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VTVIHKTAQDWRVTPNLVDYEKTCATFDWAAAPNLCAEMGPGLCNIAYAAVDRHAHGPTASRTALRFVSE SDGDTGLSVRGLSYGELGLLARKFTDVLRSLDVHKGDRVFTLLGRCPELYVAILGALRNGSVVSPLFSAF GPEPVATRLSIGEADVLITTKAQYRKKIAGIRDQLPSLRHVFVIDDHDDDSGAQTMGFWPRMDAAGDDAP IEPTTADDPALLHFTSGTTGTPKGALHVHGAVTMHYVTGRYALDLHEDDVYWCTADPGWVTGMSYGVIAP LLHGVTSIVDEGDFDAERWYRILESQGVTVWYTAPTAIRMLIKAGAELAAGYRFPRLRFVASVGEPLNAE AVWWGKRVLGLPIHDNWWQTETGGIMIANTPAFDIKPGSMGRPLPGVHATIVHRRDDGAVEVIDTPGVEG ELALKPGWPSMFRGYLHQEERYRKTFADGLYLTGDMAKRDDDGYFWFVGRADDVIKSAGHLIGPFEVENA LTDHPAVAEAAVIGVPDPTVGEVVKAFVTLKDGYQPDDALQRDLMAHARKRLGAAVAPKTIAFADSLPHT RSGKIMRRLLKARELGLPEGDTSTIETTGSASATAVTR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1407 | - | - | 100% (598) | acetyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_5425 | - | 2e-93 | 37.94% (593) | acetyl-CoA synthetase |
| M. vanbaalenii PYR-1 | Mvan_4765 | - | 6e-74 | 33.74% (569) | AMP-dependent synthetase and ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3691 | acs | 2e-94 | 38.81% (590) | acetyl-CoA synthetase |
| M. gilvum PYR-GCK | Mflv_1380 | - | 9e-92 | 37.25% (596) | acetyl-CoA synthetase |
| M. tuberculosis H37Rv | Rv3667 | acs | 2e-94 | 38.81% (590) | acetyl-CoA synthetase |
| M. leprae Br4923 | MLBr_00134 | fadD22 | 2e-32 | 27.77% (515) | acyl-CoA synthetase |
| M. abscessus ATCC 19977 | MAB_0425c | - | 2e-93 | 37.31% (595) | Acetyl-CoA synthetase |
| M. marinum M | MMAR_3488 | acs_1 | 0.0 | 74.66% (584) | acetyl-coenzyme A synthetase Acs_1 |
| M. avium 104 | MAV_0462 | acsA | 1e-102 | 39.73% (589) | acetyl-CoA synthetase |
| M. smegmatis MC2 155 | MSMEG_6179 | - | 3e-95 | 37.78% (585) | acetyl-coenzyme A synthetase |
| M. thermoresistible (build 8) | TH_0966 | acs | 3e-99 | 37.44% (601) | ACETYL-COENZYME A SYNTHETASE ACS (ACETATE--CoA LIGASE) |
| M. ulcerans Agy99 | MUL_4241 | acs | 6e-96 | 38.46% (585) | acetyl-CoA synthetase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1407|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3488|M.marinum_M --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 MCCAIWSASRAPACSASQLSSSHAVRPSVVPDANPRAAPRYSPDLRIQCT
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Mvan_1407|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3488|M.marinum_M --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 SGTPRPCGSSPLAIVTSRETARATTPSAVPNGASVSNSPCATAASTGAGA
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Mvan_1407|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3488|M.marinum_M --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 LDPPVRSSISNSRRGPTSGSVRGRPRCSSSVRSAAASACSRASACIGARC
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Mvan_1407|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3488|M.marinum_M --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 HTVTNEVAPPSSASATRIAPAVTGSGSPSADSCTAPPSSTADARAPRSAD
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Mvan_1407|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3488|M.marinum_M --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6179|M.smegmatis_MC2_155 SAAVCGQPRRLTLCRCARPSASRASSQAAATPGSSNSGARGSGRSVITSH
