For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TSRRWALWLWTLGAGACITLGAGTGVAAADTETSGGDGPSSQSDDRDASEASSHGAPDQGTGETPDPNAG DGVDADDSSDPATVPASVELADDVVRDADDEAAQEADAAEEVDADTEADTDVDTAADTAAEAEPAAESGS GSGSGSASTVVDETPAQPAAADAEPVRATAPEAANVAPAPVTGVKTGRAKLTIPVGPHDYRTRADWYLPT QADGSVAATGVIWLQHGFLGNKASLSKLAQTLSQQTNSIVVAPNLSSFPLACAGCWINGVPMQEAVAAMF LGDRTSLNASANTAGYLGTLPQDFVMSGQSAGGGFATAVGGYYTEDPGNNGSLRGVMMFDGFSFGGVLTK SLAKLDDPFIPVYQIAAPPQPWNSSGASTKELVAARPGQFVGVTLAGGSHADALIGGNALFDFFAQLVAG FSPPGNTAAVYTLATGWINDMYQGLGPNDGTGIYGDPDQYIVMGDTAAIVLAPPPVVDIDRYLGTWYEVG SVKQFFSIGLVNTKAVYSLNPDASIKVENSGNYFFNNGPESSIVGSALPVDPTNNKLNVRFFGPPSARPP GNYWIVDLDPDYQWAVVTDPTGLSGFLLSRDPVVSADFYQELLDRASVNGVKGWITRTRQPAANQTQL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0445 | - | - | 100% (629) | Lipocalin family protein |
| M. vanbaalenii PYR-1 | Mvan_1256 | - | 1e-60 | 33.01% (518) | hypothetical protein Mvan_1256 |
| M. vanbaalenii PYR-1 | Mvan_1255 | - | 6e-58 | 32.75% (513) | hypothetical protein Mvan_1255 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_0299 | - | 0.0 | 64.90% (641) | Lipocalin family protein |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0869c | - | 4e-05 | 29.68% (155) | resuscitation-promoting factor RpfA |
| M. marinum M | MMAR_3402 | - | 2e-80 | 47.46% (354) | PE-PGRS family protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3222 | - | 3e-09 | 30.22% (182) | prolipoprotein diacylglyceryl transferase |
| M. thermoresistible (build 8) | TH_3241 | - | 4e-07 | 26.34% (186) | PUTATIVE putative FHA domain containing protein |
| M. ulcerans Agy99 | MUL_3341 | sigA | 8e-06 | 27.94% (136) | RNA polymerase sigma factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0445|M.vanbaalenii_PYR-1 -------------------MTSRRWALWLWTLGAGACITLGAGTGVAAAD
Mflv_0299|M.gilvum_PYR-GCK -------------------MTSQRWAIWLGAFGAGACIALGAGHGVAAAD
MMAR_3402|M.marinum_M ------------------------MSTYVIAAPDAFSVASGELAGIEAAV
MAB_0869c|M.abscessus_ATCC_199 ---------------------MSGRHSKPSKASAKAAKVAVAGAGLVGGG
MSMEG_3222|M.smegmatis_MC2_155 -----------MTTTVLAYLPSPSQGVWHLGPVPIRAYALCIIVGIVAAL
TH_3241|M.thermoresistible__bu VGAPPRSKEVMVNVTLGVFVESGTARIVLVDADPPNPVVDQTDLDLAAAD
MUL_3341|M.ulcerans_Agy99 ------------------------MAATKASPETGEPVKRTATKSPAKAG
. .
Mvan_0445|M.vanbaalenii_PYR-1 TETSGGDGPSSQSDDRDASEASSHGAPDQGT------GETPDPNAGDGVD
Mflv_0299|M.gilvum_PYR-GCK SDTADAADTSSQS-------AETRTAADQPA------AREPDEPEARETE
MMAR_3402|M.marinum_M KGAAAAAAPSTTG-IISAAADEVSTAIARLF------GSYADEFQTLSAQ
MAB_0869c|M.abscessus_ATCC_199 LMMAATANAATDG--------EWDQVARCES------GGNWAINTGNGYQ
MSMEG_3222|M.smegmatis_MC2_155 VIGDRRWQARGGEPGVIYDIALWAVPFGLAG------GRIYHVITDWKTY
TH_3241|M.thermoresistible__bu STPDTLVTTVLATAGALTESGHRLVGISLCGPAADRIGPVHDALTGSGLR
MUL_3341|M.ulcerans_Agy99 AKRPTKTANGAPP----------AKRAAKTP------GQADDATTGDAPK
.
