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RLATWNVNSIRARVDRVTDWLERADVDVLAMQETKCSDDQFPTMPFAALGYEIVHCGFNQWNGVAIASRV GIDDVEVGFDGQPTWNDKPEVEAAAEARALGATCGGVRVWSLYVPNGRTVDSPHYVYKLEWLAALRDTAS SWLESNPSAPIALVGDWNIAPIDDDVWDISLFQDSTHVTEPERAAFNAVVDAGFTDVVRPFTPGPGTFTY WDYTQLRFPKNRGMRIDFILGSPALAERVVHAEIARDERKTGKNRVGSPSDHAPVVVDLCD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0730 | - | - | 100% (272) | exodeoxyribonuclease III Xth |
| M. vanbaalenii PYR-1 | Mvan_1556 | - | 1e-20 | 29.29% (280) | exodeoxyribonuclease III Xth |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0435c | xthA | 1e-123 | 75.19% (270) | exodeoxyribonuclease III protein |
| M. gilvum PYR-GCK | Mflv_0177 | - | 1e-148 | 89.26% (270) | exodeoxyribonuclease III Xth |
| M. tuberculosis H37Rv | Rv0427c | xthA | 1e-123 | 75.19% (270) | exodeoxyribonuclease III protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_4189 | - | 1e-114 | 70.37% (270) | exodeoxyribonuclease III protein XthA |
| M. marinum M | MMAR_0742 | xthA | 1e-123 | 75.93% (270) | exodeoxyribonuclease III protein XthA |
| M. avium 104 | MAV_4727 | xth | 1e-118 | 72.59% (270) | exodeoxyribonuclease III |
| M. smegmatis MC2 155 | MSMEG_0829 | xth | 1e-121 | 76.67% (270) | exodeoxyribonuclease III |
| M. thermoresistible (build 8) | TH_0019 | xthA | 1e-130 | 83.20% (256) | PROBABLE EXODEOXYRIBONUCLEASE III PROTEIN XTHA (EXONUCLEASE |
| M. ulcerans Agy99 | MUL_1374 | xthA | 1e-116 | 74.52% (263) | exodeoxyribonuclease III protein XthA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0435c|M.bovis_AF2122/97 MPDGTIDGGHPQRPASPRLRSPLLRLATWNVNSIRTRLDRVLDWLGRADV
Rv0427c|M.tuberculosis_H37Rv MPDGTIDGGHPQRPASPRLRSPLLRLATWNVNSIRTRLDRVLDWLGRADV
MMAR_0742|M.marinum_M MPDGTLR------------------LATWNVNSIRTRLPRVLDWLERADV
MUL_1374|M.ulcerans_Agy99 ------------------------------MNSIRTRLPRVLDWLERADV
MAV_4727|M.avium_104 -----------------------MRLATWNVNSIRSRLPRVLDWLARTDV
Mvan_0730|M.vanbaalenii_PYR-1 -----------------------MRLATWNVNSIRARVDRVTDWLERADV
Mflv_0177|M.gilvum_PYR-GCK -----------------------MRLATWNVNSIRARVDRVTDWLERADV
TH_0019|M.thermoresistible__bu -------------------------------------VERVTDWLQRADI
MSMEG_0829|M.smegmatis_MC2_155 -----------------------MRVATWNVNSIRARVDRVTDWLARADV
MAB_4189|M.abscessus_ATCC_1997 -----------------------MRLATWNVNSIRARADRVISWLERSGT
