVVNVYVELTQLLRDRHGHQLYSEDGARVDDLIAHLLA-GRRIATA
Mflv_3280|M.gilvum_PYR-GCK RYEPRDADAYDGLLNMLRDKHSRELFSEDGALVDDQVAALLA-GRTIATA
TH_0499|M.thermoresistible__bu RYEPAAAPSYAELVELLIERHPREVFSTDGALVDEQVAELLR-GRRLAVA
MAB_2443|M.abscessus_ATCC_1997 RFDSSARSVWQGLYEFIRARHGVALFSSDGSTVDEVVAALLH-GRRLAVA
Mvan_2396|M.vanbaalenii_PYR-1 --------------------MDDPLVNDDAR---ALIADLTVRRQTVATA
MSMEG_2693|M.smegmatis_MC2_155 --------------------MDDPLTTDDAR---ALVADLTVYGQSVATA
: . *. :* * : :*.*
Mb1936|M.bovis_AF2122/97 ESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGA
Rv1901|M.tuberculosis_H37Rv ESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGA
MMAR_2796|M.marinum_M ESCTAGLLAARLTDRPGSSGYVMGGVVSYSNEAKAELLGVDPALIEMHGA
MUL_2956|M.ulcerans_Agy99 ESCTAGLLAARLTDRPGSSAYVMGGVVSYSNEAKAELLGVDPALIEMHGA
MAV_2800|M.avium_104 ESCTAGLLAARLTDRPGSSDYVAGGVVAYSNEAKAELLGVDPALIETHGA
MLBr_02015|M.leprae_Br4923 ESCTAGLLAARLTERPGSSDYVAGALVAYSNEAKVTLLGVDPALIAEHGE
Mflv_3280|M.gilvum_PYR-GCK ESCTAGLLAARLTDRAGSSAYVAGGVVSYSNDAKTDLLGVDAELIAAHGA
TH_0499|M.thermoresistible__bu ESCTAGLLAARLTERPGASAYLAGGVVAYANDAKTDLLEVAPALLESFGA
MAB_2443|M.abscessus_ATCC_1997 ESCTAGLLGARIADVPGSSAYFLGGVISYANDVKVGQLCVDPDLLASHGA
Mvan_2396|M.vanbaalenii_PYR-1 ESLTAGLLAATLAGVPGASTVLRGGLVTYTVETKAELAGVAPELLAEVGP
MSMEG_2693|M.smegmatis_MC2_155 ESLTAGLLAATLAGVPGASAVLHGGLITYTEDTKIWLAGVAPQVLDAVGP
** *****.* :: .*:* . *.:::*: :.* * . :: *
Mb1936|M.bovis_AF2122/97 VSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLD
Rv1901|M.tuberculosis_H37Rv VSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLD
MMAR_2796|M.marinum_M VSEPVAQAMAAGALQRFGADTAVAITGIAGPGGGTEQKPVGTVCFCVLVG
MUL_2956|M.ulcerans_Agy99 VSEPVAQAMAAGAFQRFGADTAVAITGIAGPGGGTEQKPVGTVCFCVLVG
MAV_2800|M.avium_104 VSEPVAQAMAAGARQRFAADTAVAITGIAGPGGGTEEKPVGTVCFSVQVG
MLBr_02015|M.leprae_Br4923 VSEPVVEAMAAGALQRFDVDTAAAISGIAGPGGGTAEKPIGTVCFTVMLA
Mflv_3280|M.gilvum_PYR-GCK VSEPVAEAMAAGALQRFGADTAVAITGIAGPGGGTPAKPVGTVCFSVALA
TH_0499|M.thermoresistible__bu VSEPVAEAMAAGVLRRFGADTAVAVTGIAGPGGGSPDKPVGTVCFAVLLD
MAB_2443|M.abscessus_ATCC_1997 VSPEVAEAMADGALKALGADIAVSTTGVAGPGGGSPDKPVGTVCFCAKTA
Mvan_2396|M.vanbaalenii_PYR-1 VAEPTARALAVGAMQRCGATWGVGLTGVAGPEP-HGGHRVGTVFLGLAGP
MSMEG_2693|M.smegmatis_MC2_155 VSAPTARALAVGARQRCAATWGVSLTGVAGPEA-HGGHPPGTVFLGIAGP
*: ...*:* *. : . ... :*:*** : *** :
Mb1936|M.bovis_AF2122/97 ----DGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP-
Rv1901|M.tuberculosis_H37Rv ----DGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP-
MMAR_2796|M.marinum_M ----DGRNVTRTLRLPGNRSDIRERSTTVAMHLLRRALSE------
MUL_2956|M.ulcerans_Agy99 ----DGRNVTRTLRLPGNRSDIRERSTTVAMHLLRRALSE------
MAV_2800|M.avium_104 PPGATARSDTRTLRLPGNRLDIRERSTTVAMHLLRRLLTDA-----
MLBr_02015|M.leprae_Br4923 D---GGPTLTRTLRLPGNRSDIRERSTTVAMHLLRHALSDTDSVP-
Mflv_3280|M.gilvum_PYR-GCK ----DGTFLTRTSQLPGNRSDVRERSTTVAMHLLRRALSGGG----
TH_0499|M.thermoresistible__bu ----DGRKAARTVRLPGGRADVRERSTTVALHLLRRALLEAAPAGA
MAB_2443|M.abscessus_ATCC_1997 ----AGEKAELRVVIPGNRNQIRERATTVALHLLRRLLS-------
Mvan_2396|M.vanbaalenii_PYR-1 -----VDTDVVRLQLAGGRWDIRLAAVHAAVHRLRLLVERQ-----
MSMEG_2693|M.smegmatis_MC2_155 -----IDTHVAELSLSGSRWEIRVAAVNAAISRLRALVEQQ-----
:.*.* ::* :. .*: ** :