Mvan_0445|M.vanbaalenii_PYR-1 ADDS---SDPATVPA-----------------------SVELADDVVRDA
Mflv_0299|M.gilvum_PYR-GCK AEAE---ETDADAAA-----------------------ESEGEGADTDDT
MMAR_3402|M.marinum_M ATRF---QAQFERAL-----------------------SEAGAAYAAAEA
MAB_0869c|M.abscessus_ATCC_199 GGLQ---FSPSTWIN-----------------------SGGGQYAPSAHL
MSMEG_3222|M.smegmatis_MC2_155 FGPTGKGFGAALQIW-----------------------EGGLGIWGAVAF
TH_3241|M.thermoresistible__bu PVTVVDESDAVTAVVRTLAGDETVATLVNDGATVALSMTEAGGVTTPVAT
MUL_3341|M.ulcerans_Agy99 KTRPSARGTKAARGT-----------------------KAPGEGATDPDA
Mvan_0445|M.vanbaalenii_PYR-1 DDEAAQEADAAEEVDADTEADTDVDT------AADTAAEAEPAAESGSGS
Mflv_0299|M.gilvum_PYR-GCK ADVTAEEDAAVESASARKPRAERREA------VAEAASETEPASEQAP--
MMAR_3402|M.marinum_M ANVSPLRALLQEAESLGVFAPIERLIGRPLFGNGSVAAASTGATEASSLL
MAB_0869c|M.abscessus_ATCC_199 ATKEQQIAVAEKVLAGQGRGAWPVCG----RGLSGSTPRTAPAANITP--
MSMEG_3222|M.smegmatis_MC2_155 GAVGAWIACRLRGIPLPAFGDAIAPGIILAQGIGRLGNYFNQELYGRP--
TH_3241|M.thermoresistible__bu EPIDGDPQAAYRTLVERFAADPGAASGLIVMGSLGDGGLPADLVETSPVP
MUL_3341|M.ulcerans_Agy99 NLDTADDLDADPDIDVDSSDDLDLDLDDLEDEDEAASDEAEGDDDSDE--
Mvan_0445|M.vanbaalenii_PYR-1 GSGSASTVVDETPAQPAAADAEPVRATAPEAANVAPAPVTGVKTGRAKLT
Mflv_0299|M.gilvum_PYR-GCK ---------------------EPAQTPAAPTQAVASAP-TGVKTGRAPLT
MMAR_3402|M.marinum_M TSGTN-----------QAGLGGAVNYAAAEALAAPATGATGVKSGFSFLQ
MAB_0869c|M.abscessus_ATCC_199 ----------------------AAHHEEQAAAEPAPAPEPPAEGDEQFVA
MSMEG_3222|M.smegmatis_MC2_155 -----------------TDVPWGLEIYERLNKFGQSDQLNGVSTGQVTAV
TH_3241|M.thermoresistible__bu LRFPDDPEFMLARGATLASLSQDATMAAPVVADELPTTVTPLETADTMQS
MUL_3341|M.ulcerans_Agy99 ----------------------GDDAEYGDGAKAPAAAAPGTASDEEEIA
.
Mvan_0445|M.vanbaalenii_PYR-1 IPVGPH----------DYRTRADWYLPTQADGSVA----ATGVIWLQHGF
Mflv_0299|M.gilvum_PYR-GCK IPVGDK----------GYRTRADWYLPTQGDGTVT----ATGVIWLQHGF
MMAR_3402|M.marinum_M IPIGPSEFLGITIPQFNFPAPAHWYFPTQADGSVN----ANGVIYLQHGF
MAB_0869c|M.abscessus_ATCC_199 EAPEAP---------------AIDEAPAPEEAPAP----EAQDVDFQSGP
MSMEG_3222|M.smegmatis_MC2_155 VHPTFLYELIWNIAVFGFLIWVDRKFRIG-HGRLF----ALYVASYCVGR
TH_3241|M.thermoresistible__bu QQLAYSEVPDEDSDLLGFTDPVDTPGADGPAGGFDPEAEDAEDADAEDAV
MUL_3341|M.ulcerans_Agy99 EPSEKD------------KASGDFVWDEDESEALRQARKDAELTASADSV
.
