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MRIFAAALTAAGATAGLLAVPAAGLLAAPAAGAQSACAELGGTVDAEQTCHVHAENSTYRLDYTFPVDYP DQQALAAYLTQTRDGFVNVSEMPGSWNLPYVLDGRGTGYRTGPDGAGTRSVVFEVYENVGGAHPQTWFKA FNWDVAKKAPITFDTLFRPDTKPLDVIFPIVQKDISRQLGVDAPISAADGLDPAKYQEFALTDDSLIFYF GQGEIMPGAGGALQATVPRSAVAAMLAEPAVTQG
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_2092 | - | - | 100% (244) | immunogenic protein MPB64/MPT64 precursor |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3062c | TB22.2 | 2e-67 | 56.82% (220) | hypothetical protein Mb3062c |
M. gilvum PYR-GCK | Mflv_4267 | - | 1e-104 | 76.37% (237) | immunogenic protein MPB64/MPT64 precursor |
M. tuberculosis H37Rv | Rv3036c | TB22.2 | 7e-68 | 57.27% (220) | hypothetical protein Rv3036c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1835c | - | 5e-35 | 31.87% (273) | immunogenic protein MPT64 precursor |
M. marinum M | MMAR_1665 | - | 1e-63 | 53.08% (211) | hypothetical protein MMAR_1665 |
M. avium 104 | MAV_3901 | - | 7e-57 | 47.71% (218) | immunogenic protein MPB64/MPT64 |
M. smegmatis MC2 155 | MSMEG_2331 | - | 9e-75 | 58.33% (228) | immunogenic protein MPB64/MPT64 |
M. thermoresistible (build 8) | TH_2187 | - | 6e-78 | 60.99% (223) | PROBABLE CONSERVED SECRETED PROTEIN TB22.2 |
M. ulcerans Agy99 | MUL_1902 | - | 2e-62 | 52.61% (211) | hypothetical protein MUL_1902 |
CLUSTAL 2.0.9 multiple sequence alignment Mb3062c|M.bovis_AF2122/97 MRYLIA-------TAVLVAVVLVG---WPAAGAPPSCAGLGGTVQAGQIC Rv3036c|M.tuberculosis_H37Rv MRYLIA-------TAVLVAVVLVG---WPAAGAPPSCAGLGGTVQAGQIC MMAR_1665|M.marinum_M ---MIA-------AAMLVSAVLLA---WPAAAEPPSCASLGGNVEGAQMC MUL_1902|M.ulcerans_Agy99 MRLMIA-------AAMLVSAVLLA---WPAAAEPPSCASLGGNVEGAQMC MAV_3901|M.avium_104 MRYLLA-------AALLAPAVLLG---WPAAAEPPSCAALGGSLEDGQMC Mvan_2092|M.vanbaalenii_PYR-1 MRIFAAALTAAGATAGLLAVPAAGLLAAPAAGAQSACAELGGTVDAEQTC Mflv_4267|M.gilvum_PYR-GCK MRFLAAALTAAAVSASLAAGPAALAQPAPPA-TPSACVALSGTVDTDDMC TH_2187|M.thermoresistible__bu MRILKT-------TAALLAGGLISCSIPGTAGAQTACDALGGTVADDRRC MSMEG_2331|M.smegmatis_MC2_155 MRISTV-------VGVLAAGVLIGGVAAPSAAAQSTCAELGGTVDADQIC MAB_1835c|M.abscessus_ATCC_199 MPYLSLR--SISASVLVTAASIFGFSGVAGAAPHDYCGDLKGTN-TGKTC : . * * * *. * Mb3062c|M.bovis_AF2122/97 HVHASGPKYMLDMTFPVDYPDQRALTDYITQNRDGFVNVAQGSPLRDQPY Rv3036c|M.tuberculosis_H37Rv HVHASGPKYMLDMTFPVDYPDQQALTDYITQNRDGFVNVAQGSPLRDQPY MMAR_1665|M.marinum_M HIHATGSTYTLDITFPQDYPDQQALTDYITQNRDGFVSVATGSGRRDQPY MUL_1902|M.ulcerans_Agy99 