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MPNVSRHSSLTPAYTGRLSTNPIPALRLPDESMDPEQTYRFIHDELMLDGSSRLNLATFVTTWMDPEAGQ LMSETFDKNMIDKDEYPVTAAIEQRCVCMVADLFHAEDLRDDDPATAIGVSTIGSSEAVMLAGLAMKWRW RDRVGDGWKGRTPNLVMGSNVQVVWEKFCRYFDVEARYLPMEEGRYVITPEQVLDAVDEDTIGVVAILGT TFTGELEPVAEICAALDKLAATGPDVPVHVDAASGGFVVPFLHPDVVWDFRLPRVVSINVSGHKYGLTYP GIGFVVWRNAEHLPEELVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRLGREGYTTVMRCLSETAQW LSHELASMTGPDNRPVFQVISDGSAIPVVAFKLVEGTRYTVFDISSLLRGYGWQVPAYTMPDNATDVAVL RIVVREGFSANLARALRDDLIEVLGKLEKVGVGGFADEEHFAH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1483 | - | - | 100% (463) | glutamate decarboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3462c | gadB | 0.0 | 79.48% (463) | glutamate decarboxylase GadB |
| M. gilvum PYR-GCK | Mflv_4935 | - | 0.0 | 88.46% (468) | glutamate decarboxylase |
| M. tuberculosis H37Rv | Rv3432c | gadB | 0.0 | 79.48% (463) | glutamate decarboxylase GadB |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3740c | - | 0.0 | 77.97% (463) | glutamate decarboxylase GadB |
| M. marinum M | MMAR_1118 | gadB | 0.0 | 79.91% (463) | glutamate decarboxylase, GadB |
| M. avium 104 | MAV_4373 | - | 0.0 | 79.05% (463) | glutamate decarboxylase |
| M. smegmatis MC2 155 | MSMEG_1574 | - | 0.0 | 80.26% (461) | glutamate decarboxylase |
| M. thermoresistible (build 8) | TH_1695 | gadB | 0.0 | 77.83% (451) | PROBABLE GLUTAMATE DECARBOXYLASE GADB |
| M. ulcerans Agy99 | MUL_0878 | gadB | 0.0 | 80.26% (456) | glutamate decarboxylase, GadB |
CLUSTAL 2.0.9 multiple sequence alignment
MAB_3740c|M.abscessus_ATCC_199 MSKSRDQFRLSAHAGKINASAFSPAYTGRLSTAPVPALRLPDEPMDPQAA
TH_1695|M.thermoresistible__bu -----------------------------LATNPVPSLRLPDDPMAPEAV
MSMEG_1574|M.smegmatis_MC2_155 MSHKQSR-----------GPHVAPAYTGRLAMAPVPSLRLPDEAMDPSAA
Mb3462c|M.bovis_AF2122/97 MSRSHPSVP---------AHSIAPAYTGRMFTAPVPALRMPDESMDPEAA
Rv3432c|M.tuberculosis_H37Rv MSRSHPSVP---------AHSIAPAYTGRMFTAPVPALRMPDESMDPEAA
MMAR_1118|M.marinum_M MSRSHPSVP---------AHSIAPAYTGRLFTAPVPALRLPEESMDPEAA
MUL_0878|M.ulcerans_Agy99 MSRSHSSVP---------AHSIAPAYTGRLFTAPVPALRLPEESMDPEAA
MAV_4373|M.avium_104 MP-QHPSLP---------AHAIAPAYTGRLFTAPVPALRMPDESMDPDAA
Mvan_1483|M.vanbaalenii_PYR-1 MPNVSRHSS------------LTPAYTGRLSTNPIPALRLPDESMDPEQT
Mflv_4935|M.gilvum_PYR-GCK MPNVSRHSS------------LAPAYTGRMSMSPVPALRLPDESMEPEQA
: *:*:**:*::.* *. .
