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AGPRRRLSPDERRSELLTLGAEVFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAETERL FHATNTPPQPGQTLFAQVRAGVLAYLQYDEHHPHGAWAAYLGMGRSDPLLRGIEDIDNDRQANRIIDRIT TAVGGGIDSKLERDLRATVYGWLAFTFEMCRQRLMDASLDADFIAGLCAHGLMDAVGRVPGIPAALAEAV AVDRR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1640 | - | - | 100% (216) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1795 | - | 1e-11 | 35.00% (100) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4778 | - | 4e-10 | 33.01% (103) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3323 | - | 4e-78 | 62.73% (220) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4802 | - | 1e-102 | 83.80% (216) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3295 | - | 4e-78 | 62.73% (220) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 9e-77 | 63.64% (220) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3650 | - | 5e-49 | 44.19% (215) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1239 | - | 1e-75 | 61.82% (220) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4266 | - | 3e-73 | 60.55% (218) | hypothetical protein MAV_4266 |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 7e-12 | 28.65% (185) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 3e-12 | 36.00% (100) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2648 | - | 8e-76 | 61.82% (220) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1640|M.vanbaalenii_PYR-1 -------------------------MAGPRR--RLSPDERRSELLTLGAE
Mflv_4802|M.gilvum_PYR-GCK -------------------------MAEARR--RLSPDDRRNELLALGAE
MMAR_1239|M.marinum_M -------------------------MATARR--RLSPEDRRAELLALGAE
MUL_2648|M.ulcerans_Agy99 -------------------------MATARR--RLSPEDRRAELLALGAE
Mb3323|M.bovis_AF2122/97 -------------------------MATARR--RLSPQDRRAELLALGAE
Rv3295|M.tuberculosis_H37Rv -------------------------MATARR--RLSPQDRRAELLALGAE
MLBr_00717|M.leprae_Br4923 -------------------------MTTARR--RLSPEDRRAELLALGAE
MAV_4266|M.avium_104 -------------------------MATARR--RLSPEDRRAELLALGAE
MAB_3650|M.abscessus_ATCC_1997 --------------MTDDSDAVRPSGASPRR--RLTPEDRRAELLDFGTQ
MSMEG_1935|M.smegmatis_MC2_155 MSDLANTAERRGEKRP---------AGGNRRGNRLPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
** **. ::** :** .::
Mvan_1640|M.vanbaalenii_PYR-1 VFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAETERLFH
Mflv_4802|M.gilvum_PYR-GCK VFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAESERLFD
MMAR_1239|M.marinum_M VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
MUL_2648|M.ulcerans_Agy99 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
Mb3323|M.bovis_AF2122/97 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
Rv3295|M.tuberculosis_H37Rv VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
MLBr_00717|M.leprae_Br4923 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
MAV_4266|M.avium_104 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
MAB_3650|M.abscessus_ATCC_1997 LFGERHYDDVRMDEVAEQAGVSRALLYRYFPDKRAFYTAVMQAEYDRLYD
MSMEG_1935|M.smegmatis_MC2_155 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
:* .* *. . :**:*::****:.::*::*..* :: **:: . :.*
Mvan_1640|M.vanbaalenii_PYR-1 ATN-TPPQPGQTLFAQVRAGVLAYLQYDEHHPHGAWAAYLGMGRSDPLLR
