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VILTTINVNGIRAAVKQRSVENLGLLAWFKETASDVVCLQETRADDEQLGEALAPVLADGWHLASAAPHV KGRNGVAVLSRSPFDDVRIGCGAEEFAAHGRYIEVDTAGVTVGSVYVPTGEAETDRQLEKERFMAAVAAR MAVLLARSVEDGRHAVLSGDWNIAHTENDIKNWKGNVKKAGFLPQERQWLTELLGTGWVDVVRQAHPDVA GPYAWWSWRGKAFDNDAGWRIDYQLATPGLAGRVAAVTTERPAAYALRWSDHCPVTVHYA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1556 | - | - | 100% (270) | exodeoxyribonuclease III Xth |
| M. vanbaalenii PYR-1 | Mvan_0730 | - | 1e-20 | 29.29% (280) | exodeoxyribonuclease III Xth |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0435c | xthA | 3e-21 | 30.85% (282) | exodeoxyribonuclease III protein |
| M. gilvum PYR-GCK | Mflv_4873 | - | 1e-140 | 86.30% (270) | exodeoxyribonuclease III Xth |
| M. tuberculosis H37Rv | Rv0427c | xthA | 3e-21 | 30.85% (282) | exodeoxyribonuclease III protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3684c | - | 2e-97 | 63.47% (271) | putative exodeoxyribonuclease |
| M. marinum M | MMAR_0742 | xthA | 3e-22 | 30.55% (275) | exodeoxyribonuclease III protein XthA |
| M. avium 104 | MAV_4727 | xth | 1e-23 | 31.77% (277) | exodeoxyribonuclease III |
| M. smegmatis MC2 155 | MSMEG_1656 | xth | 1e-116 | 72.01% (268) | exodeoxyribonuclease III |
| M. thermoresistible (build 8) | TH_1973 | xth | 1e-111 | 70.85% (271) | exodeoxyribonuclease III |
| M. ulcerans Agy99 | MUL_1374 | xthA | 1e-20 | 30.00% (270) | exodeoxyribonuclease III protein XthA |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1556|M.vanbaalenii_PYR-1 -----------------------MILTTINVNGIRAAVKQRSVENLGLLA
Mflv_4873|M.gilvum_PYR-GCK -------------------MTRPVTVSTINVNGIRAAIKQRSPENLGMLP
MSMEG_1656|M.smegmatis_MC2_155 -----------------MASPQTLTVTTINVNGARAACKERSTENLGMLA
TH_1973|M.thermoresistible__bu --------------------MSRLIVTTINVNGIRAAVRRRSESNLGLLA
MAB_3684c|M.abscessus_ATCC_199 ------------------MSAQKITVTTINVNGIRAAVKERSAENRGLLP
Mb0435c|M.bovis_AF2122/97 MPDGTIDGGHPQRPASPRLRSPLLRLATWNVNSIRTRLDR-------VLD
Rv0427c|M.tuberculosis_H37Rv MPDGTIDGGHPQRPASPRLRSPLLRLATWNVNSIRTRLDR-------VLD
MMAR_0742|M.marinum_M MPDGTLR------------------LATWNVNSIRTRLPR-------VLD
MUL_1374|M.ulcerans_Agy99 ------------------------------MNSIRTRLPR-------VLD
MAV_4727|M.avium_104 -----------------------MRLATWNVNSIRSRLPR-------VLD
:*. *: . :*
Mvan_1556|M.vanbaalenii_PYR-1 WFKETASDVVCLQETRADDEQLGEALAPVLADGWHLASAAPHVKGRNGVA
Mflv_4873|M.gilvum_PYR-GCK WFKETAADVVCLQETRADDAQLAEALAPVLADGWHLASAEPSMKGRNGVA
MSMEG_1656|M.smegmatis_MC2_155 WLKQTRADVICMQETRCEDDQLAATFETAFADGWHLASAPSERKGRNGVA
TH_1973|M.thermoresistible__bu WLDDTAADVVCLQETRCDDDQLAAALAPALDDGWQLVSACPHLKGRNGVA
MAB_3684c|M.abscessus_ATCC_199 WLEQTSSDIVCLQEVRAEEDQLREALAPALAAGWQVVSAASSVKGRSGVG
Mb0435c|M.bovis_AF2122/97 WLGRADVDVLAMQETKCPDGQFPA--LPLFELGYDVAHVG--FDQWNGVA
Rv0427c|M.tuberculosis_H37Rv WLGRADVDVLAMQETKCPDGQFPA--LPLFELGYDVAHVG--FDQWNGVA
MMAR_0742|M.marinum_M WLERADVDVLAIQETKCSDTQFPA--LPLFELGYEVAHVG--FNQWNGVA
MUL_1374|M.ulcerans_Agy99 WLERADVDVLAIQETKCSDTQFPA--LPLFELGYEVAHVG--FNQWNGVA
MAV_4727|M.avium_104 WLARTDVDVLAMQETKCADGQFPT--LPFFELGYEVAHVG--FNQWNGVA
*: : *::.:**.:. : *: . : *:.:. . . .**.