MAB_3740c|M.abscessus_ATCC_199 YRFIHDELMLDGSSRLNLATFVTTWMDPEAEKLMAETFDKNMIDKDEYPA
TH_1695|M.thermoresistible__bu YRFISDELMLDGSSRLNLATFVTTWMDPEAEKLMAQTFDKNMIDKDEYPA
MSMEG_1574|M.smegmatis_MC2_155 YRFIHDELMLDGSSRLNLATFVTTWMDPEAEKLMAETFDKNMIDKDEYPA
Mb3462c|M.bovis_AF2122/97 YRFIHDELMLDGSSRLNLATFVTTWMDPEAEKLMAETFDKNMIDKDEYPA
Rv3432c|M.tuberculosis_H37Rv YRFIHDELMLDGSSRLNLATFVTTWMDPEAEKLMAETFDKNMIDKDEYPA
MMAR_1118|M.marinum_M YRFIHDELMLDGSSRLNLATFVTTWMDPEAGKLMAETFDKNMIDKDEYPA
MUL_0878|M.ulcerans_Agy99 YRFIHDELMLDGSSRLNLATFVTTWMDPEAGKLMAETFDKNMIDKDEYPA
MAV_4373|M.avium_104 YRFIHDELMLDGSSRLNLATFVTTWMDPEAGRLMAETFDKNMIDKDEYPA
Mvan_1483|M.vanbaalenii_PYR-1 YRFIHDELMLDGSSRLNLATFVTTWMDPEAGQLMSETFDKNMIDKDEYPV
Mflv_4935|M.gilvum_PYR-GCK YRFIHDELMLDGSSRLNLATFVTTWMDPEAGQLMSETFDKNMIDKDEYPV
**** ************************* :**::*************.
MAB_3740c|M.abscessus_ATCC_199 TAAIESRCVAMVADLFHADNLSTEDPSSAVGVSTIGSSEAVMLAGLALKW
TH_1695|M.thermoresistible__bu TAAIEQRCVCMVADLFHAEDLRDDDPSSATGVSTIGSSEAVMLAGLALKW
MSMEG_1574|M.smegmatis_MC2_155 TAAIEARCVSMVADLFHAEDLRDDDPASAVGVSTIGSSEAVMLAGLAMKW
Mb3462c|M.bovis_AF2122/97 TAAIEARCVSMVADLFHAEGLRDHDPTSATGVSTIGSSEAVMLGGLALKW
Rv3432c|M.tuberculosis_H37Rv TAAIEARCVSMVADLFHAEGLRDHDPTSATGVSTIGSSEAVMLGGLALKW
MMAR_1118|M.marinum_M TAAIETRCVSMVADLFHAEGLRDDDPSSATGVSTIGSSEAVMLGGLAMKW
MUL_0878|M.ulcerans_Agy99 TAAIETRCVSMVADLFHAEGLRDDDPSSATGVSTIGSSEAVMLGGLAMKW
MAV_4373|M.avium_104 TAAIEQRCVCMVADLFHAEGLNDADPYSACGVSTIGSSEAVMLGGLAMKW
Mvan_1483|M.vanbaalenii_PYR-1 TAAIEQRCVCMVADLFHAEDLRDDDPATAIGVSTIGSSEAVMLAGLAMKW
Mflv_4935|M.gilvum_PYR-GCK TAAIEQRCVCMVADLFHAENLRDDDPSTAIGVSTVGSSEAVMLAGLAMKW
***** ***.********:.* ** :* ****:********.***:**
MAB_3740c|M.abscessus_ATCC_199 RWRTKIGGTDGTGWKGRTPNLVMGSNVQVVWEKFCRYFDVEPRYLPMAKG
TH_1695|M.thermoresistible__bu RWRRRM-EKAGKDWRSRTPNLIMGANVQVVWEKFARYFDVEPRYLPMEKG
MSMEG_1574|M.smegmatis_MC2_155 RWRAKA-----GDWKGRTPNLVMGANVQVVWEKFCRYFDVEPRYLPMAEG
Mb3462c|M.bovis_AF2122/97 RWRQRVG-----SWKGRMPNLVMGSNVQVVWEKFCRYFDVEPRYLPMERG
Rv3432c|M.tuberculosis_H37Rv RWRQRVG-----SWKGRMPNLVMGSNVQVVWEKFCRYFDVEPRYLPMERG
MMAR_1118|M.marinum_M RWRQKVGK----DWKGRTPNLVMGSNVQVVWEKFCRYFDVEPRYLPMEKG
MUL_0878|M.ulcerans_Agy99 RWRQKVGK----DWKGRTPNLVMGSNVQVVWEKFCRYFDVEPRYLPMEKG
MAV_4373|M.avium_104 RWRAKTK-----DWKKRTPNLVMGSNVQVVWEKFCRYFDVEPRYLPMEEG
Mvan_1483|M.vanbaalenii_PYR-1 RWRDRVG----DGWKGRTPNLVMGSNVQVVWEKFCRYFDVEARYLPMEEG
Mflv_4935|M.gilvum_PYR-GCK RWRDKFAGKDGDGWKGRTPNLVMGSNVQVVWEKFCRYFDVEARYLPMEKG