MAB_0425c|M.abscessus_ATCC_199 --------------------------------------------------
TH_0966|M.thermoresistible__bu --------------------------------------------------
Mb3691|M.bovis_AF2122/97 --------------------------------------------------
Rv3667|M.tuberculosis_H37Rv --------------------------------------------------
MUL_4241|M.ulcerans_Agy99 --------------------------------------------------
MAV_0462|M.avium_104 --------------------------------------------------
MLBr_00134|M.leprae_Br4923 --------------------------------------------------
Mvan_1407|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_3488|M.marinum_M --------------------------------------------------
Mflv_1380|M.gilvum_PYR-GCK ----------------------------------------MTETHVDIPS
MSMEG_6179|M.smegmatis_MC2_155 ASRPLIASSPTVQRNQTTVHQQTCEGPTCVQRSVTRLTAMSNPSHAEVPS
MAB_0425c|M.abscessus_ATCC_199 ----------------------------------------MTETSIE-PD
TH_0966|M.thermoresistible__bu ----------------------------------------MSETHTEAQS
Mb3691|M.bovis_AF2122/97 ----------------------------------------MSESTPEVSS
Rv3667|M.tuberculosis_H37Rv ----------------------------------------MSESTPEVSS
MUL_4241|M.ulcerans_Agy99 -------------------------------MKLNIGDTPVTATSAEEPS
MAV_0462|M.avium_104 ----------------------------------------MTASNTANPP
MLBr_00134|M.leprae_Br4923 --------------------------------MRSENLAALLARQAAEAG
Mvan_1407|M.vanbaalenii_PYR-1 --------------MTVIHKTAQ---DWRVTPNLVDYEKT------CATF
MMAR_3488|M.marinum_M --------------MDVIHKTAH---DSRVAPNLSDYQRA------RAQF
Mflv_1380|M.gilvum_PYR-GCK SYPPDPGFAENANATEALYEQAD---ADRLEFWAEQARRLAWETPFDEVL
MSMEG_6179|M.smegmatis_MC2_155 AYPPPADFAANANATGELYAEAE---KDRLAFWEKQAKRLSWQTPFTDVL
MAB_0425c|M.abscessus_ATCC_199 SYPPSPEFVATANATADLYQAAE---EDRLGFWEQQAGRLHWDEPFGQVL
TH_0966|M.thermoresistible__bu VYPPPAEFAAQSNATADLYREAE---ADRLAFWARQAERLTWAKPFEQVL
Mb3691|M.bovis_AF2122/97 SYPPPAHFAEHANARAELYREAE---EDRLAFWAKQANRLSWTTPFTEVL
Rv3667|M.tuberculosis_H37Rv SYPPPAHFAEHANARAELYREAE---EDRLAFWAKQANRLSWTTPFTEVL
MUL_4241|M.ulcerans_Agy99 SYPPPAEFIEQANARAELYREAE---EDRLAFWAKQADRLSWATPFGEVL
MAV_0462|M.avium_104 SYPPPPQFVEQANAGEQLYREAE---RDRLAFWAEQANRLSWATPFTEVL
MLBr_00134|M.leprae_Br4923 WYDKPAYFAPDVVTHGQIHDGAVRLGEVLRNRGLSAGDRVLLCLPDSPDL
:: * : :
Mvan_1407|M.vanbaalenii_PYR-1 DWAAAPNLCAEMGPGLCNIAYAAVDRHAHGPTASRTALRFVSESDGDTGL
MMAR_3488|M.marinum_M RWTDVPALCEGMGDDKCNIAFAAVDRHCAGPIATRTALRFVTDQSREDQP
Mflv_1380|M.gilvum_PYR-GCK DWSEAP-FAKWFVGGTLNVAYNCVDRHVEAGNGDRVAIHWVGEPVEHSRD
MSMEG_6179|M.smegmatis_MC2_155 DWSDAP-FAKWFVGGKINVAYNCVDRHVEAGNGDRVAIHWEGEPVGDARS
MAB_0425c|M.abscessus_ATCC_199 DWSDAP-FAKWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWEGEP-GDTRT
TH_0966|M.thermoresistible__bu DWSEAP-FAKWFVGGRLNVAYNCVDRHVEAGNGDRVAIYWEGEPVGDSRT
Mb3691|M.bovis_AF2122/97 DWSEAP-FAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRT
Rv3667|M.tuberculosis_H37Rv DWSGAP-FAKWFVGGELNVAYNCVDRHVEAGHGDRVAIHWEGEPVGDRRT
MUL_4241|M.ulcerans_Agy99 DWSDAP-FANWFVGGKLNVAYNCVDRHVEAGNGDRVAIHWVGEPIEDSRT
MAV_0462|M.avium_104 DWSRAP-FAEWFADGTLNVAYNCVDRHVQAGHGDRVAIHWEGESPGDQRS
MLBr_00134|M.leprae_Br4923 VQLLLACLARGIMAFLANPELHRDDYAFPE-RDTAAALVITNGSLRDRFQ
. :. : * * .*: .
