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M. tuberculosis H37Rv Rv0670 (end)

annotation: endonuclease IV
coordinates: 769792 - 770550
length: 252

VLIGSHVSPTDPLAAAEAEGADVVQIFLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRV
RIPSRKILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPVYLENTAGGDHAMAR
RFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDAVDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLG
SGQIDPDLLVAAVKAAGAPVICETADQGRKDDIAFLRERTGS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0670end-100% (252)endonuclease IV

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0689end1e-146100.00% (252) endonuclease IV
M. gilvum PYR-GCKMflv_5093-1e-11983.06% (248) endonuclease IV
M. leprae Br4923MLBr_01889-1e-12786.00% (250) endonuclease IV
M. abscessus ATCC 19977-----
M. marinum MMMAR_0999end1e-13086.90% (252) endonuclease IV (apurinase)
M. avium 104MAV_4501-1e-11981.75% (252) endonuclease IV
M. smegmatis MC2 155MSMEG_1383-1e-11982.07% (251) endonuclease IV
M. thermoresistible (build 8)TH_1167end1e-11579.37% (252) PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV)
M. ulcerans Agy99MUL_0751end1e-13086.51% (252) endonuclease IV
M. vanbaalenii PYR-1Mvan_1261-1e-11982.66% (248) endonuclease IV

CLUSTAL 2.0.9 multiple sequence alignment


MAV_4501|M.avium_104                MCGGFFVPPGLSAEREINFTLGAQRETTFTLGAQRETTFTLAGVAGLGGR
TH_1167|M.thermoresistible__bu      --------------------------------------------------
MSMEG_1383|M.smegmatis_MC2_155      --------------------------------------------------
Mflv_5093|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1261|M.vanbaalenii_PYR-1       --------------------------------------------------
Rv0670|M.tuberculosis_H37Rv         --------------------------------------------------
Mb0689|M.bovis_AF2122/97            --------------------------------------------------
MMAR_0999|M.marinum_M               --------------------------------------------------
MUL_0751|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01889|M.leprae_Br4923          --------------------------------------------------
                                                                                      

MAV_4501|M.avium_104                RRARGRRRARGRRRASGHLTRLADVLIGSHVRNDDPLAAAQADGADVVQF
TH_1167|M.thermoresistible__bu      ------------------------VLIGSHVDNEDPLAAAQADGADVVQF
MSMEG_1383|M.smegmatis_MC2_155      ------------------------MLIGSHVDNTDPLAAAAADGADVVQF
Mflv_5093|M.gilvum_PYR-GCK          ------------------------MLIGSHVHGDDPLAAAEADGADVVQF
Mvan_1261|M.vanbaalenii_PYR-1       --------------MSARITRLDAVLIGSHVHGDDPLAAAEADGADVVQF
Rv0670|M.tuberculosis_H37Rv         ------------------------MLIGSHVSPTDPLAAAEAEGADVVQI
Mb0689|M.bovis_AF2122/97            ------------------------MLIGSHVSPTDPLAAAEAEGADVVQI
MMAR_0999|M.marinum_M               ------------------------MLIGSHVSPQDPLAAAQAEGAEVVQI
MUL_0751|M.ulcerans_Agy99           ------------------------MLIGSHVSPQDPLAAAQAEGAEVVQI
MLBr_01889|M.leprae_Br4923          ------------------------MLIGSHVSSTDPLAAAEVEGADVVQI
                                                            :******   ****** .:**:***:

MAV_4501|M.avium_104                FLSNPQSWKKPQPRDDAEALKASSVPLYVHAPYLINVASANNRVRIPSRK
TH_1167|M.thermoresistible__bu      FLGDPQSWKKPKHRDDAEALRTSPVPLYVHAPYLINVASANNRVRIPSRK
MSMEG_1383|M.smegmatis_MC2_155      FLGNPQSWKKPKPREDAEVLKASTIPLYVHAPYLINVASANNRVRIPSRK
Mflv_5093|M.gilvum_PYR-GCK          FLGNPQSWKKPPPRDDADVLKAASMPIYVHAPYLINVASANNRVRIPSRK
Mvan_1261|M.vanbaalenii_PYR-1       FLGNPQSWKKPPPREDAEVLKASPVPIYVHAPYLINVASANNRVRIPSRK
Rv0670|M.tuberculosis_H37Rv         FLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRK
Mb0689|M.bovis_AF2122/97            FLGNPQSWKAPKPRDDAAALKAATLPIYVHAPYLINLASANNRVRIPSRK
MMAR_0999|M.marinum_M               FLGNPQSWKAPKPREDAAQLKAAALPIYVHAPYLINLASANNKVRIPSRK
MUL_0751|M.ulcerans_Agy99           FLGNPQSWKAPRPREDAAQLKAAALPIYVHAPYLINLASANNKVRIPSRK
MLBr_01889|M.leprae_Br4923          FLGNPQSWKAPTLRSDADVLKATALPVYVHAPYLINVASANSRVRIPSRK
                                    **.:***** *  *.**  *:::.:*:*********:****.:*******

