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MRLMIAAAMLVSAVLLAWPAAAEPPSCASLGGNVEGAQMCHIHATGSTYTLDITFPQDYPDQQALTDYIT LNRDGFVSVATGSGRRDQPYQMDATTEQHAAGQPPHNTRSVVLKFFQDLGGAHPFTWHKAFNYNLGTKQP ITFDTLFAPGTTPLDAIYPIVQRELAHQTGLGVAILPSNGLDPTHYQNFAITDTDVIFYFAQGELLPSFA GATQAQVPRNAIPPPWRSEVHTGPASDSIAAAPMPSVSWATHPMIGTTKATLCRASRYTLMMRSARNITM PPQKRSPIALSTQEGSPQVW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_1902 | - | - | 100% (300) | hypothetical protein MUL_1902 |
M. ulcerans Agy99 | MUL_5032 | mpt64 | 5e-46 | 42.22% (225) | immunogenic protein Mpt64 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb3062c | TB22.2 | 1e-103 | 77.23% (224) | hypothetical protein Mb3062c |
M. gilvum PYR-GCK | Mflv_4267 | - | 1e-55 | 47.62% (231) | immunogenic protein MPB64/MPT64 precursor |
M. tuberculosis H37Rv | Rv3036c | TB22.2 | 1e-103 | 77.68% (224) | hypothetical protein Rv3036c |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_1835c | - | 2e-27 | 29.43% (265) | immunogenic protein MPT64 precursor |
M. marinum M | MMAR_1665 | - | 1e-128 | 99.10% (221) | hypothetical protein MMAR_1665 |
M. avium 104 | MAV_3901 | - | 1e-97 | 72.77% (224) | immunogenic protein MPB64/MPT64 |
M. smegmatis MC2 155 | MSMEG_2331 | - | 8e-61 | 50.44% (228) | immunogenic protein MPB64/MPT64 |
M. thermoresistible (build 8) | TH_2187 | - | 1e-63 | 50.67% (225) | PROBABLE CONSERVED SECRETED PROTEIN TB22.2 |
M. vanbaalenii PYR-1 | Mvan_2092 | - | 3e-62 | 52.61% (211) | immunogenic protein MPB64/MPT64 precursor |
CLUSTAL 2.0.9 multiple sequence alignment MUL_1902|M.ulcerans_Agy99 MRLMIA-------AAMLVSAVLLA---WPAAAEPPSCASLGGNVEGAQMC MMAR_1665|M.marinum_M ---MIA-------AAMLVSAVLLA---WPAAAEPPSCASLGGNVEGAQMC MAV_3901|M.avium_104 MRYLLA-------AALLAPAVLLG---WPAAAEPPSCAALGGSLEDGQMC Mb3062c|M.bovis_AF2122/97 MRYLIA-------TAVLVAVVLVG---WPAAGAPPSCAGLGGTVQAGQIC Rv3036c|M.tuberculosis_H37Rv MRYLIA-------TAVLVAVVLVG---WPAAGAPPSCAGLGGTVQAGQIC Mflv_4267|M.gilvum_PYR-GCK MRFLAAALTAAAVSASLAAGPAALAQPAPPA-TPSACVALSGTVDTDDMC Mvan_2092|M.vanbaalenii_PYR-1 MRIFAAALTAAGATAGLLAVPAAGLLAAPAAGAQSACAELGGTVDAEQTC TH_2187|M.thermoresistible__bu MRILKT-------TAALLAGGLISCSIPGTAGAQTACDALGGTVADDRRC MSMEG_2331|M.smegmatis_MC2_155 MRISTV-------VGVLAAGVLIGGVAAPSAAAQSTCAELGGTVDADQIC MAB_1835c|M.abscessus_ATCC_199 MPYLSLR--SISASVLVTAASIFGFSGVAGAAPHDYCGDLKGTN-TGKTC : . * * * *. * MUL_1902|M.ulcerans_Agy99 HIHATGSTYTLDITFPQDYPDQQALTDYITLNRDGFVSVATGSGRRDQPY MMAR_1665|M.marinum_M HIHATGSTYTLDITFPQDYPDQQALTDYITQNRDGFVSVATGSGRRDQPY