Mvan_0445|M.vanbaalenii_PYR-1 LGNKASLSKLAQTLSQQTNSIVVAPNLSSFPLACAGCWINGVPMQEAVAA
Mflv_0299|M.gilvum_PYR-GCK LGNKSFVSALARNLSQQTNSIVVAPNLSSFPLACAACWINGVPMREAVAG
MMAR_3402|M.marinum_M GAIGWFYQPLAMQLAQQTNSIVVVPTVPSIPLPFG-MWIGGAQMQQGVGS
MAB_0869c|M.abscessus_ATCC_199 APEE---PAPAPEPAPVDEAQAPAPELIAAPAPEAPVVDEAPAPEEAPAP
MSMEG_3222|M.smegmatis_MC2_155 FWVELMRSDTATEFAGIRVNTFTSTFVFIGAVVYIMLAPKGREEPESLRG
TH_3241|M.thermoresistible__bu RRRQWLIGSSVGALAAVGFATLAVSVAITIEPTSSQQAVRLQEGPVPGKA
MUL_3341|M.ulcerans_Agy99 RAYLKQIGKVALLNAEEEVELAKRIEAGLYATQLMAELTDRGEKLPAAQR
. :
Mvan_0445|M.vanbaalenii_PYR-1 MFLGDRTSLNASANTAGYLGTLPQDFVMSGQSAGGGFATAVGG---YYTE
Mflv_0299|M.gilvum_PYR-GCK MFLDQRTSLTASAQAAGYVGALPEDFVLSGQSAGGGFAAAVGG---FYAA
MMAR_3402|M.marinum_M LFLGSQTALNISANQAGYLGTLPQDFILSGHSAGGGLASIAAG---SYLA
MAB_0869c|M.abscessus_ATCC_199 EAPAADDQVLPYELQS---GPAPAEPAPAPEPAPAPAAAPEIP---LPAG
MSMEG_3222|M.smegmatis_MC2_155 KAADETEEGDEESLVDEAGKELVAAAAGTGVVAAATAAAREDTDDTDGTT
TH_3241|M.thermoresistible__bu FPVAPGQGVEPDGPNWTMIEHLPPPGAPAEVRTFETRALSSSRD-VSKAA
MUL_3341|M.ulcerans_Agy99 RDMMWICRDGDRAKNHLLEANLRLVVSLAKRYTGRGMAFLDLIQEGNLGL
: : *
Mvan_0445|M.vanbaalenii_PYR-1 DP-GNNGSLRGVMMFDGFSFGG-VLTKSLAKLDDPFIPVYQ---------
Mflv_0299|M.gilvum_PYR-GCK NP-LGDNDLRGVVMFDGFAFDG-ALADSLAKLDDPFVPVYQ---------
MMAR_3402|M.marinum_M NLGAATNHLQGVVMFDGVASNSSAFGAAVANLQAANVPIYV---------
MAB_0869c|M.abscessus_ATCC_199 VPDAADIG----------------FAAGKAAFDAGPVASNG---------
MSMEG_3222|M.smegmatis_MC2_155 DPAAASDEPGDEAEPETEAATAVLTADGAEAMSVDEQPDDD---------
TH_3241|M.thermoresistible__bu APAIVNVYRDGTVAVQNAAAPLLPVGPAPALPGTVPVTVPGPVFAEWPEY
MUL_3341|M.ulcerans_Agy99 IRAVEKFDYTKGYKFSTYATWWIRQAITRAMADQARTIRIP---------
Mvan_0445|M.vanbaalenii_PYR-1 ------------------------------IAAPPQPWNSSGASTKELVA
Mflv_0299|M.gilvum_PYR-GCK ------------------------------IAAPSQPWNGKGSSTRELVV
MMAR_3402|M.marinum_M ------------------------------VAAPPQPWNAFGATTNQLVS
MAB_0869c|M.abscessus_ATCC_199 ------------------------------IPTSPEAVAGVVRHLPDPNN
MSMEG_3222|M.smegmatis_MC2_155 ------------------------------EAVDEEAGQEAEEPADELVE
TH_3241|M.thermoresistible__bu VTRLIPDFSRIRPVDLLYFLANLRELLPPLEATTPDPDDGFDIGDIGVLA
MUL_3341|M.ulcerans_Agy99 -------------------------------VHMVEVINKLGRIQRELLQ
:
Mvan_0445|M.vanbaalenii_PYR-1 ARPGQFVGVTLAGGSHADALIGGNALFD----------------FFAQLV
Mflv_0299|M.gilvum_PYR-GCK ARPDQFVGVTLAGGSHSDSLLGGNPITD----------------LLLQLV
MMAR_3402|M.marinum_M LYPGQFTGVEIVNGSHVDSMLGGNPLID----------------FAAQLL
MAB_0869c|M.abscessus_ATCC_199 LPPG-----------TTDVAPGDSRGVS----------------YLKDIV
MSMEG_3222|M.smegmatis_MC2_155 LADEPEGEPEPAAAEEAEPAETIEPDED----------------EIFDAE
