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M. vanbaalenii PYR-1 Mvan_0755 (-)

annotation: membrane-flanked domain-containing protein
coordinates: 796353 - 797795
length: 480

VTPEWSRLSPRMLLVHPVHEVVRQIPVLVGSLVLGSATGNPLWAVAGVALVIAYGLARWFTTTYRIGADD
VQLRTGVLQRNVLSVPRNRIRSVSTDARLLHRLLGLTVVRVSTGQEATGDTSFELDAVPVAEVARLRAIL
LAESLVPAGSAEPTRVLARWQPSWLRYSPLTFTGLLMIAAALGLLSHPGVFGALRDSGLVRKGERAAESL
GVLGAVTVVVAVVLTASVALSVLQSLLSYGNLVLRRDAEVLHLSHGLLRVREHTFDMRRLRGGTLREPLL
VRLFGGARLDAVMTGVAGAGEASQLLPPCPRGTAEAVLADLIDRPDAVTGPLTAHGPVATRRRWTRAMLA
PAAVVVGLAVVSVVTDVPGSAWLVPAVLTVGCGFLAFDRARSLGHRVGGGWLVARAGSLQRRRDCVAAAG
IVGWTVRQSLPQRRAGVATLVAATAAGVKRYEVIDVPADLAWSIAAATSPWVGATAWARR
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_0755--100% (480)membrane-flanked domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1258c-1e-17565.07% (481) hypothetical protein Mb1258c
M. gilvum PYR-GCKMflv_0149-0.076.60% (483) membrane-flanked domain-containing protein
M. tuberculosis H37RvRv1226c-1e-17464.86% (481) hypothetical protein Rv1226c
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_1270-3e-2426.99% (452) hypothetical protein MAB_1270
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_0865-0.067.62% (488) membrane flanked domain-containing protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb1258c|M.bovis_AF2122/97           MTDRP------HDWHRLSPRMLLVHPVHEMLRQLPVLIGSVVLGSATGNP
Rv1226c|M.tuberculosis_H37Rv        MTDRP------HDWHRLSPRMLLVHPVHEMLRQLPVLIGSVVLGSATGNP
Mvan_0755|M.vanbaalenii_PYR-1       MTP---------EWSRLSPRMLLVHPVHEVVRQIPVLVGSLVLGSATGNP
Mflv_0149|M.gilvum_PYR-GCK          MTPQA-------DWLRLSPRMLVVHPVHEVVRQIPVLIGSLVVGSATGNP
MSMEG_0865|M.smegmatis_MC2_155      MTAPPQPPGAGPQWQRLSPRMLLVHPVHEVLQQIPLLVGSVVLGSATGNP
MAB_1270|M.abscessus_ATCC_1997      ------------MTLRRSARWILREFIETLKIGWAGLALVLVN---ESFL
                                                   * *.* :: . :. :    . *   :*     .  

Mb1258c|M.bovis_AF2122/97           VWPLAALGVTVVFGVLRWFFTTYRIDDENVSLRTGILSRRAVSVPRNRIR
Rv1226c|M.tuberculosis_H37Rv        VWPLAALGVTVVFGVLRWFFTTYRIDDENVSLRTGILSRRAVSVPRNRIR
Mvan_0755|M.vanbaalenii_PYR-1       LWAVAGVALVIAYGLARWFTTTYRIGADDVQLRTGVLQRNVLSVPRNRIR
Mflv_0149|M.gilvum_PYR-GCK          LWAVVGVVLIVGYGLARWFTTTYRIGADEVQLRTGVLQRTVLSVPRNRIR
MSMEG_0865|M.smegmatis_MC2_155      LWTVAAIVLTILFGLARWFTTTYRIEPNEVQLRTGVLQRKVLAVPRNRIR
MAB_1270|M.abscessus_ATCC_1997      LLFLAYLVLVVLLKTWAWRRTTIQVGGDAVVLEVRGVTTRRESVARSAVE
                                    :  :. : : :      *  ** ::  : * *..  :     :*.*. :.

