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VSARITRLDAVLIGSHVHGDDPLAAAEADGADVVQFFLGNPQSWKKPPPREDAEVLKASPVPIYVHAPYL INVASANNRVRIPSRKILQDTCDAASEIGATAVIVHGGHADDNDMDAGFERWVKALASLKSDVPVYLENT AGGDHAMARHFDTIARLWDHIGDTGIGFCLDTCHAWAAGEALIDAVERIKGITGRIDLVHCNDSRDAAGS GADRHANFGSGQIDPQLLVAVVKAAGAPVICETSDEGRKDDIAFLRDNL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1261 | - | - | 100% (259) | endonuclease IV |
| M. vanbaalenii PYR-1 | Mvan_5320 | - | 8e-05 | 25.79% (159) | periplasmic solute binding protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0689 | end | 1e-119 | 82.66% (248) | endonuclease IV |
| M. gilvum PYR-GCK | Mflv_5093 | - | 1e-140 | 94.78% (249) | endonuclease IV |
| M. tuberculosis H37Rv | Rv0670 | end | 1e-119 | 82.66% (248) | endonuclease IV |
| M. leprae Br4923 | MLBr_01889 | - | 1e-115 | 79.44% (248) | endonuclease IV |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0999 | end | 1e-118 | 80.00% (250) | endonuclease IV (apurinase) |
| M. avium 104 | MAV_4501 | - | 1e-130 | 86.38% (257) | endonuclease IV |
| M. smegmatis MC2 155 | MSMEG_1383 | - | 1e-131 | 89.92% (248) | endonuclease IV |
| M. thermoresistible (build 8) | TH_1167 | end | 1e-125 | 85.14% (249) | PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) |
| M. ulcerans Agy99 | MUL_0751 | end | 1e-118 | 80.00% (250) | endonuclease IV |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1261|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_5093|M.gilvum_PYR-GCK --------------------------------------------------
MAV_4501|M.avium_104 MCGGFFVPPGLSAEREINFTLGAQRETTFTLGAQRETTFTLAGVAGLGGR
TH_1167|M.thermoresistible__bu --------------------------------------------------
MSMEG_1383|M.smegmatis_MC2_155 --------------------------------------------------
Mb0689|M.bovis_AF2122/97 --------------------------------------------------
Rv0670|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0999|M.marinum_M --------------------------------------------------
MUL_0751|M.ulcerans_Agy99 --------------------------------------------------
MLBr_01889|M.leprae_Br4923 --------------------------------------------------
Mvan_1261|M.vanbaalenii_PYR-1 --------------MSARITRLDAVLIGSHVHGDDPLAAAEADGADVVQF
Mflv_5093|M.gilvum_PYR-GCK ------------------------MLIGSHVHGDDPLAAAEADGADVVQF
MAV_4501|M.avium_104 RRARGRRRARGRRRASGHLTRLADVLIGSHVRNDDPLAAAQADGADVVQF
TH_1167|M.thermoresistible__bu ------------------------VLIGSHVDNEDPLAAAQADGADVVQF
MSMEG_1383|M.smegmatis_MC2_155 ------------------------MLIGSHVDNTDPLAAAAADGADVVQF
Mb0689|M.bovis_AF2122/97 ------------------------MLIGSHVSPTDPLAAAEAEGADVVQI
Rv0670|M.tuberculosis_H37Rv ------------------------MLIGSHVSPTDPLAAAEAEGADVVQI
MMAR_0999|M.marinum_M ------------------------MLIGSHVSPQDPLAAAQAEGAEVVQI
MUL_0751|M.ulcerans_Agy99 ------------------------MLIGSHVSPQDPLAAAQAEGAEVVQI
MLBr_01889|M.leprae_Br4923 ------------------------MLIGSHVSSTDPLAAAEVEGADVVQI
:****** ****** .:**:***:
Mvan_1261|M.vanbaalenii_PYR-1 FLGNPQSWKKPPPREDAEVLKASPVPIYVHAPYLINVASANNRVRIPSRK
Mflv_5093|M.gilvum_PYR-GCK FLGNPQSWKKPPPRDDADVLKAASMPIYVHAPYLINVASANNRVRIPSRK
MAV_4501|M.avium_104 FLSNPQSWKKPQPRDDAEALKASSVPLYVHAPYLINVASANNRVRIPSRK
TH_1167|M.thermoresistible__bu FLGDPQSWKKPKHRDDAEALRTSPVPLYVHAPYLINVASANNRVRIPSRK
MSMEG_1383|M.smegmatis_MC2_155 FLGNPQSWKKPKPREDAEVLKASTIPLYVHAPYLINVASANNRVRIPSRK
Mb0689|M.bovis_AF2122/97 FLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRK
