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MTAPPQPPGAGPQWQRLSPRMLLVHPVHEVLQQIPLLVGSVVLGSATGNPLWTVAAIVLTILFGLARWFT TTYRIEPNEVQLRTGVLQRKVLAVPRNRIRSVSTDARLLHRVMGLTVLRISTGQEAKGDAEFALDAVEAG QVPRLRAILLADLADASPEEHVPAGRELARWQPAWLRYSPLSFTGLAMILAAFGIVYQAGAGALMRDSAF AQSGLDAAERLGVAVSIAIVVGAVLVASVVLSVLRSLLTYGNLVLTRRDGPGGDGVLHLQHGLLRVREHT YDMRRLRGGTLREPLLVRVFGGARLDAVMTGIGGEGEASLLLPPCPAATARGVLTALIGRPDAVSGPLRP HGPAATRRRWTRALVLPVIALPVLAVVGVPVWAWVLWALVTVAAALLAADRSRALGHRVDGDWLVAQAGS VERRRDCLHTDGIIGWTVRQTLLQRRAGVATLIAATAAGQKRYEVIDVPAGQAWAIAAAGTPWIADSVWA HTPVGSDLR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0865 | - | - | 100% (499) | membrane flanked domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1258c | - | 1e-179 | 64.17% (480) | hypothetical protein Mb1258c |
| M. gilvum PYR-GCK | Mflv_0149 | - | 1e-180 | 68.19% (481) | membrane-flanked domain-containing protein |
| M. tuberculosis H37Rv | Rv1226c | - | 1e-179 | 63.96% (480) | hypothetical protein Rv1226c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1270 | - | 3e-23 | 27.88% (452) | hypothetical protein MAB_1270 |
| M. marinum M | MMAR_1258 | - | 4e-05 | 27.17% (173) | hypothetical protein MMAR_1258 |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_2630 | - | 2e-05 | 27.17% (173) | hypothetical protein MUL_2630 |
| M. vanbaalenii PYR-1 | Mvan_0755 | - | 0.0 | 67.62% (488) | membrane-flanked domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0149|M.gilvum_PYR-GCK MTPQA-------DWLRLSPRMLVVHPVHEVVRQIPVLIGSLVVGSATGNP
Mvan_0755|M.vanbaalenii_PYR-1 MTP---------EWSRLSPRMLLVHPVHEVVRQIPVLVGSLVLGSATGNP
MSMEG_0865|M.smegmatis_MC2_155 MTAPPQPPGAGPQWQRLSPRMLLVHPVHEVLQQIPLLVGSVVLGSATGNP
Mb1258c|M.bovis_AF2122/97 MTDRP------HDWHRLSPRMLLVHPVHEMLRQLPVLIGSVVLGSATGNP
Rv1226c|M.tuberculosis_H37Rv MTDRP------HDWHRLSPRMLLVHPVHEMLRQLPVLIGSVVLGSATGNP
MMAR_1258|M.marinum_M --------------------------------------------------
MUL_2630|M.ulcerans_Agy99 --------------------------------------------------
MAB_1270|M.abscessus_ATCC_1997 ------------MTLRRSARWILREFIETLKIGWAGLALVLVN---ESFL
Mflv_0149|M.gilvum_PYR-GCK LWAVVGVVLIVGYGLARWFTTTYRIGADEVQLRTGVLQRTVLSVPRNRIR
Mvan_0755|M.vanbaalenii_PYR-1 LWAVAGVALVIAYGLARWFTTTYRIGADDVQLRTGVLQRNVLSVPRNRIR
MSMEG_0865|M.smegmatis_MC2_155 LWTVAAIVLTILFGLARWFTTTYRIEPNEVQLRTGVLQRKVLAVPRNRIR
Mb1258c|M.bovis_AF2122/97 VWPLAALGVTVVFGVLRWFFTTYRIDDENVSLRTGILSRRAVSVPRNRIR
Rv1226c|M.tuberculosis_H37Rv VWPLAALGVTVVFGVLRWFFTTYRIDDENVSLRTGILSRRAVSVPRNRIR
MMAR_1258|M.marinum_M -----------------------------------------MGYPDN--A
MUL_2630|M.ulcerans_Agy99 -----------------------------------------MGYPDN--A
MAB_1270|M.abscessus_ATCC_1997 LLFLAYLVLVVLLKTWAWRRTTIQVGGDAVVLEVRGVTTRRESVARSAVE
. . .
