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MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITICGDRPADIEAQLRFMAEQGVDLIVT SGGLGPTADDMTVEVVARYCGRELVLDDELENRIANILKKLMGRNPAIEPANFDSIRAANRKQAMIPAGS QVIDPVGTAPGLVVPGRPAVMVLPGPPRELQPIWSKAIQTAPVQDAIAGRTTYRQETIRIFGLPESSLAD TLRDAEAAIPGFDLVEITTCLRRGEIEMVTRFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKL LTGRRIATAESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHGAVSEPVAQAMAA GALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLLDDGRTTTRTVRLPGNRSDIRERSTTVAMHLLR RTLSGIPGSP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1901 | cinA | - | 100% (430) | competence damage-inducible protein A |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1936 | cinA | 0.0 | 100.00% (430) | competence damage-inducible protein A |
| M. gilvum PYR-GCK | Mflv_3280 | - | 1e-178 | 73.05% (423) | competence damage-inducible protein A |
| M. leprae Br4923 | MLBr_02015 | cinA | 0.0 | 77.03% (431) | competence damage-inducible protein A |
| M. abscessus ATCC 19977 | MAB_2443 | - | 1e-126 | 53.44% (421) | competence damage-inducible protein A |
| M. marinum M | MMAR_2796 | cinA | 0.0 | 83.02% (424) | competence/damage-inducible protein CinA |
| M. avium 104 | MAV_2800 | - | 0.0 | 80.00% (430) | competence damage-inducible protein A |
| M. smegmatis MC2 155 | MSMEG_3512 | - | 1e-172 | 71.43% (427) | competence damage-inducible protein A |
| M. thermoresistible (build 8) | TH_0499 | cinA | 1e-177 | 71.76% (425) | PROBABLE CINA-LIKE PROTEIN CINA |
| M. ulcerans Agy99 | MUL_2956 | cinA | 0.0 | 81.28% (422) | competence damage-inducible protein A |
| M. vanbaalenii PYR-1 | Mvan_2999 | - | 1e-178 | 73.29% (423) | competence damage-inducible protein A |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3280|M.gilvum_PYR-GCK ------MSARAGIVVTGTEVLTGRVQDLNGPWLADRLLELGVELSHITLC
Mvan_2999|M.vanbaalenii_PYR-1 ------MSARAGIVVTGTEVLTGRVQDQNGPWLADRLLELGVELGHITLC
Rv1901|M.tuberculosis_H37Rv ----MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITIC
Mb1936|M.bovis_AF2122/97 ----MAVSARAGIVITGTEVLTGRVQDRNGPWIADRLLELGVELAHITIC
MMAR_2796|M.marinum_M ----MAVSARAGIVVTGTEVLTGRVQDRNGPWIADQLLELGVELAHITIC
MUL_2956|M.ulcerans_Agy99 MRRLRPVSARAGIVVTGTEVLTGRVQDRNGPWIADQLLELGVELAHITIC
MAV_2800|M.avium_104 ----MPVSARAGIVVTGTEVLTGRVQDANGPWIADRLLELGVELAHITIC
MLBr_02015|M.leprae_Br4923 MRRLMVVSARAGIVVTGTEILTGRVRDRNGPWLADRLLELGVKLAHITIC
MSMEG_3512|M.smegmatis_MC2_155 ---MHVVSARAGIVITGTEVLTGRIQDLNGPWLADQLLELGVELAHITIC
TH_0499|M.thermoresistible__bu ------VSTRAGIVVTGTEVLTGRIQDQNGPWLADRLLELGVELAHVTIC
MAB_2443|M.abscessus_ATCC_1997 -------MLRAGIVVTGTEVLTGRVADANGPWLAEHLRKVGVDVAHLCVC
