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ATAGTSSPVIAGIDGSATALAAALWAVDEAAGRGAPVHLVYTTKPTDRHAAEYAEDVRRGHECLHEARSA VEATGKPVTVETTVVDGPAAQALISLSEQAQMVCVGSVGIGRYARSILGSTAAEVAERAHCPVAVIRPHP HAGEHGFHWIVVAVTEQPQNAEVVEHALREAALRHVPVLALGDGRTEDSADALERHLRSWRERYPDVHIY PIAGSADVTHFLKKHDEPVMLTVIGSDEAGEVAKIIGHGHSLLRRGTSSALVVRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1387 | - | - | 100% (266) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1382 | - | 9e-39 | 36.13% (274) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2549 | - | 6e-35 | 32.96% (267) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2657c | - | 2e-66 | 49.06% (265) | hypothetical protein Mb2657c |
| M. gilvum PYR-GCK | Mflv_4991 | - | 1e-101 | 68.05% (266) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2624c | - | 2e-66 | 49.06% (265) | hypothetical protein Rv2624c |
| M. leprae Br4923 | MLBr_01390 | - | 6e-09 | 29.05% (148) | hypothetical protein MLBr_01390 |
| M. abscessus ATCC 19977 | MAB_3904 | - | 9e-34 | 35.40% (274) | hypothetical protein MAB_3904 |
| M. marinum M | MMAR_2076 | - | 8e-66 | 49.24% (262) | hypothetical protein MMAR_2076 |
| M. avium 104 | MAV_4010 | - | 1e-26 | 35.65% (230) | hypothetical protein MAV_4010 |
| M. smegmatis MC2 155 | MSMEG_3939 | - | 9e-58 | 48.28% (261) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 2e-21 | 29.47% (302) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2424 | - | 9e-32 | 36.61% (254) | hypothetical protein MUL_2424 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1387|M.vanbaalenii_PYR-1 --MATAGTSSPVIAGIDGSATALAAALWAVDEAAGRGAPVHLVYTTKPTD
Mflv_4991|M.gilvum_PYR-GCK --MATANSDMPVVAGIDGSAAALGAALWAVDEAAARGATLRLVYVTKPSD
MSMEG_3939|M.smegmatis_MC2_155 --MLEPENSAPIVVGIDGSEAGVRAARWAAAEAESRNVPLRLVYATKASH
Mb2657c|M.bovis_AF2122/97 MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKPTH
Rv2624c|M.tuberculosis_H37Rv MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKPTH
MMAR_2076|M.marinum_M --------MKPVIVGIDGSPAGITAVLWATAEAVSAGVPLRLISVLKTAH
MAV_4010|M.avium_104 --MSTAYPAPAIVVGVDGSRAAMHAAVWAIDEAVGRDIPLRLVYVIDPHG
MUL_2424|M.ulcerans_Agy99 --MSN-QAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDPAQ
MAB_3904|M.abscessus_ATCC_1997 -MNEIRTPGPAVLVGIDGSRSAVRAALWAVDEALHRELPLRLVHVTPQTE
TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
MLBr_01390|M.leprae_Br4923 -----MGAYQTVVVGTDGSDSSLRAVDRAGKIAGSDAKLIIASAYLPQHD
::.* *** :. *. . * :
Mvan_1387|M.vanbaalenii_PYR-1 R---------------------HAAE-YAEDVRRGHECLHEARSAVEATG
Mflv_4991|M.gilvum_PYR-GCK R---------------------SAAE-YAGDVRHGRQSLREAQVLVQSTG
MSMEG_3939|M.smegmatis_MC2_155 P---------------------SADD-YYDDVRRGQDALSAAQIDVNRRY
Mb2657c|M.bovis_AF2122/97 P---------------------SPDD-YDRDLAHAERSLREAQSAVEAAG
Rv2624c|M.tuberculosis_H37Rv P---------------------SPDD-YDRDLAHAERSLREAQSAVEAAG
MMAR_2076|M.marinum_M S---------------------SPEE-YEHDLAHAETSLRAAQSAIEATA
MAV_4010|M.avium_104 A---------------------PGGHGPDTRLAAARAALADAHRAVDAFA
MUL_2424|M.ulcerans_Agy99 A---------------------PAGD-RDGRQSSARAALFDVQRAVEATG
MAB_3904|M.abscessus_ATCC_1997 F---------------------PEFS---DERSPAGTAVRHAFRQIGATH
TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPA
MLBr_01390|M.leprae_Br4923 N--------------ARAFDILKDESYKVTGTAPIYEILHDAKERAHAAG
. .
