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IHSKVRVALAAVAGAAVLPFAVGCSSGSAAAEQPSGNHDAFVQCMTEHGVSAPPGGGHSGPPPEGAPGPP PEGAGGPPGSPADGAGGPPGSPADGSPPPAPLGVDQQTWDAATQACGSLMPGPPPSR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0063 | - | - | 100% (128) | hypothetical protein Mvan_0063 |
| M. vanbaalenii PYR-1 | Mvan_4673 | - | 2e-09 | 50.91% (55) | hypothetical protein Mvan_4673 |
| M. vanbaalenii PYR-1 | Mvan_5106 | - | 9e-08 | 30.40% (125) | hypothetical protein Mvan_5106 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1107 | pra | 1e-07 | 39.74% (78) | proline-rich antigen |
| M. gilvum PYR-GCK | Mflv_2044 | - | 4e-08 | 44.30% (79) | integral membrane protein-like protein |
| M. tuberculosis H37Rv | Rv1078 | pra | 1e-07 | 39.74% (78) | proline-rich antigen |
| M. leprae Br4923 | MLBr_02395 | Ag36 | 5e-06 | 34.94% (83) | proline rich antigenic protein |
| M. abscessus ATCC 19977 | MAB_2532 | - | 3e-06 | 32.69% (104) | hypothetical protein MAB_2532 |
| M. marinum M | MMAR_2737 | apa | 7e-10 | 35.71% (98) | alanine and proline rich secreted protein Apa |
| M. avium 104 | MAV_1202 | - | 2e-08 | 42.65% (68) | Pra protein |
| M. smegmatis MC2 155 | MSMEG_5794 | - | 5e-22 | 42.96% (135) | hypothetical protein MSMEG_5794 |
| M. thermoresistible (build 8) | TH_4426 | - | 3e-06 | 36.47% (85) | PUTATIVE AAA ATPase |
| M. ulcerans Agy99 | MUL_1750 | - | 2e-07 | 41.89% (74) | proline and glycine rich transmembrane protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2737|M.marinum_M --------------------------------------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu VVRPAHPLYCAAVRAELTEPEVRGVRTELAGAAAPTDVVGRLRWTLHALD
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2737|M.marinum_M --------------------------------------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu SDAPPAAQQLTVAAEDALRLGDLGLCERFGRAAVGAAGSGAGLAARLPLA
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2737|M.marinum_M --------------------------------------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu YALAFQGRGREADEVLAAVDSTGLTEHELMAWALPRAANQFWMLSQPERA
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2737|M.marinum_M --------------------------------------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu VAFLRTVRERVSSPTAATTLDALSATFAMNAGRPQQALQTATEVLASPTA
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2737|M.marinum_M --------------------------------------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu DGTAIGWAGAAAALSAARMGRFTEVDALAERAMSAGHPGLLRFTSGFGQT
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2737|M.marinum_M --------------------------------------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu TARQLTGAPDQALALARRLTEIAQLQQPGRAIGELLIAEVLITRGDLDEA
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------------------------------------------------
MUL_1750|M.ulcerans_Agy99 --------------------------------------------------
MMAR_2737|M.marinum_M --------------------------------------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu VALLRAAVKVLTPTGYSWAPLAAMLLARALGEQGAAPEAAIALSRAESRH
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 ------------MTEQPPPGG-------------SYP-PPPPPPGPSGGH
Rv1078|M.tuberculosis_H37Rv ------------MTEQPPPGG-------------SYP-PPPPPPGPSGGH
MLBr_02395|M.leprae_Br4923 ------------MTDQPPPSG-------------SNPTPAPPPPGSSGGY
