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M. vanbaalenii PYR-1 Mvan_1017 (-)

annotation: glucarate dehydratase
coordinates: 1066865 - 1068202
length: 445

RTPVITDVTVVPIAGHDSMLLNLSGAHGPFFTRNLVIVEDSEGNTGVGEVPGGEPIRRTLQDARGIVTGR
SIGDYHAVLNEMRRTFADRDAGGRGAQTFDLRVTVHAVTAIESALMDLLGQHLEVPVAALLGDGQQRSRV
QALGYLFFVGDRTRTDLAYRSPSDEEPGADDWFTVRHEEAMTPDAVVRLAEAARARYGFADFKLKGGVLP
AADEAKAVIALAERFPDSRITLDPNGGWLLADAIRTCRELKDVLAYAEDPVGPEDGFSGREVMAEFKRAT
GLPTATNMIATDWREMGHAIRSGAVDIPLADPHFWTMTGSVRVAQLCDAWGLTWGSHSNNHFDVSLAMFT
HVAAAAPGDITAIDTHWIWQDGQAITTNPYPIVDGYLSVPDAPGLGVTLDEPAVQAAHALYQREGLGGRD
DAVAMQYLIPGWTFDGKRPALDRG*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_1017--100% (445)glucarate dehydratase
M. vanbaalenii PYR-1Mvan_1029-1e-5632.73% (440) mandelate racemase/muconate lactonizing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. gilvum PYR-GCKMflv_1357-2e-1828.22% (411) mandelate racemase/muconate lactonizing protein
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_6117-0.082.13% (442) glucarate dehydratase
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mvan_1017|M.vanbaalenii_PYR-1       ----MRTPVITDVTVVPIAGHDSMLLNLSGAHGPFFTRNLVIVEDSEGNT
MSMEG_6117|M.smegmatis_MC2_155      MTAHGTTPVVTEMTVIQVAGHDSMLLNLSGAHGPYFTRNLVKLTDSDGNT
Mflv_1357|M.gilvum_PYR-GCK          -------MKITAVDAIPFAIPYTKPLKFASGEVHTAEHVLVRVHTDEGVV
                                             :* : .: .*   :  *:::...     : ** :  .:* .

Mvan_1017|M.vanbaalenii_PYR-1       GVGEVPGGEPIRRTLQDARGIVTGRSIGDYHAVLNEMRRTFADRDAGGRG
MSMEG_6117|M.smegmatis_MC2_155      GVGEVPGGEAIRRTLTDATPLVVGRSIGEYHATLAAIRGAFADRDSGGRG
Mflv_1357|M.gilvum_PYR-GCK          GVAEAPPRPFTYGETQDGILAVIRQIFAPQIVGLTLTEREVVN----ARL
                                    **.*.*          *.   *  : :.   . *   .  ..:    .* 

Mvan_1017|M.vanbaalenii_PYR-1       AQTFDLRVTVHAVTAIESALMDLLGQHLEVPVAALLGDGQQRSRVQALGY
MSMEG_6117|M.smegmatis_MC2_155      AQTFDLRVTVHAVTAVESALLDLMGKHLGVPVAALLGDGQQRNRVQALGY
Mflv_1357|M.gilvum_PYR-GCK          ARTVGN---PTAKAAVDMAIWDALGRSLDLSVSALLGG------------
                                    *:*..      * :*:: *: * :*: * :.*:****.            

Mvan_1017|M.vanbaalenii_PYR-1       LFFVGDRTRTDLAYRSPSDEEPGADDWFTVRHEEAMTPDAVVRLAEAARA
MSMEG_6117|M.smegmatis_MC2_155      LFFVGDRNRTDLPYRAPDDEPAGADEWQRIRHDEALSPEAVVRLAEAARA
Mflv_1357|M.gilvum_PYR-GCK          ---YGDHMRVSHMLG-------------------FDTPDTMVAEAERIRD
                                        **: *..                         :*:::*  **  * 

Mvan_1017|M.vanbaalenii_PYR-1       RYGFADFKLKGGVLPAADEAKAVIALAERFPD-SRITLDPNGGWLLADAI
MSMEG_6117|M.smegmatis_MC2_155      RYGFRDFKLKGGVLPAAEEAKAVTALAERFPD-ARITLDPNGGWLLRDAI
Mflv_1357|M.gilvum_PYR-GCK          EYGISTFKVKVGRRPVTLDTAVVRALRERFGDTVELYVDGNRGWTASESL
                                    .**:  **:* *  *.: :: .* ** *** *  .: :* * **   :::

Mvan_1017|M.vanbaalenii_PYR-1       RTCRELKDVLAYAEDPVGPEDGFSGREVMAEFKRATGLPTATNMIATDWR
MSMEG_6117|M.smegmatis_MC2_155      VTCRQLTDVLAYAEDPVGPEGTFSGREVMAEFKRATGLPTATNMIATDWR
Mflv_1357|M.gilvum_PYR-GCK          RALKDMADLDLLFAEELCPADDVLGRRWLVEHT---EIPFIADESVPTPA
                                     : ::: *:     : : * . . **. :.*..    :*  ::  ..   

Mvan_1017|M.vanbaalenii_PYR-1       EMGHAIRSGAVDIPLADPHFWTMTGSVRVAQLCDAWGLTWGSHSNNHFDV
MSMEG_6117|M.smegmatis_MC2_155      ELGHAIRAGAVDIPLADPHFWTMSGSVRVAAICDAWGLTWGSHSNNHFDV
Mflv_1357|M.gilvum_PYR-GCK          DVTREVLGGSATAISIKTARTGFTGSRRVHHLAEGLGLEVVMG--NQIDG
                                    :: : : .*:.     ..    ::** **  :.:. **       *::* 

Mvan_1017|M.vanbaalenii_PYR-1       SLAMFTHVAAAAPGDITAIDT---HWIWQDGQAITTNPYPIVDGYLSVPD
MSMEG_6117|M.smegmatis_MC2_155      SLAMFTHVAAAAPGDITAIDT---HWIWQDGQRITKQPFEIVDGYLDVPT
Mflv_1357|M.gilvum_PYR-GCK          QLGTACAVAFGAAFELTSRRAGELSNFLDMSDDLLTHPLRIRDGRLHVPP
                                    .*.    ** .*. ::*:  :     : : .: : .:*  * ** * ** 

Mvan_1017|M.vanbaalenii_PYR-1       APGLGVTLDEPAVQAAHALYQREGLGGRDDAVAMQYLIPGWTFDGKRPAL
MSMEG_6117|M.smegmatis_MC2_155      APGLGVELDDDRVAAAHELYLAEGLGARDDSVAMQYLIPGWTFDPKRPAL
Mflv_1357|M.gilvum_PYR-GCK          GPGLGIEIDPDKLDHYRTDH------------------------------
                                    .****: :*   :   :  :                              

Mvan_1017|M.vanbaalenii_PYR-1       DRG
MSMEG_6117|M.smegmatis_MC2_155      QRK
Mflv_1357|M.gilvum_PYR-GCK          ---