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MTATQQEAQRTAPAPKPLGYRAIDVDNHYYEPIDSFTRYLPKEFSRRGVQMYQDGKRTWAVMGGRVNTFI PNPTFDPIIEPGCLDLLFRGEIPEGVDPASLMKVDRISDHPEYRNRDARVKILDKQNLETVFMLPTFACG VEEALKHDVEATMVSVHAFNLWLDEDWGFNRPDHRILAAPIISLADPDKAVEEAEFVLSRGAKVVCVRPA PVPGVVKPRSLGDPVHDPVWARLAEAGVPVVFHLSDSGYMAIPALWGGKDTFEGFGKRDPLDMVVMDDRA IHDSIASMIVHQVFTRHPTLKVASIENGSYFVYRLIKRLKKSANNAPYHYKEDPVEQLRNNVWIAPYYED DVKLLADTIGVDKILFGSDWPHGEGLADPTSFTADIPQFPEFSHEDTRKVMRDNALTLVGTHVSA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1994 | - | - | 100% (415) | amidohydrolase 2 |
| M. vanbaalenii PYR-1 | Mvan_2602 | - | 3e-78 | 40.86% (394) | amidohydrolase 2 |
| M. vanbaalenii PYR-1 | Mvan_4134 | - | 8e-72 | 36.60% (388) | amidohydrolase 2 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4350 | - | 0.0 | 88.92% (406) | amidohydrolase 2 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4014 | - | 1e-162 | 67.17% (399) | metal-dependent hydrolase |
| M. avium 104 | MAV_1591 | - | 0.0 | 77.14% (398) | amidohydrolase family protein |
| M. smegmatis MC2 155 | MSMEG_2230 | - | 0.0 | 86.36% (396) | amidohydrolase family protein |
| M. thermoresistible (build 8) | TH_4037 | - | 0.0 | 86.43% (398) | PUTATIVE amidohydrolase 2 |
| M. ulcerans Agy99 | MUL_3878 | - | 1e-162 | 67.17% (399) | metal-dependent hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4350|M.gilvum_PYR-GCK MTIQQEERV----AAQRLDYRAIDVDNHYYEPIDSFTRHLPKEFRSRGVQ
MSMEG_2230|M.smegmatis_MC2_155 MTTDPE----------RLPYLAVDVDNHYYEPLDAFTRHLPKEFRSRGVQ
Mvan_1994|M.vanbaalenii_PYR-1 MTATQQEAQRTAPAPKPLGYRAIDVDNHYYEPIDSFTRYLPKEFSRRGVQ
TH_4037|M.thermoresistible__bu -VIMTE-----------LDYRAIDVDNHYYEPLDAFTRYLPKEFTRRGVQ
MAV_1591|M.avium_104 MT--------------ALNYRVIDVDNHYYEPLDSFTRHLDKKFKRRGVQ
MMAR_4014|M.marinum_M MDS--------------LGYKAIDVDNHYYEPLDAFTRHLDKKFRRRGVQ
MUL_3878|M.ulcerans_Agy99 MDS--------------LGYKAIDVDNHYYEPLDAFTRHLDKKFRRRGVQ
* * .:*********:*:***:* *:* ****
Mflv_4350|M.gilvum_PYR-GCK MLNDGKRTYAVFGGVINHFIPNPTFDPIIEPGCLDLLFRGEIPEGVDPAS
MSMEG_2230|M.smegmatis_MC2_155 MLTDGKRTYAVFGGVVNHFIPNPSFDPIIEPGCLDLLFRGEVPEGVDPAS
Mvan_1994|M.vanbaalenii_PYR-1 MYQDGKRTWAVMGGRVNTFIPNPTFDPIIEPGCLDLLFRGEIPEGVDPAS
TH_4037|M.thermoresistible__bu MLTDGKRTFALMGEKVNHFIPNPTFDPIIEPGCLDLLFRGEIPEGVDPGS
MAV_1591|M.avium_104 MLSDGKRTWAVIGDRVNHFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPAS
MMAR_4014|M.marinum_M MVTDGRHTQVIIGDRVNRFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPAS
MUL_3878|M.ulcerans_Agy99 LVTDGRHTQVIIGDRVNRFIPNPTFDPIIVPGCLDLLFRGEIPDGVDPAS
: **::* .::* :* *****:***** ***********:*:****.*
Mflv_4350|M.gilvum_PYR-GCK LMKVDRLSEHPEYQNRDARVKILDKQNLETVFMLPTFACGVEEGLKHDIP
MSMEG_2230|M.smegmatis_MC2_155 LMKVDRLTDHPEYQNRDARVAVLDRQRLETVFMLPTFACGVEEGLKHDIG
Mvan_1994|M.vanbaalenii_PYR-1 LMKVDRISDHPEYRNRDARVKILDKQNLETVFMLPTFACGVEEALKHDVE
TH_4037|M.thermoresistible__bu LMKVDRLANHPEYQNRDERVKILDKQNLETVFMLPTFACGVEEGLKHDIE
MAV_1591|M.avium_104 LMKVERLADHPEYQNRDARIAVMDEQDIETAFMLPTFGCGVEEALKHDIE
MMAR_4014|M.marinum_M LMKVEKLELRLEYRNRDARVAVVESQGIETIFMFPTFGCGVEEALKADIE
MUL_3878|M.ulcerans_Agy99 LMKVEKLELRPEYRNRDARVVVVESQGIETIFMFPTFGCGVEEALKADIE
****::: : **:*** *: ::: * :** **:***.*****.** *:
Mflv_4350|M.gilvum_PYR-GCK ATMASVHAFNLWLDEDWGFNRPDGRILSAPIISLADVQKAVEEVEFVLSR
MSMEG_2230|M.smegmatis_MC2_155 ATMASIHAFNLWLDEDWGFDRPDGRIIAAPIISLADPEKAVGEVEFVLGR
Mvan_1994|M.vanbaalenii_PYR-1 ATMVSVHAFNLWLDEDWGFNRPDHRILAAPIISLADPDKAVEEAEFVLSR
TH_4037|M.thermoresistible__bu ATMVSLHAFNLWLDEDWGFDRPDGRILSAPMISLADPEKAVEEVEFVLNR
MAV_1591|M.avium_104 ATMASVHAFNLWLDEDWGFDRPDHRIIAAPIVSLADPTRAVEEVDFVLAR
MMAR_4014|M.marinum_M ATAASLHAFNLWLDEDWGFDRPDHRIIAAPMISLADPEKALQEVEFVLER
MUL_3878|M.ulcerans_Agy99 ATAASLHAFNLWLDEDWGFDRPDHRIIAAPMISLADPEKALQEVEFVLER
** .*:*************:*** **::**::**** :*: *.:*** *
Mflv_4350|M.gilvum_PYR-GCK GAKIVCVRPAPVPGEVRPRSLGDPVHDPVWARLAEAGVPVVFHLSDSGYT
MSMEG_2230|M.smegmatis_MC2_155 GAKLVCVRPAPVPGLVRPRSLGDPVHDPVWARLAEAGVPVVFHLSDSGYM
Mvan_1994|M.vanbaalenii_PYR-1 GAKVVCVRPAPVPGVVKPRSLGDPVHDPVWARLAEAGVPVVFHLSDSGYM
TH_4037|M.thermoresistible__bu GARIVCVRPAPVPGVVKPRSLGDPVHDPVWARLAEAGVPVIFHLSDSGYL
MAV_1591|M.avium_104 GAKLVLVRPAPVPGLVKPRSLGDRSHDPVWARLAEAGVPVGFHLSDSGYL
MMAR_4014|M.marinum_M GARMVHVRPAPVPGVPRNRSLGHRSHDRVWARLAEANVPVAFHLGDSGYL
MUL_3878|M.ulcerans_Agy99 GARMVHVRPAPVPGVPRNRSLGHRSHDRVWARLAEANVPVAFHLGDSGYL
**::* ******** : ****. ** ********.*** ***.****
Mflv_4350|M.gilvum_PYR-GCK AIPALWGGSGVFKGFGKR-DPLDMVIMDDRAIHDTIASMIVHQVFTRHPK
MSMEG_2230|M.smegmatis_MC2_155 AIPALWGGSGVFKGFGKR-DPLDMVIMDDRAIHDTIASMIVHQVFTRHPK
Mvan_1994|M.vanbaalenii_PYR-1 AIPALWGGKDTFEGFGKR-DPLDMVVMDDRAIHDSIASMIVHQVFTRHPT
TH_4037|M.thermoresistible__bu AISALWGGTGTFEGFGKR-DPLDNVLLDDRAIHDTMASMIVHQVFTRHPN
MAV_1591|M.avium_104 HIAAAWGGKSTFEGFGAK-DPLDQVLLDDRAIHDTMASMIVHGVFTRHPK
MMAR_4014|M.marinum_M EIAGMWGGKETFEPFAAPPDPLDKILVDDRAIHDTMASLIVHGVFDRHPT
MUL_3878|M.ulcerans_Agy99 EIAGMWGGKETFEPFAAPPDPLDKILVDDRAIHDTMASLIVHGVFDRHPT
*.. ***. .*: *. **** :::*******::**:*** ** ***.
