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M. vanbaalenii PYR-1 Mvan_2092 (-)

annotation: immunogenic protein MPB64/MPT64 precursor
coordinates: 2231578 - 2232312
length: 244

MRIFAAALTAAGATAGLLAVPAAGLLAAPAAGAQSACAELGGTVDAEQTCHVHAENSTYRLDYTFPVDYP
DQQALAAYLTQTRDGFVNVSEMPGSWNLPYVLDGRGTGYRTGPDGAGTRSVVFEVYENVGGAHPQTWFKA
FNWDVAKKAPITFDTLFRPDTKPLDVIFPIVQKDISRQLGVDAPISAADGLDPAKYQEFALTDDSLIFYF
GQGEIMPGAGGALQATVPRSAVAAMLAEPAVTQG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_2092--100% (244)immunogenic protein MPB64/MPT64 precursor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3062cTB22.22e-6756.82% (220) hypothetical protein Mb3062c
M. gilvum PYR-GCKMflv_4267-1e-10476.37% (237) immunogenic protein MPB64/MPT64 precursor
M. tuberculosis H37RvRv3036cTB22.27e-6857.27% (220) hypothetical protein Rv3036c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1835c-5e-3531.87% (273) immunogenic protein MPT64 precursor
M. marinum MMMAR_1665-1e-6353.08% (211) hypothetical protein MMAR_1665
M. avium 104MAV_3901-7e-5747.71% (218) immunogenic protein MPB64/MPT64
M. smegmatis MC2 155MSMEG_2331-9e-7558.33% (228) immunogenic protein MPB64/MPT64
M. thermoresistible (build 8)TH_2187-6e-7860.99% (223) PROBABLE CONSERVED SECRETED PROTEIN TB22.2
M. ulcerans Agy99MUL_1902-2e-6252.61% (211) hypothetical protein MUL_1902

CLUSTAL 2.0.9 multiple sequence alignment


Mb3062c|M.bovis_AF2122/97           MRYLIA-------TAVLVAVVLVG---WPAAGAPPSCAGLGGTVQAGQIC
Rv3036c|M.tuberculosis_H37Rv        MRYLIA-------TAVLVAVVLVG---WPAAGAPPSCAGLGGTVQAGQIC
MMAR_1665|M.marinum_M               ---MIA-------AAMLVSAVLLA---WPAAAEPPSCASLGGNVEGAQMC
MUL_1902|M.ulcerans_Agy99           MRLMIA-------AAMLVSAVLLA---WPAAAEPPSCASLGGNVEGAQMC
MAV_3901|M.avium_104                MRYLLA-------AALLAPAVLLG---WPAAAEPPSCAALGGSLEDGQMC
Mvan_2092|M.vanbaalenii_PYR-1       MRIFAAALTAAGATAGLLAVPAAGLLAAPAAGAQSACAELGGTVDAEQTC
Mflv_4267|M.gilvum_PYR-GCK          MRFLAAALTAAAVSASLAAGPAALAQPAPPA-TPSACVALSGTVDTDDMC
TH_2187|M.thermoresistible__bu      MRILKT-------TAALLAGGLISCSIPGTAGAQTACDALGGTVADDRRC
MSMEG_2331|M.smegmatis_MC2_155      MRISTV-------VGVLAAGVLIGGVAAPSAAAQSTCAELGGTVDADQIC
MAB_1835c|M.abscessus_ATCC_199      MPYLSLR--SISASVLVTAASIFGFSGVAGAAPHDYCGDLKGTN-TGKTC
                                                    : .           *     *  * *.      *