Mvan_1407|M.vanbaalenii_PYR-1 SVRGLSYGELGLLARKFTD-------------VLRSLDVHKGDRVFTLLG
MMAR_3488|M.marinum_M PTQDVSYAELGRLVRKFTA-------------VLRGLGVNKGDRVFTIMG
Mflv_1380|M.gilvum_PYR-GCK ----ITYAELKDEVCRAAN-------------ALTNLGLTAGDRVAIYMP
MSMEG_6179|M.smegmatis_MC2_155 ----ITYAELKDEVCKAAN-------------ALTDLGLVAGDRVAIYMP
MAB_0425c|M.abscessus_ATCC_199 ----ITYAELLAQVSQAAN-------------YLTELGLVSGDRVAIYMP
TH_0966|M.thermoresistible__bu ----LTYAQLKDEVSKAAN-------------ALTRLGLRTGDRVAIYMP
Mb3691|M.bovis_AF2122/97 ----LTYSDLLAEVSKAAN-------------ALTDLGLVAGDRVAIYLP
Rv3667|M.tuberculosis_H37Rv ----LTYSDLLAEVSKAAN-------------ALTDLGLVAGDRVAIYLP
MUL_4241|M.ulcerans_Agy99 ----LTYADLQAEVSKAAN-------------ALTGLGLVAGDRVAIYLP
MAV_0462|M.avium_104 ----LTYSELYTQVCKAAN-------------ALTDLGLVAGDRVAIYLP
MLBr_00134|M.leprae_Br4923 SSNVVEPAELLSDATRVEPSDYEPVSGDAYAFATYTSGTTGKPKAAIHRH
: .:* . : . :.
Mvan_1407|M.vanbaalenii_PYR-1 RCPELYVAILGALRN-------GSVVSPLFSAFGP-EPVATRLSIGEADV
MMAR_3488|M.marinum_M RIPELYITMLGALRN-------GSVVSPLFSAFGP-EPIATRVEIGQADV
Mflv_1380|M.gilvum_PYR-GCK MVPEAIIAMLACARL-------GAMHSVVFAGFSA-SALKARIEDAQAKL
MSMEG_6179|M.smegmatis_MC2_155 MIPEAIVAMLACARL-------GVMHSVVFAGFSA-SALRARIEDAEAKL
MAB_0425c|M.abscessus_ATCC_199 MLPEAIVAMLACARL-------GLMHSVVFAGFSA-AALRARIDDAQAKL
TH_0966|M.thermoresistible__bu MIPEAIISMLACARL-------GVLHSVVFAGFSS-SALTARIQDAEAKL
Mb3691|M.bovis_AF2122/97 LIPEAVIAMLACARL-------GIMHSVVFGGFTA-AALQARIVDAQAKL
Rv3667|M.tuberculosis_H37Rv LIPEAVIAMLACARL-------GIMHSVVFGGFTA-AALQARIVDAQAKL
MUL_4241|M.ulcerans_Agy99 LIPEAVIAMLACARL-------GIMHSVVFGGFTA-NTLHARIVDAQAKL
MAV_0462|M.avium_104 LIPEAVIAMLACARL-------GVMHSVVFAGFTA-KALQARIADAAAKL
MLBr_00134|M.leprae_Br4923 ADPFTFVDAMCRKALRLTPQDIGLCSARMYFAYGLGNSVWFPLATGGSAV
* : : * : :: .: .: : . : :