Mflv_0149|M.gilvum_PYR-GCK SVSTDARLLHRLLGLTVLKVSTGQEATGDGVFELDAVPAAEVGRLRAVLL
Mvan_0755|M.vanbaalenii_PYR-1 SVSTDARLLHRLLGLTVVRVSTGQEATGDTSFELDAVPVAEVARLRAILL
MSMEG_0865|M.smegmatis_MC2_155 SVSTDARLLHRVMGLTVLRISTGQEAKGDAEFALDAVEAGQVPRLRAILL
Mb1258c|M.bovis_AF2122/97 SVQTEARLLHRLLGLTVLRVGTGQEARGEAAFELDAVDSARVPRLRALLL
Rv1226c|M.tuberculosis_H37Rv SVQTEARLLHRLLGLTVLRVGTGQEARGEAAFELDAVDSARVPRLRALLL
MMAR_1258|M.marinum_M MAAGEQVVLHR---------------------------------------
MUL_2630|M.ulcerans_Agy99 MAAGEQVVLHR---------------------------------------
MAB_1270|M.abscessus_ATCC_1997 TLVVSAEMLDRLCGLQTLQLTTNDDSNNLVLDGLSPQSVRDIGASLETEV
. :*.*
Mflv_0149|M.gilvum_PYR-GCK AESLAA-PDVARAGGRELARWQPSWLRYSPLTFTGLITIVAALGVISQTG
Mvan_0755|M.vanbaalenii_PYR-1 AESLVP-AGSAEP-TRVLARWQPSWLRYSPLTFTGLLMIAAALGLLSHPG
MSMEG_0865|M.smegmatis_MC2_155 ADLADASPEEHVPAGRELARWQPAWLRYSPLSFTGLAMILAAFGIVYQAG
Mb1258c|M.bovis_AF2122/97 AESLAP----VEPTGRVLARWQSSWLRYAPLSFSGLVMIGAVIGLGYQTG
Rv1226c|M.tuberculosis_H37Rv AESLAP----VEPTGRVLARWQSSWLRYAPLSFSGLVMIGAVIGLGYQTG
MMAR_1258|M.marinum_M ---------------------HPHWTR----------LVWPVVVLILITG
MUL_2630|M.ulcerans_Agy99 ---------------------HPHWAR----------LVWPVVVLILITG
MAB_1270|M.abscessus_ATCC_1997 SEKASD--------VRVIAAFRPGWFGYSLLTPIGWAGVVGVAFLANRIG
:. * : . : *
Mflv_0149|M.gilvum_PYR-GCK VLGALQDSQIVRAGEQATDRVGVAVAVALGAGAVLVASVVLSVTQSLISY
Mvan_0755|M.vanbaalenii_PYR-1 VFGALRDSGLVRKGERAAESLGVLGAVTVVVAVVLTASVALSVLQSLLSY
MSMEG_0865|M.smegmatis_MC2_155 AGALMRDSAFAQSGLDAAERLGVAVSIAIVVGAVLVASVVLSVLRSLLTY
Mb1258c|M.bovis_AF2122/97 LAVRLPESGFARSAVDAAQRAGVVLVVAVTVLLVVGVSALLAVLFSWLTY
Rv1226c|M.tuberculosis_H37Rv LAVRLPESGFARSAVDAAQRAGVVLVVAVTVLLVVGVSALLAVLFSWLTY
MMAR_1258|M.marinum_M LAALG--SGFVNSTQWQQLAKNIIHGVIWGIWLVIVGWLTLWPFLSWLTT
MUL_2630|M.ulcerans_Agy99 LAALG--SGFVNSTQWQQLAKNIIHGVIWGIWLVIVGWLTLWPFLSWLTT
MAB_1270|M.abscessus_ATCC_1997 DRFVSQFDGLSAQAR--AALAHIATPLLIVLGVASGVAIVLFSYAARYGG
. : : : . * :
Mflv_0149|M.gilvum_PYR-GCK GNLVLRR-----DAEVLHLSHGLLRVRERTFDMRRLRGGTLREPLLVRLF
Mvan_0755|M.vanbaalenii_PYR-1 GNLVLRR-----DAEVLHLSHGLLRVREHTFDMRRLRGGTLREPLLVRLF
MSMEG_0865|M.smegmatis_MC2_155 GNLVLTRRDGPGGDGVLHLQHGLLRVREHTYDMRRLRGGTLREPLLVRVF
Mb1258c|M.bovis_AF2122/97 GNLLLRR-GGSGQEGVLHLRHGLLRVREHTYDMRRLRGATLREPLLVRLL
Rv1226c|M.tuberculosis_H37Rv GNLLLRR-GGSGQEGVLHLRHGLLRVREHTYDMRRLRGATLREPLLVRLL
MMAR_1258|M.marinum_M HFVVTNR--------RVMYRQGVLTRSGIDIPLARINSVEFRDRIFERML
MUL_2630|M.ulcerans_Agy99 HFVVTNR--------RVMYRQGVLTRSGIDIPLARINSVEFRDRIFERML
MAB_1270|M.abscessus_ATCC_1997 FRLEESPGTGSGEDPLLIYRRGLLETKAITFARSRIRGIRLTEPIPLRWA
: : :*:* *:.. : : : *
Mflv_0149|M.gilvum_PYR-GCK GGARLDAVMTGVTGAGEASQLLPPCPRATAESVLIDL-IEQPAAV--TGP
Mvan_0755|M.vanbaalenii_PYR-1 GGARLDAVMTGVAGAGEASQLLPPCPRGTAEAVLADL-IDRPDAV--TGP
MSMEG_0865|M.smegmatis_MC2_155 GGARLDAVMTGIGGEGEASLLLPPCPAATARGVLTAL-IGRPDAV--SGP
Mb1258c|M.bovis_AF2122/97 RGARLDAVMTGVHGEGQSSMLLPPCPFETATAVLTDL-IDNTDAA--AGP
Rv1226c|M.tuberculosis_H37Rv RGARLDAVMTGVHGEGQSSMLLPPCPFETATAVLTDL-IDNTDAA--AGP
MMAR_1258|M.marinum_M RTG---TLIIESASQDPLEFYNIPRLREVHALLYHEV-FDTLGSE--EAP
MUL_2630|M.ulcerans_Agy99 RTG---TLIIESASQDPLEFYNIPRLREVHALLYHEV-FDTLGSE--EAP
MAB_1270|M.abscessus_ATCC_1997 KGARLHAEIVGHKDIELLPPTARTFALHIARDVLSHHGLDAVAAVSAGGR
. : : . . : : : .