Mvan_1387|M.vanbaalenii_PYR-1 --KPVTVETTVVDGPAAQALISLSEQ--AQMVCVGSVGIGRYARSILGST
Mflv_4991|M.gilvum_PYR-GCK --ESVNVETEIVDGPPAQALVALSEH--AQMVCVGSVGIGRYARSILGST
MSMEG_3939|M.smegmatis_MC2_155 --SEVKVETALVDGPPGRALIDESDR--AAMLCVGSVGIGRYAESILGSI
Mb2657c|M.bovis_AF2122/97 --KLVKIETDIPRGPAGPVLVEASRD--AEMICVGSVGIGRYASSILGST
Rv2624c|M.tuberculosis_H37Rv --KLVKIETDIPRGPAGPVLVEASRD--AEMICVGSVGIGRYASSILGST
MMAR_2076|M.marinum_M --APVKVETDTPRGPAGAVLVEASRD--AELVCVGSVGIGRYARAILGST
MAV_4010|M.avium_104 --QPVKVETEILWGNTAFKLLEQSRS--AVMLCVGQIGLN-HACHGGPAI
MUL_2424|M.ulcerans_Agy99 --QPVKIETEILWGRPLTKLLEESRT--AVMVCVGSIGLN-HARRGEGSV
MAB_3904|M.abscessus_ATCC_1997 --KPVKVEAEIRHGRVADVLLDASRS--AVMLCVGAIGISGADTRKVGST
TH_2494|M.thermoresistible__bu GDDAVRVVTGVVRAAPVPTLVDASKQ--AKLVAVGSRGQGPLRRVLLGSV
MLBr_01390|M.leprae_Br4923 ---AKNVEERPVVGAPVDALVNLAEKTNADLLVVGNVGLSTIAGRLLGSV
: . *: : * :: ** * . :
Mvan_1387|M.vanbaalenii_PYR-1 AAEVAERAHCPVAVIRPHPHAGEHGFHW-IVVAVTEQPQNAEVVEHALRE
Mflv_4991|M.gilvum_PYR-GCK AADVAAAARCPVAVIRPESRVGVDTPNW-IIVAVNDRPHNGAVVEHALQE
MSMEG_3939|M.smegmatis_MC2_155 ALAVAEGAACPVAVIRAQE--DDSAVHW-IAAGN---PADEHVVESAMAE
Mb2657c|M.bovis_AF2122/97 ATELAEKAHCPVAVMRSKVDQPASDINW-IVVRMTDAPDNEAVLEYAARE
Rv2624c|M.tuberculosis_H37Rv ATELAEKAHCPVAVMRSKVDQPASDINW-IVVRMTDAPDNEAVLEYAARE
MMAR_2076|M.marinum_M ATELAEKAHCPVAVIRSNSDQPPPDINW-IVVRVTDAPDNDAVIEYAAHE
MAV_4010|M.avium_104 ATSLVRSALCPVAVVQQAPS--LPAAA--RVSGVVAEVDNGTVLRHAFEE
MUL_2424|M.ulcerans_Agy99 AGTLAGSALCPVAVIQSPAG--AAGAP--KVGEVVAEVDNGSVLRHAFEE
MAB_3904|M.abscessus_ATCC_1997 AAEVLRSVRCPVAVIRDDPSSLRGTSA--VVVEIDESHESVTPLELAAHE
TH_2494|M.thermoresistible__bu SSGLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEE
MLBr_01390|M.leprae_Br4923 PANVSRRAKIDVLIVHTTH-------------------------------
. : . * :::
Mvan_1387|M.vanbaalenii_PYR-1 AALRHVPVLALG----------------DGRTEDSADALERHLRSWRERY
Mflv_4991|M.gilvum_PYR-GCK AALRHAAVLVLG----------------DSRTAASAEVLEQRIRPWHERY
MSMEG_3939|M.smegmatis_MC2_155 ARLRQAPVLVLG----------------DRR---EGDAFIYQVKSIQLRN