Mvan_1407|M.vanbaalenii_PYR-1 LITTKAQYRK-KIAGIRDQL---------------------PSLRHVFVI
MMAR_3488|M.marinum_M LVTTAAIYRR-KIAKIRERL---------------------TSVRHILVV
Mflv_1380|M.gilvum_PYR-GCK VITTDGQYRRGSAVSLKTGVDEAIDGL-----------GEDSPVEHVLVV
MSMEG_6179|M.smegmatis_MC2_155 VITSDGQYRRGKAASLKEAVDEAVA--------------DQPSVKNVLVV
MAB_0425c|M.abscessus_ATCC_199 VITSDGQWRRGTAAPLKSQVDEALGAAGPATSDL---GGEPSSVEHVLVV
TH_0966|M.thermoresistible__bu LITADGQYRRGNAVPLKTNADEAVQ--------------NQPTVEHVLVV
Mb3691|M.bovis_AF2122/97 LITADGQFRRGKPSPLKAAADEALAAI------------PDCSVEHVLVV
Rv3667|M.tuberculosis_H37Rv LITADGQFRRGKPSPLKAAADEALAAI------------PDCSVEHVLVV
MUL_4241|M.ulcerans_Agy99 LITSDGQFRRGHPAPLKDAADEAVSQ-------------PDSPVEHVLVV
MAV_0462|M.avium_104 LITSDGQFRRGKPAPLKDAADEAVAD-------------PDSPVEHVVVV
MLBr_00134|M.leprae_Br4923 ISSVPVSAESAAMLSTRFEPSVLYGVPSFFARVVGACSPDSFRSLRCVVT
: : . : . .*
Mvan_1407|M.vanbaalenii_PYR-1 DDHDD-DSGAQTMGFW--PRMDAAGDDAPIEPTTADDPALLHFTSGTTGT
MMAR_3488|M.marinum_M DAQSSGDQLPGTLSLW--ELMAAADDNAPAEPTTADDPALLHFTSGTTGT
Mflv_1380|M.gilvum_PYR-GCK RRTGIDTPWTPDRDLWWDETVPEADTEHTPEAFDSEQPLFLLYTSGTTGK
MSMEG_6179|M.smegmatis_MC2_155 RRTGIDVKWTDGRDLWWDETVEQASTEHIPAAFDSEQPLFLLYTSGTTGK
MAB_0425c|M.abscessus_ATCC_199 RRTEIPVEWTEGRDLWWHETVDKADTTHTAEPFDSEHPLFLLYTSGTTGK
TH_0966|M.thermoresistible__bu RRTGLDVPWTEGRDVWWHDAVDNASTEHTPDAFDSEHPLFLLYTSGTTGK
Mb3691|M.bovis_AF2122/97 RRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGK
Rv3667|M.tuberculosis_H37Rv RRTGIEMAWSEGRDLWWHHVVGSASPAHTPEPFDSEHPLFLLYTSGTTGK
MUL_4241|M.ulcerans_Agy99 RRTGIDVSWNDERDLWWHDVVDSASPQHTPEPFDAEQPLFLLYTSGTTGK
MAV_0462|M.avium_104 RRTGIDVSWTDGRDLWWHDVVDAAAPEHTPEPFPAEQPLFLLYTSGTTGK
MLBr_00134|M.leprae_Br4923 AGEALEPALAERLVEFFGGIPILDGIGSSEVGQTFVSNSVDDWRVGTLGK
: . : ** *.