** .** *:.
Mb0435c|M.bovis_AF2122/97 DVLAMQETKCPDGQFPALPLFELGYDVAHVGFDQWNGVAIASRVGLDDVR
Rv0427c|M.tuberculosis_H37Rv DVLAMQETKCPDGQFPALPLFELGYDVAHVGFDQWNGVAIASRVGLDDVR
MMAR_0742|M.marinum_M DVLAIQETKCSDTQFPALPLFELGYEVAHVGFNQWNGVAIASRVGIDDVQ
MUL_1374|M.ulcerans_Agy99 DVLAIQETKCSDTQFPALPLFELGYEVAHVGFNQWNGVAIASRVGIDDVQ
MAV_4727|M.avium_104 DVLAMQETKCADGQFPTLPFFELGYEVAHVGFNQWNGVAIASRVGLDDVR
Mvan_0730|M.vanbaalenii_PYR-1 DVLAMQETKCSDDQFPTMPFAALGYEIVHCGFNQWNGVAIASRVGIDDVE
Mflv_0177|M.gilvum_PYR-GCK DVLAMQETKCSDEQFPTMPFAALGYDVVHCGFSQWNGVAIASRVGIDAVE
TH_0019|M.thermoresistible__bu DVLAMQETKCADDQFPTMPFAALGYEVVHCGFNQWNGVAIASRVGIEDVE
MSMEG_0829|M.smegmatis_MC2_155 DVLAMQETKCSDDKFPAMPFVELGYEVAYHGLNQWNGVAIASRVGLENVQ
MAB_4189|M.abscessus_ATCC_1997 DVLAMQETKCSDKQFPMQAFTDAGYEVAHVGFSQWNGVAIASRVGLEDVT
****:*****.* :** .: **::.: *:.************:: *
Mb0435c|M.bovis_AF2122/97 VGFDGQPSWSGKPEVAATTEARALGATCGGIRVWSLYVPNGRALDDPHYT
Rv0427c|M.tuberculosis_H37Rv VGFDGQPSWSGKPEVAATTEARALGATCGGIRVWSLYVPNGRALDDPHYT
MMAR_0742|M.marinum_M IGFDGQPAWSGKPEVAAAAEARAVGATCGGVRVWSLYVPNGRALEDPHYT
MUL_1374|M.ulcerans_Agy99 ISFDGQPAWSGKPEVAAAAEARAVGATCGGVRVWSLYVPNGRALEDPHYT
MAV_4727|M.avium_104 VGFEGQPSWSGKPEVAAAAEARALAATCAGVRIWSLYVPNGRAVGDPHYA
Mvan_0730|M.vanbaalenii_PYR-1 VGFDGQPTWNDKPEVEAAAEARALGATCGGVRVWSLYVPNGRTVDSPHYV
Mflv_0177|M.gilvum_PYR-GCK VGFEGQPTWSDKPEAEAAAEARALGATCGGVRVWSLYVPNGRSIDSPHYT
TH_0019|M.thermoresistible__bu VGFDGQPTWSDSPDAEAAAEARALGATCNGVRVWSLYVPNGRTVGSPHYH
MSMEG_0829|M.smegmatis_MC2_155 LGFDNQPAW------EAAAEARALAATCGGVRVWSLYVPNGRTVDSPHYA
MAB_4189|M.abscessus_ATCC_1997 VGFEGQPGWSSSEDIEEASEARALGATCNGVRVWSLYVPNGRTLEDPHYQ
:.*:.** * ::****:.*** *:*:*********:: .***
Mb0435c|M.bovis_AF2122/97 YKLDWLAALRDTAEGWLRDDPAAPIALMGDWNIAPTDDDVWSTEFFAGCT
Rv0427c|M.tuberculosis_H37Rv YKLDWLAALRDTAEGWLRDDPAAPIALMGDWNIAPTDDDVWSTEFFAGCT
MMAR_0742|M.marinum_M YKLDWLAALRDTAQCWLKNDPGAPIALAGDFNIAPTDEDVWSTEFFTGAT
MUL_1374|M.ulcerans_Agy99 YKLDWLAALRDTAQCWLKNDPGAPIALAGDFNIAPTDEDVWNTEFFTGAT
MAV_4727|M.avium_104 YKLDWLAALRDSAAGWLREDPAAQIALAGDWNIAPQDDDVWSMEFFAGAT