Mb3062c|M.bovis_AF2122/97           HVHASGPKYMLDMTFPVDYPDQRALTDYITQNRDGFVNVAQGSPLRDQPY
Rv3036c|M.tuberculosis_H37Rv        HVHASGPKYMLDMTFPVDYPDQQALTDYITQNRDGFVNVAQGSPLRDQPY
MMAR_1665|M.marinum_M               HIHATGSTYTLDITFPQDYPDQQALTDYITQNRDGFVSVATGSGRRDQPY
MUL_1902|M.ulcerans_Agy99           HIHATGSTYTLDITFPQDYPDQQALTDYITLNRDGFVSVATGSGRRDQPY
MAV_3901|M.avium_104                RLRAAGPNYTINMVFPADYPDEQALTDYITQNRDGFVNVAQSSGGRDQPY
Mvan_2092|M.vanbaalenii_PYR-1       HVHAENSTYRLDYTFPVDYPDQQALAAYLTQTRDGFVNVSEMPGSWNLPY
Mflv_4267|M.gilvum_PYR-GCK          LVQVENPTYRLDYSFPADYPDQQALTAYLTQTRDGFVNVAGMPGSWNLPY
TH_2187|M.thermoresistible__bu      EVHAETPTYLLDMVFPVDYPDQQALTDYLIQTRDGFVNVSEMPGSRNLPY
MSMEG_2331|M.smegmatis_MC2_155      QVHTANATYRLDYTFSTTYPDQEAVVGYLSQTRDGFVNVSDMPGSRDQPY
MAB_1835c|M.abscessus_ATCC_199      EIRLSDTGYSVDVTIPLNYPDQKSIAEYVAKTRDAFVNAAKSGAARSTTA
                                     ::   . * ::  :.  ***:.::. *:  .**.**..:      . . 

Mb3062c|M.bovis_AF2122/97           QMDATSEQHSSGQPP---QATRSVVLKFFQDLGGAHPSTWYKAFNYNLAT
Rv3036c|M.tuberculosis_H37Rv        QMDATSEQHSSGQPP---QATRSVVLKFFQDLGGAHPSTWYKAFNYNLAT
MMAR_1665|M.marinum_M               QMDATTEQHAAGQPP---HNTRSVVLKFFQDLGGAHPFTWYKAFNYNLGT
MUL_1902|M.ulcerans_Agy99           QMDATTEQHAAGQPP---HNTRSVVLKFFQDLGGAHPFTWHKAFNYNLGT
MAV_3901|M.avium_104                QLEATTEQHSAGQPP---HNTRSVVLKFFQDVGGTRSSIWYKAFNYNLGT
Mvan_2092|M.vanbaalenii_PYR-1       VLDGRGTGYRTGPDG---AGTRSVVFEVYENVGGAHPQTWFKAFNWDVAK
Mflv_4267|M.gilvum_PYR-GCK          VLDGRGTGYRTGPDD---GGTRSVVFEMYENVGGAHPQTWFKSFNWDVAK
TH_2187|M.thermoresistible__bu      ALDARATEYRSGDAA---TGTRSVVFEVYQNVGGAHPTTWYQAFNYDLRT
MSMEG_2331|M.smegmatis_MC2_155      VLDARGSSYSSAVAPGLPARTQSLVLEVFQDVGGAQPETWYKSFNYDLVK
MAB_1835c|M.abscessus_ATCC_199      QLSMKPTEYNSDLPP---RGTQTVVFKVYQTGGNGQPQTAYKAFNWDQSY
                                     :.     : :         *:::*::.::  *. :.   .::**::   

Mb3062c|M.bovis_AF2122/97           SQPITFDTLFVPGT--------TPLDSIYPIVQRELARQTG---------
Rv3036c|M.tuberculosis_H37Rv        SQPITFDTLFVPGT--------TPLDSIYPIVQRELARQTG---------
MMAR_1665|M.marinum_M               KQPITFDTLFAPGT--------TPLDAIYPIVQRELAHQTG---------
MUL_1902|M.ulcerans_Agy99           KQPITFDTLFAPGT--------TPLDAIYPIVQRELAHQTG---------
MAV_3901|M.avium_104                KQPLTFDNLFAPNT--------APLDAIFPIVQRDLERQTP---------
Mvan_2092|M.vanbaalenii_PYR-1       KAPITFDTLFRPDT--------KPLDVIFPIVQKDISRQLG---------
Mflv_4267|M.gilvum_PYR-GCK          KAPITFDTLFKPGS--------EPLAVIFPIVRSDISRQLG---------
TH_2187|M.thermoresistible__bu      RAPITFDTLFDPES--------APLEVIYPVVQRELQELTG---------
MSMEG_2331|M.smegmatis_MC2_155      RAPITFDTLFKPGS--------RPLDVIFPIVARELETQAG---------
MAB_1835c|M.abscessus_ATCC_199      RKPVLYTVPKDDKDDAPLWRVDDPLKTVAPIVQAQLQQQLAPPPVATPTP
                                      *: :                 **  : *:*  ::              