Mvan_1407|M.vanbaalenii_PYR-1 PKG----ALHVHG-AVTMHYVTGRYALDLHED-DVYWCTADPGWVTGMSY
MMAR_3488|M.marinum_M PKG----AIHVHG-AVTMHYVTGLYALDLHPD-DIYWCTADPGWVTGTSY
Mflv_1380|M.gilvum_PYR-GCK PKG----IVHTSGGYLTQTAYTHHNVFDLKPESDVYWCTADIGWVTGHSY
MSMEG_6179|M.smegmatis_MC2_155 PKG----IVHTSGGYLTQSSYTHWNVFDVKPESDVYWCTADIGWVTGHTY
MAB_0425c|M.abscessus_ATCC_199 PKG----IVHTSGGFLTQTSYTHFNIFDLKPETDVYWCTADIGWVTGHTY
TH_0966|M.thermoresistible__bu PKG----IVHTTGGFLTQTAYSHHYVFDIKPETDVFWCTADIGWVTGHSY
Mb3691|M.bovis_AF2122/97 PKG----IMHTSGGYLTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTY
Rv3667|M.tuberculosis_H37Rv PKG----IMHTSGGYLTQCCYTMRTIFDVKPDSDVFWCTADIGWVTGHTY
MUL_4241|M.ulcerans_Agy99 PKG----IVHTSGGYLTQCCYTVHTIFDVKPETDVFWCTADIGWVTGHTY
MAV_0462|M.avium_104 PKG----IVHTSGGYLTQAAYTHYYVFDIKADTDVFWCTADIGWVTGHTY
MLBr_00134|M.leprae_Br4923 VLPPYEIRVVAPDGATAGSGIEGNLWVRGPSIAQSYWNRPDSLLENGDWL
: . . : . : :* .* .*
Mvan_1407|M.vanbaalenii_PYR-1 GVIAPLLHGVTSIVDEGD---FDAERWYRILESQGVTVWYTAPTAIRMLI
MMAR_3488|M.marinum_M GIISPLLHGVTSIVDQAE---FDAERWYRILQDQNVSVWYTAPTGIRMLI
Mflv_1380|M.gilvum_PYR-GCK IVYGPLANGATQVVYEGTPASPTEHRHFEIIEKYGVTIYYTAPTLVRTFM
MSMEG_6179|M.smegmatis_MC2_155 IVYGPLSNGVTQVVYEGTPTSPTEHRHFEVIEKYGVTIYYTAPTLIRTFM
MAB_0425c|M.abscessus_ATCC_199 IVYGPLSNGATQVVYEGTPTSPNEHRHFEIIEKYGVTIYYIAPTLVRTFM
TH_0966|M.thermoresistible__bu IVFGPLANGASQVVYEGTPNSPDEHRHFQIIEKYGVTIYYTAPTLIRTFM
Mb3691|M.bovis_AF2122/97 GVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPTLIRMFM
Rv3667|M.tuberculosis_H37Rv GVYGPLCNGVTEVLYEGTPDTPDRHRHFQIIEKYGVTIYYTAPTLIRMFM
MUL_4241|M.ulcerans_Agy99 GVYGPLANGITEVLYEGTPNTPDEHRHFQIIEEYGVTIYYTAPTLIRTFM
MAV_0462|M.avium_104 GVYGPLANGVTEVLYEGTPDTPTQHRHFEIIEKYGVTIYYTAPTLIRTFM
MLBr_00134|M.leprae_Br4923 NTRDRVRIDGDGWVTYGCRADDTEIVGGVNINPREVERLIIEADAVAEAA
: . : . :: * . :
Mvan_1407|M.vanbaalenii_PYR-1 KAGAELAAGYRFPRLRFVASVGEPLNAEAVW--WGKRVLG---LPIHDNW
MMAR_3488|M.marinum_M KAGAELAAQYCFPHLRFIASVGEPLDPEAVW--WGKRVLG---LPIHDNW
Mflv_1380|M.gilvum_PYR-GCK RWGRQIPAEHDLSSLRLLGSVGEPINPEAWR--WYRMAFGKDKTPIVDTW
MSMEG_6179|M.smegmatis_MC2_155 KLGHQIPASHDLSSLRLLGSVGEPINPEAWR--WYREHIGGGKTPIVDTW
MAB_0425c|M.abscessus_ATCC_199 KWGREIPFAHDLSSLRLLGSVGEPINPEAWR--WYREVIGGNRTPIVDTW
TH_0966|M.thermoresistible__bu KWGREIPDAHDLSSLRLLGSVGEPINPEAWR--WYRKVIGGDRTPVVDTW