*** : .*: * ***:**:*********.******.***** .*
MAB_3740c|M.abscessus_ATCC_199 RYVITPEQVLEVVDEDTIGVVGILGTTFTGELEPIAAICAALDKLAATPG
TH_1695|M.thermoresistible__bu RYVITPQQVLEHVDEDTIGVVAILGTTFTGELEPVGEICAALDKLAAD-G
MSMEG_1574|M.smegmatis_MC2_155 RYVITPEQVLDAVDEDTIGVVAILGTTYTGELEPVAEICEALDKLAAG-G
Mb3462c|M.bovis_AF2122/97 RYVITPEQVLAAVDENTIGVVAILGTTYTGELEPIAEICAALDKLAAG-G
Rv3432c|M.tuberculosis_H37Rv RYVITPEQVLAAVDENTIGVVAILGTTYTGELEPIAEICAALDKLAAG-G
MMAR_1118|M.marinum_M RYVITPEQVVDAVDEDTIGVVAILGTTYTGELEPVAEICAALDRLAAG-G
MUL_0878|M.ulcerans_Agy99 RYVITPEQVVDAVDEDTFGVVAILGTTYTGELEPVAEICAALDRLAAG-G
MAV_4373|M.avium_104 RYVITPEQVVDAVDEDTIGVVAILGTTYTGELEPVADICGALDKLAAR-G
Mvan_1483|M.vanbaalenii_PYR-1 RYVITPEQVLDAVDEDTIGVVAILGTTFTGELEPVAEICAALDKLAAT-G
Mflv_4935|M.gilvum_PYR-GCK RYVITPEQVLDAVDEDTIGVVAILGTTFTGELEPVAEICAALDALAAG-G
******:**: ***:*:***.*****:******:. ** *** *** *
MAB_3740c|M.abscessus_ATCC_199 KPDVPVHVDAASGGFVVPFLHPELHWDFRLPRVVSINVSGHKYGLTYPGI
TH_1695|M.thermoresistible__bu GPDVPVHVDAASGGFVVPFLHPDLEWDFRLPRVVSINVSGHKYGLTYPGI
MSMEG_1574|M.smegmatis_MC2_155 GVDVPVHVDAASGGFVVPFIHPDLVWDFRLPRVVSINVSGHKYGLTYPGV
Mb3462c|M.bovis_AF2122/97 GVDVPVHVDAASGGFVVPFLHPDLVWDFRLPRVVSINVSGHKYGLTYPGV
Rv3432c|M.tuberculosis_H37Rv GVDVPVHVDAASGGFVVPFLHPDLVWDFRLPRVVSINVSGHKYGLTYPGV
MMAR_1118|M.marinum_M GVDVPVHVDAASGGFVVPFLHPDLKWDFRLPRVVSINVSGHKYGLTYPGV
MUL_0878|M.ulcerans_Agy99 GVDVPVHVDAASGGFVVPFLHPDLKWDFRLPRVVSINVSGHKYGLTYPGV
MAV_4373|M.avium_104 GVDVPVHVDAASGGFVVPFLHPELKWDFRLPRVVSINVSGHKYGLTYPGV
Mvan_1483|M.vanbaalenii_PYR-1 -PDVPVHVDAASGGFVVPFLHPDVVWDFRLPRVVSINVSGHKYGLTYPGI
Mflv_4935|M.gilvum_PYR-GCK GCDVPVHVDAASGGFVVPFLNPLLVWDFRLPRVVSINVSGHKYGLTYPGI
*****************::* : ************************:
MAB_3740c|M.abscessus_ATCC_199 GFVVWRGKEHLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
TH_1695|M.thermoresistible__bu GFVVWRSAEHLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
MSMEG_1574|M.smegmatis_MC2_155 GFVVWRNKEHLPEELVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
Mb3462c|M.bovis_AF2122/97 GFVVWRGPEHLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
Rv3432c|M.tuberculosis_H37Rv GFVVWRGPEHLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
MMAR_1118|M.marinum_M GFVVWRSPEYLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
MUL_0878|M.ulcerans_Agy99 GFVVWRSPEYLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
MAV_4373|M.avium_104 GFVVWRSKEYLPDELVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