Mvan_1556|M.vanbaalenii_PYR-1 VLSRSPFDDVRIGCGA---------EEFAAHGRYIEVDTAGVTVGSVYVP
Mflv_4873|M.gilvum_PYR-GCK VLSRDPIDEFRIGCGA---------EEFATHGRYLEADTAGVTVASVYFP
MSMEG_1656|M.smegmatis_MC2_155 VLSRTPFDDIRIGCGA---------EEFDTHGRWIEVDTAGITVVSVYVP
TH_1973|M.thermoresistible__bu VLSRRPIAAVRIGFDER--------CEFALHGRYLEADIDGVTVASVYVQ
MAB_3684c|M.abscessus_ATCC_199 ILSRVPAASTRVALDADG-------GEFDESGRYLEAEIGDLTVASIYLP
Mb0435c|M.bovis_AF2122/97 IASRVGLDDVRVGFDGQPSWSGKPEVAATTEARALGATCGGIRVWSLYVP
Rv0427c|M.tuberculosis_H37Rv IASRVGLDDVRVGFDGQPSWSGKPEVAATTEARALGATCGGIRVWSLYVP
MMAR_0742|M.marinum_M IASRVGIDDVQIGFDGQPAWSGKPEVAAAAEARAVGATCGGVRVWSLYVP
MUL_1374|M.ulcerans_Agy99 IASRVGIDDVQISFDGQPAWSGKPEVAAAAEARAVGATCGGVRVWSLYVP
MAV_4727|M.avium_104 IASRVGLDDVRVGFEGQPSWSGKPEVAAAAEARALAATCAGVRIWSLYVP
: ** ::. .* : . .: : *:*.
Mvan_1556|M.vanbaalenii_PYR-1 TGEAETD-RQLEKERFMAAVAARMAVLLARSVEDGRHAVLSGDWNIAHTE
Mflv_4873|M.gilvum_PYR-GCK TGEAETD-RQREKERFMAAVAARMAALLQRSVVDGHESVLCGDWNIAHTE
MSMEG_1656|M.smegmatis_MC2_155 TGEAETE-RQLEKERFMAGVSKRMAQLQAG----DREALVCGDWNIGHTE
TH_1973|M.thermoresistible__bu TGEAGTE-RQDEKERFMAALAHRMAALNTP----GREAVVCGDWNIAHTE
MAB_3684c|M.abscessus_ATCC_199 TGEAGTA-RQEEKERFMAAVGARMAVLAAS----GRDTVICGDWNIGHTE
Mb0435c|M.bovis_AF2122/97 NGRALDDPHYTYKLDWLAALRDTAEGWLRDD--PAAPIALMGDWNIAPTD
Rv0427c|M.tuberculosis_H37Rv NGRALDDPHYTYKLDWLAALRDTAEGWLRDD--PAAPIALMGDWNIAPTD
MMAR_0742|M.marinum_M NGRALEDPHYTYKLDWLAALRDTAQCWLKND--PGAPIALAGDFNIAPTD
MUL_1374|M.ulcerans_Agy99 NGRALEDPHYTYKLDWLAALRDTAQCWLKND--PGAPIALAGDFNIAPTD
MAV_4727|M.avium_104 NGRAVGDPHYAYKLDWLAALRDSAAGWLRED--PAAQIALAGDWNIAPQD
.*.* : * ::*.: : **:**. :
Mvan_1556|M.vanbaalenii_PYR-1 NDIKNWKGNVKKAGFLPQERQWLTELLGTGWVDVVRQAHPDVAGPYAWWS
Mflv_4873|M.gilvum_PYR-GCK NDIKNWKGNVKKAGFLPQERQWLTEVLGTGWVDVVRQAHPDVAGPYAWWS
