For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_1542 (-)

annotation: transcriptional regulator
coordinates: 1631951 - 1633222
length: 423

VLTRLPAAKVRAIHDLFIEGQIDPDSLRSMSLPRVVVDSWRRSLEVGVDPDSGGRTAAAEAALAELRATH
PLAPTLPLIRRLLVEDAVDSGVVVAITAADGTLLWVEGDRQACRKAEAMNFVPGSDWSERSAGTNAPGTA
LTLDREVQIRGTEHFSRIVHPWSCTAVPVHDPGTGVLLGAIDLTGGSRVASPQTLALVRATAVAVENHLA
LLRLTNPVTPVAPERPRLSVLGGDRPRWQTTGEDGRARSAVLTGRHADILVLLSRHPEGLSADHLAILLD
DKDLDVVTIRAEMSRLRRVIGSNYIASRPYRLLSPICSDVADVFDALQSGDVAAALSAYTGALLPQSVSP
AIGRLRTELTASLREAVLARAAVGRLDLLRRWLELPDGRDDRDGWRMLHDHADDPVTRAQALGHLAGLDS
ELA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_1542--100% (423)transcriptional regulator
M. smegmatis MC2 155MSMEG_5019-4e-2634.11% (214) regulatory protein
M. smegmatis MC2 155MSMEG_1970-6e-2032.20% (205) sigma factor

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_4955-1e-16269.62% (418) putative GAF sensor protein
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_2793c-1e-14162.47% (421) putative transcriptional regulator
M. marinum MMMAR_4913-1e-15265.25% (423) putative regulatory protein
M. avium 104-----
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_0493-1e-15165.01% (423) putative regulatory protein
M. vanbaalenii PYR-1Mvan_1466-1e-16469.05% (420) putative GAF sensor protein

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4955|M.gilvum_PYR-GCK          --MAASKPSARRASPPP-----PTPPSASRLQAVHELFVAGEVDTGYLNS
Mvan_1466|M.vanbaalenii_PYR-1       --MADTK-EPRVAAPETSAGRGAARPTSSRLRAVHELFVAGEVDETFLNS
MSMEG_1542|M.smegmatis_MC2_155      ---------------------MLTRLPAAKVRAIHDLFIEGQIDPDSLRS
MMAR_4913|M.marinum_M               --MATMRTANEIA---------AARLSMPALRALRDRFVAGRVDSTYLDS
MUL_0493|M.ulcerans_Agy99           MLVATMRTANEIA---------AARLSMPALRALRDRFVAGRVDSTYLYS
MAB_2793c|M.abscessus_ATCC_199      --MATTRTSARCG---------PARVSLTSVRDAHELFVTGQVDGSYLES
                                                           :  . . ::  :: *: *.:*   * *

Mflv_4955|M.gilvum_PYR-GCK          HAVRPVVAQSWERSRAGGVDPDIGAARSAAAAAAVDRLRETHPLAPALPV
Mvan_1466|M.vanbaalenii_PYR-1       HAVRPVVAQSWKRSLAGGVDPDLDGAR--AAVAAIERLRETHPLAPALPV
MSMEG_1542|M.smegmatis_MC2_155      MSLPRVVVDSWRRSLEVGVDPDS-GGRTAAAEAALAELRATHPLAPTLPL
MMAR_4913|M.marinum_M               TPVRRIVADSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPL
MUL_0493|M.ulcerans_Agy99           TPVRRIVADSWRRSLATGVDPDRGGGQIAQLSDTVERLRSAHPLAPVLPL
MAB_2793c|M.abscessus_ATCC_199      IPLPRLVTDSWQRSLATGVDPDRGPGE-AAAATQLTELRNSHPLARALPV
                                     .:  :*.:**.**   *****   ..       : .** :**** .**:

Mflv_4955|M.gilvum_PYR-GCK          IRRLLVEDAIGSGVVVAVSAADGTLLWVEGDPGACRRAEAMNFVPGADWS
Mvan_1466|M.vanbaalenii_PYR-1       IRRLLVDDAMDSGVVVAVSAADGTLLWVEGDPNACRRAEAMNFVPGADWS
MSMEG_1542|M.smegmatis_MC2_155      IRRLLVEDAVDSGVVVAITAADGTLLWVEGDRQACRKAEAMNFVPGSDWS
MMAR_4913|M.marinum_M               IRRLLIDDAADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWS
MUL_0493|M.ulcerans_Agy99           IRRLLIDDAADSGVIVAVTSADGTLLWVDGDRRACRKAESMDFVPGADWS
MAB_2793c|M.abscessus_ATCC_199      IRRLLVDHAADSGALVGVTAADGALLWVEGDSGAGRKAAAMNFVPGADWS
                                    *****::.* .**.:*.:::***:****:**  * *:* :*:****:***

Mflv_4955|M.gilvum_PYR-GCK          ERSAGTNAPGTALTLGREMQIHGSEHFSRVVQPWSCTAAPVHDPTTGALL
Mvan_1466|M.vanbaalenii_PYR-1       ERSAGTNAPGTALALDRELQIRGSEHFSRVVQPWSCTAAPVHDPTTGALL
MSMEG_1542|M.smegmatis_MC2_155      ERSAGTNAPGTALTLDREVQIRGTEHFSRIVHPWSCTAVPVHDPGTGVLL
MMAR_4913|M.marinum_M               ERGAGTNAPGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLI
MUL_0493|M.ulcerans_Agy99           ERGAGTNAPGTALALDRELQIRGSEHFSRLVQPWNCTAVPVHDPSTGVLI
MAB_2793c|M.abscessus_ATCC_199      ERAVGTNAPGTALALDREVQIRGSEHFCRLVRPWSCTAVPIHDPLSGTPL
                                    **..*********:*.**:**:*:***.*:*:**.***.*:*** :*. :

