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MADTKEPRVAAPETSAGRGAARPTSSRLRAVHELFVAGEVDETFLNSHAVRPVVAQSWKRSLAGGVDPDL DGARAAVAAIERLRETHPLAPALPVIRRLLVDDAMDSGVVVAVSAADGTLLWVEGDPNACRRAEAMNFVP GADWSERSAGTNAPGTALALDRELQIRGSEHFSRVVQPWSCTAAPVHDPTTGALLGAIDLTGGAQVASAQ TLALVRATAVAVENHLALLRVSGVAAEPAARRPHLVVLGADRPRWVTTDRYGHLQATYLTGRHADILVLL SRHPEGLSADHLAVLLDEKDLDVVTVRAEMSRLRKVIGADTLESRPYRLSTAITSDIGEVFEALDAGDVE SALARYPGPLLAQSVSPAIARLRTQLSTTLRDAVLAESRQGRTDLLRRWLELPEGRDDRDGWQALRDSAG LTAVARARAHGHLAGLDFELG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1466 | - | - | 100% (441) | putative GAF sensor protein |
| M. vanbaalenii PYR-1 | Mvan_0790 | - | 3e-30 | 32.68% (257) | putative GAF sensor protein |
| M. vanbaalenii PYR-1 | Mvan_4895 | - | 1e-14 | 28.27% (191) | Fis family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_4955 | - | 0.0 | 84.74% (439) | putative GAF sensor protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2793c | - | 1e-137 | 59.82% (433) | putative transcriptional regulator |
| M. marinum M | MMAR_4913 | - | 1e-151 | 63.59% (434) | putative regulatory protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1542 | - | 1e-163 | 69.05% (420) | transcriptional regulator |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_0493 | - | 1e-150 | 63.59% (434) | putative regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1466|M.vanbaalenii_PYR-1 --MADTK-EPRVAAPETSAGRGAARPTSSRLRAVHELFVAGEVDETFLNS
Mflv_4955|M.gilvum_PYR-GCK --MAASKPSARRASPPP-----PTPPSASRLQAVHELFVAGEVDTGYLNS
MSMEG_1542|M.smegmatis_MC2_155 ---------------------MLTRLPAAKVRAIHDLFIEGQIDPDSLRS
MMAR_4913|M.marinum_M --MATMRTANEIA---------AARLSMPALRALRDRFVAGRVDSTYLDS
MUL_0493|M.ulcerans_Agy99 MLVATMRTANEIA---------AARLSMPALRALRDRFVAGRVDSTYLYS
MAB_2793c|M.abscessus_ATCC_199 --MATTRTSARCG---------PARVSLTSVRDAHELFVTGQVDGSYLES
: . . :: :: *: *.:* * *
Mvan_1466|M.vanbaalenii_PYR-1 HAVRPVVAQSWKRSLAGGVDPDLDGAR--AAVAAIERLRETHPLAPALPV
Mflv_4955|M.gilvum_PYR-GCK HAVRPVVAQSWERSRAGGVDPDIGAARSAAAAAAVDRLRETHPLAPALPV
MSMEG_1542|M.smegmatis_MC2_155 MSLPRVVVDSWRRSLEVGVDPDS-GGRTAAAEAALAELRATHPLAPTLPL
MMAR_4913|M.marinum_M TPVRRIVADSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPL
MUL_0493|M.ulcerans_Agy99 TPVRRIVADSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPL
MAB_2793c|M.abscessus_ATCC_199 IPLPRLVTDSWQRSLATGVDPDRGPGE-AAAATQLTELRNSHPLARALPV
.: :*.:**.** ***** .. : .** :**** .**:
Mvan_1466|M.vanbaalenii_PYR-1 IRRLLVDDAMDSGVVVAVSAADGTLLWVEGDPNACRRAEAMNFVPGADWS
Mflv_4955|M.gilvum_PYR-GCK IRRLLVEDAIGSGVVVAVSAADGTLLWVEGDPGACRRAEAMNFVPGADWS
MSMEG_1542|M.smegmatis_MC2_155 IRRLLVEDAVDSGVVVAITAADGTLLWVEGDRQACRKAEAMNFVPGSDWS
MMAR_4913|M.marinum_M IRRLLIDDAADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWS
MUL_0493|M.ulcerans_Agy99 IRRLLIDDAADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWS
MAB_2793c|M.abscessus_ATCC_199 IRRLLVDHAADSGALVGVTAADGALLWVEGDSGAGRKAAAMNFVPGADWS
*****::.* .**.:*.:::***:****:** * *:* :*:****:***
Mvan_1466|M.vanbaalenii_PYR-1 ERSAGTNAPGTALALDRELQIRGSEHFSRVVQPWSCTAAPVHDPTTGALL