Mb3062c|M.bovis_AF2122/97           ------------------------FGAAILPSTGLDPAHYQNFAITDDSL
Rv3036c|M.tuberculosis_H37Rv        ------------------------FGAAILPSTGLDPAHYQNFAITDDSL
MMAR_1665|M.marinum_M               ------------------------LGVAILPSNGLDPTHYQNFAITDTDV
MUL_1902|M.ulcerans_Agy99           ------------------------LGVAILPSNGLDPTHYQNFAITDTDV
MAV_3901|M.avium_104                ------------------------LGAAILPSTGHDPSHYQNFAITDDQL
Mvan_2092|M.vanbaalenii_PYR-1       ------------------------VDAPISAADGLDPAKYQEFALTDDSL
Mflv_4267|M.gilvum_PYR-GCK          ------------------------IEAPITTADGLDPAKYTEFAITDDAV
TH_2187|M.thermoresistible__bu      ------------------------IDQPILPEDGLDPANYQNFALTDDEV
MSMEG_2331|M.smegmatis_MC2_155      ------------------------IVQSISQSAGMDPTHYQNFAITDDSV
MAB_1835c|M.abscessus_ATCC_199      TTTSGQPTTTTSTTTTSTTPPPPPPPLPFSPATLYDPANYQNFAVLNDGI
                                                               .:      **::* :**: :  :

Mb3062c|M.bovis_AF2122/97           IFYFAQGELLPSFVGACQAQVPRSAIPP--------------LAI-----
Rv3036c|M.tuberculosis_H37Rv        IFYFAQGELLPSFVGACQAQVPRSAIPP--------------LAI-----
MMAR_1665|M.marinum_M               IFYFAQGELLPSFAGATQAQVPRNAIPP--------------LAI-----
MUL_1902|M.ulcerans_Agy99           IFYFAQGELLPSFAGATQAQVPRNAIPPPWRSEVHTGPASDSIAAAPMPS
MAV_3901|M.avium_104                IFYFAPGEMLPAFGGPVQAQVPRNAIPP--------------LAI-----
Mvan_2092|M.vanbaalenii_PYR-1       IFYFGQGEIMPGAGGALQATVPRSAVAA-------------MLAEPAVTQ
Mflv_4267|M.gilvum_PYR-GCK          IFYFGQGEIMAGAGGALQATIPRSEIAS-------------MLALEPVPV
TH_2187|M.thermoresistible__bu      IFFFSQGELLPHAAGVSQVSVPRTVLVN-------------LLTV-----
MSMEG_2331|M.smegmatis_MC2_155      IFFFDRGALVADSAGALQASVPRWAVAS-------------LLA------
MAB_1835c|M.abscessus_ATCC_199      RFFFDQGAILPDSYGALQVLVPRSAIDP-------------MIA------
                                     *:*  * ::.   *  *. :**  :                ::      

Mb3062c|M.bovis_AF2122/97           --------------------------------------------------
Rv3036c|M.tuberculosis_H37Rv        --------------------------------------------------
MMAR_1665|M.marinum_M               --------------------------------------------------
MUL_1902|M.ulcerans_Agy99           VSWATHPMIGTTKATLCRASRYTLMMRSARNITMPPQKRSPIALSTQEGS
MAV_3901|M.avium_104                --------------------------------------------------
Mvan_2092|M.vanbaalenii_PYR-1       G-------------------------------------------------
Mflv_4267|M.gilvum_PYR-GCK          TP------------------------------------------------
TH_2187|M.thermoresistible__bu      --------------------------------------------------
MSMEG_2331|M.smegmatis_MC2_155      --------------------------------------------------
MAB_1835c|M.abscessus_ATCC_199      --------------------------------------------------
                                                                                      

Mb3062c|M.bovis_AF2122/97           ----
Rv3036c|M.tuberculosis_H37Rv        ----
MMAR_1665|M.marinum_M               ----
MUL_1902|M.ulcerans_Agy99           PQVW
MAV_3901|M.avium_104                ----
Mvan_2092|M.vanbaalenii_PYR-1       ----
Mflv_4267|M.gilvum_PYR-GCK          ----
TH_2187|M.thermoresistible__bu      ----
MSMEG_2331|M.smegmatis_MC2_155      ----
MAB_1835c|M.abscessus_ATCC_199      ----