MAV_3901|M.avium_104 RLRAAGPNYTINMVFPADYPDEQALTDYITQNRDGFVNVAQSSGGRDQPY Mb3062c|M.bovis_AF2122/97 HVHASGPKYMLDMTFPVDYPDQRALTDYITQNRDGFVNVAQGSPLRDQPY Rv3036c|M.tuberculosis_H37Rv HVHASGPKYMLDMTFPVDYPDQQALTDYITQNRDGFVNVAQGSPLRDQPY Mflv_4267|M.gilvum_PYR-GCK LVQVENPTYRLDYSFPADYPDQQALTAYLTQTRDGFVNVAGMPGSWNLPY Mvan_2092|M.vanbaalenii_PYR-1 HVHAENSTYRLDYTFPVDYPDQQALAAYLTQTRDGFVNVSEMPGSWNLPY TH_2187|M.thermoresistible__bu EVHAETPTYLLDMVFPVDYPDQQALTDYLIQTRDGFVNVSEMPGSRNLPY MSMEG_2331|M.smegmatis_MC2_155 QVHTANATYRLDYTFSTTYPDQEAVVGYLSQTRDGFVNVSDMPGSRDQPY MAB_1835c|M.abscessus_ATCC_199 EIRLSDTGYSVDVTIPLNYPDQKSIAEYVAKTRDAFVNAAKSGAARSTTA :: . * :: :. ***:.::. *: .**.**..: . . MUL_1902|M.ulcerans_Agy99 QMDATTEQHAAGQPP---HNTRSVVLKFFQDLGGAHPFTWHKAFNYNLGT MMAR_1665|M.marinum_M QMDATTEQHAAGQPP---HNTRSVVLKFFQDLGGAHPFTWYKAFNYNLGT MAV_3901|M.avium_104 QLEATTEQHSAGQPP---HNTRSVVLKFFQDVGGTRSSIWYKAFNYNLGT Mb3062c|M.bovis_AF2122/97 QMDATSEQHSSGQPP---QATRSVVLKFFQDLGGAHPSTWYKAFNYNLAT Rv3036c|M.tuberculosis_H37Rv QMDATSEQHSSGQPP---QATRSVVLKFFQDLGGAHPSTWYKAFNYNLAT Mflv_4267|M.gilvum_PYR-GCK VLDGRGTGYRTGPDD---GGTRSVVFEMYENVGGAHPQTWFKSFNWDVAK Mvan_2092|M.vanbaalenii_PYR-1 VLDGRGTGYRTGPDG---AGTRSVVFEVYENVGGAHPQTWFKAFNWDVAK TH_2187|M.thermoresistible__bu ALDARATEYRSGDAA---TGTRSVVFEVYQNVGGAHPTTWYQAFNYDLRT MSMEG_2331|M.smegmatis_MC2_155 VLDARGSSYSSAVAPGLPARTQSLVLEVFQDVGGAQPETWYKSFNYDLVK MAB_1835c|M.abscessus_ATCC_199 QLSMKPTEYNSDLPP---RGTQTVVFKVYQTGGNGQPQTAYKAFNWDQSY :. : : *:::*::.:: *. :. .::**:: MUL_1902|M.ulcerans_Agy99 KQPITFDTLFAPGT--------TPLDAIYPIVQRELAHQTG--------- MMAR_1665|M.marinum_M KQPITFDTLFAPGT--------TPLDAIYPIVQRELAHQTG--------- MAV_3901|M.avium_104 KQPLTFDNLFAPNT--------APLDAIFPIVQRDLERQTP--------- Mb3062c|M.bovis_AF2122/97 SQPITFDTLFVPGT--------TPLDSIYPIVQRELARQTG--------- Rv3036c|M.tuberculosis_H37Rv SQPITFDTLFVPGT--------TPLDSIYPIVQRELARQTG--------- Mflv_4267|M.gilvum_PYR-GCK KAPITFDTLFKPGS--------EPLAVIFPIVRSDISRQLG--------- Mvan_2092|M.vanbaalenii_PYR-1 KAPITFDTLFRPDT--------KPLDVIFPIVQKDISRQLG--------- TH_2187|M.thermoresistible__bu RAPITFDTLFDPES--------APLEVIYPVVQRELQELTG--------- MSMEG_2331|M.smegmatis_MC2_155 RAPITFDTLFKPGS--------RPLDVIFPIVARELETQAG--------- MAB_1835c|M.abscessus_ATCC_199 RKPVLYTVPKDDKDDAPLWRVDDPLKTVAPIVQAQLQQQLAPPPVATPTP *: : ** : *:* :: MUL_1902|M.ulcerans_Agy99 ------------------------LGVAILPSNGLDPTHYQNFAITDTDV MMAR_1665|M.marinum_M ------------------------LGVAILPSNGLDPTHYQNFAITDTDV MAV_3901|M.avium_104 ------------------------LGAAILPSTGHDPSHYQNFAITDDQL