HIHATGSTYTLDITFPQDYPDQQALTDYITLNRDGFVSVATGSGRRDQPY MAV_3901|M.avium_104 RLRAAGPNYTINMVFPADYPDEQALTDYITQNRDGFVNVAQSSGGRDQPY Mvan_2092|M.vanbaalenii_PYR-1 HVHAENSTYRLDYTFPVDYPDQQALAAYLTQTRDGFVNVSEMPGSWNLPY Mflv_4267|M.gilvum_PYR-GCK LVQVENPTYRLDYSFPADYPDQQALTAYLTQTRDGFVNVAGMPGSWNLPY TH_2187|M.thermoresistible__bu EVHAETPTYLLDMVFPVDYPDQQALTDYLIQTRDGFVNVSEMPGSRNLPY MSMEG_2331|M.smegmatis_MC2_155 QVHTANATYRLDYTFSTTYPDQEAVVGYLSQTRDGFVNVSDMPGSRDQPY MAB_1835c|M.abscessus_ATCC_199 EIRLSDTGYSVDVTIPLNYPDQKSIAEYVAKTRDAFVNAAKSGAARSTTA :: . * :: :. ***:.::. *: .**.**..: . . Mb3062c|M.bovis_AF2122/97 QMDATSEQHSSGQPP---QATRSVVLKFFQDLGGAHPSTWYKAFNYNLAT Rv3036c|M.tuberculosis_H37Rv QMDATSEQHSSGQPP---QATRSVVLKFFQDLGGAHPSTWYKAFNYNLAT MMAR_1665|M.marinum_M QMDATTEQHAAGQPP---HNTRSVVLKFFQDLGGAHPFTWYKAFNYNLGT MUL_1902|M.ulcerans_Agy99 QMDATTEQHAAGQPP---HNTRSVVLKFFQDLGGAHPFTWHKAFNYNLGT MAV_3901|M.avium_104 QLEATTEQHSAGQPP---HNTRSVVLKFFQDVGGTRSSIWYKAFNYNLGT Mvan_2092|M.vanbaalenii_PYR-1 VLDGRGTGYRTGPDG---AGTRSVVFEVYENVGGAHPQTWFKAFNWDVAK Mflv_4267|M.gilvum_PYR-GCK VLDGRGTGYRTGPDD---GGTRSVVFEMYENVGGAHPQTWFKSFNWDVAK TH_2187|M.thermoresistible__bu ALDARATEYRSGDAA---TGTRSVVFEVYQNVGGAHPTTWYQAFNYDLRT MSMEG_2331|M.smegmatis_MC2_155 VLDARGSSYSSAVAPGLPARTQSLVLEVFQDVGGAQPETWYKSFNYDLVK MAB_1835c|M.abscessus_ATCC_199 QLSMKPTEYNSDLPP---RGTQTVVFKVYQTGGNGQPQTAYKAFNWDQSY :. : : *:::*::.:: *. :. .::**:: Mb3062c|M.bovis_AF2122/97 SQPITFDTLFVPGT--------TPLDSIYPIVQRELARQTG--------- Rv3036c|M.tuberculosis_H37Rv SQPITFDTLFVPGT--------TPLDSIYPIVQRELARQTG--------- MMAR_1665|M.marinum_M KQPITFDTLFAPGT--------TPLDAIYPIVQRELAHQTG--------- MUL_1902|M.ulcerans_Agy99 KQPITFDTLFAPGT--------TPLDAIYPIVQRELAHQTG--------- MAV_3901|M.avium_104 KQPLTFDNLFAPNT--------APLDAIFPIVQRDLERQTP--------- Mvan_2092|M.vanbaalenii_PYR-1 KAPITFDTLFRPDT--------KPLDVIFPIVQKDISRQLG--------- Mflv_4267|M.gilvum_PYR-GCK KAPITFDTLFKPGS--------EPLAVIFPIVRSDISRQLG--------- TH_2187|M.thermoresistible__bu RAPITFDTLFDPES--------APLEVIYPVVQRELQELTG--------- MSMEG_2331|M.smegmatis_MC2_155 RAPITFDTLFKPGS--------RPLDVIFPIVARELETQAG--------- MAB_1835c|M.abscessus_ATCC_199 RKPVLYTVPKDDKDDAPLWRVDDPLKTVAPIVQAQLQQQLAPPPVATPTP *: : ** : *:* :: Mb3062c|M.bovis_AF2122/97 ------------------------FGAAILPSTGLDPAHYQNFAITDDSL Rv3036c|M.tuberculosis_H37Rv ------------------------FGAAILPSTGLDPAHYQNFAITDDSL MMAR_1665|M.marinum_M ------------------------LGVAILPSNGLDPTHYQNFAITDTDV MUL_1902|M.ulcerans_Agy99 ------------------------LGVAILPSNGLDPTHYQNFAITDTDV MAV_3901|M.avium_104 ------------------------LGAAILPSTGHDPSHYQNFAITDDQL Mvan_2092|M.vanbaalenii_PYR-1 ------------------------VDAPISAADGLDPAKYQEFALTDDSL Mflv_4267|M.gilvum_PYR-GCK ------------------------IEAPITTADGLDPAKYTEFAITDDAV TH_2187|M.thermoresistible__bu ------------------------IDQPILPEDGLDPANYQNFALTDDEV MSMEG_2331|M.smegmatis_MC2_155 ------------------------IVQSISQSAGMDPTHYQNFAITDDSV MAB_1835c|M.abscessus_ATCC_199 TTTSGQPTTTTSTTTTSTTPPPPPPPLPFSPATLYDPANYQNFAVLNDGI .: **::* :**: : : Mb3062c|M.bovis_AF2122/97 IFYFAQGELLPSFVGACQAQVPRSAIPP--------------LAI----- Rv3036c|M.tuberculosis_H37Rv IFYFAQGELLPSFVGACQAQVPRSAIPP--------------LAI----- MMAR_1665|M.marinum_M IFYFAQGELLPSFAGATQAQVPRNAIPP--------------LAI----- MUL_1902|M.ulcerans_Agy99 IFYFAQGELLPSFAGATQAQVPRNAIPPPWRSEVHTGPASDSIAAAPMPS MAV_3901|M.avium_104 IFYFAPGEMLPAFGGPVQAQVPRNAIPP--------------LAI----- Mvan_2092|M.vanbaalenii_PYR-1 IFYFGQGEIMPGAGGALQATVPRSAVAA-------------MLAEPAVTQ Mflv_4267|M.gilvum_PYR-GCK IFYFGQGEIMAGAGGALQATIPRSEIAS-------------MLALEPVPV TH_2187|M.thermoresistible__bu IFFFSQGELLPHAAGVSQVSVPRTVLVN-------------LLTV----- MSMEG_2331|M.smegmatis_MC2_155 IFFFDRGALVADSAGALQASVPRWAVAS-------------LLA------ MAB_1835c|M.abscessus_ATCC_199 RFFFDQGAILPDSYGALQVLVPRSAIDP-------------MIA------ *:* * ::. * *. :** : :: Mb3062c|M.bovis_AF2122/97 -------------------------------------------------- Rv3036c|M.tuberculosis_H37Rv -------------------------------------------------- MMAR_1665|M.marinum_M -------------------------------------------------- MUL_1902|M.ulcerans_Agy99 VSWATHPMIGTTKATLCRASRYTLMMRSARNITMPPQKRSPIALSTQEGS MAV_3901|M.avium_104 -------------------------------------------------- Mvan_2092|M.vanbaalenii_PYR-1 G------------------------------------------------- Mflv_4267|M.gilvum_PYR-GCK TP------------------------------------------------ TH_2187|M.thermoresistible__bu -------------------------------------------------- MSMEG_2331|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1835c|M.abscessus_ATCC_199 -------------------------------------------------- Mb3062c|M.bovis_AF2122/97 ---- Rv3036c|M.tuberculosis_H37Rv ---- MMAR_1665|M.marinum_M ---- MUL_1902|M.ulcerans_Agy99 PQVW MAV_3901|M.avium_104 ---- Mvan_2092|M.vanbaalenii_PYR-1 ---- Mflv_4267|M.gilvum_PYR-GCK ---- TH_2187|M.thermoresistible__bu ---- MSMEG_2331|M.smegmatis_MC2_155 ---- MAB_1835c|M.abscessus_ATCC_199 ----