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VLESLAADAVALGERVPRAVLGIAGCPGAGKSTLVQWLLERIGQLRGAGWVAHVPMDGFHLADDQLRRLG RLGRKGAPDTFDAAGYARLLDRVREDTDIDVYVPGFDRTLEQPLAAALVVHPTARLVITEGNYLLLGTAD WVRARQAMDQVWFVSADDQTRTARLTARHVEFGKSPDAARAWVTTVDQRNAELVSQTATAADRVILNGAQ GWAISA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2086 | frcK | - | 100% (216) | putative fructose transport system kinase |
| M. vanbaalenii PYR-1 | Mvan_4658 | - | 4e-06 | 28.46% (123) | pantothenate kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1122c | coaA | 5e-05 | 25.88% (170) | pantothenate kinase |
| M. gilvum PYR-GCK | Mflv_4273 | frcK | 5e-82 | 69.16% (214) | putative fructose transport system kinase |
| M. tuberculosis H37Rv | Rv1092c | coaA | 5e-05 | 25.88% (170) | pantothenate kinase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1234c | - | 6e-05 | 31.18% (93) | pantothenate kinase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6800 | frcK | 3e-43 | 45.63% (206) | putative fructose transport system kinase |
| M. thermoresistible (build 8) | TH_2624 | - | 2e-44 | 46.98% (215) | PUTATIVE phosphoribulokinase/uridine kinase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_2086|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_4273|M.gilvum_PYR-GCK --------------------------------------------------
TH_2624|M.thermoresistible__bu --------------------------------------------------
MSMEG_6800|M.smegmatis_MC2_155 --------------------------------------------------
Mb1122c|M.bovis_AF2122/97 MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
Rv1092c|M.tuberculosis_H37Rv MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVE
MAB_1234c|M.abscessus_ATCC_199 MPRLSEPSPYVEFDRKQWRALRKSTPLVLTEEELIGLRGLGEQIDLTEVA
Mvan_2086|M.vanbaalenii_PYR-1 ------------------MLESLAADAVALGERVP----RAVLGIAGCPG
Mflv_4273|M.gilvum_PYR-GCK -------------MDNPPGSESLAAEAVGLGDGTH----RAVLGIAGSPG
TH_2624|M.thermoresistible__bu ------------VRTTADAVAELTDDVHRLLNAHPG---RVVLGLVGPPG
MSMEG_6800|M.smegmatis_MC2_155 ------------MTNVQDVQEATLDQMVEWAKALVVPGKRRILGLTGAPA
Mb1122c|M.bovis_AF2122/97 EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
Rv1092c|M.tuberculosis_H37Rv EVYLPLARLIHLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVA
MAB_1234c|M.abscessus_ATCC_199 EVYLPLARLIHLQVAARQRLFAATATFLG--DQHPDRLVPFVIGVAGSVA
. ::*:.* .
Mvan_2086|M.vanbaalenii_PYR-1 AGKSTLVQWLLERIGQLRGAGWVAHVPMDGFHLADDQLRRLGRLGRKGAP
Mflv_4273|M.gilvum_PYR-GCK AGKSTLVELLAARIRQMRGPGWVAHVPMDGFHLADAQLRRLGLLDRKGAP
TH_2624|M.thermoresistible__bu AGKSTLAQRLVREFGPG-APEGVGYVPMDGFHLSNAQLDRLGRRHRKGAP
MSMEG_6800|M.smegmatis_MC2_155 AGKSTVAEQLVAAL----GPEVAVLVPMDGFHLANEVLIDLGRRDRKGAH
Mb1122c|M.bovis_AF2122/97 VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFP
Rv1092c|M.tuberculosis_H37Rv VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFP
MAB_1234c|M.abscessus_ATCC_199 VGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELSRRNIMHRKGFP
.**** .. * : . *. *** .: * . ***
Mvan_2086|M.vanbaalenii_PYR-1 DTFDAAGYARLLDRVRED-TDI-DVYVPGFDRTLEQPLAAALVVHPTARL
Mflv_4273|M.gilvum_PYR-GCK ETFDAVGYAHALHRIRTD-VDS-DVYVPGFDRDLEQPLAAALVVPASARL
TH_2624|M.thermoresistible__bu DTFDVDGYLAVLQQISHS-HRIRDVYVPGFDRTLDEPVAARHVVPADARV
MSMEG_6800|M.smegmatis_MC2_155 DTFDDGGYARLIATLRAQRLGDPVVYAPRFHREIEESIASSIPVASTVPL
Mb1122c|M.bovis_AF2122/97 ESYNRRALMRFVTSVKSG---SDYACAPVYSHLHYDIIPGAEQVVRHPDI
Rv1092c|M.tuberculosis_H37Rv ESYNRRALMRFVTSVKSG---SDYACAPVYSHLHYDIIPGAEQVVRHPDI
MAB_1234c|M.abscessus_ATCC_199 ESYNRRGLLRFVTEVKSG---AREVTAPVYSHLLYDIIKNEKHVVQQPDI
:::: . : : . .* : : : : * :
Mvan_2086|M.vanbaalenii_PYR-1 VITEGNYLLLGTADWVRARQAMDQVWFVSADDQTRTARLTARHVEFGKSP
Mflv_4273|M.gilvum_PYR-GCK VLTEGNYLLLDQPAWRRVRRSLDQTWFVSADDSLRVERLIARHVEFGKTA
TH_2624|M.thermoresistible__bu IVTEGNYLALPSPGWAAVRDLLDWVVYLDSPAPLRRRRLIERHIRGGRGA
MSMEG_6800|M.smegmatis_MC2_155 VVTEGNYLLLDRDAWPTARSCIDEVWFLTLDTEVRRARLRRRHEAFGKSP
Mb1122c|M.bovis_AF2122/97 LILEG-LNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTA
Rv1092c|M.tuberculosis_H37Rv LILEG-LNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLAMRTTA
MAB_1234c|M.abscessus_ATCC_199 LILEG-LNVLQTGPTLMVSDLFDFSIYVDARIEDIEQWYISRFLAMRSTS
:: ** * . :* :: *. .
Mvan_2086|M.vanbaalenii_PYR-1 DA---------------------ARAWVTTVDQRNAELVSQTATAADRVI
Mflv_4273|M.gilvum_PYR-GCK AA---------------------ARAWADTVDEANAALVTSTAASADRIV
TH_2624|M.thermoresistible__bu AE---------------------AARWVDTVDDPNAELIAAGRGRCDRVL
MSMEG_6800|M.smegmatis_MC2_155 RD---------------------AERWALGPDERNAQLIESTAGRADRIV
Mb1122c|M.bovis_AF2122/97 FADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVL
Rv1092c|M.tuberculosis_H37Rv FADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVL
MAB_1234c|M.abscessus_ATCC_199 FANPSSHFHHYAKLSDKQATLAAQEIWHSINLPNLLENILPTRPRATLVL
* : . ::
Mvan_2086|M.vanbaalenii_PYR-1 LNGAQGWAISA-----
Mflv_4273|M.gilvum_PYR-GCK VNGTRGWSFGACLR--
TH_2624|M.thermoresistible__bu EIGDTGVQSAGS----
MSMEG_6800|M.smegmatis_MC2_155 RVP-------------
Mb1122c|M.bovis_AF2122/97 RKDADHSINRLRLRKL
Rv1092c|M.tuberculosis_H37Rv RKDADHSINRLRLRKL
MAB_1234c|M.abscessus_ATCC_199 RKDADHSINRLRLRKL