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TARDDRIEGVLLGTAAGDALGAPYEFQPPRGTELDVAMTGGGPWTPGEWTDDTAMAVAIAEVAATGADLR DEAAQDAIVARWHEWSRSAKDVGIQTRAVLSAAARGGEITAHRARREAGIHHEHTGRSGGNGSLMRTAPV ALAYLDDEAAMVQGARALSELTHFDPDAGDACVLWCSAIRHAVLTGEIDIRIGLGHIDVERRELWATRLE AAERSRPSDFPKNGWVVQALQAAWSAIATTAVPADDPVAGTFRAGHLRDGLDAAVRAGFDTDTVAAIAGG LLGAAYGASAVPLEWRTLLHGWPGVRARELVKLSGRIARRGAVDRFDPRYPGYQVGVMVPHPYDDGVLLA GIGALHELPAGVDAVVSLCRVGDEVVRRDIPHVEVRLIDRPGAHDNPHLDFVMLEAVRAVERFRGEGKTV LLHCVEAHSRTPSVAALYGARLRGVGTGEALHAVCGALPDASPNPAFREALARFDSAHAAAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_1100 | - | - | 100% (483) | ADP-ribosylation/crystallin J1 |
| M. vanbaalenii PYR-1 | Mvan_1105 | - | e-123 | 51.58% (475) | ADP-ribosylation/crystallin J1 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_5181 | - | 1e-134 | 73.52% (321) | ADP-ribosylation/crystallin J1 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2353 | - | 8e-13 | 25.48% (314) | ADP-ribosylglycohydrolase |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1272 | - | 1e-155 | 59.18% (485) | putative ribosylglycohydrolase |
| M. thermoresistible (build 8) | TH_0049 | - | 1e-167 | 63.91% (471) | putative ribosylglycohydrolase |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_1100|M.vanbaalenii_PYR-1 --------MTARDDRIEGVLLGTAAGDALGAPYEFQPPRGTELDVAMTGG
Mflv_5181|M.gilvum_PYR-GCK --------MTSHDDRIAGVLLGTAAGDALGAPYEFQPPRGPDLDVRMAGG
MSMEG_1272|M.smegmatis_MC2_155 MGSSRIELTAAQRDRAVGVLLGAAAGDALGAGYELNRPLAPDHPVGMIGG
TH_0049|M.thermoresistible__bu ------------------VLLATAAGDALGAGYEFDPPMGDDEPVGMIGG
MAB_2353|M.abscessus_ATCC_1997 -MHLNPILGCMPDSRVRATLLGGALGDALGGFVEFDSIEQIRLQFGRHGI
.**. * *****. *:: . *
Mvan_1100|M.vanbaalenii_PYR-1 ---GPWTPGEWTDDTAMAVAIAEVAATGADLRDEAAQDAIVARWHEWSRS
Mflv_5181|M.gilvum_PYR-GCK ---GVWEPGEWTDDTAMAIAIAEVAATGADLRDERAQDAILTRWREWSHH
MSMEG_1272|M.smegmatis_MC2_155 GL-GPFAPGEWTDDTSMAIAIAEIASTGEDLRKEKPLDYLVERWEWWSRT
TH_0049|M.thermoresistible__bu GL-GPFAPGEWTDDTAMALAIAEIAATGVDLRDDSVQDHIVERWYEWART
MAB_2353|M.abscessus_ATCC_1997 AEPPAGQPMLITDDTQMTLFTAEAVIRARRIHDHEPAEIAHRAYLRWLHT
* **** *:: ** . . ::.. : : * :
Mvan_1100|M.vanbaalenii_PYR-1 AKDVG--------IQTRAVLSAAARGGEITAHRARREAGIHHEHTGRSG-
Mflv_5181|M.gilvum_PYR-GCK TKNIG--------VQTSSVLHAASRGAAITAARARDASRAHHARSGRSG-
MSMEG_1272|M.smegmatis_MC2_155 APDVG--------VQTRTVLSETAARG-LCAQTARAVSEELHRSSGRTA-
TH_0049|M.thermoresistible__bu AKDVG--------NQTSAVLSAVGRRG-ISARAAREESAVWHESAGRSG-
MAB_2353|M.abscessus_ATCC_1997 QGGHPPADVIDGWLVAVPELHSLRAPGHTCLSALEHTSSAARERGSRTQR
. : . * . . : : .*:
Mvan_1100|M.vanbaalenii_PYR-1 -----GNGSLMRTAPVALAYLDDEAAMVQGARALSELTHFDP----DAGD
Mflv_5181|M.gilvum_PYR-GCK -----GNGSLMRTAPVALAYLDDEGAMVEAARAISALTHFDP----EAGD
MSMEG_1272|M.smegmatis_MC2_155 -----GNGSLMRTSPVALAYLDDEAALVQAARTISELTHFDP----NAGD
TH_0049|M.thermoresistible__bu -----GNGSLMRTAPVALAHLDDEDALADAARAISELTHFDP----EAGD
MAB_2353|M.abscessus_ATCC_1997 LNNSKGCGAVMRAAPVGFAGADPASIFVMSA-DIGALTHSHPTGYLSAAA
* *::**::**.:* * :. .* :. *** .* .*.