Mb1258c|M.bovis_AF2122/97           SVQTEARLLHRLLGLTVLRVGTGQEARGEAAFELDAVDSARVPRLRALLL
Rv1226c|M.tuberculosis_H37Rv        SVQTEARLLHRLLGLTVLRVGTGQEARGEAAFELDAVDSARVPRLRALLL
Mvan_0755|M.vanbaalenii_PYR-1       SVSTDARLLHRLLGLTVVRVSTGQEATGDTSFELDAVPVAEVARLRAILL
Mflv_0149|M.gilvum_PYR-GCK          SVSTDARLLHRLLGLTVLKVSTGQEATGDGVFELDAVPAAEVGRLRAVLL
MSMEG_0865|M.smegmatis_MC2_155      SVSTDARLLHRVMGLTVLRISTGQEAKGDAEFALDAVEAGQVPRLRAILL
MAB_1270|M.abscessus_ATCC_1997      TLVVSAEMLDRLCGLQTLQLTTNDDSN---NLVLDGLSPQSVRDIGASLE
                                    :: ..*.:*.*: ** .::: *.:::     : **.:    *  : * * 

Mb1258c|M.bovis_AF2122/97           AESLAP----VEPTGRVLARWQSSWLRYAPLSFSGLVMIGAVIGLGYQTG
Rv1226c|M.tuberculosis_H37Rv        AESLAP----VEPTGRVLARWQSSWLRYAPLSFSGLVMIGAVIGLGYQTG
Mvan_0755|M.vanbaalenii_PYR-1       AESLVP-AGSAEP-TRVLARWQPSWLRYSPLTFTGLLMIAAALGLLSHPG
Mflv_0149|M.gilvum_PYR-GCK          AESLAA-PDVARAGGRELARWQPSWLRYSPLTFTGLITIVAALGVISQTG
MSMEG_0865|M.smegmatis_MC2_155      ADLADASPEEHVPAGRELARWQPAWLRYSPLSFTGLAMILAAFGIVYQAG
MAB_1270|M.abscessus_ATCC_1997      TEVSEK-----ASDVRVIAAFRPGWFGYSLLTPIGWAGVVGVAFLANRIG
                                    ::          .  * :* ::..*: *: *:  *   : ..  :  : *

Mb1258c|M.bovis_AF2122/97           LAVRLPESGFARSAVDAAQRAGVVLVVAVTVLLVVGVSALLAVLFSWLTY
Rv1226c|M.tuberculosis_H37Rv        LAVRLPESGFARSAVDAAQRAGVVLVVAVTVLLVVGVSALLAVLFSWLTY
Mvan_0755|M.vanbaalenii_PYR-1       VFGALRDSGLVRKGERAAESLGVLGAVTVVVAVVLTASVALSVLQSLLSY
Mflv_0149|M.gilvum_PYR-GCK          VLGALQDSQIVRAGEQATDRVGVAVAVALGAGAVLVASVVLSVTQSLISY
MSMEG_0865|M.smegmatis_MC2_155      AGALMRDSAFAQSGLDAAERLGVAVSIAIVVGAVLVASVVLSVLRSLLTY
MAB_1270|M.abscessus_ATCC_1997      DRFVSQFDGLSAQARAALAHIATPLLIVLG----VASGVAIVLFSYAARY
                                           . :   .  *    ..   :.:     :  .. : :      *

Mb1258c|M.bovis_AF2122/97           GNLLLRR---GGSGQEGVLHLRHGLLRVREHTYDMRRLRGATLREPLLVR
Rv1226c|M.tuberculosis_H37Rv        GNLLLRR---GGSGQEGVLHLRHGLLRVREHTYDMRRLRGATLREPLLVR
Mvan_0755|M.vanbaalenii_PYR-1       GNLVLRR-------DAEVLHLSHGLLRVREHTFDMRRLRGGTLREPLLVR
Mflv_0149|M.gilvum_PYR-GCK          GNLVLRR-------DAEVLHLSHGLLRVRERTFDMRRLRGGTLREPLLVR
MSMEG_0865|M.smegmatis_MC2_155      GNLVLTRR--DGPGGDGVLHLQHGLLRVREHTYDMRRLRGGTLREPLLVR
MAB_1270|M.abscessus_ATCC_1997      GGFRLEESPGTGSGEDPLLIYRRGLLETKAITFARSRIRGIRLTEPIPLR
                                    *.: * .          :*   :***..:  *:   *:**  * **: :*

Mb1258c|M.bovis_AF2122/97           LLRGARLDAVMTGVHGEGQSSMLLPPCPFETATAVLTDLIDNT-------
Rv1226c|M.tuberculosis_H37Rv        LLRGARLDAVMTGVHGEGQSSMLLPPCPFETATAVLTDLIDNT-------
Mvan_0755|M.vanbaalenii_PYR-1       LFGGARLDAVMTGVAGAGEASQLLPPCPRGTAEAVLADLIDRP-------
Mflv_0149|M.gilvum_PYR-GCK          LFGGARLDAVMTGVTGAGEASQLLPPCPRATAESVLIDLIEQP-------
MSMEG_0865|M.smegmatis_MC2_155      VFGGARLDAVMTGIGGEGEASLLLPPCPAATARGVLTALIGRP-------
MAB_1270|M.abscessus_ATCC_1997      WAKGARLHAEIVGH----KDIELLPPTARTFALHIARDVLSHHGLDAVAA
                                       ****.* :.*     :   **** .   *  :   :: .        

