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VQPTQQKAWRAGRFWWDWPAQTSESSEAEVRRLTPLSAVIFDLDALADIDSAGHRLAFNAAFAELGLDIE WSAARYRQLQALTDERRRVAAELRKRGVCTECDVLAELLVDEICATKAMILGETILDADITARPGMVELV AEAYGAGIGVGLVSTGNHSWVEPLVRQLVGEGMVRTIVTADEVPLGELYRTALAELGAPAYDSLAFAGSQ ASRRAAVASGVATVYVEGDGAPLRVADCQRMHDSWHETHHRPTAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1359 | - | - | 100% (255) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5013 | - | 1e-112 | 78.91% (256) | hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1495 | - | 5e-68 | 52.17% (276) | HAD-superfamily protein hydrolase subfamily protein IA, variant |
| M. thermoresistible (build 8) | TH_3247 | - | 3e-42 | 38.22% (259) | PUTATIVE putative Haloacid dehalogenase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1359|M.vanbaalenii_PYR-1 ------MQPTQQKAWRAGRFWWDWPAQTSESSEAEVRRLTPLSAVIFDLD
Mflv_5013|M.gilvum_PYR-GCK ---MRSVQSTQQKAWRAGRFWWDW----SETGEPDGRSLTTLSAVIFDLD
MSMEG_1495|M.smegmatis_MC2_155 MGHSDGVSPVQEKAWRAGRFWWDC----TQSADPG---AHPLRALILDLD
TH_3247|M.thermoresistible__bu ------VPRTRERTART--FWWEH-------GRPAGAAEEPLRAVLFNLD
: .:::: *: ***: . . .* *::::**
Mvan_1359|M.vanbaalenii_PYR-1 -ALADIDSAGHRLAFNAAFAELGLDIEWSAARYRQLQALTDERRRVAAEL
Mflv_5013|M.gilvum_PYR-GCK -ALADVERTGHRLAFNAAFAELGLDISWSETRYRQLQELPDERRRVAAEL
MSMEG_1495|M.smegmatis_MC2_155 -AMSDLDLDGHRVVFNAAFAAHGLELTWSPARYRQLLALHDERQRVGAEL
TH_3247|M.thermoresistible__bu GAVADLHRDGHRAAFNAAFAAHGLPVRWDVEQYRHALRIRDDRRRIAAAL
*::*:. *** .****** ** : *. :**: : *:*:*:.* *
Mvan_1359|M.vanbaalenii_PYR-1 RKRGVCTECDVLAELLVDEICATKAMILGETILDADITARPGMVELVAEA
Mflv_5013|M.gilvum_PYR-GCK RKRGVSTECDVLAELLVDEICATKEMILGETILDADITARPGMAELIAEA
MSMEG_1495|M.smegmatis_MC2_155 RKRCVGPECDVLVELLADEICATKDMIFDEMILDLGPSPRAGLVDLVMDA
TH_3247|M.thermoresistible__bu RRRGYGRDS----AALAAEVLRTKDALFERCVLDGDVSPRPGLIDLVTSL
*:* :. *. *: ** :: . :** . :.*.*: :*: .
Mvan_1359|M.vanbaalenii_PYR-1 YGAGIGVGLVSTGNHSWVEPLVRQLVGEGMVRTIVTADEVP----LGELY
Mflv_5013|M.gilvum_PYR-GCK YGAGIAVGLVSCGSHTWVEPLVRQLVGEGMVGAIVTVDDAP----REDLF
MSMEG_1495|M.smegmatis_MC2_155 FADGVPVGVVSGGRRRWVEPLVRQLVGDGLVDTIVTGDDVSDTAARGEAY
TH_3247|M.thermoresistible__bu FVAGIDVAVVSTGARSWVEPLVRQLIGDGLAATVVSRDDLTVVGPDPDVY
: *: *.:** * : *********:*:*:. ::*: *: . : :
Mvan_1359|M.vanbaalenii_PYR-1 RTALAELGAPAYDSLAFAGSQASRRAAVASGVATVYVEG-DGAP------
Mflv_5013|M.gilvum_PYR-GCK RAALAELGAPAHGSLAFAGSQGSRRAAVAAGLPTVLVDGAETAP------
MSMEG_1495|M.smegmatis_MC2_155 RHALWELGVAPHEALGIAGSGAALRAANATGLGTVLVGADTDGAGRPA--
TH_3247|M.thermoresistible__bu GHALWELGLPPEHALAVESSAAGLSAATAAKLTTLVVTTPYTAGQDFTGA
** *** .. :*.. .* .. ** *: : *: * .
Mvan_1359|M.vanbaalenii_PYR-1 ------------LRVADCQRMHDSWHETHHRPTAA
Mflv_5013|M.gilvum_PYR-GCK ------------LRIADCQRIHDSWYETHPRPTAA
MSMEG_1495|M.smegmatis_MC2_155 IAVRADYACADGLRLAVCRRLLGQWWAQHS-PSAA
TH_3247|M.thermoresistible__bu AAVRHRYDEPQPLRASGCVALHRRWLVANG-----
** : * : * :