Mvan_0730|M.vanbaalenii_PYR-1 YKLEWLAALRDTASSWLESNPSAPIALVGDWNIAPIDDDVWDISLFQDST
Mflv_0177|M.gilvum_PYR-GCK YKLKWLAALHNTAQGWLADDPSTPVALVGDWNIAPVDDDVWDISLFSEST
TH_0019|M.thermoresistible__bu YKLEWLGALRDTASKWLAADPAAQIALTGDWNIAPTDEDVWDIESYRDST
MSMEG_0829|M.smegmatis_MC2_155 YKLEWLAALRDNAQKWLADDPQAQIALTGDWNIAPTDEDVWDIDFFAGST
MAB_4189|M.abscessus_ATCC_1997 YKLRWLSALRDTAAGWLADAPDQQVALVGDWNIAPTDDDIWSVEAYQGST
*** **.**::.* ** * :** **:**** *:*:*. . : .*
Mb0435c|M.bovis_AF2122/97 HVSEPERKAFNAIVDAQFTDVVRPFTPGPGVYTYWDYTQLRFPKKQGMRI
Rv0427c|M.tuberculosis_H37Rv HVSEPERKAFNAIVDAQFTDVVRPFTPGPGVYTYWDYTQLRFPKKQGMRI
MMAR_0742|M.marinum_M HVSEPERKAFNAIVDAQFTDLVRPFTPGPGVYTYWDYTQLRFPKKQGMRI
MUL_1374|M.ulcerans_Agy99 RVSEPERKAFNAIVDAQFTDLVRPFTPGPGVYTYWYYTQLRFPKKQGMRI
MAV_4727|M.avium_104 HVSEPERRAFNAILDAQFADLVRPFAPGPGVYTYWDYTALRFPKRQGMRI
Mvan_0730|M.vanbaalenii_PYR-1 HVTEPERAAFNAVVDAGFTDVVRPFTPGPGTFTYWDYTQLRFPKNRGMRI
Mflv_0177|M.gilvum_PYR-GCK HVTAPERAAFNAIVDAGFTDVVRPFTPGPGTFTYWDYTQLRFPKNRGMRI
TH_0019|M.thermoresistible__bu HVTEPERAAFRAVVDAGYIDVVRPFTPGPGVYTYWDYTQLRFPKNRGMRI
MSMEG_0829|M.smegmatis_MC2_155 HVTEKERAAFQAIVDAQFADVVRPFAPGPGVYTYWDYTQLRFPKRQGMRI
MAB_4189|M.abscessus_ATCC_1997 HVSEPERSAFTAMNDAGFADVVRPFTPGPGVYTYWDYTQLSFPKKRGMRI
:*: ** ** *: ** : *:****:****.:*** ** * ***.:****
Mb0435c|M.bovis_AF2122/97 DFILGSPALAARVMDAQIVREERKG-----KAPSDHAPVLVDLHAG----
Rv0427c|M.tuberculosis_H37Rv DFILGSPALAARVMDAQIVREERKG-----KAPSDHAPVLVDLHAG----
MMAR_0742|M.marinum_M DFILGSPALAGRVVDAQIVRDERKG-----KAPSDHAPVFVDLRPGPAA-
MUL_1374|M.ulcerans_Agy99 DFILGSPALAGRVVDAQIVRDERKG-----KAPSDHAPVFVDLRPGPAA-
MAV_4727|M.avium_104 DFILGSPALARRVTHAQIDREERKG-----KGASDHAPVLVDVSRGEPPS
Mvan_0730|M.vanbaalenii_PYR-1 DFILGSPALAERVVHAEIARDERKTGKNRVGSPSDHAPVVVDLCD-----
Mflv_0177|M.gilvum_PYR-GCK DFILGSPTLAELVTHAEIARDERKTGKNRVGSPSDHAPVVVDLRT-----
TH_0019|M.thermoresistible__bu DFILGSPALAARVTHAEIVRDERRS-KGKVGPPSDHAPVLVQLD------
MSMEG_0829|M.smegmatis_MC2_155 DFILGSPAFAQRVGHAEIVREERKG-----KSPSDHAPVLVELN------
MAB_4189|M.abscessus_ATCC_1997 DFVLGSPEFAKRVGNAHIDREERKG-----KGASDHAPVVVDLD------
**:**** :* * .*.* *:**: .******.*::