Mb3691|M.bovis_AF2122/97 KWGREIPDSHDLSSLRLLGSVGEPINPEAWR--WYRDVIGGGRTPLVDTW
Rv3667|M.tuberculosis_H37Rv KWGREIPDSHDLSSLRLLGSVGEPINPEAWR--WYRDVIGGGRTPLVDTW
MUL_4241|M.ulcerans_Agy99 KWGRAIPDAHDLSSLRLLGSVGEPINPEAWR--WYRDVVGAGHTPIVDTW
MAV_0462|M.avium_104 KWGREIPDAHDLSSLRLLGSVGEPINPEAWR--WYRSVIGADRLPIVDTW
MLBr_00134|M.leprae_Br4923 VVGVREFTGASTLQAFLVPAVGAFIDESVMRDVHRRLLTQLTAFKVPHRF
* :: :** :: .. : : . :
Mvan_1407|M.vanbaalenii_PYR-1 WQTETGGIMIANTP-AFDIKPGSMGRPLPGVHATIVHRRDDGAVEVIDT-
MMAR_3488|M.marinum_M WQTETGGIMIANTP-AFDIKPGSMGRPLPGVDAHILRHNDDGTTSVIDD-
Mflv_1380|M.gilvum_PYR-GCK WQTETGAIMISPLPGVTHCKPGSAMRALPGISAKVVDDDGNELERSPDHG
MSMEG_6179|M.smegmatis_MC2_155 WQTETGAIMISPLPGVTAAKPGSAMTPLPGISAKIVDDEGNQLVPGADEA
MAB_0425c|M.abscessus_ATCC_199 WQTETGSAMISPLPGVTETKPGSAMRAVPGISAKIVDDEGNQLEPASGD-
TH_0966|M.thermoresistible__bu WQTETGAIMISPLPGVTAAKPGAAMAPLPGISAQIVDDDGDRIPNSPEGG
Mb3691|M.bovis_AF2122/97 WQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGA
Rv3667|M.tuberculosis_H37Rv WQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKIVDDHGDPLPPHTEGA
MUL_4241|M.ulcerans_Agy99 WQTETGSAMISPLPGIAAAKPGSAMTPLPGISAKVVDDHGDPLAPETDEG
MAV_0462|M.avium_104 WQTETGATMISPLPGVAAAKPGSAMRPLPGISARIVDDHGDQLVPGIHHG
MLBr_00134|M.leprae_Br4923 AIIERLPRSTNGKLLRNVLRAQSPTKPIWELSLTESQSATKAQLDGRPAS
* :. : .: : .
Mvan_1407|M.vanbaalenii_PYR-1 PGVEGELALKPGWPSMFRGYLHQEERYRKTFA-----DGLYLTG--DMAK
MMAR_3488|M.marinum_M PDEEGELALEPGWPSMFRGYLHAEDRYRKCFS-----DGLYLTG--DLAK
Mflv_1380|M.gilvum_PYR-GCK EHATGYLVLDQPWPAMLRGIWGDPERFKETYWSRFAEKGWYFAG--DGAR
MSMEG_6179|M.smegmatis_MC2_155 EHVTGYLVLDQPWPAMLRGIWGDPQRFKDTYWSRFAEQGWYFAG--DGAR
MAB_0425c|M.abscessus_ATCC_199 EPVTGYLVLDKPWPSMLRGIWGDPERFKETYWSRYAEQGWYFAG--DGAR
TH_0966|M.thermoresistible__bu EPITGYLVLDQPWPAMLRGIWNDPERYRETYWQRFESKGWYFAG--DGAR
Mb3691|M.bovis_AF2122/97 QHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAG--DGAR
Rv3667|M.tuberculosis_H37Rv QHVTGYLVLDQPWPSMLRGIWGDPARYWHSYWSKFSDKGYYFAG--DGAR
MUL_4241|M.ulcerans_Agy99 THVTGYLVLDQPWPSMLRGIWGDPARFHYAYWSKFEDKGYYFAG--DGAR
MAV_0462|M.avium_104 EHVTGYLVLDQPWPSMLRGIWGDPDRYVETYWSRFAEQGWYFAG--DSAY
MLBr_00134|M.leprae_Br4923 NAHAQAAVGHAAGATLKQRLSALQQERERLVVEAVCAEAVKMLGESDPGL
. . .:: : . .. : * * .