Mflv_4955|M.gilvum_PYR-GCK          GAIDLTGGGQVATSQTLALVRATAVAVENHLALLRLAGAGAEPAARKPHL
Mvan_1466|M.vanbaalenii_PYR-1       GAIDLTGGAQVASAQTLALVRATAVAVENHLALLRVSGVAAEPAARRPHL
MSMEG_1542|M.smegmatis_MC2_155      GAIDLTGGSRVASPQTLALVRATAVAVENHLALLRLTNPVTPVAPERPRL
MMAR_4913|M.marinum_M               GAIDLTGGESVASPQTLALLRATGVAVESQLALLR-SGAVQPQPSRQAQL
MUL_0493|M.ulcerans_Agy99           GAIDLTGGESVASPQTLALLRATGVAVESQLALLR-SGAVQPQPSRQAQL
MAB_2793c|M.abscessus_ATCC_199      GSLDLTGGVDIASPQTLALVRATAVAVEHFIALDY-PGRVQVDADTGPRL
                                    *::*****  :*:.*****:***.****  :**   ..     .   .:*

Mflv_4955|M.gilvum_PYR-GCK          VVLGGDRPRWVTTDSVGHLQITHLTGRHADILVLLSRHPEGLSADHLAVL
Mvan_1466|M.vanbaalenii_PYR-1       VVLGADRPRWVTTDRYGHLQATYLTGRHADILVLLSRHPEGLSADHLAVL
MSMEG_1542|M.smegmatis_MC2_155      SVLGGDRPRWQTTGEDGRARSAVLTGRHADILVLLSRHPEGLSADHLAIL
MMAR_4913|M.marinum_M               SVLGAQRPSWRVAG----MGPTMLAGRHADILVLLDRHPEGLSADHLAVL
MUL_0493|M.ulcerans_Agy99           SVLGAQRPSWRVAG----MGPTMLAGRHADILVLLDRHPEGLSADHLAVL
MAB_2793c|M.abscessus_ATCC_199      TLLGVGRPVLHTADG---ERTHRLSGRHAEILALLLRHPEGLSADHLAML
                                     :**  **   .:.         *:****:**.** ************:*

Mflv_4955|M.gilvum_PYR-GCK          LDDKDLDVVTVRAEMSRLRKVIGAENLGSRPYRLLTSITSDLGEVYEALD
Mvan_1466|M.vanbaalenii_PYR-1       LDEKDLDVVTVRAEMSRLRKVIGADTLESRPYRLSTAITSDIGEVFEALD
MSMEG_1542|M.smegmatis_MC2_155      LDDKDLDVVTIRAEMSRLRRVIGSNYIASRPYRLLSPICSDVADVFDALQ
MMAR_4913|M.marinum_M               LDDRELDVVTIRAEMSRLRRVVGEQLIASRPYRLTEPIATDVGDVFDAVR
MUL_0493|M.ulcerans_Agy99           LDDRELDVVTARAEMSRLRRVVGEHLIASRPYRLTEPIATDVGDVFDAVR
MAB_2793c|M.abscessus_ATCC_199      LDENDLDVVTIRAEMSRLRRIVGGELIGSRPYRLLKKVRSDMADVFSALR
                                    **:.:***** ********:::* . : ******   : :*:.:*:.*: 

Mflv_4955|M.gilvum_PYR-GCK          AADVETALDRYPGPLLTQSVSPAIARLRTQLSATLRAAVLAESAQGRTDL
Mvan_1466|M.vanbaalenii_PYR-1       AGDVESALARYPGPLLAQSVSPAIARLRTQLSTTLRDAVLAESRQGRTDL
MSMEG_1542|M.smegmatis_MC2_155      SGDVAAALSAYTGALLPQSVSPAIGRLRTELTASLREAVLARAAVGRLDL
MMAR_4913|M.marinum_M               RGDLAEALRHYAGALLPQSVSPGVARVRTELSNTLRAAVVASN---DADL
MUL_0493|M.ulcerans_Agy99           RGDLAEALRHYAGALLPQSVSPGIARVRTELSNTLRAAVVASN---DADL
MAB_2793c|M.abscessus_ATCC_199      AGEIANAMDHYHGELLPRSAAPAVARLRLELSTSLRGAVLASG---DLHL
                                     .::  *:  * * **.:*.:*.:.*:* :*: :** **:*       .*

Mflv_4955|M.gilvum_PYR-GCK          LRRWLEQPEGRDDRDGWQALRDSAGLTPVARARARGHLAGLDFELG
Mvan_1466|M.vanbaalenii_PYR-1       LRRWLELPEGRDDRDGWQALRDSAGLTAVARARAHGHLAGLDFELG
MSMEG_1542|M.smegmatis_MC2_155      LRRWLELPDGRDDRDGWRMLHDHAD-DPVTRAQALGHLAGLDSELA
MMAR_4913|M.marinum_M               LANWLRLPEARDDRQGWRMLYDRSPAGSPRRAQAQGHLAGLDFDLA
MUL_0493|M.ulcerans_Agy99           LANWLRLPEAHDDRQGWRMLYDRSPAGSPRRAQAQGHLAGLDFDLA
MAB_2793c|M.abscessus_ATCC_199      LRRWLDLPEARDNREGWQGLHDHPGAGAVARSEARGHLIALDSDLA
                                    * .**  *:.:*:*:**: * * .   .  *:.* *** .** :*.