*****:****:****: * ****:*::* ::**.:.*: :*
Mflv_3280|M.gilvum_PYR-GCK GDRPADIEAQLRFLADQGVDLIITSGGLGPTADDMTVEVVSRFCGRELEL
Mvan_2999|M.vanbaalenii_PYR-1 GDRPADIEAQLRFLAGQGVDLIITSGGLGPTADDMTVEIVSRFCGRELVL
Rv1901|M.tuberculosis_H37Rv GDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVL
Mb1936|M.bovis_AF2122/97 GDRPADIEAQLRFMAEQGVDLIVTSGGLGPTADDMTVEVVARYCGRELVL
MMAR_2796|M.marinum_M GDRPADIEAQLRFMADQDLDLIITSGGLGPTADDMTVEVVARFCGRELIL
MUL_2956|M.ulcerans_Agy99 GDRPADIGAQLRFMADQDLDLIITSGGLGPTADDMTVEVVARFCGRELIL
MAV_2800|M.avium_104 GDRPHDIEAQLRFLADQGVDLIVTSGGLGPTADDMTVEVVARFCGRELVL
MLBr_02015|M.leprae_Br4923 GDCPADIEAQLRFMAEAGVDLIVTSGGLGPTADDMTVEVVARFCNREMVL
MSMEG_3512|M.smegmatis_MC2_155 GDRPGDIAAQLKFLADEGVDLIITSGGLGPTADDLTVATVAEFCGRELVL
TH_0499|M.thermoresistible__bu GDRPADLEAQLRFHADTGVDLLITTGGLGPTADDLTVETVARFCGRELML
MAB_2443|M.abscessus_ATCC_1997 GDRREDLLAQLKFLTDQGVDLIVTSGGLGPTADDMTLPTVAEFAGTTLIF
** *: ***:* : .:**::*:*********:*: *:.:.. : :
Mflv_3280|M.gilvum_PYR-GCK DPGLETRIGEIVTRLMARFPDVD-------PAAVIAANRKQAFVPDGAVI
Mvan_2999|M.vanbaalenii_PYR-1 DAAVEARIGEIVKGMMARFPGVD-------ADAVLAANRKQALVPAGAVV
Rv1901|M.tuberculosis_H37Rv DDELENRIANILKKLMGRNPAIE----PANFDSIRAANRKQAMIPAGSQV
Mb1936|M.bovis_AF2122/97 DDELENRIANILKKLMGRNPAIE----PANFDSIRAANRKQAMIPAGSQV
MMAR_2796|M.marinum_M DAELEDTIANILKRLMARNPGFD----PGNFDSVRAANQKQAMIPAGAQV
MUL_2956|M.ulcerans_Agy99 DTKLEDTIANILKRLMARNPGFD----PGNFDSVLAANQKQAMVPAGAQV
MAV_2800|M.avium_104 DAEVEEKIANILKKLMARNPAFQSALDPGTFESLRAANRKQAMVPAGAQV
MLBr_02015|M.leprae_Br4923 DVELENKIAAILNSLMTR---FN----PGDFEAVRAANRKQAMIPAGSQV
MSMEG_3512|M.smegmatis_MC2_155 DEALEERIAAILRRLTAGRNLSE-----ENFEAVRTANRKQALIPQGAEI
TH_0499|M.thermoresistible__bu DAVVEEKIAAILRTMMGRIGPNETGAGMTDFEAVRAANRKQAMVPAGATV
MAB_2443|M.abscessus_ATCC_1997 DDVLETAIMDRLRPMANRWENVD-------WEALRVGIAKQALVPARGQI
* :* * : : : :: .. ***::* . :
Mflv_3280|M.gilvum_PYR-GCK LDPVGTAPGVVVPGTP---TVVVLPGPPRELQPMWQAAVAADAVQTAIAD
Mvan_2999|M.vanbaalenii_PYR-1 LDPVGTAPGVVVAGSP---TVVVLPGPPRELQPMWHAAVATDAVQTAIAG
Rv1901|M.tuberculosis_H37Rv IDPVGTAPGLVVPGRP---AVMVLPGPPRELQPIWSKAIQTAPVQDAIAG
Mb1936|M.bovis_AF2122/97 IDPVGTAPGLVVPGRP---AVMVLPGPPRELQPIWSKAIQTAPVQDAIAG
MMAR_2796|M.marinum_M INPVGTAPGLVVPGKP---AVMVLPGPPRELQPMWHSAIQMPGAQEAIAG
MUL_2956|M.ulcerans_Agy99 INPVGTAPGLVVPGKP---AVVVLPGPPRELQPMWHSAIQMPGAQEAIAG
MAV_2800|M.avium_104 LDPVGTAPGVVVPGKP---AVIVLPGPPRELQPMWHTAIQTPAAQQAIAG
MLBr_02015|M.leprae_Br4923 LDPIGTAPGLVVPGKP---TVMVLPGPPSELQPMWRRAVMTAATREAIAD
MSMEG_3512|M.smegmatis_MC2_155 LEPVGTAPGVVVPGSPGSPTVVVLPGPPRELQPMWLRAVDTEPVRRAIAG
TH_0499|M.thermoresistible__bu LDPVGTAPGLVVAGTP---TVVVLPGPPRELQPMWRRALTTAEVQRAIAG
MAB_2443|M.abscessus_ATCC_1997 LDPVGTAPGAIMSAGD--VLIVVLPGPPHELQRMWQTAVNAAPFRALVGD
::*:***** ::.. ::****** *** :* *: : :..
