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PSNTAAPPQASRRRRLLLAAVTAMVVGSVPTVSFPAAAQVPEFDLQAHRGGRGETTEESLRAFAKSLELG VSTLELDVVLTKDGQPLVWHDPVLQPEKCTDTGPAFAADAQYPYVGKLVHDLTLAQIRTLDCGKLLDDFP DAEVVTANKIATLPEVFGLADSYAADVRFNIETKIEADKPETSAGPREIVDAVLAAARSAGKLDRVEIQS FDWRTLPLVRHLEPSIPLVALWDETTWVPGSPWLAGIDPAVVGDPLTGATMVGAGIVSPGYSIPYGLTPD DPGFALVADRPFIERAHAMGLKVIPWTVNDEDTMRAQIVAGADGIITDYPALLRDVMTQLGLPLPPPYRR H*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0998 | - | - | 100% (352) | glycerophosphoryl diester phosphodiesterase |
| M. vanbaalenii PYR-1 | Mvan_5667 | - | 4e-11 | 25.99% (304) | glycerophosphoryl diester phosphodiesterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3872c | glpQ1 | 7e-09 | 24.91% (285) | glycerophosphoryl diester phosphodiesterase |
| M. gilvum PYR-GCK | Mflv_1140 | - | 8e-13 | 26.71% (292) | glycerophosphodiester phosphodiesterase |
| M. tuberculosis H37Rv | Rv3842c | glpQ1 | 7e-09 | 24.91% (285) | glycerophosphoryl diester phosphodiesterase |
| M. leprae Br4923 | MLBr_00325 | - | 2e-16 | 61.90% (63) | hypothetical protein MLBr_00325 |
| M. abscessus ATCC 19977 | MAB_0573 | - | 1e-130 | 70.13% (308) | putative glycerophosphoryl diester phosphodiesterase precursor |
| M. marinum M | MMAR_5394 | glpQ1 | 3e-09 | 24.83% (286) | glycerophosphoryl diester phosphodiesterase GlpQ1 |
| M. avium 104 | MAV_0576 | - | 1e-108 | 59.76% (333) | glycerophosphoryl diester phosphodiesterase family protein |
| M. smegmatis MC2 155 | MSMEG_6423 | - | 9e-13 | 25.85% (294) | glycerophosphoryl diester phosphodiesterase family protein |
| M. thermoresistible (build 8) | TH_0749 | glpQ1 | 3e-08 | 32.81% (128) | PROBABLE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLPQ1 |
| M. ulcerans Agy99 | MUL_5015 | glpQ1 | 3e-08 | 24.48% (286) | glycerophosphoryl diester phosphodiesterase GlpQ1 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3872c|M.bovis_AF2122/97 ---------------MTWADEVLAG-----------------HPFVVAHR
Rv3842c|M.tuberculosis_H37Rv ---------------MTWADEVLAG-----------------HPFVVAHR
MMAR_5394|M.marinum_M -------------MGMTWADEVIAG-----------------HPFVVAHR
MUL_5015|M.ulcerans_Agy99 ---------------MTWADEVIAG-----------------HPFVVAHR
Mflv_1140|M.gilvum_PYR-GCK ----------------MSSGATLGG-----------------HPFVVAHR
MSMEG_6423|M.smegmatis_MC2_155 ----------MTEADAGADGQAPTGPT---------------HPFVVAHR
TH_0749|M.thermoresistible__bu ---------------METGGEALGR-----------------HPYVVAHR
Mvan_0998|M.vanbaalenii_PYR-1 MPSNTAAPPQASRRRRLLLAAVTAMVVGSVPTVSFPAAAQVPEFDLQAHR
MAB_0573|M.abscessus_ATCC_1997 -----------MKRIAAVLAVTLALVS--------CGDKDTKSFDLQAHR
MAV_0576|M.avium_104 -MSSLGSRWAVAAAVALLMAVLLSAAP---------VYGQPATFDLQAHR
