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ALGDDGRRSVAQAQDSAHGFGHDYTVGSPHLRHATLRNNIENRITNTIKEILQQRGECAVLEIGAGHGSF TDTVLAAGGTASSTEMSKASAEYLESKFRGNSRVTVIYDPDGQAPFDQPVQYDVILLISVIHHIPDYIDV VSRLCDTVLRPGGAVVTYQDPLWYPRQKRWKRALNWGFYFLWRVTQGELRRGIATRWRRLRGVYSHSNPS DLVEYHVVRQGVDELALQDIFSARFASVELSTYFSTQSPQLQSIGQRCLPPNNFGFVARGRLG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1700 | - | - | 100% (274) | methyltransferase type 12 |
| M. vanbaalenii PYR-1 | Mvan_3149 | - | 2e-05 | 26.36% (110) | methyltransferase type 12 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2978c | - | 4e-07 | 32.61% (92) | hypothetical protein Mb2978c |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2954c | - | 4e-07 | 32.61% (92) | hypothetical protein Rv2954c |
| M. leprae Br4923 | MLBr_01723 | - | 6e-05 | 27.57% (214) | hypothetical protein MLBr_01723 |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_4513 | - | 4e-05 | 23.64% (110) | hypothetical protein MMAR_4513 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4684 | - | 2e-05 | 25.45% (110) | hypothetical protein MUL_4684 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4513|M.marinum_M -----------------------MGRVALTESDEYARQY---------FD
MUL_4684|M.ulcerans_Agy99 -----------------------MGRVALTESEEYARQY---------FD
Mb2978c|M.bovis_AF2122/97 --------------------MRLPGMLRPTAERHFHSIF---------YL
Rv2954c|M.tuberculosis_H37Rv --------------------MRLPGMLRPTAERHFHSIF---------YL
Mvan_1700|M.vanbaalenii_PYR-1 ------------------MALGDDGRRSVAQAQDSAHGFGHDYTVGSPHL
MLBr_01723|M.leprae_Br4923 MTRSTEISANAVPNPHATAEQVAAARKDSKLAQVLYHDWEAENYDEKWSI
. :
MMAR_4513|M.marinum_M EQAESNKEYWRRFGV-------VPDWAGKRVLDVGCGHGALSIDIAQAGA
MUL_4684|M.ulcerans_Agy99 EQAESNNEYWRRFGV-------VPDWAGKRVLDVGCGHGALSIDIAQAGA
Mb2978c|M.bovis_AF2122/97 RHNARRQEHLATLG---------LDLGNKSVLEVGAGIGDHTQFFLDRGC
Rv2954c|M.tuberculosis_H37Rv RHNARRQEHLATLG---------LDLGNKSVLEVGAGIGDHTQFFLDRGC
Mvan_1700|M.vanbaalenii_PYR-1 RHATLRNNIENRITNTIK--EILQQRGECAVLEIGAGHGSFTDTVLAAGG
MLBr_01723|M.leprae_Br4923 SYDQRCVDYVRHCFDAIVPDELFTELPYDCALELGCGTGFFLLNLIQSGV
: : .*::*.* * . *
MMAR_4513|M.marinum_M SVLG--VDLDEGRVAFANRNLAQRFPELADRVRFR---AVDVRSLPVDEP
MUL_4684|M.ulcerans_Agy99 SVLG--VDLDEGRVAFANRNLAQRFPEQADRVRFR---AVDVRSLPVDEP
Mb2978c|M.bovis_AF2122/97 KVLC--TEPRGENLDVIRQRFGSNPNVTVDHLDLDGDLPAEAHQYDVVYC
Rv2954c|M.tuberculosis_H37Rv KVLC--TEPRGENLDVIRQRFGSNPNVTVDHLDLDGDLPAEAHQYDVVYC
Mvan_1700|M.vanbaalenii_PYR-1 TASS--TEMSKASAEYLESKFRGNSRVTVIYDPDGQAPFDQPVQYDVILL
MLBr_01723|M.leprae_Br4923 ARRGSVTDLSPGMVKIATRNGQSLGLDINGRVADAEGIPYDDNTFDLVVG
.: . : :
MMAR_4513|M.marinum_M FDVIVSK----DTFEHVADVAT----LLRALGERLTRPGGRIYAGFSPLY
MUL_4684|M.ulcerans_Agy99 FDVIVSK----DTFEHVADVAS----LLLALGERLTRPGGRIYAGFSPLY
Mb2978c|M.bovis_AF2122/97 YGVLYHLSRPAEALAWMCDRAV----DLLLLETCVSYSGEDEPFLVSERA
Rv2954c|M.tuberculosis_H37Rv YGVLYHLSRPAEALAWMCDRAV----DLLLLETCVSYSGEDEPFLVSERA
Mvan_1700|M.vanbaalenii_PYR-1 ISVIHHIPDYIDVVSRLCDTVLRPGGAVVTYQDPLWYPRQKRWKRALNWG
MLBr_01723|M.leprae_Br4923 HAVLHHIP---DVELSLREVLR-----VLKPGGRFVFAGEP--TDVGNRY
*: :. : : : . .
MMAR_4513|M.marinum_M YSPFGDHGRTGLKVPWAHAILPKRLVFAAAARKYGHPVGSLLDIGLNGNT
MUL_4684|M.ulcerans_Agy99 YSPFGDHGRTGLKVPWTHAILPKRLVFAVAARKYGHPVGSLLDIGLNGNT
Mb2978c|M.bovis_AF2122/97 SSPSQAITGTGCRPSRVWVMNRLREKMPHVYVTATQPRHRQFPLDWRANG
Rv2954c|M.tuberculosis_H37Rv SSPSQAITGTGCRPSRVWVMNRLREKMPHVYVTATQPRHRQFPLDWRANG
Mvan_1700|M.vanbaalenii_PYR-1 FYFLWRVTQGELRRG----IATRWRRLRGVYSHSNPSDLVEYHVVRQGVD
MLBr_01723|M.leprae_Br4923 ARVFADLTWKVTIRVVQLPGLSAWRRTQVEIDENSRAAALEWVVDLHTFE
. : .
MMAR_4513|M.marinum_M PDQFRAAFDNSGLRQLDIGYNRGAKRLL----------------------
MUL_4684|M.ulcerans_Agy99 PDQFRAAFDNSGLRQLDIGYNRGAKRLL----------------------
Mb2978c|M.bovis_AF2122/97 P------IASTGLARAVFVASRAPLNLP----------------------
Rv2954c|M.tuberculosis_H37Rv P------IASTGLARAVFVASRAPLNLP----------------------
Mvan_1700|M.vanbaalenii_PYR-1 E------LALQDIFSARFASVELSTYFS----------------------
MLBr_01723|M.leprae_Br4923 PKVLETMATNAGAVQVKTVTEEFTAAMLGWPLRTFESTMPPSKLGWGWAR
. . . :
MMAR_4513|M.marinum_M -------PALERARRHWRRFDRFTTVSIYAVFGV---
MUL_4684|M.ulcerans_Agy99 -------PALERARRHWRRFDRFTTVSIYAVFGV---
Mb2978c|M.bovis_AF2122/97 -------TLVEELPMVQRRC-----------------
Rv2954c|M.tuberculosis_H37Rv -------TLVEELPMVQRRC-----------------
Mvan_1700|M.vanbaalenii_PYR-1 -------TQSPQLQSIGQRCLPPNNFGFVARGRLG--
MLBr_01723|M.leprae_Br4923 FAFTSWKTLSWVDANVWRRVIPKSWFYNIIITGVKPS
. :*