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NTSRTTIQRDRAAGALVGLASGDAVGAGYEFDPPMAAGHPVAMIGGGPAPFQPGEWTDGTSMAIAIAEIA ATGADLRHEDSLDYIAERWHWWSRTAKGIDTQTATVLSMAGSQGISAQMCRRAAQDLHERIGRSGGDRSL MRTAPVALSYLDDEDALVVAARLISELTHFHPEAGDACVLWCLAIRHAVLTGDLEVRIGLPHIPSGRRDT WAARVAEAEQAGAYHFALGNERAASALQAAWAAVVHTPTPTDDPVCRVFRADHLRLAIETAARARGHTNT VAAIAGGLVGAAYGASAVPWHWRLTLKGWPGLNTRGLVKLANLTVEGGDARTFAVGYRACRNVPRPVRHP DDDALWLGAAPSLHSLPAGIDAVVSLCPVEDGHIPAGVVHLHADIGCSNRELALLDSARAVEALRAQGRT VFAHGATATNRAPAVAVLYAARCRGRSIDAALDGVRAVMSDVDMEPALRRALHVLHPAGGGGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1105 | - | - | 100% (484) | ADP-ribosylation/crystallin J1 |
| M. vanbaalenii PYR-1 | Mvan_1100 | - | e-123 | 51.58% (475) | ADP-ribosylation/crystallin J1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5181 | - | 2e-85 | 55.03% (318) | ADP-ribosylation/crystallin J1 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2353 | - | 6e-08 | 24.04% (312) | ADP-ribosylglycohydrolase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1272 | - | 1e-158 | 59.15% (492) | putative ribosylglycohydrolase |
| M. thermoresistible (build 8) | TH_0049 | - | 1e-150 | 58.58% (466) | putative ribosylglycohydrolase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_1272|M.smegmatis_MC2_155 MGSSRIELTAAQRDRAVGVLLGAAAGDALGAGYELNRPLAPDHPVGMIGG
TH_0049|M.thermoresistible__bu ------------------VLLATAAGDALGAGYEFDPPMGDDEPVGMIGG
Mvan_1105|M.vanbaalenii_PYR-1 MNTSR---TTIQRDRAAGALVGLASGDAVGAGYEFDPPMAAGHPVAMIGG
Mflv_5181|M.gilvum_PYR-GCK --------MTSHDDRIAGVLLGTAAGDALGAPYEFQPPRGPDLDVRMAGG
MAB_2353|M.abscessus_ATCC_1997 -MHLNPILGCMPDSRVRATLLGGALGDALGGFVEFDSIEQIRLQFGRHGI
.*:. * ***:*. *:: . *
MSMEG_1272|M.smegmatis_MC2_155 GLG-PFAPGEWTDDTSMAIAIAEIASTGEDLRKEKPLDYLVERWEWWSRT
TH_0049|M.thermoresistible__bu GLG-PFAPGEWTDDTAMALAIAEIAATGVDLRDDSVQDHIVERWYEWART
Mvan_1105|M.vanbaalenii_PYR-1 GPA-PFQPGEWTDGTSMAIAIAEIAATGADLRHEDSLDYIAERWHWWSRT
Mflv_5181|M.gilvum_PYR-GCK G---VWEPGEWTDDTAMAIAIAEVAATGADLRDERAQDAILTRWREWSHH
MAB_2353|M.abscessus_ATCC_1997 AEPPAGQPMLITDDTQMTLFTAEAVIRARRIHDHEPAEIAHRAYLRWLHT
. * **.* *:: ** . . ::.. : : * :
MSMEG_1272|M.smegmatis_MC2_155 APDVG--------VQTRTVLSETAA-RGLCAQTARAVSEELHRSSGRTA-
TH_0049|M.thermoresistible__bu AKDVG--------NQTSAVLSAVGR-RGISARAAREESAVWHESAGRSG-
Mvan_1105|M.vanbaalenii_PYR-1 AKGID--------TQTATVLSMAGS-QGISAQMCRRAAQDLHERIGRSG-
Mflv_5181|M.gilvum_PYR-GCK TKNIG--------VQTSSVLHAASRGAAITAARARDASRAHHARSGRSG-
MAB_2353|M.abscessus_ATCC_1997 QGGHPPADVIDGWLVAVPELHSLRAPGHTCLSALEHTSSAARERGSRTQR
. : . * . : : .*:
MSMEG_1272|M.smegmatis_MC2_155 -----GNGSLMRTSPVALAYLDDEAALVQAARTISELTHFDPNAGDACVL
TH_0049|M.thermoresistible__bu -----GNGSLMRTAPVALAHLDDEDALADAARAISELTHFDPEAGDACVM
Mvan_1105|M.vanbaalenii_PYR-1 -----GDRSLMRTAPVALSYLDDEDALVVAARLISELTHFHPEAGDACVL
Mflv_5181|M.gilvum_PYR-GCK -----GNGSLMRTAPVALAYLDDEGAMVEAARAISALTHFDPEAGDACVL
MAB_2353|M.abscessus_ATCC_1997 LNNSKGCGAVMRAAPVGFAGADPASIFVMSA-DIGALTHSHPTGYLSAAA
* ::**::**.:: * :. :* *. *** .* . :..
