For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. marinum M MMAR_3558 (-)

annotation: aminotransferase (adenosylmethionine-8-amino-7- oxononanoate) BioA
coordinates: 4376577 - 4377932
length: 451

MTELSAKANRHLWGHFARHGAGITPPIITRGEGVTIWDDRGNSYLDGLSGLFVVQAGHGRTELAEAAAKQ
AETLAFFPLWSYATPTAIELAERVAHYAPGDLNRVFFTTGGGEAVESAWKLAKQYFKETGKPGKYKAISR
STAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPNTNFYRAPAPYADDSKEFGLWAANRIAEAIEFEGP
DTVAAVFLEPVQNAGGCFPPPPGYFERVREICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDIITCA
KGMTSGYSPIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVALANLDIFEREGLNDHVKQNAPAFR
TTLEKLLDLPIVGDVRGEGFFYGIELVKDKDTKATFSDEESERLLRGFLSSALLEAGLYCRADDRGDPVV
QLAPPLISGQQEFDKMEQILRGVLSEAWSRL
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. marinum MMMAR_3558--100% (451)aminotransferase (adenosylmethionine-8-amino-7- oxononanoate) BioA
M. marinum MMMAR_2465argD4e-4933.49% (439) acetylornithine aminotransferase ArgD
M. marinum MMMAR_2118gabT3e-4030.18% (444) 4-aminobutyrate aminotransferase GabT

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3362-0.080.79% (432) hypothetical protein Mb3362
M. gilvum PYR-GCKMflv_4862-0.085.78% (450) hypothetical protein Mflv_4862
M. tuberculosis H37RvRv3329-0.080.79% (432) hypothetical protein Rv3329
M. leprae Br4923MLBr_01409argD7e-4932.82% (451) acetylornithine aminotransferase
M. abscessus ATCC 19977MAB_3326c-0.086.19% (449) hypothetical protein MAB_3326c
M. avium 104MAV_4304-0.081.18% (441) hypothetical protein MAV_4304
M. smegmatis MC2 155MSMEG_1662-0.086.44% (450) hypothetical protein MSMEG_1662
M. thermoresistible (build 8)TH_1978-0.079.15% (446) PROBABLE AMINOTRANSFERASE
M. ulcerans Agy99MUL_2791-0.099.78% (451) hypothetical protein MUL_2791
M. vanbaalenii PYR-1Mvan_1570-0.085.65% (446) hypothetical protein Mvan_1570

CLUSTAL 2.0.9 multiple sequence alignment


Mb3362|M.bovis_AF2122/97            ------------------------MHFARHGAGIQHPVIVRGDGVTIFDD
Rv3329|M.tuberculosis_H37Rv         ------------------------MHFARHGAGIQHPVIVRGDGVTIFDD
MAV_4304|M.avium_104                ------------------MTDHLWLHFARHGPGITPPIITRGHGVTIYDD
MMAR_3558|M.marinum_M               -----------MTELSAKANRHLWGHFARHGAGITPPIITRGEGVTIWDD
MUL_2791|M.ulcerans_Agy99           -----------MTELSAKANRHLWGHFARHGAGITPPIITRGEGVTIWDD
Mflv_4862|M.gilvum_PYR-GCK          MTIISETEQATASELGAKANRHLWGHFARHGAGITPPIITRGEGVHIFDD
MSMEG_1662|M.smegmatis_MC2_155      -MTTADITQTAPTDLGAKANRHLWGHFARHGDGITPPIITRGEGVKIFDD
Mvan_1570|M.vanbaalenii_PYR-1       -MTTTDIAPQVSSDLEAKANRHLWGHFARHGKGITPPIITRGEGVHIWDS
MAB_3326c|M.abscessus_ATCC_199      -MTSVDVVQDLSGDLHAKSSRHLWGHFARHGAGIAPPIITRGEGVRIWDD
TH_1978|M.thermoresistible__bu      ----------MSTDRAAQADRHLWGHFARHGPGVTPPIIVRGDGVTIWDD
MLBr_01409|M.leprae_Br4923          ---------MTPTQTNTATMQQRWETVMMNNYGTPPIVLASGNGAVVTDV
                                                              .  :. *    ::. *.*. : * 