TH_3241|M.thermoresistible__bu VVPRDQGVLFSADADAAGPEMIPARLFDPQTPAADKTQLLPPGTTVLDVP
MUL_3341|M.ulcerans_Agy99 DLGREPTPEELAKEMDITPEK-----------------------VLEIQQ
Mvan_0445|M.vanbaalenii_PYR-1 AGFSPPGNTAAVYTLATGWINDMYQGLGPNDGT-GIYGDPDQYIVMGDTA
Mflv_0299|M.gilvum_PYR-GCK TGRSPAGNTAAAYTLANGWINDMYAGLGPADGT-GIYGTPDQYIVMGDTA
MMAR_3402|M.marinum_M TGFSPPGATQAVYTLSSGWINDIWAGADPLNPIYGIYGPTGGYVAPGG-Q
MAB_0869c|M.abscessus_ATCC_199 FAMQTQDVKASDAILALAQR------------------------------
MSMEG_3222|M.smegmatis_MC2_155 LAEALAEAAEDFAVVPESAGSDEAEVAAAESAADAEDGPSDAESAEVPAE
TH_3241|M.thermoresistible__bu TDGDGDDPTAALTGEPTTGDTDESRSQRPGMDTEPAGTPEDSDSDADAGD
MUL_3341|M.ulcerans_Agy99 YAREPISLDQTIGDEGDSQLGDFIEDSEAVVAVDAVSFTLLQDQLQSVLD
Mvan_0445|M.vanbaalenii_PYR-1 AIVLAPPPVVDIDRYLGTWYEVGSVKQFFSIGLVNTKAVYSLNPDASIKV
Mflv_0299|M.gilvum_PYR-GCK AVVLAPPPPVDLDRYLGTWFEVGSVKQFFSIGLVNTKAQYSLNPDGSVRV
MMAR_3402|M.marinum_M AIFLGP--------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155 AAADDAVVSEPAG------------------TVDETEVAEEAAAEAADLE
TH_3241|M.thermoresistible__bu GSVVDETGVDETGPAPDSGPDSGPGSEPTEVTHPTPPAEPTVAPDEPTSR
MUL_3341|M.ulcerans_Agy99 TLSERE--------------------------------------------
Mvan_0445|M.vanbaalenii_PYR-1 ENSGNYFFNNGPESSIVGSALPVDPTNN--KLNVRFFGPPSARPPGNYWI
Mflv_0299|M.gilvum_PYR-GCK ENSGNYFVNNGPQSSIVGSALPVDATNN--RLTVRFFGPPSAAPPGNYWI
MMAR_3402|M.marinum_M ---------------TAGIVLPA---------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155 FESYDAELAEALAEAAEDMAVVVAPAET--AESDEAREPVETDATESEEP
TH_3241|M.thermoresistible__bu PSTSAPAPAPDPDTPTQAPAVQAPPASQEPATRAPATQAPATQAPATQAP
MUL_3341|M.ulcerans_Agy99 ----------------AGVVRLRFGLTDGQPRTLDEIGQVYGVTRERIRQ
Mvan_0445|M.vanbaalenii_PYR-1 VDLDPDYQWAVVTDPTGLSGFLLSRDPVVSADFYQELLDRASVNGVKGWI
Mflv_0299|M.gilvum_PYR-GCK VDLDPEYRWAVVTDPTGLSGFLLSREAVVTDAFYRELLDRASVYGVKARI
MMAR_3402|M.marinum_M --------------------------------------------------
MAB_0869c|M.abscessus_ATCC_199 --------------------------------------------------
MSMEG_3222|M.smegmatis_MC2_155 SEPEEPDAPEAVEAPEALDENADETRAEPAAPAAVATAPVEPEKGRLRRW
TH_3241|M.thermoresistible__bu GTQEPITQAPATEEPATQAPVTQGPATQAPRTVAPQTQAPETVAPQVEAP
MUL_3341|M.ulcerans_Agy99 IESKTMSKLRHPSRSQVLRDYLD---------------------------
Mvan_0445|M.vanbaalenii_PYR-1 TRTRQPAANQTQL--------
Mflv_0299|M.gilvum_PYR-GCK TPTRQPAAQTTTI--------
MMAR_3402|M.marinum_M ---------------------
MAB_0869c|M.abscessus_ATCC_199 ---------------------
MSMEG_3222|M.smegmatis_MC2_155 LRRNR----------------
TH_3241|M.thermoresistible__bu VTTMPQYPVGGGSFGGGADGD
MUL_3341|M.ulcerans_Agy99 ---------------------