MAV_1202|M.avium_104 ------------MTDQPPPGG-------------AYP-PPPSSPGSPGGQ
Mflv_2044|M.gilvum_PYR-GCK ------------MTENPP-PG-------------GYPPPPQGGYPPPPPS
MUL_1750|M.ulcerans_Agy99 ------------MSQPPENPGNQADPQDGDQSTPGYPPPPNYGTPPPPPP
MMAR_2737|M.marinum_M ------------MHEVDPNKRRRHGLWTTLALAAVSSASVVSIALPATAS
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu GLKSMLFAPELALARAWTRAARGDRHGAVXXXXACWWWRWWDXXTPPGPP
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 EPPPAAPPGGSGYAPPPPPSSGSGYPP----PPPP--------PGGGAYP
Rv1078|M.tuberculosis_H37Rv EPPPAAPPGGSGYAPPPPPSSGSGYPP----PPPP--------PGGGAYP
MLBr_02395|M.leprae_Br4923 EPSFAPSELGSAYPPPTAPPVGGSYPP----PPPPGGSYPPPPPPGGSYP
MAV_1202|M.avium_104 ---PTPPPGGQ--QPPPPP--GGSYPP----PPPP----------GGSYP
Mflv_2044|M.gilvum_PYR-GCK EGGYPPPPPEGGYPPPPPAGGYQQPPPGGAYPPPPG---------PGGYP
MUL_1750|M.ulcerans_Agy99 PGYGAPPAGPPGYGAPPPPPGYGTPPP----PPPPGYG-----QAPGGYA
MMAR_2737|M.marinum_M ADPAPAPAPSTTAAPPADPNAAPPPADPNAPPPPPADPNAPPPPPADPNA
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu APPAGGGGGGDVETPPGPPAPPAEVEERDDAEIPPGPPSPPAGGGGGGEI
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 PP------PPSAGGYAPP---------PPG---PAIRTMPTESYTPWITR
Rv1078|M.tuberculosis_H37Rv PP------PPSAGGYAPP---------PPG---PAIRTMPTESYTPWITR
MLBr_02395|M.leprae_Br4923 PP------PPSTGAYAPP---------PPG---PAIRSLPKEAYTFWVTR
MAV_1202|M.avium_104 PP------PPPSGGYAPP---------PPG---PAIRTLPTQDYAPWLTR
Mflv_2044|M.gilvum_PYR-GCK PPPGQGGYPPPPGGYGMPPAGFGGGYPPPGQGYPPVGGPPSLDIGAAFSW
MUL_1750|M.ulcerans_Agy99 PP-GYNPPPPPPPGYGPPPAGYS---TQPGFGGP---AKPPFSVGEAISW
MMAR_2737|M.marinum_M PP------PPPADPNAPPPPVVDPNAPEPGRVNNAVGGFSFVVPAGWVES
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu APPPTPGEPGAVIDQSSQNVTVPAPPTPGSETSTALEVFSPPVPPGEVSG
Mvan_0063|M.vanbaalenii_PYR-1 ------------MIHS------KVRVALAAVAGAAVLPFAVGCSSGSAAA
MSMEG_5794|M.smegmatis_MC2_155 ------------MIQT------VLRSTLAGLAAAALVGSVAACSSSEDPA
Mb1107|M.bovis_AF2122/97 VLAAFIDWAPYVVLVG------IGWVIMLVTQTSSCVTSISEYDVGQFCV
Rv1078|M.tuberculosis_H37Rv VLAAFIDWAPYVVLVG------IGWVIMLVTQTSSCVTSISEYDVGQFCV
MLBr_02395|M.leprae_Br4923 VLAYVIDNIPATVLLG------IGMLIQTLTKQEACVTDITQYNVNQYCA
MAV_1202|M.avium_104 ALAFVIDILPYVVVHG------IGTAILVATQQTACITDVTQYAVNQYCA
Mflv_2044|M.gilvum_PYR-GCK SFNKFSKNAVPLIVPT------LVYALVIGVLGAVIFGLASLFP-ADYTS
MUL_1750|M.ulcerans_Agy99 AWNRFTQNAMALVVPI------VIYGLILSAVGGVMVGLFFAFSDRTSTT
MMAR_2737|M.marinum_M DASHLDYGSALLSKMTGEPPMPGQAPPIANDTRVVLGRLDQKLYASAEAT
MAB_2532|M.abscessus_ATCC_1997 -------------MHT-------KARTTVGVAVGSMALIASLIGCGTDAP
TH_4426|M.thermoresistible__bu GGSNMLELPGFPGGTIGGPEIAHNVEVTGPPAEASVPGVDASVATEAGTP
Mvan_0063|M.vanbaalenii_PYR-1 EQPSG---------NHDAFVQCMTEHGVSAPPGGGHSGPPPEGAPGPPPE
MSMEG_5794|M.smegmatis_MC2_155 ASASTGAVTSAETTAFDAYGQCLIEHGMPAPPAG--FGPPPGHPDGPPPP
Mb1107|M.bovis_AF2122/97 SQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTTGSSIGKS-VLKFKVVSE
Rv1078|M.tuberculosis_H37Rv SQPSMIGQLVQWLLSVGGLAYLVWNYGYRQGTIGSSIGKS-VLKFKVVSE
MLBr_02395|M.leprae_Br4923 TQPTGIGMLAFWFAWLMATAYLVWNYGYRQGATGSSIGKT-VMKFKVISE
MAV_1202|M.avium_104 TQNSTLGLVAQWLASIVGLFYLIWNYGYRQGTTGSSVGKS-VMKFKVVSE
Mflv_2044|M.gilvum_PYR-GCK YSGADG---AGMSLDMGPAATIILFLGLIMLFVVGGAISA-AYMAGVLDI
MUL_1750|M.ulcerans_Agy99 YTDAYGNTSETVNMTMSPLASIVMFIGYLAVFAVVLFMHA-GITTGCLDI
MMAR_2737|M.marinum_M NPKAAVRLGSDMGEFFMPYPGTRINQETIPLNANGITGSASYYEVKFSDE