MLBr_00325|M.leprae_Br4923 --------------------------------------------------
Mb3872c|M.bovis_AF2122/97 GASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTST
Rv3842c|M.tuberculosis_H37Rv GASAARPEHTLAAYDLALKEGADGVECDVRLTRDGHLVCVHDRRLDRTST
MMAR_5394|M.marinum_M GASGARPEHTLAAYDLALKQGADGVECDVRLTRDGHLVCVHDRRLDRTST
MUL_5015|M.ulcerans_Agy99 GASGARPEHTLAAYDLALKQGADGVECDVRLTRDGHLVCVHDRRLDRTST
Mflv_1140|M.gilvum_PYR-GCK GASADRPEHTLAAYQLALEEGADAVECDVRLTRDGHLVCVHDRRLDRTSS
MSMEG_6423|M.smegmatis_MC2_155 GASADRPEHTLAAYDLALQEGADGLECDVRLTRDGHLVCVHDRKVDRTST
TH_0749|M.thermoresistible__bu GASADRPEHTLAAYELALEEGADGLECDVRLTRDGQLVCVHDRRVDRTST
Mvan_0998|M.vanbaalenii_PYR-1 GGRGETTEESLRAFAKSLELGVSTLELDVVLTKDGQPLVWHDPVLQPEKC
MAB_0573|M.abscessus_ATCC_1997 GGRGETTEESLRAFAKALELGVSTLELDIVISKDGKPMVWHDPVIDPAKC
MAV_0576|M.avium_104 GGRGETTEESLRAFAKAIQTGVSTLELDIVVTRDGQPLVWHDPTIQADKC
MLBr_00325|M.leprae_Br4923 --------------------------------------------------
Mb3872c|M.bovis_AF2122/97 GAG---------------LVSTMTLAQLRELEYGAWHDSWRPDGSHGDTS
Rv3842c|M.tuberculosis_H37Rv GAG---------------LVSTMTLAQLRELEYGAWHDSWRPDGSHGDTS
MMAR_5394|M.marinum_M GAG---------------LVSTMTLDQLRELEYGAWHDSWRPDGAHGDTS
MUL_5015|M.ulcerans_Agy99 GAG---------------LVSTMTLDQLRELEYGAWHDSRRPDGAHGDTS
Mflv_1140|M.gilvum_PYR-GCK GTG---------------LVSDMTLAQLRELDFGAWHPSRRDDVSGGDTG
MSMEG_6423|M.smegmatis_MC2_155 GTG---------------LVSEMTLAELRKLNFGSWHPSWRADSSGDDTG
TH_0749|M.thermoresistible__bu GSG---------------VISTMTLDELRRLDFGAWHDSWQP--VYGTFG
Mvan_0998|M.vanbaalenii_PYR-1 TDTGPAFAADAQYPYVGKLVHDLTLAQIRTLDCGKLLDDFPDAEVVTANK
MAB_0573|M.abscessus_ATCC_1997 SDTGPVRPGDPQFPYVGKLVKDLTSGQLHTLDCGKLLTDFPRAEVVKNDK
MAV_0576|M.avium_104 SDTGPAFPGDPGYPYVGKLVHQLTVAQIHTLDCGHRLKEFPDAEVVRGNK
MLBr_00325|M.leprae_Br4923 --------------------------------------------MLRGNK
Mb3872c|M.bovis_AF2122/97 LLTLDALVSLVLDWHRP-VKIFVETKHPVRYGSLVENKLLALLHRFGIAA
Rv3842c|M.tuberculosis_H37Rv LLTLDALVSLVLDWHRP-VKIFVETKHPVRYGSLVENKLLALLHRFGIAA
MMAR_5394|M.marinum_M LLTLDALISLVLDWKRP-VKVFIETKHPVRYGSLVESKVLALLQRFGIAQ
MUL_5015|M.ulcerans_Agy99 LLTLDALISLVLDWKRP-VKVFIETKHPVRYGSLVESKVLALLQRFGIAQ
Mflv_1140|M.gilvum_PYR-GCK LLTLDDLVSLVMDWNRP-VKMFIETKHPVRYGGLVESKVLALLHRYGIAS
MSMEG_6423|M.smegmatis_MC2_155 VLTLDELVRMALDWNRP-VKLFIETKHPVRYGALVENKLLALLHRYGIAA
TH_0749|M.thermoresistible__bu LLTLEELIGLVLGWKRP-VKLFIETKHPVRYGGLVESKVLAMLHRFGIAS
Mvan_0998|M.vanbaalenii_PYR-1 IATLPEVFGLADSYAAD-VRFNIETKIEADK-PETSAGPREIVDAVLAAA
MAB_0573|M.abscessus_ATCC_1997 IAQLSDVFALADSYHAD-VRFNIETKVEAAE-PQKSAEPQRFVDIILETI
MAV_0576|M.avium_104 IATLPEVFAVADSHRADAIRYNIETKVEPDD-TGASAPPQEFVDVILAAV
MLBr_00325|M.leprae_Br4923 IVVLPEVFALTDYYLAD-VRFNIETKVAADR-PAVSVFSQEFVDVVLAVV
: * :. :. :: :*** . ::. .