Mflv_4955|M.gilvum_PYR-GCK ERSAGTNAPGTALTLGREMQIHGSEHFSRVVQPWSCTAAPVHDPTTGALL
MSMEG_1542|M.smegmatis_MC2_155 ERSAGTNAPGTALTLDREVQIRGTEHFSRIVHPWSCTAVPVHDPGTGVLL
MMAR_4913|M.marinum_M ERGAGTNAPGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLI
MUL_0493|M.ulcerans_Agy99 ERGAGTNAPGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLI
MAB_2793c|M.abscessus_ATCC_199 ERAVGTNAPGTALALDREVQIRGSEHFCRLVRPWSCTAVPIHDPLSGTPL
**..*********:*.**:**:*:***.*:*:**.***.*:*** :*. :
Mvan_1466|M.vanbaalenii_PYR-1 GAIDLTGGAQVASAQTLALVRATAVAVENHLALLRVSGVAAEPAARRPHL
Mflv_4955|M.gilvum_PYR-GCK GAIDLTGGGQVATSQTLALVRATAVAVENHLALLRLAGAGAEPAARKPHL
MSMEG_1542|M.smegmatis_MC2_155 GAIDLTGGSRVASPQTLALVRATAVAVENHLALLRLTNPVTPVAPERPRL
MMAR_4913|M.marinum_M GAIDLTGGESVASPQTLALLRATGVAVESQLALLR-SGAVQPQPSRQAQL
MUL_0493|M.ulcerans_Agy99 GAIDLTGGESVASPQTLALLRATGVAVESQLALLR-SGAVQPQPSRQAQL
MAB_2793c|M.abscessus_ATCC_199 GSLDLTGGVDIASPQTLALVRATAVAVEHFIALDY-PGRVQVDADTGPRL
*::***** :*:.*****:***.**** :** .. . .:*
Mvan_1466|M.vanbaalenii_PYR-1 VVLGADRPRWVTTDRYGHLQATYLTGRHADILVLLSRHPEGLSADHLAVL
Mflv_4955|M.gilvum_PYR-GCK VVLGGDRPRWVTTDSVGHLQITHLTGRHADILVLLSRHPEGLSADHLAVL
MSMEG_1542|M.smegmatis_MC2_155 SVLGGDRPRWQTTGEDGRARSAVLTGRHADILVLLSRHPEGLSADHLAIL
MMAR_4913|M.marinum_M SVLGAQRPSWRVAG----MGPTMLAGRHADILVLLDRHPEGLSADHLAVL
MUL_0493|M.ulcerans_Agy99 SVLGAQRPSWRVAG----MGPTMLAGRHADILVLLDRHPEGLSADHLAVL
MAB_2793c|M.abscessus_ATCC_199 TLLGVGRPVLHTADG---ERTHRLSGRHAEILALLLRHPEGLSADHLAML
:** ** .:. *:****:**.** ************:*
Mvan_1466|M.vanbaalenii_PYR-1 LDEKDLDVVTVRAEMSRLRKVIGADTLESRPYRLSTAITSDIGEVFEALD
Mflv_4955|M.gilvum_PYR-GCK LDDKDLDVVTVRAEMSRLRKVIGAENLGSRPYRLLTSITSDLGEVYEALD
MSMEG_1542|M.smegmatis_MC2_155 LDDKDLDVVTIRAEMSRLRRVIGSNYIASRPYRLLSPICSDVADVFDALQ
MMAR_4913|M.marinum_M LDDRELDVVTIRAEMSRLRRVVGEQLIASRPYRLTEPIATDVGDVFDAVR
MUL_0493|M.ulcerans_Agy99 LDDRELDVVTARAEMSRLRRVVGEHLIASRPYRLTEPIATDVGDVFDAVR
MAB_2793c|M.abscessus_ATCC_199 LDENDLDVVTIRAEMSRLRRIVGGELIGSRPYRLLKKVRSDMADVFSALR
**:.:***** ********:::* . : ****** : :*:.:*:.*:
Mvan_1466|M.vanbaalenii_PYR-1 AGDVESALARYPGPLLAQSVSPAIARLRTQLSTTLRDAVLAESRQGRTDL
Mflv_4955|M.gilvum_PYR-GCK AADVETALDRYPGPLLTQSVSPAIARLRTQLSATLRAAVLAESAQGRTDL
MSMEG_1542|M.smegmatis_MC2_155 SGDVAAALSAYTGALLPQSVSPAIGRLRTELTASLREAVLARAAVGRLDL
MMAR_4913|M.marinum_M RGDLAEALRHYAGALLPQSVSPGVARVRTELSNTLRAAVVASN---DADL
MUL_0493|M.ulcerans_Agy99 RGDLAEALRHYAGALLPQSVSPGIARVRTELSNTLRAAVVASN---DADL
MAB_2793c|M.abscessus_ATCC_199 AGEIANAMDHYHGELLPRSAAPAVARLRLELSTSLRGAVLASG---DLHL
.:: *: * * **.:*.:*.:.*:* :*: :** **:* .*
Mvan_1466|M.vanbaalenii_PYR-1 LRRWLELPEGRDDRDGWQALRDSAGLTAVARARAHGHLAGLDFELG
Mflv_4955|M.gilvum_PYR-GCK LRRWLEQPEGRDDRDGWQALRDSAGLTPVARARARGHLAGLDFELG
MSMEG_1542|M.smegmatis_MC2_155 LRRWLELPDGRDDRDGWRMLHDHAD-DPVTRAQALGHLAGLDSELA
MMAR_4913|M.marinum_M LANWLRLPEARDDRQGWRMLYDRSPAGSPRRAQAQGHLAGLDFDLA
MUL_0493|M.ulcerans_Agy99 LANWLRLPEAHDDRQGWRMLYDRSPAGSPRRAQAQGHLAGLDFDLA
MAB_2793c|M.abscessus_ATCC_199 LRRWLDLPEARDNREGWQGLHDHPGAGAVARSEARGHLIALDSDLA
* .** *:.:*:*:**: * * . . *:.* *** .** :*.