MAV_4501|M.avium_104                ILQDTCDAAAEINATAVIVHGGH-ADDNDMEAGFERWVKALDYLETDVQV
TH_1167|M.thermoresistible__bu      ILQDTCDAAAEINAAAVIVHGGH-ADDKDFEAGFQRWVKALDYLETDVPV
MSMEG_1383|M.smegmatis_MC2_155      ILQDTCDAAAEIGATAVIVHGGH-ADDNDMEAGFTRWVKALDALDTDVPV
Mflv_5093|M.gilvum_PYR-GCK          ILQDTCDAASEIGATAVIVHGGH-ADDNDMDAGFERWVKALASLKTDVPV
Mvan_1261|M.vanbaalenii_PYR-1       ILQDTCDAASEIGATAVIVHGGH-ADDNDMDAGFERWVKALASLKSDVPV
Rv0670|M.tuberculosis_H37Rv         ILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPV
Mb0689|M.bovis_AF2122/97            ILQETCAAAADIGAAAVIVHGGHVADDNDIDKGFQRWRKALDRLETEVPV
MMAR_0999|M.marinum_M               ILQQTCDAAADIGAAAVIVHGGHVADDNDLDEGFQRWRKALDQLQTDVPV
MUL_0751|M.ulcerans_Agy99           ILQQTCDAAADIGAAAVIVHGGHVADDNDLDEGFQRWRKALDQLQTDVPV
MLBr_01889|M.leprae_Br4923          ILQQTCDAAADIGAAAVVVHGGYVADDNDLEDGFQRWRKALDQLQTDVPV
                                    ***:** **::*.*:**:****: ***:*:: ** ** ***  *.::* *

MAV_4501|M.avium_104                YLENTAGGDHAMARHFDTIGRLWDRIGDKGIGFCLDTCHAWAAGEALIDA
TH_1167|M.thermoresistible__bu      YLENTAGGNHAMARHFDTIARLWDHIGDKGIGFCLDTCHAWAAGEQLIDA
MSMEG_1383|M.smegmatis_MC2_155      YLENTAGGDHAMARHFDTIARLWDHIGDKGIGFCLDTCHAWAAGEALIDA
Mflv_5093|M.gilvum_PYR-GCK          YLENTAGGDHAMARHFDTIARLWDHIGDMGIGFCLDTCHAWAAGEALVDA
Mvan_1261|M.vanbaalenii_PYR-1       YLENTAGGDHAMARHFDTIARLWDHIGDTGIGFCLDTCHAWAAGEALIDA
Rv0670|M.tuberculosis_H37Rv         YLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDA
Mb0689|M.bovis_AF2122/97            YLENTAGGDHAMARRFDTIARLWDVIGDTGIGFCLDTCHTWAAGEALTDA
MMAR_0999|M.marinum_M               YLENTAGGEHAMARHFDTIARLWDVIGDTGIGFCLDTCHAWAAGEQLVHG
MUL_0751|M.ulcerans_Agy99           YLENTAGGEHAMARHFDTIARLWDVIGDTGIGFCLDTCHAWAAGEQLVHG
MLBr_01889|M.leprae_Br4923          YLENTAGGDHAMARRFDTIARLWDVIGETGIGFCLDTCHAWAAGEGLIHV
                                    ********:*****:****.**** **: **********:***** * . 

MAV_4501|M.avium_104                VDRIKALTGRIDLVHCNDSRDAAGSGADRHANFGTGQIDPDLLVTVVKAA
TH_1167|M.thermoresistible__bu      VERIKAITGRIDLVHCNDSRDAFGSGADRHANFGTGQIDPQLLAAVVKAA
MSMEG_1383|M.smegmatis_MC2_155      VERIKSITGRIDLVHCNDSRDAAGSGADRHANFGAGQIDPQLLAAVVKAA
Mflv_5093|M.gilvum_PYR-GCK          VERIKGITGRIDLVHCNDSRDAAGSGADRHANFGTGQIDPQLLVAVVTAA
Mvan_1261|M.vanbaalenii_PYR-1       VERIKGITGRIDLVHCNDSRDAAGSGADRHANFGSGQIDPQLLVAVVKAA
Rv0670|M.tuberculosis_H37Rv         VDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAA
Mb0689|M.bovis_AF2122/97            VDRIKAITGRIDLVHCNDSRDEAGSGRDRHANLGSGQIDPDLLVAAVKAA
MMAR_0999|M.marinum_M               VDRIKAVTGRIDLVHCNDSRDAAGSGRDRHANLGAGQIDPELLVAAVRAA
MUL_0751|M.ulcerans_Agy99           VDRIKAVTGRIDLVHCNDSRDAAGSGRDRHANLGAGQIDPELLVAAVRAA
MLBr_01889|M.leprae_Br4923          VDRIKAITGRIDLVHCNDSKDEAGSGRDRHANLGSGQIDAELLVAAVKVA
                                    *:***.:************:*  *** *****:*:****.:**.:.* .*

MAV_4501|M.avium_104                AAPVICETADEGRKDDIAFLREHTKS
TH_1167|M.thermoresistible__bu      DAPVICETAEAGRKDDIAFLREQVAA
MSMEG_1383|M.smegmatis_MC2_155      DAPVICETAEAGRKDDIAFLREHAG-
Mflv_5093|M.gilvum_PYR-GCK          GAPVICETSDEGRKDDIAFLREHVN-
Mvan_1261|M.vanbaalenii_PYR-1       GAPVICETSDEGRKDDIAFLRDNL--
Rv0670|M.tuberculosis_H37Rv         GAPVICETADQGRKDDIAFLRERTGS
Mb0689|M.bovis_AF2122/97            GAPVICETADQGRKDDIAFLRERTGS
MMAR_0999|M.marinum_M               DAPIICETAEEGRKDDIAFLREKLNS
MUL_0751|M.ulcerans_Agy99           DAPIICETAEEGRKDDIAFLREKLNS
MLBr_01889|M.leprae_Br4923          GAPVICETAEEGRKDDIAFLREKTSG
                                     **:****:: **********:.