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RSVQSTQQKAWRAGRFWWDWSETGEPDGRSLTTLSAVIFDLDALADVERTGHRLAFNAAFAELGLDISWS ETRYRQLQELPDERRRVAAELRKRGVSTECDVLAELLVDEICATKEMILGETILDADITARPGMAELIAE AYGAGIAVGLVSCGSHTWVEPLVRQLVGEGMVGAIVTVDDAPREDLFRAALAELGAPAHGSLAFAGSQGS RRAAVAAGLPTVLVDGAETAPLRIADCQRIHDSWYETHPRPTAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_5013 | - | - | 100% (255) | hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1495 | - | 8e-66 | 50.55% (273) | HAD-superfamily protein hydrolase subfamily protein IA, variant |
| M. thermoresistible (build 8) | TH_3247 | - | 1e-44 | 40.00% (255) | PUTATIVE putative Haloacid dehalogenase domain protein |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1359 | - | 1e-112 | 78.91% (256) | hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_5013|M.gilvum_PYR-GCK ---MRSVQSTQQKAWRAGRFWWDW----SETGEPDGRSLTTLSAVIFDLD
Mvan_1359|M.vanbaalenii_PYR-1 ------MQPTQQKAWRAGRFWWDWPAQTSESSEAEVRRLTPLSAVIFDLD
MSMEG_1495|M.smegmatis_MC2_155 MGHSDGVSPVQEKAWRAGRFWWDC----TQSADPG---AHPLRALILDLD
TH_3247|M.thermoresistible__bu ------VPRTRERTART--FWWEH-------GRPAGAAEEPLRAVLFNLD
: .:::: *: ***: . . .* *::::**
Mflv_5013|M.gilvum_PYR-GCK -ALADVERTGHRLAFNAAFAELGLDISWSETRYRQLQELPDERRRVAAEL
Mvan_1359|M.vanbaalenii_PYR-1 -ALADIDSAGHRLAFNAAFAELGLDIEWSAARYRQLQALTDERRRVAAEL
MSMEG_1495|M.smegmatis_MC2_155 -AMSDLDLDGHRVVFNAAFAAHGLELTWSPARYRQLLALHDERQRVGAEL
TH_3247|M.thermoresistible__bu GAVADLHRDGHRAAFNAAFAAHGLPVRWDVEQYRHALRIRDDRRRIAAAL
*::*:. *** .****** ** : *. :**: : *:*:*:.* *
Mflv_5013|M.gilvum_PYR-GCK RKRGVSTECDVLAELLVDEICATKEMILGETILDADITARPGMAELIAEA
Mvan_1359|M.vanbaalenii_PYR-1 RKRGVCTECDVLAELLVDEICATKAMILGETILDADITARPGMVELVAEA
MSMEG_1495|M.smegmatis_MC2_155 RKRCVGPECDVLVELLADEICATKDMIFDEMILDLGPSPRAGLVDLVMDA
TH_3247|M.thermoresistible__bu RRRGYGRDS----AALAAEVLRTKDALFERCVLDGDVSPRPGLIDLVTSL
*:* :. *. *: ** :: . :** . :.*.*: :*: .
Mflv_5013|M.gilvum_PYR-GCK YGAGIAVGLVSCGSHTWVEPLVRQLVGEGMVGAIVTVDDAP----REDLF
Mvan_1359|M.vanbaalenii_PYR-1 YGAGIGVGLVSTGNHSWVEPLVRQLVGEGMVRTIVTADEVP----LGELY
MSMEG_1495|M.smegmatis_MC2_155 FADGVPVGVVSGGRRRWVEPLVRQLVGDGLVDTIVTGDDVSDTAARGEAY
TH_3247|M.thermoresistible__bu FVAGIDVAVVSTGARSWVEPLVRQLIGDGLAATVVSRDDLTVVGPDPDVY
: *: *.:** * : *********:*:*:. ::*: *: . : :
Mflv_5013|M.gilvum_PYR-GCK RAALAELGAPAHGSLAFAGSQGSRRAAVAAGLPTVLVDGAETAP------
Mvan_1359|M.vanbaalenii_PYR-1 RTALAELGAPAYDSLAFAGSQASRRAAVASGVATVYVEG-DGAP------
MSMEG_1495|M.smegmatis_MC2_155 RHALWELGVAPHEALGIAGSGAALRAANATGLGTVLVGADTDGAGRPA--
TH_3247|M.thermoresistible__bu GHALWELGLPPEHALAVESSAAGLSAATAAKLTTLVVTTPYTAGQDFTGA
** *** .. :*.. .* .. ** *: : *: * .
Mflv_5013|M.gilvum_PYR-GCK ------------LRIADCQRIHDSWYETHPRPTAA
Mvan_1359|M.vanbaalenii_PYR-1 ------------LRVADCQRMHDSWHETHHRPTAA
MSMEG_1495|M.smegmatis_MC2_155 IAVRADYACADGLRLAVCRRLLGQWWAQHS-PSAA
TH_3247|M.thermoresistible__bu AAVRHRYDEPQPLRASGCVALHRRWLVANG-----
** : * : * :