Rv0670|M.tuberculosis_H37Rv FLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRK
MMAR_0999|M.marinum_M FLGNPQSWKAPKPREDAAQLKAAALPIYVHAPYLINLASANNKVRIPSRK
MUL_0751|M.ulcerans_Agy99 FLGNPQSWKAPRPREDAAQLKAAALPIYVHAPYLINLASANNKVRIPSRK
MLBr_01889|M.leprae_Br4923 FLGNPQSWKAPTLRSDADVLKATALPVYVHAPYLINVASANSRVRIPSRK
**.:***** * *.** *:::.:*:*********:****.:*******
Mvan_1261|M.vanbaalenii_PYR-1 ILQDTCDAASEIGATAVIVHGGH-ADDNDMDAGFERWVKALASLKSDVPV
Mflv_5093|M.gilvum_PYR-GCK ILQDTCDAASEIGATAVIVHGGH-ADDNDMDAGFERWVKALASLKTDVPV
MAV_4501|M.avium_104 ILQDTCDAAAEINATAVIVHGGH-ADDNDMEAGFERWVKALDYLETDVQV
TH_1167|M.thermoresistible__bu ILQDTCDAAAEINAAAVIVHGGH-ADDKDFEAGFQRWVKALDYLETDVPV
MSMEG_1383|M.smegmatis_MC2_155 ILQDTCDAAAEIGATAVIVHGGH-ADDNDMEAGFTRWVKALDALDTDVPV
Mb0689|M.bovis_AF2122/97 ILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPV
Rv0670|M.tuberculosis_H37Rv ILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPV
MMAR_0999|M.marinum_M ILQQTCDAAADIGAAAVIVHGGHVADDNDLDEGFQRWRKALDQLQTDVPV
MUL_0751|M.ulcerans_Agy99 ILQQTCDAAADIGAAAVIVHGGHVADDNDLDEGFQRWRKALDQLQTDVPV
MLBr_01889|M.leprae_Br4923 ILQQTCDAAADIGAAAVVVHGGYVADDNDLEDGFQRWRKALDQLQTDVPV
***:** **::*.*:**:****: ***:*:: ** ** *** *.::* *
Mvan_1261|M.vanbaalenii_PYR-1 YLENTAGGDHAMARHFDTIARLWDHIGDTGIGFCLDTCHAWAAGEALIDA
Mflv_5093|M.gilvum_PYR-GCK YLENTAGGDHAMARHFDTIARLWDHIGDMGIGFCLDTCHAWAAGEALVDA
MAV_4501|M.avium_104 YLENTAGGDHAMARHFDTIGRLWDRIGDKGIGFCLDTCHAWAAGEALIDA
TH_1167|M.thermoresistible__bu YLENTAGGNHAMARHFDTIARLWDHIGDKGIGFCLDTCHAWAAGEQLIDA
MSMEG_1383|M.smegmatis_MC2_155 YLENTAGGDHAMARHFDTIARLWDHIGDKGIGFCLDTCHAWAAGEALIDA
Mb0689|M.bovis_AF2122/97 YLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDA
Rv0670|M.tuberculosis_H37Rv YLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDA
MMAR_0999|M.marinum_M YLENTAGGEHAMARHFDTIARLWDVIGDTGIGFCLDTCHAWAAGEQLVHG
MUL_0751|M.ulcerans_Agy99 YLENTAGGEHAMARHFDTIARLWDVIGDTGIGFCLDTCHAWAAGEQLVHG
MLBr_01889|M.leprae_Br4923 YLENTAGGDHAMARRFDTIARLWDVIGETGIGFCLDTCHAWAAGEGLIHV
********:*****:****.**** **: **********:***** * .
Mvan_1261|M.vanbaalenii_PYR-1 VERIKGITGRIDLVHCNDSRDAAGSGADRHANFGSGQIDPQLLVAVVKAA
Mflv_5093|M.gilvum_PYR-GCK VERIKGITGRIDLVHCNDSRDAAGSGADRHANFGTGQIDPQLLVAVVTAA
MAV_4501|M.avium_104 VDRIKALTGRIDLVHCNDSRDAAGSGADRHANFGTGQIDPDLLVTVVKAA
TH_1167|M.thermoresistible__bu VERIKAITGRIDLVHCNDSRDAFGSGADRHANFGTGQIDPQLLAAVVKAA
MSMEG_1383|M.smegmatis_MC2_155 VERIKSITGRIDLVHCNDSRDAAGSGADRHANFGAGQIDPQLLAAVVKAA
Mb0689|M.bovis_AF2122/97 VDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAA
Rv0670|M.tuberculosis_H37Rv VDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAA
MMAR_0999|M.marinum_M VDRIKAVTGRIDLVHCNDSRDAAGSGRDRHANLGAGQIDPELLVAAVRAA
MUL_0751|M.ulcerans_Agy99 VDRIKAVTGRIDLVHCNDSRDAAGSGRDRHANLGAGQIDPELLVAAVRAA
MLBr_01889|M.leprae_Br4923 VDRIKAITGRIDLVHCNDSKDEAGSGRDRHANLGSGQIDAELLVAAVKVA
*:***.:************:* *** *****:*:****.:**.:.* .*
Mvan_1261|M.vanbaalenii_PYR-1 GAPVICETSDEGRKDDIAFLRDNL--
Mflv_5093|M.gilvum_PYR-GCK GAPVICETSDEGRKDDIAFLREHVN-
MAV_4501|M.avium_104 AAPVICETADEGRKDDIAFLREHTKS
TH_1167|M.thermoresistible__bu DAPVICETAEAGRKDDIAFLREQVAA
MSMEG_1383|M.smegmatis_MC2_155 DAPVICETAEAGRKDDIAFLREHAG-
Mb0689|M.bovis_AF2122/97 GAPVICETADQGRKDDIAFLRERTGS
Rv0670|M.tuberculosis_H37Rv GAPVICETADQGRKDDIAFLRERTGS
MMAR_0999|M.marinum_M DAPIICETAEEGRKDDIAFLREKLNS
MUL_0751|M.ulcerans_Agy99 DAPIICETAEEGRKDDIAFLREKLNS
MLBr_01889|M.leprae_Br4923 GAPVICETAEEGRKDDIAFLREKTSG
**:****:: **********:.