Mb3362|M.bovis_AF2122/97            RGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIE
Rv3329|M.tuberculosis_H37Rv         RGKSYLDALSGLFVVQVGYGRAELAEAAARQAGTLGYFPLWGYATPPAIE
MAV_4304|M.avium_104                RGNSYLDGLSGLFTVQVGHGRAELAEAAARQAGTLAFFPLWGYATPPAIE
MMAR_3558|M.marinum_M               RGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAFFPLWSYATPTAIE
MUL_2791|M.ulcerans_Agy99           RGNSYLDGLSGLFVVQAGHGRTELAEAAAKQAETLAFFPLWSYATPTAIE
Mflv_4862|M.gilvum_PYR-GCK          KGKRYIDGLSGLFVVQVGHGRKELAEAAAKQAEQLAFFPLWSYATPTAVE
MSMEG_1662|M.smegmatis_MC2_155      SGKSYIDGLSGLFVVQVGHGRKELAEAAAKQAEKLSFFPLWSYATPPAIE
Mvan_1570|M.vanbaalenii_PYR-1       TGRKYIDGLSGLFVVQAGHGRKELAEAAAKQAEQLAFFPLWSYATPTAIE
MAB_3326c|M.abscessus_ATCC_199      RGKSYIDGLSGLFVVQAGHGRAELAQAAARQAEKLAYFPLWSYATEPAIE
TH_1978|M.thermoresistible__bu      HGRRYLDGLSGLFVVQAGHGRAELAEAAARQAGQLAYFPLWSYATPPAIE
MLBr_01409|M.leprae_Br4923          DSNTYLDLLGGIAVNVLGHRHPAVIEAVTHQITTLGHTSNL-YATEPSIT
                                     .. *:* *.*: .   *: :  : :*.::*   *.. .   *** .:: 

Mb3362|M.bovis_AF2122/97            LAERLARYAPGDLN-RVFFTSGGTEAVETAWKVAKQYFKLTGKPGKHKVI
Rv3329|M.tuberculosis_H37Rv         LAERLARYAPGDLN-RVFFTSGGTEAVETAWKVAKQYFKLTGKPGKQKVI
MAV_4304|M.avium_104                LAERLAGYAPGDLN-RVFFTTGGTEAVETAWKLAKQYFKLTGKPGKHKVI
MMAR_3558|M.marinum_M               LAERVAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKETGKPGKYKAI
MUL_2791|M.ulcerans_Agy99           LAERVAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKETGKPGKYKAI
Mflv_4862|M.gilvum_PYR-GCK          LAERLAGYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV
MSMEG_1662|M.smegmatis_MC2_155      LAERVASFAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV
Mvan_1570|M.vanbaalenii_PYR-1       LADRLAHYAPADLN-RVFFTTGGGEAVESAWKLAKQYYKLVGKPGKFKVI
MAB_3326c|M.abscessus_ATCC_199      LADRLAGYAPGDLN-RVFFTTGGGEAVESAWKLAKQFFKLTGKPGKHKVI
TH_1978|M.thermoresistible__bu      LAERIAHYAPGDLN-RVFFTTGGGEAVESAWKLAKQYFKLTGKPGKHKVV
MLBr_01409|M.leprae_Br4923          LAEELVALLGADTQTRVFFCNSGTEANELAFKLSR-------LTGRTKLV
                                    **:.:.    .* : **** ..* ** * *:*:::        .*: * :

Mb3362|M.bovis_AF2122/97            SRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAP--LHT
Rv3329|M.tuberculosis_H37Rv         SRSIAYHGTTQGALAITGLPLFKAPFEPLTPGGFRVPNTNFYRAP--LHT
MAV_4304|M.avium_104                SRAVAYHGTTQGALAITGLPRYKAPFEPVTPGGFRVPNTNFYRAPEAFAN
MMAR_3558|M.marinum_M               SRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPNTNFYRAPAPYAD
MUL_2791|M.ulcerans_Agy99           SRSTAYHGTPHGALAITGLPAFKAPFEPLTPGGVRIPNTNFYRAPAPYAD
Mflv_4862|M.gilvum_PYR-GCK          SRSIAYHGTPQGALSITGIPAFKAPFEPLVPGGFRVPNTNFYRAPAEYAH
MSMEG_1662|M.smegmatis_MC2_155      SRSIAYHGTPQGALAITGIPAFKAPFEPLTPGGFRAPNTNFYRAPAEYAH
Mvan_1570|M.vanbaalenii_PYR-1       SRAIAYHGTPQGALAITGLPDFKKPFEPLTPGGFRVPNTNFYRAPAPYDT
MAB_3326c|M.abscessus_ATCC_199      SRAIAYHGTPQGALAITGLPAFKAPFEPLTPGGFRAPNTNFYRAPEPYAH
TH_1978|M.thermoresistible__bu      SRAVAYHGTPQGALAITGLPMFKAPFEPLTPGGFRVPNTNFYRAPAPYRD
MLBr_01409|M.leprae_Br4923          AAQAAFHGRTMGSLALTGQPAKQAAFEPLPGHVTHVPYG-----------
                                    :   *:** . *:*::** *  : .***:     : *             