Mvan_1483|M.vanbaalenii_PYR-1 GFVVWRNAEHLPEELVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
Mflv_4935|M.gilvum_PYR-GCK GFVVWRNAEHLPEDLVFRVNYLGGDMPTFTLNFSRPGNQVVGQYYNFLRL
******. *:**::************************************
MAB_3740c|M.abscessus_ATCC_199 GRAGYAQVMRCLSETARWFGDELG---KSEH---FEVITDGSAIPVVSFR
TH_1695|M.thermoresistible__bu GRAGYGQVMKTLSDTARWLGDQLR---ASEH---FEVISDGTAIPVVSFR
MSMEG_1574|M.smegmatis_MC2_155 GRAGYTQVMQCLSQTARWLGDELR---DSEH---FELISDGSAIPVVAFR
Mb3462c|M.bovis_AF2122/97 GRDGYTKVMQALSHTARWLGDQLR---EVDH---CEVISDGSAIPVVSFR
Rv3432c|M.tuberculosis_H37Rv GRDGYTKVMQALSHTARWLGDQLR---EVDH---CEVISDGSAIPVVSFR
MMAR_1118|M.marinum_M GREGYINVMQALSETARWLSAQLR---EVDH---CELIADGSAIPVVAFR
MUL_0878|M.ulcerans_Agy99 GREGYINVMQALSETARWLSAQLR---EVDH---CELIADGSAIPVVAFR
MAV_4373|M.avium_104 GREGYTKVMQTLSGTARWLGEQLR---VSEH---CELISDGSAIPVVAFR
Mvan_1483|M.vanbaalenii_PYR-1 GREGYTTVMRCLSETAQWLSHELASMTGPDNRPVFQVISDGSAIPVVAFK
Mflv_4935|M.gilvum_PYR-GCK GRDGYTQVMHALADTAQWLARELEGMTGSDHKPVFEVITDGSAIPVVAFR
** ** **: *: **:*:. :* :: ::*:**:*****:*:
MAB_3740c|M.abscessus_ATCC_199 LKGKRPYTEFDISHSLRAFGWQVPAYTMPDDVTDIAVLRVVVREGFSGDL
TH_1695|M.thermoresistible__bu LTGDRGYTEFDVSHALRAYGWQVPAYTMPENATDVAVLRVVVREGLSADL
MSMEG_1574|M.smegmatis_MC2_155 LKGDPGYTEFDISQALRAHGWQVPAYTMPEGAEDVVVLRVVVREGFSADL
Mb3462c|M.bovis_AF2122/97 LAGDRGYTEFDVSHELRTFGWQVPAYTMPDNATDVAVLRIVVREGLSADL
Rv3432c|M.tuberculosis_H37Rv LAGDRGYTEFDVSHELRTFGWQVPAYTMPDNATDVAVLRIVVREGLSADL
MMAR_1118|M.marinum_M LAGDRGYTEFDLSHELRTFGWQVPAYTMPDNATDVSVLRIVVREGLSADM
MUL_0878|M.ulcerans_Agy99 LAGDRGYTEFDLSHELRTFGWQVPAYTMPDNATDVSVLRIVVREGLSADM
MAV_4373|M.avium_104 LAKDRGYTEFDVSHELRTYGWQVPAYTMPDNATDVSVLRIVVREGLSADL
Mvan_1483|M.vanbaalenii_PYR-1 LVEGTRYTVFDISSLLRGYGWQVPAYTMPDNATDVAVLRIVVREGFSANL
Mflv_4935|M.gilvum_PYR-GCK LTEGAKFTVFDISALLRSYGWQVPAYTMPEDATDIAVLRIVVREGFSANL
* :* **:* ** .**********:.. *: ***:*****:*.::
MAB_3740c|M.abscessus_ATCC_199 ARALRDDLNTVLKGLDELKPNGHFDEVQPFAH
TH_1695|M.thermoresistible__bu ARVLCDDMMTVIEQLDELKPGGQFDSLQPFAH
MSMEG_1574|M.smegmatis_MC2_155 ARALKDDIITVLGQLDALKPRGQFDQLQPFAH
Mb3462c|M.bovis_AF2122/97 ARALHDDAVTALAALDKVKPGGHFDA-QHFAH
Rv3432c|M.tuberculosis_H37Rv ARALHDDAVTALAALDKVKPGGHFDA-QHFAH
MMAR_1118|M.marinum_M ARALHDDAVTSLRTLDKVKPGGNYDG-QHFAH
MUL_0878|M.ulcerans_Agy99 ARALHDDAVTSLRTLDKVKPGGNYDG-QHFAH
MAV_4373|M.avium_104 ARALHDDAVSALTSLDKVKPGGHYDA-QHFAH
Mvan_1483|M.vanbaalenii_PYR-1 ARALRDDLIEVLGKLEKVGVGGFADE-EHFAH
Mflv_4935|M.gilvum_PYR-GCK ARALRDDLREVLGKLDKVGIGGFSDE-EHFAH
**.* ** : *: : * * : ***