MSMEG_1272|M.smegmatis_MC2_155 WCTAIRHTVLTGEIDVRVG-LSHIVSERRRLWEARLAEAEASPPSAFCDN
TH_0049|M.thermoresistible__bu WCLAIRHAVLTGGFDVRIG-LDHIDGSRRDLWAARLEEAESSRPEAFAGK
Mvan_1105|M.vanbaalenii_PYR-1 WCLAIRHAVLTGDLEVRIG-LPHIPSGRRDTWAARVAEAEQAGAYHFALG
Mflv_5181|M.gilvum_PYR-GCK WCSAIRHGVLTGDLDVRVG-LRHLGDEGRVTWSERLDLAETSRPRDFP-K
MAB_2353|M.abscessus_ATCC_1997 LSVIIAEVCAGKTIPVAVETASALLRAEPDHEETYRALRRAVELADTRLT
. * . : * : : .
MSMEG_1272|M.smegmatis_MC2_155 NGWVVAALQAAWSAISTTPVPHEDPRSEVFRADHLRLALEAAVRGGGDTD
TH_0049|M.thermoresistible__bu NGWVVAALQGAWSSIVTTPIPVDDPAAGLFRADHLRLALEAAVRGGGDTD
Mvan_1105|M.vanbaalenii_PYR-1 NERAASALQAAWAAVVHTPTPTDDPVCRVFRADHLRLAIETAARARGHTN
Mflv_5181|M.gilvum_PYR-GCK NGWVVSALQAAWSAIATTASSEADP--NAAGTGHLPRGLDAAVRAGFDTD
MAB_2353|M.abscessus_ATCC_1997 PEQIAARLGGGWVGEEALAIG----VYAALAAHDFKDGIRLSVNHSGDSD
.: * ..* . . : .: .: :.. .::
MSMEG_1272|M.smegmatis_MC2_155 TVAAIAGGLLGAAYGASAVPSQWRRLLHGWPGLRTRGLTALADRTVNKGR
TH_0049|M.thermoresistible__bu TVAAIAGGLLGAVHGASAVPAQWRLLLTGWPGLNTRGLVQLATDIVSGGQ
Mvan_1105|M.vanbaalenii_PYR-1 TVAAIAGGLVGAAYGASAVPWHWRLTLKGWPGLNTRGLVKLANLTVEGGD
Mflv_5181|M.gilvum_PYR-GCK TVAAIAGGLLGAVHGASAVPRAWRELLHGWPGLDAAELAELAHAAAR---
MAB_2353|M.abscessus_ATCC_1997 STGAIAGNILGAMCGTESLPQDW------LDELELREVITTIADDLVGPP
:..****.::** *:.::* * * :
MSMEG_1272|M.smegmatis_MC2_155 PVEFNQSYAAGRETPEPVRHPHDDGVWIGIAYSLNRLPSDIDAVVSLCRV
TH_0049|M.thermoresistible__bu AESFDQAYGAYPESALAVRHPHDVDIWIGNAAALHRLPDGVDAVVSLCRV
Mvan_1105|M.vanbaalenii_PYR-1 ARTFAVGYRACRNVPRPVRHPDDDALWLGAAPSLHSLPAGIDAVVSLCPV
Mflv_5181|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2353|M.abscessus_ATCC_1997 GPDWDERYPPR---------------------------------------
MSMEG_1272|M.smegmatis_MC2_155 ADGHIPLRVVHLDVPLLDQEGANPNLDFVVLDTVRAIEQLRAEGRTVFVH
TH_0049|M.thermoresistible__bu ADEHIPDGATHLDVRLIDRVGDNANLDFVLLDTVRAVEQLRAENRTVYLH
Mvan_1105|M.vanbaalenii_PYR-1 EDGHIPAGVVHLHADIG-----CSNRELALLDSARAVEALRAQGRTVFAH
Mflv_5181|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2353|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_1272|M.smegmatis_MC2_155 SAAAQNRAPAVAALYGARRQGLGIDRALREVCAVLPSAQPNPDLRAALRR
TH_0049|M.thermoresistible__bu CVHAYSRTPTIAALYGARRQGIGIERALDEVCAVLSGANPNPEFRDALRR
Mvan_1105|M.vanbaalenii_PYR-1 GATATNRAPAVAVLYAARCRGRSIDAALDGVRAVMSDVDMEPALRRALHV
Mflv_5181|M.gilvum_PYR-GCK --------------------------------------------------
MAB_2353|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_1272|M.smegmatis_MC2_155 LHVVEAGAR
TH_0049|M.thermoresistible__bu LHSGD----
Mvan_1105|M.vanbaalenii_PYR-1 LHPAGGGGR
Mflv_5181|M.gilvum_PYR-GCK ---------
MAB_2353|M.abscessus_ATCC_1997 ---------