Mb3362|M.bovis_AF2122/97            DLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERV
Rv3329|M.tuberculosis_H37Rv         DLKEFGRWAADRIAEAIEFEGPDTVAAVFLEPVQNAGGCIPAPPGYFERV
MAV_4304|M.avium_104                DPKGFGLWAADRIAEAIEFEGPDTVAAVFVEPVQNAGGSIPPPPGYFERV
MMAR_3558|M.marinum_M               DSKEFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
MUL_2791|M.ulcerans_Agy99           DSKDFGLWAANRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
Mflv_4862|M.gilvum_PYR-GCK          DEKAFGRYCADRIAEAIEFEGPETVAAVFLEPVQNAGGCFPPPPGYFERV
MSMEG_1662|M.smegmatis_MC2_155      DEKAFGRYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
Mvan_1570|M.vanbaalenii_PYR-1       DPKAWGRYCADRIAEAIEFEGPDTVCAVFLEPVQNAGGCFPPPPGYFERV
MAB_3326c|M.abscessus_ATCC_199      DSKAFGQYCADRIAEAIEFEGPDTVAAVFLEPVQNAGGCFPPPPGYFERV
TH_1978|M.thermoresistible__bu      DEKAFGRYCADRIAETIEFEGPDTVAAVVLEPVQNAGGCIPPPPGYFERV
MLBr_01409|M.leprae_Br4923          --------QVDALAAAVDN----DTAAVFLEPIMGESGVIVPPEGYLAAA
                                             .: :* :::      ..**.:**: . .* : .* **:  .

Mb3362|M.bovis_AF2122/97            REICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYS
Rv3329|M.tuberculosis_H37Rv         REICDRYDVLLVSDEVICAFGRIGSMFACEDLGYVPDMITCAKGLTSGYS
MAV_4304|M.avium_104                REICDRYDVLLVSDEVICAFGRIGSMFACADFGYVPDMITCAKGMTSGYS
MMAR_3558|M.marinum_M               REICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDIITCAKGMTSGYS
MUL_2791|M.ulcerans_Agy99           REICDEYDVLLVSDEVICAFGRIGSMFACNDFGYVPDIITCAKGMTSGYS
Mflv_4862|M.gilvum_PYR-GCK          REICDEYDVLLVSDEVICAYGRIGSMFACEDFGYVPDIITCAKGLTSGYS
MSMEG_1662|M.smegmatis_MC2_155      REICDEYDVLLVSDEVICAYGRIGSMFACNDFGYVPDIITSAKGLTSGYS
Mvan_1570|M.vanbaalenii_PYR-1       REICDEYDVLLVSDEVICAFGRIGSMFACDDFGYVPDIITCAKGLTSGYS
MAB_3326c|M.abscessus_ATCC_199      REICDEYDVLLVSDEVICAFGRIGSMFACEDFGYQPDIVTCAKGMTSGYS
TH_1978|M.thermoresistible__bu      REICDTYDVLLISDEVICAFGRIGSMFACDDFGYQPDIITCAKGLTSGYA
MLBr_01409|M.leprae_Br4923          RDITTRHGALLVIDEVQTGIGRTGAFFAHQHDSITPDVVTLAKGLGGG-L
                                    *:*   :..**: ***  . ** *::**  . .  **::* ***: .*  

Mb3362|M.bovis_AF2122/97            PLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGL
Rv3329|M.tuberculosis_H37Rv         PLGAMIASDRLFEPFNDGETMFAHGYTFGGHPVSAAVGLANLDIFEREGL
MAV_4304|M.avium_104                PIGAMIASERLFEPFADGDTMFPHGYTFGGHPVSAAVGLVNLDIFEREGL
MMAR_3558|M.marinum_M               PIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVALANLDIFEREGL
MUL_2791|M.ulcerans_Agy99           PIGAMVASDRLFEPFNDGKTTFAHGYTFGGHPVSSAVALANLDIFEREGL
Mflv_4862|M.gilvum_PYR-GCK          PIGAMIASDRLFEPFNDGSTVFGHGYTFGGHPVSSAVALANLDIFEREGL
MSMEG_1662|M.smegmatis_MC2_155      PLGAMVASDRLFEPFNDGKTVFGHGYTFGGHPVSAAVAMANLDIFEREGI
Mvan_1570|M.vanbaalenii_PYR-1       PIGAMIASDRLFEPFNDGKTVFGHGYTFGGHPVSSAVALANLDIFEREGL
MAB_3326c|M.abscessus_ATCC_199      PIGAMIATDRLFEPFNDGKTTFPHGYTFGGHPVSAAVALANLDIFEREGL
TH_1978|M.thermoresistible__bu      PLGAMIATDRLFEPFADGKTVFPHGYTFGGHPVSAAVALANLDIFEREGL
MLBr_01409|M.leprae_Br4923          PIGAFLATGPAAELLTLG----LHGSTFGGNPVCTAAALAVLRVLATQGL
                                    *:**::*:    * :  *     ** ****:**.:*..:. * ::  :*:

Mb3362|M.bovis_AF2122/97            SDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTD
Rv3329|M.tuberculosis_H37Rv         SDHVKRNSPALRATLEKLYDLPIVGDIRGEGYFFGIELVKDQATKQTFTD
MAV_4304|M.avium_104                NDRVRTLAPTFRATLEKLYDLPIVGDVRGEGFFYGVELVKDRATKQTFTD
MMAR_3558|M.marinum_M               NDHVKQNAPAFRTTLEKLLDLPIVGDVRGEGFFYGIELVKDKDTKATFSD
MUL_2791|M.ulcerans_Agy99           NDHVKQNAPAFRTTLEKLLDLPIVGDVRGEGFFYGIELVKDKDTKATFSD
Mflv_4862|M.gilvum_PYR-GCK          NERVKQNAPAFRATLEQLLELPIVGDVRGEGYFYGIELVKDKATKETFND
MSMEG_1662|M.smegmatis_MC2_155      NDHVKTMAPAFRATLEKLYDLPIVGDVRGEGFFYGIELVKDKTTKETFND
Mvan_1570|M.vanbaalenii_PYR-1       NAHVKDNAPVFRATLEQLLELPIVGDVRGEGFFYGIELVKDKATKETFNE
MAB_3326c|M.abscessus_ATCC_199      NDRVRENAPVFRATLEKLYDLPIVGDVRGEGYFYGIELVKDKAAKTTFSD
TH_1978|M.thermoresistible__bu      NDRVRTLSPLLRATLERLYELPIVGDVRGEGYFFAVELVQDKAGRQPFSA
MLBr_01409|M.leprae_Br4923          VRRAEVLGDSMRIGIESLS-HPLIDQVRGRGLLLGIVLTAPRAKD-----
                                      :..  .  :*  :* *   *::.::**.* : .: *.  :        

Mb3362|M.bovis_AF2122/97            DERARLLG-QVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIET
Rv3329|M.tuberculosis_H37Rv         DERARLLG-QVSAALFEAGLYCRTDDRGDPVVQVAPPLISGQPEFDTIET
MAV_4304|M.avium_104                SERRALLG-RVGAALFEAGLYCRTDDRGDSVIQLAPPLISGQAEFDTIEA
MMAR_3558|M.marinum_M               EESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAPPLISGQQEFDKMEQ
MUL_2791|M.ulcerans_Agy99           EESERLLRGFLSSALLEAGLYCRADDRGDPVVQLAPPLISGQQEFDKMEQ
Mflv_4862|M.gilvum_PYR-GCK          EESERLLRGFLTPALWDAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYD
MSMEG_1662|M.smegmatis_MC2_155      EESERLLRGFLTPALWEAGLYCRADDRGDPVVQLAPPLISGQAEFDAIYD
Mvan_1570|M.vanbaalenii_PYR-1       DESERLLRGFLTSALFEGGLYCRADDRGDPVVQLAPPLISGKKEFDAIYD
MAB_3326c|M.abscessus_ATCC_199      EESERLLRGFLSAALWDAGLYCRADDRGDPVIQLAPPLISGPREFEAIEQ
TH_1978|M.thermoresistible__bu      EESARLVA-HLNRALLDAGLYCRADNRGDTVVQVAPPLISGPAEFDAMHD
MLBr_01409|M.leprae_Br4923          ----------IEKAARDAGFLVNATAP--EVIRLAPPLIITESQIDSFIT
                                              :  *  :.*:  .:      *:::*****    ::: :  

Mb3362|M.bovis_AF2122/97            ILRSVLTDTGRKYLHL-
Rv3329|M.tuberculosis_H37Rv         ILRSVLTDTGRKYLHL-
MAV_4304|M.avium_104                ALRGVLSDECRRL----
MMAR_3558|M.marinum_M               ILRGVLSEAWSRL----
MUL_2791|M.ulcerans_Agy99           ILRGVLSEAWSRL----
Mflv_4862|M.gilvum_PYR-GCK          ILRSVLTEASARM----
MSMEG_1662|M.smegmatis_MC2_155      ILHNVLTEAGNRL----
Mvan_1570|M.vanbaalenii_PYR-1       ILHRVLSEASRML----
MAB_3326c|M.abscessus_ATCC_199      ILRGVLTEAWARL----
TH_1978|M.thermoresistible__bu      ILRTVLKDAPNHV----
MLBr_01409|M.leprae_Br4923          ALPGILDASIAELGKKA
                                     *  :*