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MTPPWLGDGPIVVGVDGSQAALNAVRWAAAEALALDASLRLVHAVAAAVPTGSDVVLDHAEKAAKAIRTS LRVEAAATVGAPGAVLLRESARAAMVCIGSRPAQGPPIGCIAKVLAEGAGCPVAIIRTRADGAPQTDGVV SVVLSDDDDTDAVLHLAMHEGRLRHATVRQIDQRTDSWVRRYPDVHVELVAAGTGRQYHRNDARDTGVGL AVVGRRDAAELVALTVPGCHPILGYPDCSVLLVRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1381 | - | - | 100% (245) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_1387 | - | 3e-21 | 31.80% (261) | UspA domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2549 | - | 7e-19 | 30.08% (266) | UspA domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2657c | - | 6e-30 | 32.82% (262) | hypothetical protein Mb2657c |
| M. gilvum PYR-GCK | Mflv_4996 | - | 3e-89 | 69.87% (239) | UspA domain-containing protein |
| M. tuberculosis H37Rv | Rv2624c | - | 6e-30 | 32.82% (262) | hypothetical protein Rv2624c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3904 | - | 3e-20 | 32.85% (274) | hypothetical protein MAB_3904 |
| M. marinum M | MMAR_3481 | - | 2e-58 | 49.60% (248) | hypothetical protein MMAR_3481 |
| M. avium 104 | MAV_4010 | - | 4e-18 | 34.40% (218) | hypothetical protein MAV_4010 |
| M. smegmatis MC2 155 | MSMEG_3939 | - | 1e-27 | 36.59% (246) | universal stress protein family protein |
| M. thermoresistible (build 8) | TH_2494 | - | 1e-12 | 27.37% (274) | PUTATIVE putative conserved hypothetical membrane protein |
| M. ulcerans Agy99 | MUL_2424 | - | 3e-21 | 32.35% (272) | hypothetical protein MUL_2424 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1381|M.vanbaalenii_PYR-1 -MTPPWLGDGPIVVGVDGSQAALNAVRWAAAEALALDASLRLVHAVAA--
Mflv_4996|M.gilvum_PYR-GCK -MSALPLRHKPVVVGVDGSRAAVNAVRWAAAEALAREVCLRLVHAVAS--
MMAR_3481|M.marinum_M ---MKHLDAKSVVAGINGSQAAINAAKWAVDEAISRQLPLRLVYVIPS--
Mb2657c|M.bovis_AF2122/97 MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKP--
Rv2624c|M.tuberculosis_H37Rv MSGRGEPTMKTIIVGIDGSHAAITAALWGVDEAISRAVPLRLVSVIKP--
MSMEG_3939|M.smegmatis_MC2_155 MLE--PENSAPIVVGIDGSEAGVRAARWAAAEAESRNVPLRLVYATKA--
MAV_4010|M.avium_104 --MSTAYPAPAIVVGVDGSRAAMHAAVWAIDEAVGRDIPLRLVYVIDP--
MUL_2424|M.ulcerans_Agy99 --MSN-QAAPAIVVGIDGSRASTHAAVWAVDEAVSRDIPVRLVYIIDP--
MAB_3904|M.abscessus_ATCC_1997 -MNEIRTPGPAVLVGIDGSRSAVRAALWAVDEALHRELPLRLVHVTPQ--
TH_2494|M.thermoresistible__bu --VSSTAAYEGIVVGVDGSAASADAVRWAARSAALRNLQLTLVHVMTATS
::.*::** :. *. *. .* : **