Mb1258c|M.bovis_AF2122/97           DAAAGPLRRHGPAAARRRWTRALLVPTLAGVALIAAAPILGVPGWAWTLW
Rv1226c|M.tuberculosis_H37Rv        DAAAGPLRRHGPAAARRRWTRALLVPTLAGVALIAAAPILGVPGWAWTLW
Mvan_0755|M.vanbaalenii_PYR-1       DAVTGPLTAHGPVATRRRWTRAMLAPAAVVVGLAVVSVVTDVPGSAWLVP
Mflv_0149|M.gilvum_PYR-GCK          AAVTGPLTGHGRAAMRRRWTRAMTVPVLLAAALLVWAVFDAVPPWAWAAP
MSMEG_0865|M.smegmatis_MC2_155      DAVSGPLRPHGPAATRRRWTRALVLPVIALPVLAVVG----VPVWAWVLW
MAB_1270|M.abscessus_ATCC_1997      VSAGGRLAAHGRAARRVSLQESATVPLVLIVAAAGAAVINAESSFLVILA
                                     :. * *  ** .* *    .:   *          .     .       

Mb1258c|M.bovis_AF2122/97           AVLTAG----CAGLAVDRVRSLGHRVADGWLVARAG-SLQRRRDCIACTG
Rv1226c|M.tuberculosis_H37Rv        AVLTAG----CAGLAVDRVRSLGHRVADGWLVARAG-SLQRRRDCIACTG
Mvan_0755|M.vanbaalenii_PYR-1       AVLTVG----CGFLAFDRARSLGHRVGGGWLVARAG-SLQRRRDCVAAAG
Mflv_0149|M.gilvum_PYR-GCK          AATAVA----GALLAADRVRALGHRIGDGWLVARAG-SLQRRRDCIAAAG
MSMEG_0865|M.smegmatis_MC2_155      ALVTVA----AALLAADRSRALGHRVDGDWLVAQAG-SVERRRDCLHTDG
MAB_1270|M.abscessus_ATCC_1997      LVLLIVRLCYTWIVSGRRASAWGRRSNQPLVLAQSHPRLARNLSITTCDS
                                                 ::  *  : *:*     ::*::   : *. .     .

Mb1258c|M.bovis_AF2122/97           IIGWTVRQTLFQRRAGVATLVAATAAGRKGYQVLDVPAELAWSVAGAASP
Rv1226c|M.tuberculosis_H37Rv        IIGWTVRQTLFQRRAGVATLVAATVAGRKGYQVLDVPAELAWSVAGAASP
Mvan_0755|M.vanbaalenii_PYR-1       IVGWTVRQSLPQRRAGVATLVAATAAGVKRYEVIDVPADLAWSIAAATSP
Mflv_0149|M.gilvum_PYR-GCK          IVGWTVRQTLFQRRAGVATLIAATAAGVKRYELIDVPADAAWAIAGATSP
MSMEG_0865|M.smegmatis_MC2_155      IIGWTVRQTLLQRRAGVATLIAATAAGQKRYEVIDVPAGQAWAIAAAGTP
MAB_1270|M.abscessus_ATCC_1997      ALGVRTRQSWRQRRAGVADLRIRSNAGDGALAVDCLPVIAATNLAVCLCP
                                     :*  .**:  ******* *   : **     :  :*.  *  :* .  *

Mb1258c|M.bovis_AF2122/97           WVADSVWLRHGS------------------------
Rv1226c|M.tuberculosis_H37Rv        WVADSVWLRHGS------------------------
Mvan_0755|M.vanbaalenii_PYR-1       WVGATAWARR--------------------------
Mflv_0149|M.gilvum_PYR-GCK          WLAATGWARR--------------------------
MSMEG_0865|M.smegmatis_MC2_155      WIADSVWAHTPVGSDLR-------------------
MAB_1270|M.abscessus_ATCC_1997      VAATFARPVSPPADPEHAVARFERFGTLHHGMGMTT
                                      .