MSMEG_1656|M.smegmatis_MC2_155 NDIKNWKGNVKKSGFLPEERAWVSGLLASGWVDAVRQLHGDVPGPYSWWS
TH_1973|M.thermoresistible__bu NDIKNWRGNLRKSGFLPNERQWVSDLLATGWVDVMRALHPDVAGPYSWWS
MAB_3684c|M.abscessus_ATCC_199 RDIKAWKANQKKAGFLPEERAWVGSLLEAGWVDSFRLLHPDVDGPYSWWS
Mb0435c|M.bovis_AF2122/97 DDVWSTEFFAGCTHVSEPERKAFNAIVDAQFTDVVRPFTP-GPGVYTYWD
Rv0427c|M.tuberculosis_H37Rv DDVWSTEFFAGCTHVSEPERKAFNAIVDAQFTDVVRPFTP-GPGVYTYWD
MMAR_0742|M.marinum_M EDVWSTEFFTGATHVSEPERKAFNAIVDAQFTDLVRPFTP-GPGVYTYWD
MUL_1374|M.ulcerans_Agy99 EDVWNTEFFTGATRVSEPERKAFNAIVDAQFTDLVRPFTP-GPGVYTYWY
MAV_4727|M.avium_104 DDVWSMEFFAGATHVSEPERRAFNAILDAQFADLVRPFAP-GPGVYTYWD
*: . : . ** . :: : :.* .* * *::*
Mvan_1556|M.vanbaalenii_PYR-1 WRGKAFDNDAGWRIDYQLATPGLAGRVAAVTTERPAAYALRWSDHCPVTV
Mflv_4873|M.gilvum_PYR-GCK WRGKAFDNDAGWRIDYHLATPGLAARATSVLTERPAAYALRWSDHCPVTV
MSMEG_1656|M.smegmatis_MC2_155 WRGKAFDNDAGWRIDYHLVTPGLAGRLVAGGTERPEAYALRWSDHAPVTV
TH_1973|M.thermoresistible__bu WRGRAFDNDAGWRIDYHLATPALAARATAARVEKPAAYDLRWSDHAPVTV
MAB_3684c|M.abscessus_ATCC_199 WRGKAFDNDAGWRIDYHLATADLGRRAHSARVERADAYALRWSDHAPVTV
Mb0435c|M.bovis_AF2122/97 YTQLRFPKKQGMRIDFILGSPALAARVMDAQIVREERKGKAPSDHAPVLV
Rv0427c|M.tuberculosis_H37Rv YTQLRFPKKQGMRIDFILGSPALAARVMDAQIVREERKGKAPSDHAPVLV
MMAR_0742|M.marinum_M YTQLRFPKKQGMRIDFILGSPALAGRVVDAQIVRDERKGKAPSDHAPVFV
MUL_1374|M.ulcerans_Agy99 YTQLRFPKKQGMRIDFILGSPALAGRVVDAQIVRDERKGKAPSDHAPVFV
MAV_4727|M.avium_104 YTALRFPKRQGMRIDFILGSPALARRVTHAQIDREERKGKGASDHAPVLV
: * : * ***: * :. *. * : ***.** *
Mvan_1556|M.vanbaalenii_PYR-1 HYA------
Mflv_4873|M.gilvum_PYR-GCK HYA------
MSMEG_1656|M.smegmatis_MC2_155 EFSA-----
TH_1973|M.thermoresistible__bu EFA------
MAB_3684c|M.abscessus_ATCC_199 EYR------
Mb0435c|M.bovis_AF2122/97 DLHAG----
Rv0427c|M.tuberculosis_H37Rv DLHAG----
MMAR_0742|M.marinum_M DLRPGPAA-
MUL_1374|M.ulcerans_Agy99 DLRPGPAA-
MAV_4727|M.avium_104 DVSRGEPPS
.