Mvan_1407|M.vanbaalenii_PYR-1 RDDDGYFWFVGRADDVIKSAGHLIGPFEVENALTDHPAVAEAAVIGVPDP
MMAR_3488|M.marinum_M KDADGYFWFVGRKDDVIKSAGHLIGPFEVESALTDHPAVAEAAVIGKPDP
Mflv_1380|M.gilvum_PYR-GCK IGSDGEIWVLGRIDDVMNISGHRISTAEVESALVGHSGVAEAAVVGATDE
MSMEG_6179|M.smegmatis_MC2_155 YDSDGHIWVLGRIDDVMNVSGHRISTAEVESALVGHAGVAEAAVVGASDD
MAB_0425c|M.abscessus_ATCC_199 YDSDGAIWVLGRIDDVMNISGHRISTAEVESALVGHDGVAEAAVVGASDE
TH_0966|M.thermoresistible__bu YDADGDIWVLGRIDDVMNVSGHRISTAEVESALVGHSGVAEAAVVGASDP
Mb3691|M.bovis_AF2122/97 IDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTDE
Rv3667|M.tuberculosis_H37Rv IDPDGAIWVLGRIDDVMNVSGHRISTAEVESALVAHSGVAEAAVVGVTDE
MUL_4241|M.ulcerans_Agy99 LDSDGAIWVLGRIDDVMNVSGHRISTAEVESALVGHPGVAEAAVVGVVDD
MAV_0462|M.avium_104 YDRDGAIWVVGRIDDVMNVSGHRLSTAEVESALVGHHGVAEAAVVGATDA
MLBr_00134|M.leprae_Br4923 INRDLAFSDLG-FDSQMTVTLCNRLAVVTGLRLPETVGWDYGSISGLSRY
. * : :* *. :. : . . * . .:: *
Mvan_1407|M.vanbaalenii_PYR-1 TVGEVVKAFVTLKDGYQ-PDDALQRDLMAHARKRLGAAVAPKTIAFADSL
MMAR_3488|M.marinum_M TVGAIIKAFVVLKDGFT-ADDDLRLELLGHARKHLGAAVAPKEIEFADAL
Mflv_1380|M.gilvum_PYR-GCK HTGQAICAFVILKSSAHGGEENMIDELRAEVAKEISPIAKPREIHVVPEL
MSMEG_6179|M.smegmatis_MC2_155 TTGQAICAFVILKASAHGGPENMIEELRAEVAREISPIAKPREIHIVPEL
MAB_0425c|M.abscessus_ATCC_199 TTGQAIVAFVILKASHTVEGDELVSHLKAQVSKEISPIAKPREIHVVPEL
TH_0966|M.thermoresistible__bu QTGQAICAFVILEADAK-DNDNMVEELRAQVAREISPIAKPREIHVVPEL
Mb3691|M.bovis_AF2122/97 TTTQAICAFVVLRANYA-PHDRTAEELRTEVARVISPIARPRDVHVVPEL
Rv3667|M.tuberculosis_H37Rv TTTQAICAFVVLRANYA-PHDRTAEELRTEVARVISPIARPRDVHVVPEL
MUL_4241|M.ulcerans_Agy99 TTTQAICAFVVLRGNYE-QHDGTSEELRAEVAEAISPIARPREVHVVPEL
MAV_0462|M.avium_104 TTGQAICAFVVLCADYQ-VHDGIVDELRAEVAREISPIAKPREVHVVPEL
MLBr_00134|M.leprae_Br4923 LEAELSGVRSRPETPLSANSGAKGLSPIDEELKKVEEMVVAIGASEKQRV
. . . : . . :
Mvan_1407|M.vanbaalenii_PYR-1 PHTRSGKIMRRLLKARELGLPEGDTSTIETTGSASATA-VTR----
MMAR_3488|M.marinum_M PHTSSGKIMRRLLKARELGLPEGDTSTVVGFPEPKPQG-VPL----
Mflv_1380|M.gilvum_PYR-GCK PKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR-ASK----
MSMEG_6179|M.smegmatis_MC2_155 PKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR-ASK----
MAB_0425c|M.abscessus_ATCC_199 PKTRSGKIMRRLLRDVAEGRELGDTSTLVDPSVFEAIR-ASK----
TH_0966|M.thermoresistible__bu PKTRSGKIMRRLLRDVAEGRELGDTSTLVDPNVFEAIR-ATKGGPS
Mb3691|M.bovis_AF2122/97 PKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIR-AAK----
Rv3667|M.tuberculosis_H37Rv PKTRSGKIMRRLLRDVAENRELGDTSTLLDPTVFDAIR-AAK----
MUL_4241|M.ulcerans_Agy99 PKTRSGKIMRRLLRDIAEKRELGDTSTLLDPTVFDAIRNAAK----
MAV_0462|M.avium_104 PKTRSGKIMRRLLRDIAENRELGDTSTLLDPGVFDAIR-AAK----
MLBr_00134|M.leprae_Br4923 ADRLRALLGIIVDGEAGLSKRIQAASTPDEIFQLIDSELCE-----
.. . : : :**