MAB_2532|M.abscessus_ATCC_1997 PRSVG--------TTTQTPAPPPGGSGSVPGGPTGGGGPEGGAGSIPGGP
TH_4426|M.thermoresistible__bu PVPPGPTAPIEHAAETSVPAEVEIPGAEIDHRAEVATPPVDGPPVEVENS
Mvan_0063|M.vanbaalenii_PYR-1 GAGGPPGSPA------------DGAGGPPGSPADGSPPPAP---------
MSMEG_5794|M.smegmatis_MC2_155 PPGGTP------------------PGGPPG---DGQAPPPP---------
Mb1107|M.bovis_AF2122/97 TTGQPIGFG-------------MSVVRQLAHFIDAIICFVG---------
Rv1078|M.tuberculosis_H37Rv TTGQPIGFG-------------MSVVRQLAHFIDAIICFVG---------
MLBr_02395|M.leprae_Br4923 ATGQPIGFG-------------MSVVRQLAHFVDAVICCIG---------
MAV_1202|M.avium_104 VTGQPVGFG-------------MSVVRALAHFVDAIICFIG---------
Mflv_2044|M.gilvum_PYR-GCK ANGQQVEFGSFFKPRNIGAVVIASLIVGIATSIGYVLCIVPGLIVSIFAL
MUL_1750|M.ulcerans_Agy99 ADGKPVTIGSFFKPRNLGMVILTGLLVIVLTAIGSVLCIVPGLIFGFLAQ
MMAR_2737|M.marinum_M SKPNGQIWT--------------GVVGTPAGSTPNEGPPQR-----WFVV
MAB_2532|M.abscessus_ATCC_1997 TGGGGPGGG------------------------GGEIPGGP---------
TH_4426|M.thermoresistible__bu VEVATPPHXX----------GPGAVVDXXXXRRPGADPRPXPLPVAAQLH
Mvan_0063|M.vanbaalenii_PYR-1 ---LGVDQQTWDAATQACGSLMPGPPPSR---------------------
MSMEG_5794|M.smegmatis_MC2_155 ---PGVEQADWDDARAACESLAPASPPR----------------------
Mb1107|M.bovis_AF2122/97 FLFPLWDAKRQTLADKIMTTVCVPI-------------------------
Rv1078|M.tuberculosis_H37Rv FLFPLWDAKRQTLADKIMTTVCVPI-------------------------
MLBr_02395|M.leprae_Br4923 FLFPLWDSKRQTLADKIMTTVCLPI-------------------------
MAV_1202|M.avium_104 FLFPLWDSKRQTLADKIMTTVCLPLDGSESPPS-----------------
Mflv_2044|M.gilvum_PYR-GCK FTTVFIVDRNLSAIDGIKASIAVAKANFLQVFLTWLIFNVLISVGSFVCY
MUL_1750|M.ulcerans_Agy99 FAIIAAVDRSLSPIDSIKSSCATVRAELGNTALSWLVQYAVVLAGELLCF
MMAR_2737|M.marinum_M WLGTSNDPVDKGAAKVLAESIRPWMPPPAPAPAPGEPAPQPGAPEPVPAP
MAB_2532|M.abscessus_ATCC_1997 -----TGSGGPGGGSGCIPNVGCVNVP-----------------------
TH_4426|M.thermoresistible__bu PRPVGCDGPRRPHRGGVVTASRQPRRLTGRVDAPHLHRHRGQPGDAQHQH
Mvan_0063|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_5794|M.smegmatis_MC2_155 --------------------------------------------------
Mb1107|M.bovis_AF2122/97 --------------------------------------------------
Rv1078|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_02395|M.leprae_Br4923 --------------------------------------------------
MAV_1202|M.avium_104 --------------------------------------------------
Mflv_2044|M.gilvum_PYR-GCK --------IGLIVTVPLAVLYMVYAYRTLTGGYVAPATP-----------
MUL_1750|M.ulcerans_Agy99 --------VGMLVGVPVASLIQTYTWRKLSGGQVVELSQPGPPAGLPPGP
MMAR_2737|M.marinum_M --------APAPAAGVAPTVAPAPRTQPT---------------------
MAB_2532|M.abscessus_ATCC_1997 --------------------------------------------------
TH_4426|M.thermoresistible__bu GHHRRQRERGFHGDRATITHTLVFNARLMMLVSALTIESPVTTAYRMAPN
Mvan_0063|M.vanbaalenii_PYR-1 ---------------------------
MSMEG_5794|M.smegmatis_MC2_155 ---------------------------
Mb1107|M.bovis_AF2122/97 ---------------------------
Rv1078|M.tuberculosis_H37Rv ---------------------------
MLBr_02395|M.leprae_Br4923 ---------------------------
MAV_1202|M.avium_104 ---------------------------
Mflv_2044|M.gilvum_PYR-GCK ---------------------------
MUL_1750|M.ulcerans_Agy99 PPGAPPGPQFG----------------
MMAR_2737|M.marinum_M ---------------------------
MAB_2532|M.abscessus_ATCC_1997 ---------------------------
TH_4426|M.thermoresistible__bu AAAAIVPTAYSTVDIPASSTINIVVLA