Mflv_4350|M.gilvum_PYR-GCK LKVASIENGSYFVYRLIKRLKKSANNAPYHYKEDPVEQLRNNVWIAPYYE
MSMEG_2230|M.smegmatis_MC2_155 LKVVSIENGSYFVYRLIKRLKKSANNAPYHYKEDPVEQLKNHVWIAPYYE
Mvan_1994|M.vanbaalenii_PYR-1 LKVASIENGSYFVYRLIKRLKKSANNAPYHYKEDPVEQLRNNVWIAPYYE
TH_4037|M.thermoresistible__bu LKVASIENGSYFVYRLIKRLKKAANTAPSHFKEDPVEQLKNNVWIAPYYE
MAV_1591|M.avium_104 LKAVSIENGSYFVHRLIKRLKKAANTQPQYFPEDPVEQLRNNVWIAPYYE
MMAR_4014|M.marinum_M LRVASIENGSEWVHRLAKRLKKLANQHPRSFPNDPVDALREHVWISPYYE
MUL_3878|M.ulcerans_Agy99 LRVASIENGSEWVHRLAKRLKKLANQHPRSFPNDPVDALREHVWISPYYE
*:..****** :*:** ***** ** * : :***: *:::***:****
Mflv_4350|M.gilvum_PYR-GCK DDVKLLAETIGVDKILFGSDWPHGEGLADPTSFTADIPQFPEFSHEDTRK
MSMEG_2230|M.smegmatis_MC2_155 DDVKLLADTIGVDKILFGSDWPHGEGLADPTSFTADIPQFPEFSHEDTRR
Mvan_1994|M.vanbaalenii_PYR-1 DDVKLLADTIGVDKILFGSDWPHGEGLADPTSFTADIPQFPEFSHEDTRK
TH_4037|M.thermoresistible__bu DDVKLLAETIGVDRILFGSDWPHGEGLADPMTFTADIPQFPEFSHEDTRK
MAV_1591|M.avium_104 DDLPELARVIGVDKILFGSDWPHGEGLASPVSFTAELKGFSES---DIRK
MMAR_4014|M.marinum_M EDLTVLADRIGVDRILFGSDWPHGEGLESPLAFTEELTGFSRA---EVQK
MUL_3878|M.ulcerans_Agy99 EDLTVLADRIGVDRILFGSDWPHGEGLESPLAFTLELTGFSRA---AVQK
:*: ** ****:************* .* :** :: *.. ::
Mflv_4350|M.gilvum_PYR-GCK VMRDNALTLVHGA--------------
MSMEG_2230|M.smegmatis_MC2_155 VMRHNALELLGDPDRTAPGARHLAASV
Mvan_1994|M.vanbaalenii_PYR-1 VMRDNALTLVGTHVSA-----------
TH_4037|M.thermoresistible__bu VMRGNALTLLGANVPATA---------
MAV_1591|M.avium_104 IMRDNALDLLGVQVGSAA---------
MMAR_4014|M.marinum_M IMRDNALDFLGVTVASAA---------
MUL_3878|M.ulcerans_Agy99 IMRDNALDFLGVTVASVA---------
:** *** ::