Mb2657c|M.bovis_AF2122/97 AKLRQAPILALGGRP-------------EELREIPDGEFERRVQDWHHRH
Rv2624c|M.tuberculosis_H37Rv AKLRQAPILALGGRP-------------EELREIPDGEFERRVQDWHHRH
MMAR_2076|M.marinum_M ARLRQAPILALGGRP-------------EELTDAADGEFERRVQQWGQHH
MAV_4010|M.avium_104 ARLRGVGLCAV-------------------GNPSARVELERRLARWMRLY
MUL_2424|M.ulcerans_Agy99 ARLRNVPLRAISSRVATDHGSE-------DGNRLATAQLTRRLTRWTRLY
MAB_3904|M.abscessus_ATCC_1997 ARLRAAPLRVLLRHRPISLSGQRVATLTRVDRRVAAVHVERRLAPLRVRY
TH_2494|M.thermoresistible__bu ASFRGVDLIALHAWSDADIADIP-TLELSAVQQSAERVLSERLAGFRERY
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mvan_1387|M.vanbaalenii_PYR-1 PDVHIYPIAGSADVTHFLKKHDEPVMLTVIGSDEAGEVAKIIG-HGH---
Mflv_4991|M.gilvum_PYR-GCK PQVHVYPIANRADVAHFLRKHDEPVLLAVLGDDEADEVAQIVG-HGR---
MSMEG_3939|M.smegmatis_MC2_155 PDLHIYPITDRNDVAGFLRRHDEPVQLAVIGESEVAELPRILGPHGRHMF
Mb2657c|M.bovis_AF2122/97 PDVRVYPITTHTGIARFLADHDERVQLAVIGGGEAGQLARLVGPSGH---
Rv2624c|M.tuberculosis_H37Rv PDVRVYPITTHTGIARFLADHDERVQLAVIGGGEAGQLARLVGPSGH---
MMAR_2076|M.marinum_M TDVHVYPITTQAGIARFLADHDERVQLAVIGADEADQVARLVGPSGH---
MAV_4010|M.avium_104 PDVQAESAVLTGGVEQHLRADHRAGRLLVTDA-YRAEA--LCHAG-----
MUL_2424|M.ulcerans_Agy99 PDVRVESAIIAGHACRYMAANAKPDELYVTDS-HAAQVCSVYGAG-----
MAB_3904|M.abscessus_ATCC_1997 PDLDIRALDPVGGTLDYLERHGHTVQLVVVGAGDAAHVQELVGPNGC---
TH_2494|M.thermoresistible__bu PDVSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVSR--
MLBr_01390|M.leprae_Br4923 --------------------------------------------------
Mvan_1387|M.vanbaalenii_PYR-1 SLLRRGTSSALVVRS----
Mflv_4991|M.gilvum_PYR-GCK SALRHGASSALVVRS----
MSMEG_3939|M.smegmatis_MC2_155 HLFEGTTSSVLVARYD---
Mb2657c|M.bovis_AF2122/97 PVFRHAECSVLVVRR----
Rv2624c|M.tuberculosis_H37Rv PVFRHAECSVLVVRR----
MMAR_2076|M.marinum_M PIFRHAECSVLVVRG----
MAV_4010|M.avium_104 -------HSVLAVRCGNL-
MUL_2424|M.ulcerans_Agy99 -------CSVLTVRSGNL-
MAB_3904|M.abscessus_ATCC_1997 GVLGRTHCSVLIAERQRLL
TH_2494|M.thermoresistible__bu AVVNAVTTPVIVAR-----
MLBr_01390|M.leprae_Br4923 -------------------