Mvan_1100|M.vanbaalenii_PYR-1 ACVLWCSAIRHAVLTGEIDIRIGLGHIDVERRELWATRLEAAERSRPSDF
Mflv_5181|M.gilvum_PYR-GCK ACVLWCSAIRHGVLTGDLDVRVGLRHLGDEGRVTWSERLDLAETSRPRDF
MSMEG_1272|M.smegmatis_MC2_155 ACVLWCTAIRHTVLTGEIDVRVGLSHIVSERRRLWEARLAEAEASPPSAF
TH_0049|M.thermoresistible__bu ACVMWCLAIRHAVLTGGFDVRIGLDHIDGSRRDLWAARLEEAESSRPEAF
MAB_2353|M.abscessus_ATCC_1997 LSVIIAEVCAGKTIPVAVETASALLRAEPDHEETYRALRRAVELADTRLT
.*: . . .:. .: .* : . . : .* : .
Mvan_1100|M.vanbaalenii_PYR-1 P-KNGWVVQALQAAWSAIATTAVPADDPVAGTFRAGHLRDGLDAAVRAGF
Mflv_5181|M.gilvum_PYR-GCK P-KNGWVVSALQAAWSAIATTASSEADPNAAG--TGHLPRGLDAAVRAGF
MSMEG_1272|M.smegmatis_MC2_155 CDNNGWVVAALQAAWSAISTTPVPHEDPRSEVFRADHLRLALEAAVRGGG
TH_0049|M.thermoresistible__bu AGKNGWVVAALQGAWSSIVTTPIPVDDPAAGLFRADHLRLALEAAVRGGG
MAB_2353|M.abscessus_ATCC_1997 P---EQIAARLGGGWVGEEALAIGVY----AALAAHDFKDGIRLSVNHSG
:. * ..* . : . : .: .: :*. .
Mvan_1100|M.vanbaalenii_PYR-1 DTDTVAAIAGGLLGAAYGASAVPLEWRTLLHGWPGVRARELVKLSGRIAR
Mflv_5181|M.gilvum_PYR-GCK DTDTVAAIAGGLLGAVHGASAVPRAWRELLHGWPGLDAAELAELAHAAAR
MSMEG_1272|M.smegmatis_MC2_155 DTDTVAAIAGGLLGAAYGASAVPSQWRRLLHGWPGLRTRGLTALADRTVN
TH_0049|M.thermoresistible__bu DTDTVAAIAGGLLGAVHGASAVPAQWRLLLTGWPGLNTRGLVQLATDIVS
MAB_2353|M.abscessus_ATCC_1997 DSDSTGAIAGNILGAMCGTESLPQDW------LDELELREVITTIADDLV
*:*:..****.:*** *:.::* * : :
Mvan_1100|M.vanbaalenii_PYR-1 RGAVDRFDPRYPGY-QVGVMVPHPYDDGVLLAGIGALHELPAGVDAVVSL
Mflv_5181|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1272|M.smegmatis_MC2_155 KGRPVEFNQSYAAGRETPEPVRHPHDDGVWIGIAYSLNRLPSDIDAVVSL
TH_0049|M.thermoresistible__bu GGQAESFDQAYGAYPESALAVRHPHDVDIWIGNAAALHRLPDGVDAVVSL
MAB_2353|M.abscessus_ATCC_1997 GPPGPDWDERYPPR------------------------------------
Mvan_1100|M.vanbaalenii_PYR-1 CRVGDEVVRRDIPHVEVRLIDRPGAHDNPHLDFVMLEAVRAVERFRGEGK
Mflv_5181|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1272|M.smegmatis_MC2_155 CRVADGHIPLRVVHLDVPLLDQEGANPN--LDFVVLDTVRAIEQLRAEGR
TH_0049|M.thermoresistible__bu CRVADEHIPDGATHLDVRLIDRVGDNAN--LDFVLLDTVRAVEQLRAENR
MAB_2353|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_1100|M.vanbaalenii_PYR-1 TVLLHCVEAHSRTPSVAALYGARLRGVGTGEALHAVCGALPDASPNPAFR
Mflv_5181|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_1272|M.smegmatis_MC2_155 TVFVHSAAAQNRAPAVAALYGARRQGLGIDRALREVCAVLPSAQPNPDLR
TH_0049|M.thermoresistible__bu TVYLHCVHAYSRTPTIAALYGARRQGIGIERALDEVCAVLSGANPNPEFR
MAB_2353|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_1100|M.vanbaalenii_PYR-1 EALARFDSAHAAAR
Mflv_5181|M.gilvum_PYR-GCK --------------
MSMEG_1272|M.smegmatis_MC2_155 AALRRLHVVEAGAR
TH_0049|M.thermoresistible__bu DALRRLHSGD----
MAB_2353|M.abscessus_ATCC_1997 --------------