Mflv_0149|M.gilvum_PYR-GCK LTGHGRAAMRRRWTRAMTVPVLLAAALLVWAVFDAVPPWAWAAPAATAVA
Mvan_0755|M.vanbaalenii_PYR-1 LTAHGPVATRRRWTRAMLAPAAVVVGLAVVSVVTDVPGSAWLVPAVLTVG
MSMEG_0865|M.smegmatis_MC2_155 LRPHGPAATRRRWTRALVLPVIALPVLAVVG----VPVWAWVLWALVTVA
Mb1258c|M.bovis_AF2122/97 LRRHGPAAARRRWTRALLVPTLAGVALIAAAPILGVPGWAWTLWAVLTAG
Rv1226c|M.tuberculosis_H37Rv LRRHGPAAARRRWTRALLVPTLAGVALIAAAPILGVPGWAWTLWAVLTAG
MMAR_1258|M.marinum_M S-------------------------------------------------
MUL_2630|M.ulcerans_Agy99 S-------------------------------------------------
MAB_1270|M.abscessus_ATCC_1997 LAAHGRAARRVSLQESATVPLVLIVAAAGAAVINAESSFLVILALVLLIV
Mflv_0149|M.gilvum_PYR-GCK ----GALLAADRVRALGHRIGDGWLVARAG-SLQRRRDCIAAAGIVGWTV
Mvan_0755|M.vanbaalenii_PYR-1 ----CGFLAFDRARSLGHRVGGGWLVARAG-SLQRRRDCVAAAGIVGWTV
MSMEG_0865|M.smegmatis_MC2_155 ----AALLAADRSRALGHRVDGDWLVAQAG-SVERRRDCLHTDGIIGWTV
Mb1258c|M.bovis_AF2122/97 ----CAGLAVDRVRSLGHRVADGWLVARAG-SLQRRRDCIACTGIIGWTV
Rv1226c|M.tuberculosis_H37Rv ----CAGLAVDRVRSLGHRVADGWLVARAG-SLQRRRDCIACTGIIGWTV
MMAR_1258|M.marinum_M --------------------------------------------------
MUL_2630|M.ulcerans_Agy99 --------------------------------------------------
MAB_1270|M.abscessus_ATCC_1997 RLCYTWIVSGRRASAWGRRSNQPLVLAQSHPRLARNLSITTCDSALGVRT
Mflv_0149|M.gilvum_PYR-GCK RQTLFQRRAGVATLIAATAAGVKRYELIDVPADAAWAIAGATSPWLAATG
Mvan_0755|M.vanbaalenii_PYR-1 RQSLPQRRAGVATLVAATAAGVKRYEVIDVPADLAWSIAAATSPWVGATA
MSMEG_0865|M.smegmatis_MC2_155 RQTLLQRRAGVATLIAATAAGQKRYEVIDVPAGQAWAIAAAGTPWIADSV
Mb1258c|M.bovis_AF2122/97 RQTLFQRRAGVATLVAATAAGRKGYQVLDVPAELAWSVAGAASPWVADSV
Rv1226c|M.tuberculosis_H37Rv RQTLFQRRAGVATLVAATVAGRKGYQVLDVPAELAWSVAGAASPWVADSV
MMAR_1258|M.marinum_M --------------------------------------------------
MUL_2630|M.ulcerans_Agy99 --------------------------------------------------
MAB_1270|M.abscessus_ATCC_1997 RQSWRQRRAGVADLRIRSNAGDGALAVDCLPVIAATNLAVCLCPVAATFA
Mflv_0149|M.gilvum_PYR-GCK WARR--------------------------
Mvan_0755|M.vanbaalenii_PYR-1 WARR--------------------------
MSMEG_0865|M.smegmatis_MC2_155 WAHTPVGSDLR-------------------
Mb1258c|M.bovis_AF2122/97 WLRHGS------------------------
Rv1226c|M.tuberculosis_H37Rv WLRHGS------------------------
MMAR_1258|M.marinum_M ------------------------------
MUL_2630|M.ulcerans_Agy99 ------------------------------
MAB_1270|M.abscessus_ATCC_1997 RPVSPPADPEHAVARFERFGTLHHGMGMTT