Mflv_3280|M.gilvum_PYR-GCK -RVSYRQDTVRMFGLPESGLAETLREAEGSVAGFDRLEITTCLRRGELEI
Mvan_2999|M.vanbaalenii_PYR-1 -RTRYQQQTIRMFGLPESGLADTLRDAEKTVADFDRLEITTCLRRGELEI
Rv1901|M.tuberculosis_H37Rv -RTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEM
Mb1936|M.bovis_AF2122/97 -RTTYRQETIRIFGLPESSLADTLRDAEAAIPGFDLVEITTCLRRGEIEM
MMAR_2796|M.marinum_M -RTTYRQETIRMFGLPESGLAETLRSAETTIPDFGALEITTCLRRGEIEM
MUL_2956|M.ulcerans_Agy99 -RTTYRQETIRMFGLPESGLAATLRSAETTIPDFGALEITTCLRRGEIEM
MAV_2800|M.avium_104 -RTVYRQEMLRMFGLPESGLAETLREAEAAVPGFGQLEITTCLRRGEIEM
MLBr_02015|M.leprae_Br4923 -RTIYRQQTLRMFGLSESGLAETLRDAQASIPGFDALEITTCLRRGEIEM
MSMEG_3512|M.smegmatis_MC2_155 -RTVYRQEMIRMFGLAESGLAETLRAAEQAISGFDRLEITTCLRRGELEI
TH_0499|M.thermoresistible__bu -RTHYRQDTVRMFGLPESRLAETLRDARERIPGFDALEITTCLRRGEVEM
MAB_2443|M.abscessus_ATCC_1997 DAAAIEETVLRLYGITEPDIAETLRLAENALGGLAALEITTCLRRSEVEV
. .: :*::*:.*. :* *** *. : .: :********.*:*:
Mflv_3280|M.gilvum_PYR-GCK VTRYEPRDADAYDGLLNMLRDKHSRELFSEDGALVDDQVAALLAGRTIAT
Mvan_2999|M.vanbaalenii_PYR-1 VTRFEPRDTATYAALEGLLRDRHAREIFSTDGALVDDQIAELLAGRSIAT
Rv1901|M.tuberculosis_H37Rv VTRFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIAT
Mb1936|M.bovis_AF2122/97 VTRFEPNAAQVYTQLARLLRDRHGHQVYSEDGASVDELVAKLLTGRRIAT
MMAR_2796|M.marinum_M VTRYEPGAADTYAQVARLLRDRHGDQIYSEDGSQVDDLVARLLADRRIAT
MUL_2956|M.ulcerans_Agy99 VTRYELGAADTYAQVARLLRDRHGDQIYSEDGSQVDDLVARLLADRRIAT
MAV_2800|M.avium_104 VTRYEPTAATAYAQLTKLLRDKHGDQLYSEDGSRVDDLVARLLAGRRIAT
MLBr_02015|M.leprae_Br4923 VTRYEPDVVNVYVELTQLLRDRHGHQLYSEDGARVDDLIAHLLAGRRIAT
MSMEG_3512|M.smegmatis_MC2_155 VTRYEPAAADAYGQLLDVLRDRHGDAVYSEDGSTVDQQVAALLAGRRIAT
TH_0499|M.thermoresistible__bu VTRYEPAAAPSYAELVELLIERHPREVFSTDGALVDEQVAELLRGRRLAV