Mb3062c|M.bovis_AF2122/97 ------------------------FGAAILPSTGLDPAHYQNFAITDDSL Rv3036c|M.tuberculosis_H37Rv ------------------------FGAAILPSTGLDPAHYQNFAITDDSL Mflv_4267|M.gilvum_PYR-GCK ------------------------IEAPITTADGLDPAKYTEFAITDDAV Mvan_2092|M.vanbaalenii_PYR-1 ------------------------VDAPISAADGLDPAKYQEFALTDDSL TH_2187|M.thermoresistible__bu ------------------------IDQPILPEDGLDPANYQNFALTDDEV MSMEG_2331|M.smegmatis_MC2_155 ------------------------IVQSISQSAGMDPTHYQNFAITDDSV MAB_1835c|M.abscessus_ATCC_199 TTTSGQPTTTTSTTTTSTTPPPPPPPLPFSPATLYDPANYQNFAVLNDGI .: **::* :**: : : MUL_1902|M.ulcerans_Agy99 IFYFAQGELLPSFAGATQAQVPRNAIPPPWRSEVHTGPASDSIAAAPMPS MMAR_1665|M.marinum_M IFYFAQGELLPSFAGATQAQVPRNAIPP--------------LAI----- MAV_3901|M.avium_104 IFYFAPGEMLPAFGGPVQAQVPRNAIPP--------------LAI----- Mb3062c|M.bovis_AF2122/97 IFYFAQGELLPSFVGACQAQVPRSAIPP--------------LAI----- Rv3036c|M.tuberculosis_H37Rv IFYFAQGELLPSFVGACQAQVPRSAIPP--------------LAI----- Mflv_4267|M.gilvum_PYR-GCK IFYFGQGEIMAGAGGALQATIPRSEIAS-------------MLALEPVPV Mvan_2092|M.vanbaalenii_PYR-1 IFYFGQGEIMPGAGGALQATVPRSAVAA-------------MLAEPAVTQ TH_2187|M.thermoresistible__bu IFFFSQGELLPHAAGVSQVSVPRTVLVN-------------LLTV----- MSMEG_2331|M.smegmatis_MC2_155 IFFFDRGALVADSAGALQASVPRWAVAS-------------LLA------ MAB_1835c|M.abscessus_ATCC_199 RFFFDQGAILPDSYGALQVLVPRSAIDP-------------MIA------ *:* * ::. * *. :** : :: MUL_1902|M.ulcerans_Agy99 VSWATHPMIGTTKATLCRASRYTLMMRSARNITMPPQKRSPIALSTQEGS MMAR_1665|M.marinum_M -------------------------------------------------- MAV_3901|M.avium_104 -------------------------------------------------- Mb3062c|M.bovis_AF2122/97 -------------------------------------------------- Rv3036c|M.tuberculosis_H37Rv -------------------------------------------------- Mflv_4267|M.gilvum_PYR-GCK TP------------------------------------------------ Mvan_2092|M.vanbaalenii_PYR-1 G------------------------------------------------- TH_2187|M.thermoresistible__bu -------------------------------------------------- MSMEG_2331|M.smegmatis_MC2_155 -------------------------------------------------- MAB_1835c|M.abscessus_ATCC_199 -------------------------------------------------- MUL_1902|M.ulcerans_Agy99 PQVW MMAR_1665|M.marinum_M ---- MAV_3901|M.avium_104 ---- Mb3062c|M.bovis_AF2122/97 ---- Rv3036c|M.tuberculosis_H37Rv ---- Mflv_4267|M.gilvum_PYR-GCK ---- Mvan_2092|M.vanbaalenii_PYR-1 ---- TH_2187|M.thermoresistible__bu ---- MSMEG_2331|M.smegmatis_MC2_155 ---- MAB_1835c|M.abscessus_ATCC_199 ----