Mvan_1381|M.vanbaalenii_PYR-1 --------AVPT----------GSDVVLDHAEKAAK-------------A
Mflv_4996|M.gilvum_PYR-GCK --------PAP------------DDAVLDRAKIAAL-------------A
MMAR_3481|M.marinum_M --------QQTGSVHAPDWELERAERALAEAEGAVQ-------------S
Mb2657c|M.bovis_AF2122/97 --------THPSP-DDYDRDLAHAERSLREAQSAVE-------------A
Rv2624c|M.tuberculosis_H37Rv --------THPSP-DDYDRDLAHAERSLREAQSAVE-------------A
MSMEG_3939|M.smegmatis_MC2_155 --------SHPSA-DDYYDDVRRGQDALSAAQIDVN-------------R
MAV_4010|M.avium_104 --------HGAPGGHGPDTRLAAARAALADAHRAVD-------------A
MUL_2424|M.ulcerans_Agy99 --------AQAPAGD-RDGRQSSARAALFDVQRAVE-------------A
MAB_3904|M.abscessus_ATCC_1997 --------TEFPEFS---DERSPAGTAVRHAFRQIG-------------A
TH_2494|M.thermoresistible__bu IGAPLVWPAGPIPDSLIQWQEDEARQILADSAEIAENAFQEARAAGPGPA
:
Mvan_1381|M.vanbaalenii_PYR-1 IRTSLRVEAAATVGAPGAVLLRESARAAMVCIGSRP---AQGPPIGCIAK
Mflv_4996|M.gilvum_PYR-GCK SHDSLEVEVVSTVGEPGPVLVRESRDASMICVGSRPVASADAPTIGPTAR
MMAR_3481|M.marinum_M DGHPIEVETVVRAGEPAQVLIDESQETALICVGTARRGPATDGLLGPTAA
Mb2657c|M.bovis_AF2122/97 AGKLVKIETDIPRGPAGPVLVEASRDAEMICVGSVGIGRYASSILGSTAT
Rv2624c|M.tuberculosis_H37Rv AGKLVKIETDIPRGPAGPVLVEASRDAEMICVGSVGIGRYASSILGSTAT
MSMEG_3939|M.smegmatis_MC2_155 RYSEVKVETALVDGPPGRALIDESDRAAMLCVGSVGIGRYAESILGSIAL
MAV_4010|M.avium_104 FAQPVKVETEILWGNTAFKLLEQSRSAVMLCVGQIGLN-HACHGGPAIAT
MUL_2424|M.ulcerans_Agy99 TGQPVKIETEILWGRPLTKLLEESRTAVMVCVGSIGLN-HARRGEGSVAG
MAB_3904|M.abscessus_ATCC_1997 THKPVKVEAEIRHGRVADVLLDASRSAVMLCVGAIGISGADTRKVGSTAA
TH_2494|M.thermoresistible__bu GDDAVRVVTGVVRAAPVPTLVDASKQAKLVAVGSRGQGPLRRVLLGSVSS
:.: . . *: * : ::.:* :
Mvan_1381|M.vanbaalenii_PYR-1 VLAEGAGCPVAIIRTRADGA-PQTDGVVSVVLSDDDDTDAVLHLAMHEGR
Mflv_4996|M.gilvum_PYR-GCK ALAAGADCPVAVIRTGRDGL-PQTAGAIAVVLSDDDDTDATVHLAMHEGR
MMAR_3481|M.marinum_M ALVRGAHCPVAVIRTNPDGS-PTELGVIAVVLNDDADNDEVVHAAMEEGR
Mb2657c|M.bovis_AF2122/97 ELAEKAHCPVAVMRSKVDQP-ASDINWIVVRMTDAPDNEAVLEYAAREAK
Rv2624c|M.tuberculosis_H37Rv ELAEKAHCPVAVMRSKVDQP-ASDINWIVVRMTDAPDNEAVLEYAAREAK
MSMEG_3939|M.smegmatis_MC2_155 AVAEGAACPVAVIRAQEDD---SAVHWIAAGN---PADEHVVESAMAEAR
MAV_4010|M.avium_104 SLVRSALCPVAVVQQ-APS---LPAAARVSGVVAEVDNGTVLRHAFEEAR
MUL_2424|M.ulcerans_Agy99 TLAGSALCPVAVIQS-PAG---AAGAPKVGEVVAEVDNGSVLRHAFEEAR
MAB_3904|M.abscessus_ATCC_1997 EVLRSVRCPVAVIRD-DPSS-LRGTSAVVVEIDESHESVTPLELAAHEAR
TH_2494|M.thermoresistible__bu GLVHHAHCPVAVIREGTPHTPDFAKRPVLVGIDGSESAQRATAVAFEEAS
: . ****::: * *.