MAB_2443|M.abscessus_ATCC_1997 VTRFDSSARSVWQGLYEFIRARHGVALFSSDGSTVDEVVAALLHGRRLAV
***:: : : .: :* ::* **: **: :* ** .* :*.
Mflv_3280|M.gilvum_PYR-GCK AESCTAGLLAARLTDRAGSSAYVAGGVVSYSNDAKTDLLGVDAELIAAHG
Mvan_2999|M.vanbaalenii_PYR-1 AESCTAGMLAARLTERAGSSAYVAGGVVAYSNAAKTELLGVDAGLIERHG
Rv1901|M.tuberculosis_H37Rv AESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHG
Mb1936|M.bovis_AF2122/97 AESCTAGLLAARLTDRPGSSKYVAGAVVAYSNEAKAQLLGVDPALIEAHG
MMAR_2796|M.marinum_M AESCTAGLLAARLTDRPGSSGYVMGGVVSYSNEAKAELLGVDPALIEMHG
MUL_2956|M.ulcerans_Agy99 AESCTAGLLAARLTDRPGSSAYVMGGVVSYSNEAKAELLGVDPALIEMHG
MAV_2800|M.avium_104 AESCTAGLLAARLTDRPGSSDYVAGGVVAYSNEAKAELLGVDPALIETHG
MLBr_02015|M.leprae_Br4923 AESCTAGLLAARLTERPGSSDYVAGALVAYSNEAKVTLLGVDPALIAEHG
MSMEG_3512|M.smegmatis_MC2_155 AESCTAGLLAARLTDQPGASEYMMGGIVAYANTPKAEMLNVDPVLIAEHG
TH_0499|M.thermoresistible__bu AESCTAGLLAARLTERPGASAYLAGGVVAYANDAKTDLLEVAPALLESFG
MAB_2443|M.abscessus_ATCC_1997 AESCTAGLLGARIADVPGSSAYFLGGVISYANDVKVGQLCVDPDLLASHG
*******:*.**::: .*:* *. *.:::*:* *. * * . *: .*
Mflv_3280|M.gilvum_PYR-GCK AVSEPVAEAMAAGALQRFGADTAVAITGIAGPGGGTPAKPVGTVCFSVAL
Mvan_2999|M.vanbaalenii_PYR-1 AVSEPVAEAMAAGALQRFGADTAVAITGIAGPGGGTPTKPVGTVCFSVAL
Rv1901|M.tuberculosis_H37Rv AVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLL
Mb1936|M.bovis_AF2122/97 AVSEPVAQAMAAGALQGFGADTATAITGIAGPSGGTPEKPVGTVCFTVLL
MMAR_2796|M.marinum_M AVSEPVAQAMAAGALQRFGADTAVAITGIAGPGGGTEQKPVGTVCFCVLV
MUL_2956|M.ulcerans_Agy99 AVSEPVAQAMAAGAFQRFGADTAVAITGIAGPGGGTEQKPVGTVCFCVLV
MAV_2800|M.avium_104 AVSEPVAQAMAAGARQRFAADTAVAITGIAGPGGGTEEKPVGTVCFSVQV
MLBr_02015|M.leprae_Br4923 EVSEPVVEAMAAGALQRFDVDTAAAISGIAGPGGGTAEKPIGTVCFTVML
MSMEG_3512|M.smegmatis_MC2_155 AVSEPVAEAMATGAMHHFEADTAVAITGIAGPGGGSTEKPVGTVCFAVRA
TH_0499|M.thermoresistible__bu AVSEPVAEAMAAGVLRRFGADTAVAVTGIAGPGGGSPDKPVGTVCFAVLL
MAB_2443|M.abscessus_ATCC_1997 AVSPEVAEAMADGALKALGADIAVSTTGVAGPGGGSPDKPVGTVCFCAKT
** *.:*** *. : : .* *.: :*:***.**: **:***** .
Mflv_3280|M.gilvum_PYR-GCK A----DGTFLTRTSQLPGNRSDVRERSTTVAMHLLRRALSGGG----
Mvan_2999|M.vanbaalenii_PYR-1 A----GGASVTRATRLPGNRSDIRERSTTVAMHLLRRALTGGG----
Rv1901|M.tuberculosis_H37Rv D----DGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP-
Mb1936|M.bovis_AF2122/97 D----DGRTTTRTVRLPGNRSDIRERSTTVAMHLLRRTLSGIPGSP-
MMAR_2796|M.marinum_M G----DGRNVTRTLRLPGNRSDIRERSTTVAMHLLRRALSE------
MUL_2956|M.ulcerans_Agy99 G----DGRNVTRTLRLPGNRSDIRERSTTVAMHLLRRALSE------
MAV_2800|M.avium_104 GPPGATARSDTRTLRLPGNRLDIRERSTTVAMHLLRRLLTDA-----
MLBr_02015|M.leprae_Br4923 AD---GGPTLTRTLRLPGNRSDIRERSTTVAMHLLRHALSDTDSVP-
MSMEG_3512|M.smegmatis_MC2_155 E-----GASITRTLLLPGNRSDIRERSTTVAMHLLRRALRGESD---
TH_0499|M.thermoresistible__bu D----DGRKAARTVRLPGGRADVRERSTTVALHLLRRALLEAAPAGA
MAB_2443|M.abscessus_ATCC_1997 A----AGEKAELRVVIPGNRNQIRERATTVALHLLRRLLS-------
. :**.* ::***:****:****: *