Mb3872c|M.bovis_AF2122/97 PASADRSRAVVMSFSAAAVWRIRRAAPLLPTVLLGKTPRYLTSS------
Rv3842c|M.tuberculosis_H37Rv PASADRSRAVVMSFSAAAVWRIRRAAPLLPTVLLGKTPRYLTSS------
MMAR_5394|M.marinum_M PASADRSRAVVMSFSAAAVWRIRRAAPLLPTVLLGKTARYLASG------
MUL_5015|M.ulcerans_Agy99 PASADRSRAAAMSFSAAAVWRIRRAAPLLPTVLLGKTARYLASG------
Mflv_1140|M.gilvum_PYR-GCK PASADMARAVVMSFSAGAVWRIRRAAPMLPTVLLGETSRYLGGG------
MSMEG_6423|M.smegmatis_MC2_155 PASADMARAVVMSFSAAAVWRIRRAAPMLPTVLLGETSRYLGGS------
TH_0749|M.thermoresistible__bu PPSARLSRAVIMX-------GRRRSTTWRPA-------------------
Mvan_0998|M.vanbaalenii_PYR-1 RSAGKLDRVEIQSFDWRTLPLVRHLEPSIPLVALWDETTWVPGSPWLAGI
MAB_0573|M.abscessus_ATCC_1997 RAAGKLDKVEIQSFDWRTLPMTKRAEPGIPLVALWDETTWYPGSPWLGGV
MAV_0576|M.avium_104 RSADKLARVEIQSFDWRTLPLVRRAEPSIPLVALYDER------------
MLBr_00325|M.leprae_Br4923 RSVGKVDRVASP-----------------------GER------------
. :.
Mb3872c|M.bovis_AF2122/97 -----AATAVGATAVGPSLPALK-----------------EYPQLVDRSA
Rv3842c|M.tuberculosis_H37Rv -----AATAVGATAVGPSLPALK-----------------EYPQLVDRSA
MMAR_5394|M.marinum_M -----AASAVGATAVGPSLAVLR-----------------EYPQLVDRAA
MUL_5015|M.ulcerans_Agy99 -----AASAVGATAVGPSLAVLR-----------------EYPQLVDRAA
Mflv_1140|M.gilvum_PYR-GCK -----AATTVGATAVGPSIATLR-----------------EHPELVDRAA
MSMEG_6423|M.smegmatis_MC2_155 -----AATTVGATAVGPSIATLR-----------------EHPELVDRAA
TH_0749|M.thermoresistible__bu --------------------------------------------------
Mvan_0998|M.vanbaalenii_PYR-1 DPAVVGDPLTGATMVGAGIVSPGYSIPYGLTPDDPGFALVADRPFIERAH
MAB_0573|M.abscessus_ATCC_1997 DPAIVSDPIDGAKQVGATILSPGYTVPYGGKVGDPGFTLVADKKFIDKAH
MAV_0576|M.avium_104 ---AAGDPVLGARAAGADIVSP-------------DYRLVTGKPYVDRAH
MLBr_00325|M.leprae_Br4923 -------PADGAS-------------------------------------
Mb3872c|M.bovis_AF2122/97 AQGRAVYCWNVDEYEDIDFCREVGVAWIGTHHPGRTKAWLEDGR---ANG
Rv3842c|M.tuberculosis_H37Rv AQGRAVYCWNVDEYEDIDFCREVGVAWIGTHHPGRTKAWLEDGR---ANG
MMAR_5394|M.marinum_M AQGRAVYCWGVDEYEDFDFCRDVGVAWMATDHPGRAKAWLQHGRPGVSSG
MUL_5015|M.ulcerans_Agy99 AQGRAVYCWGVDEYEDIDFCRDVGVAWMASDHPGRAKAWLQHGRPGVSSG
Mflv_1140|M.gilvum_PYR-GCK AQGRALYCWTVDHYEDVQYCADLGVAWIATNHPGRTKAWLQNGL----TG
MSMEG_6423|M.smegmatis_MC2_155 AQGRALYCWTVDHYEDVRFCRDVGVAWIATNHPGRTKDWLQNGL----TG
TH_0749|M.thermoresistible__bu --------------------------------------------------
Mvan_0998|M.vanbaalenii_PYR-1 AMGLKVIPWTVNDEDTMRAQIVAGADGIITDYPALLRDVMTQLGLPLPPP
MAB_0573|M.abscessus_ATCC_1997 RLGLKVIPWTINDAETMKAQIDAGADGIISDYPTTLRKVMAESDLPLPPA
MAV_0576|M.avium_104 ALGLKVIPWTVDDAENMRRQIDYGVDGLITDFPTLARGVLAELGVPLPPA
MLBr_00325|M.leprae_Br4923 --GLAVY--TVG--------------GLMG--------------------
Mb3872c|M.bovis_AF2122/97 TTR----
Rv3842c|M.tuberculosis_H37Rv TTR----
MMAR_5394|M.marinum_M PAAPPEA
MUL_5015|M.ulcerans_Agy99 PAAPPEA
Mflv_1140|M.gilvum_PYR-GCK AGRD---
MSMEG_6423|M.smegmatis_MC2_155 AGRD---
TH_0749|M.thermoresistible__bu -------
Mvan_0998|M.vanbaalenii_PYR-1 YRRH---
MAB_0573|M.abscessus_ATCC_1997 YHR----
MAV_0576|M.avium_104 VPG----
MLBr_00325|M.leprae_Br4923 -------