Mvan_1381|M.vanbaalenii_PYR-1 LRHATVRQIDQRTD----------------------------SWVRRYPD
Mflv_4996|M.gilvum_PYR-GCK LRHATVRQIDRRTD----------------------------SWVRRYPD
MMAR_3481|M.marinum_M RRHAVVRQIDRRLD----------------------------SWVRRYPD
Mb2657c|M.bovis_AF2122/97 LRQAPILALGGRPEELREIP-------------DGEFERRVQDWHHRHPD
Rv2624c|M.tuberculosis_H37Rv LRQAPILALGGRPEELREIP-------------DGEFERRVQDWHHRHPD
MSMEG_3939|M.smegmatis_MC2_155 LRQAPVLVLGDRRE-------------------GDAFIYQVKSIQLRNPD
MAV_4010|M.avium_104 LRGVGLCAV-------------------GNPSARVELERRLARWMRLYPD
MUL_2424|M.ulcerans_Agy99 LRNVPLRAISSRVATDHGSE-------DGNRLATAQLTRRLTRWTRLYPD
MAB_3904|M.abscessus_ATCC_1997 LRAAPLRVLLRHRPISLSGQRVATLTRVDRRVAAVHVERRLAPLRVRYPD
TH_2494|M.thermoresistible__bu FRGVDLIALHAWSDADIADIP-TLELSAVQQSAERVLSERLAGFRERYPD
* . : : **
Mvan_1381|M.vanbaalenii_PYR-1 VHVELVAAGTGRQYHRNDARDTGVGLAVVGRRDAAELVALTVPGCHPILG
Mflv_4996|M.gilvum_PYR-GCK VHVELVAAGTGRQYARNDLAPNGIGLAVVGRRDAVELAEVGRNNSHPILG
MMAR_3481|M.marinum_M VPVQVVASGTGARSVEN--HSSAIDLAVVGEADADELPGLATPNCHPILG
Mb2657c|M.bovis_AF2122/97 VRVYPITTHTGIARFLAD-HDERVQLAVIGGGEAGQLARLVGPSGHPVFR
Rv2624c|M.tuberculosis_H37Rv VRVYPITTHTGIARFLAD-HDERVQLAVIGGGEAGQLARLVGPSGHPVFR
MSMEG_3939|M.smegmatis_MC2_155 LHIYPITDRNDVAGFLRR-HDEPVQLAVIGESEVAELPRILGPHGRHMFH
MAV_4010|M.avium_104 VQAESAVLTGGVEQHLRA-DHRAGRLLVTDA-YRAEA--LCHAG------
MUL_2424|M.ulcerans_Agy99 VRVESAIIAGHACRYMAA-NAKPDELYVTDS-HAAQVCSVYGAG------
MAB_3904|M.abscessus_ATCC_1997 LDIRALDPVGGTLDYLER-HGHTVQLVVVGAGDAAHVQELVGPNGCGVLG
TH_2494|M.thermoresistible__bu VSVHRRIVGSEPARHLVEASEDAQLVVVGSRGRGGFTGMLLGSVSRAVVN
: : * . :
Mvan_1381|M.vanbaalenii_PYR-1 YPD---CSVLLVRS----
Mflv_4996|M.gilvum_PYR-GCK YPD---CSLLLVRS----
MMAR_3481|M.marinum_M YPD---CSVLLVRH----
Mb2657c|M.bovis_AF2122/97 HAE---CSVLVVRR----
Rv2624c|M.tuberculosis_H37Rv HAE---CSVLVVRR----
MSMEG_3939|M.smegmatis_MC2_155 LFEGTTSSVLVARYD---
MAV_4010|M.avium_104 ------HSVLAVRCGNL-
MUL_2424|M.ulcerans_Agy99 ------CSVLTVRSGNL-
MAB_3904|M.abscessus_ATCC_1997 RTH---CSVLIAERQRLL
TH_2494|M.thermoresistible__bu AVT---TPVIVAR-----
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