Mflv_4802|M.gilvum_PYR-GCK ATN-TPAQPGQTLFTQVRAGVLAYLRYDELHPHGAWAAYMGMSRSDPVLR
MMAR_1239|M.marinum_M ATS-IESPVGMTMFEEIRLGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
MUL_2648|M.ulcerans_Agy99 ATS-IESPVGMTMFEEIRLGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
Mb3323|M.bovis_AF2122/97 ATN-KAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
Rv3295|M.tuberculosis_H37Rv ATN-KAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
MLBr_00717|M.leprae_Br4923 ATN-IPPPAGLTMFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLL
MAV_4266|M.avium_104 NTN-MDDVTGLTMYEEIRVGVLAYMAYHEQNPEAAWAAYVGLGRSDPVLL
MAB_3650|M.abscessus_ATCC_1997 ATISLDMDQTLSGFERLRRTLLVYLHYQEEHPFAPVTVFRMIDSADPTVM
MSMEG_1935|M.smegmatis_MC2_155 GVR-QALRTTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFENDYVTEPQVA
TH_0452|M.thermoresistible__bu GVR-QALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVA
. .:* : .:: : : . . : ::* :
Mvan_1640|M.vanbaalenii_PYR-1 GIEDIDNDRQANRIIDRITTAVGGG-----IDSKLERD-LRATVYGWLAF
Mflv_4802|M.gilvum_PYR-GCK GIDDHDNDRQANRIIDRVTAGVEP------LDAKVERD-LRAAVYGWLAF
MMAR_1239|M.marinum_M GIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERD-LRVIIYGWLAF
MUL_2648|M.ulcerans_Agy99 GIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERD-LRVIIYGWLAF
Mb3323|M.bovis_AF2122/97 GIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAF
Rv3295|M.tuberculosis_H37Rv GIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAF
MLBr_00717|M.leprae_Br4923 GIDDEAKNRQMEHIMSRIGDVVSVVP-ESKLHPDIERD-LRVIVHGWLAF
MAV_4266|M.avium_104 GVEDDAKNRQMEHIMSRINQLLAEVP--ATLEPDVERH-LRVILHGWLAF
MAB_3650|M.abscessus_ATCC_1997 AIEQQEYDKQTDRIMAVVDHVAGD-----EMTPALVTD-LKVVIRAWLAF
MSMEG_1935|M.smegmatis_MC2_155 AQVKVATEACTDAVFDLISR-----------DSGLEAHRARMIAVGLVAI
TH_0452|M.thermoresistible__bu AQVKVATEACTDAVFDLISQ-----------DSGLEAHRARMIAVGLVAI
. . : : :: : : . : . :*:
Mvan_1640|M.vanbaalenii_PYR-1 TFEMCRQRLMDAS-LDADFIAGLCAHGLMDAVGRVPGIPAALAEAVAVDR
Mflv_4802|M.gilvum_PYR-GCK TFEMCRQRLMDAS-LDADYLGDLCAHALMDALARVPGIPADLAEAVAPDR
MMAR_1239|M.marinum_M TFEICRQRIMDPG-TDADRLADACAHTLLDSIARVPEIPGELAEAMATAR
MUL_2648|M.ulcerans_Agy99 TFEICRQRIMDPG-TDADRLADACAHTLLDSIARVPEIPGELAEAMATAR
Mb3323|M.bovis_AF2122/97 TFELCRQRIMDPS-TDAERLADACAHALLDAISRLPQIPAELADAMATAR
Rv3295|M.tuberculosis_H37Rv TFELCRQRIMDPS-TDAERLADACAHALLDAISRLPQIPAELADAMATAR
MLBr_00717|M.leprae_Br4923 TFEVCRQRIMDPS-TDADRLADSCAHALLDAIARVPEISKELADAMAIAR
MAV_4266|M.avium_104 TFEICRQRIIDPT-TDADKLADACAHALLDAIGRVPEIPEELGEAMANSR
MAB_3650|M.abscessus_ATCC_1997 NQELARQRALNPE-LDVDWLADTSAHAMIDAVRRMPNIPQAVVDLMGAD-
MSMEG_1935|M.smegmatis_MC2_155 SVDSARYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS----------
TH_0452|M.thermoresistible__bu SVDCARYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS----------
. : .* . : .: ..: ::*
Mvan_1640|M.vanbaalenii_PYR-1 R---
Mflv_4802|M.gilvum_PYR-GCK R---
MMAR_1239|M.marinum_M HTPQ
MUL_2648|M.ulcerans_Agy99 HTPQ
Mb3323|M.bovis_AF2122/97 M---
Rv3295|M.tuberculosis_H37Rv M---
MLBr_00717|M.leprae_Br4923 QPPQ
MAV_4266|M.avium_104 L---
MAB_3650|M.abscessus_ATCC_1997 ----
MSMEG_1935|M.smegmatis_MC2_155 ----
TH_0452|M.thermoresistible__bu ----